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Christina Root
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Journal Articles

Potent Target-Specific Efficacy of CAR T Cells Directed Toward the AML and KMT2A-Rearranged Specific Antigen CLEC2A

Danielle C. Kirkey, Grace Hawkins, Melia Blankenfeld, Isabel Lira, Nika Panahi, Margaret G Hines, Seungmin Shin, Tiffany Hylkema, Cyd McKay, Christina Root, Logan K. Wallace, Jack H. Peplinski, Rhonda E. Ries, Concetta Quintarelli, Franco Locatelli, Wei Li, Soheil Meshinchi
Journal: Blood
Blood (2024) 144 (Supplement 1): 2050.
https://doi.org/10.1182/blood-2024-212075
Published: 2024
Journal Articles

Preclinical Efficacy of CD276 (B7-H3) CAR T in Acute Myeloid Leukemia

Isabel Lira, Danielle C. Kirkey, Marilena Nicolaidou, Henrike Muller, Marta Barisa, Melia Blankenfeld, Grace Hawkins, Cyd McKay, Christina Root, Laura Pardo, Michael R. Loken, Tiffany Hylkema, Concetta Quintarelli, Franco Locatelli, John Anderson, Soheil Meshinchi
Journal: Blood
Blood (2024) 144 (Supplement 1): 4793.
https://doi.org/10.1182/blood-2024-206227
Published: 2024
Journal Articles

Effective Dual Targeting of PRAME and WT1 with CD33-Gated ARTEMIS® Antibody-TCR Platform in Acute Myeloid Leukemia

Melia Blankenfeld, Danielle C. Kirkey, Guangyan Xiong, Hongbing Zhang, Grace Hawkins, Isabel Lira, Cyd McKay, Christina Root, Concetta Quintarelli, Franco Locatelli, Cheng Liu, Soheil Meshinchi
Journal: Blood
Blood (2024) 144 (Supplement 1): 3417.
https://doi.org/10.1182/blood-2024-206204
Published: 2024
Journal Articles

Discovery and Immunotherapeutic Targeting of the Tumor-Specific Target LAMP5 in Acute Myeloid Leukemia

Grace Hawkins, Danielle Kirkey, Nika Panahi, Melia Blankenfeld, Isabel Lira, Tiffany Hylkema, Cyd McKay, Christina Root, Jack H. Peplinski, Logan K. Wallace, Rhonda E. Ries, Laura Pardo, Michael R. Loken, Soheil Meshinchi
Journal: Blood
Blood (2024) 144 (Supplement 1): 3413.
https://doi.org/10.1182/blood-2024-204043
Published: 2024
Journal Articles

Potent and Target Specific Cytotoxicity of PRAME TCR Mimic CAR T Cells in KMT2A-Rearranged AML Patient-Derived Xenograft Model

Danielle C Kirkey, Leila Robinson, Tiffany Hylkema, Anisha Loeb, Rhonda E Ries, Cyd McKay, Christina Root, Laura Pardo, Keith R. Loeb, Quy Le, David A. Scheinberg, Soheil Meshinchi
Journal: Blood
Blood (2023) 142 (Supplement 1): 4821.
https://doi.org/10.1182/blood-2023-188391
Published: 2023
Journal Articles

Clonal Analysis Reveals Functional and Transcriptional Heterogeneity of Self-Renewing Fetal Liver Hematopoietic Stem Cells

Takashi Ishida, Adam M Heck, Barbara Varnum-Finney, Stacey Dozono, Cynthia Nourigat-Mckay, Katie Kraskouskas, Rachel Wellington, Olivia Waltner, Christina Root, Dana L Jackson, Cole Trapnell, Shahin Rafii, Irwin D. Bernstein, Brandon Hadland
Journal: Blood
Blood (2022) 140 (Supplement 1): 8574–8575.
https://doi.org/10.1182/blood-2022-156513
Published: 2022