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Lianbo Yu
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Journal Articles

Genome-Wide CRISPR/Cas9 Knockout Screen Reveals Novel LP-168 (Rocbrutinib) Combinations Targeting BCL-2 Protein Members for Chronic Lymphocytic Leukemia

Britten K. Gordon, Ethan C. Whipp, Lianbo Yu, Samon Benrashid, Andrew D. Mitchell, Alexander He, Jazmin Urrutia, Shrilekha Misra, Alexander R. Marr, Tzung-Huei Lai, Naina Karnati, Shanmugapriya Thangavadivel, Kerry A. Rogers, Seema A. Bhat, Nicole R. Grieselhuber, Yi Chen, Fenlai Tan, Stephen P. Anthony, Yu Chen, Deepa Sampath, Rosa Lapalombella, Jennifer A. Woyach
Journal: Blood
Blood (2024) 144 (Supplement 1): 3587.
https://doi.org/10.1182/blood-2024-203522
Published: 2024
Journal Articles

Targeting Covalent and Non-Covalent Btki-Resistant CLL Using the Dual Irreversible/Reversible 4 th Generation BTK Inhibitor LP-168

Britten Gordon, Elizabeth Muhowski, Janani Ravikrishnan, Samon Benrashid, Andrew Mitchell, Alexander He, Shrilekha Misra, Tzung-Huei Lai, Shanmugapriya Thangavadivel, Alexander Marr, Lianbo Yu, Brandi Walker, Elizabeth Perry, Kerry A Rogers, Adam S Kittai, Seema A Bhat, John C. Byrd, Deepa Sampath, Rosa Lapalombella, Weiguo Han, Neil E. Kay, Yi Chen, Fenlai Tan, Stephen P. Anthony, Yu Chen, Jennifer A. Woyach
Journal: Blood
Blood (2023) 142 (Supplement 1): 416.
https://doi.org/10.1182/blood-2023-178259
Published: 2023
Journal Articles

The PKC-β Inhibitor MS-553 Displays Preclinical Efficacy in BTK Inhibitor Resistant Chronic Lymphocytic Leukemia

Britten Gordon, Elizabeth Muhowski, Janani Ravikrishnan, Shanmugapriya Thangavadivel, Samon Benrashid, Alexander He, Shrilekha Misra, Tzung-Huei Lai, Alexander Marr, Lianbo Yu, Brandi Walker, Elizabeth Perry, Nicole R. Grieselhuber, Kerry A Rogers, James S. Blachly, Adam S Kittai, Seema A Bhat, John C. Byrd, Michael Niesman, Kai Zhang, Deepa Sampath, Jennifer A. Woyach
Journal: Blood
Blood (2023) 142 (Supplement 1): 2260.
https://doi.org/10.1182/blood-2023-182024
Published: 2023
Journal Articles

PRMT5 Initiates an Epigenetic Program That Promotes Progression of Chronic Lymphocytic Leukemia

Zachary A Hing, BS, Jordan N. Skinner, B.S., Larry P. Beaver, Tzung-Huei Lai, PhD, Casey B. Cempre, B.S., Bonnie K. Harrington, DVM, Deepa Sampath, PhD, Amy M. Lehman, PhD, Lianbo Yu, PhD, Lapo Alinari, MD PhD, John C. Byrd, MD, Robert A Baiocchi, MD PhD, Rosa Lapalombella, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2487.
https://doi.org/10.1182/blood.V130.Suppl_1.2487.2487
Published: 2017
Journal Articles

A Novel Inhibitor of BET Family Bromodomains Demonstrates In Vivo and I n Vi tro Potency in B-Cell Malignancies

Dalia El-Gamal, PhD, Zachary A. Hing, BS, Shaneice Mitchell, BS, Taylor D. LaFollette, Paul J. Brennan, Joseph M. Flynn, DO, MPH, Jeffrey A. Jones, MD MPH, Farrukh Awan, MD MS, Leslie A. Andritsos, MD, James S. Blachly, MD, Katie Williams, MS, Bonnie K. Harrington, DVM, Virginia M. Goettl, DVM, PhD, Jennifer A. Woyach, MD, Amy M. Lehman, MAS, Lianbo Yu, PhD, John C. Byrd, MD, Rosa Lapalombella, PhD
Journal: Blood
Blood (2015) 126 (23): 318.
https://doi.org/10.1182/blood.V126.23.318.318
Published: 2015
Journal Articles

The Eµ-Myc/TCL1 Transgenic Mouse As a New Aggressive B-Cell Malignancy Model Suitable for Preclinical Therapeutics Testing

Kerry A. Rogers, MD, Dalia El-Gamal, PhD, Harrington K. Bonnie, DVM, Hing A. Zachary, BS, Goettl M. Virginia, DVM, PhD, Mantel Rose, Lisa L. Smith, MS, Lianbo Yu, PhD, Amy J. Johnson, PhD, John C. Byrd, MD, Rosa Lapalombella, PhD, Jennifer A. Woyach, MD
Journal: Blood
Blood (2015) 126 (23): 2752.
https://doi.org/10.1182/blood.V126.23.2752.2752
Published: 2015
Journal Articles

Characterization of CLL exosomes reveals a distinct microRNA signature and enhanced secretion by activation of BCR signaling

Yuh-Ying Yeh, Hatice Gulcin Ozer, Amy M. Lehman, Kami Maddocks, Lianbo Yu, Amy J. Johnson, John C. Byrd
Journal: Blood
Blood (2015) 125 (21): 3297–3305.
https://doi.org/10.1182/blood-2014-12-618470
Published: 2015
Includes: Supplemental data
Journal Articles

Expression of PRMT5 in B-Cell Chronic Lymphocytic Leukemia and Its Significance in Disease Progression and Richter's Transformation

Dalia El-Gamal, PhD, Taylor D LaFollette, Hongshan Lai, Li Chenglong, PhD, Deepa Sampath, PhD, Amy Lehman, Lianbo Yu, John C. Byrd, MD, Robert A. Baiocchi, MD PhD, Rosa Lapalombella, PhD
Journal: Blood
Blood (2014) 124 (21): 2197.
https://doi.org/10.1182/blood.V124.21.2197.2197
Published: 2014
Journal Articles

Overexpression of miR-155 causes expansion, arrest in terminal differentiation and functional activation of mouse natural killer cells

Rossana Trotta, Li Chen, Stefan Costinean, Srirama Josyula, Bethany L. Mundy-Bosse, David Ciarlariello, Charlene Mao, Edward L. Briercheck, Kathleen K. McConnell, Anjali Mishra, Lianbo Yu, Carlo M. Croce, Michael A. Caligiuri
Journal: Blood
Blood (2013) 121 (16): 3126–3134.
https://doi.org/10.1182/blood-2012-12-467597
Published: 2013
Journal Articles

miR-155 regulates IFN-γ production in natural killer cells

Rossana Trotta, Li Chen, David Ciarlariello, Srirama Josyula, Charlene Mao, Stefan Costinean, Lianbo Yu, Jonathan P. Butchar, Susheela Tridandapani, Carlo M. Croce, Michael A. Caligiuri
Journal: Blood
Blood (2012) 119 (15): 3478–3485.
https://doi.org/10.1182/blood-2011-12-398099
Published: 2012
Journal Articles

Silencing of the inhibitor of DNA binding protein 4 (ID4) contributes to the pathogenesis of mouse and human CLL

Shih-Shih Chen, Rainer Claus, David M. Lucas, Lianbo Yu, Jiang Qian, Amy S. Ruppert, Derek A. West, Katie E. Williams, Amy J. Johnson, Fred Sablitzky, Christoph Plass, John C. Byrd
Journal: Blood
Blood (2011) 117 (3): 862–871.
https://doi.org/10.1182/blood-2010-05-284638
Published: 2011
Includes: Supplemental data
Journal Articles

Micro-RNA and Gene Expression In CLL: Network Analysis Elucidating the Complex Role of the NF-κB Signaling Pathway In Disease.

Erin K Hertlein, PhD, Lianbo Yu, Jianying Zhang, Amy J. Johnson, PhD, David Lucas, PhD, Guido Marcucci, MD, David Jarjoura, John C. Byrd, MD
Journal: Blood
Blood (2010) 116 (21): 3642.
https://doi.org/10.1182/blood.V116.21.3642.3642
Published: 2010
Journal Articles

Cyclosporine-induced immune suppression alters establishment of HTLV-1 infection in a rabbit model

Rashade A. H. Haynes, II, Evan Ware, Christopher Premanandan, Bevin Zimmerman, Lianbo Yu, Andrew J. Phipps, Michael D. Lairmore
Journal: Blood
Blood (2010) 115 (4): 815–823.
https://doi.org/10.1182/blood-2009-07-230912
Published: 2010