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Kristin L Koenig
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Journal Articles

A Randomized Phase 2 Trial of 28-Day (Arm A) Versus 14-Day (Arm B) Schedule of Venetoclax + Azacitidine in Newly Diagnosed Acute Myeloid Leukemia Patients ≥ 60 Years

Uma Borate, Ying Huang, Joshua F Zeidner, Ronan T. Swords, Kristin L Koenig, Eytan M. Stein, Maria R. Baer, Wendy Stock, Yazan F Madanat, Rebecca Olin, William Blum, Gary J. Schiller, Tara L. Lin, Emily K Curran, Molly Martycz, Leonard Rosenberg, Sonja Gullen Marcus, Timothy Chen, Mona Stefanos, Ross L Levine, Brian J. Druker, Ashley Owen Yocum, Amy Burd, Alice Mims, John C. Byrd
Journal: Blood
Blood (2024) 144 (Supplement 1): 2907.2.
https://doi.org/10.1182/blood-2024-210967
Published: 2024
Journal Articles

Demographics, Characteristics, Survival and Outcomes in Older, Untreated, Acute Myeloid Leukemia Patients with NPM1 Mutations or KMT2A rearrangements from the Beat AML Master Clinical Trial

Uma Borate, Rina Li Welkie, Ying Huang, Ronan T. Swords, Elie Traer, Eytan M. Stein, Tara L. Lin, Yazan F Madanat, Prapti A. Patel, Robert H. Collins, Maria R. Baer, Vu H. Duong, William Blum, Martha L. Arellano, Wendy Stock, Olatoyosi Odenike, Robert L. Redner, Tibor J. Kovacsovics, Michael W. Deininger, Joshua F Zeidner, Rebecca Olin, Catherine C. Smith, James M. Foran, Gary J. Schiller, Emily K Curran, Kristin L Koenig, Nyla A. Heerema, Timothy Chen, Molly Martycz, Mona Stefanos, Sonja Gullen Marcus, Leonard Rosenberg, Brian J. Druker, Ross L Levine, Amy Burd, Ashley Owen Yocum, Alice Mims, John C. Byrd
Journal: Blood
Blood (2024) 144 (Supplement 1): 1564.
https://doi.org/10.1182/blood-2024-211261
Published: 2024
Journal Articles

Comparison of Two Myeloablative Total-Body Irradiation (MAC-TBI) Regimens: 1200 Cgy Vs 800 Cgy of TBI for Allogeneic Stem Cell Transplantation in Adults with Hematological Malignancies

Gabriela Sanchez-Petitto, Ying Huang, Evandro Bezerra, Jonathan E. Brammer, Hannah Choe, Nathan Denlinger, Polina Shindiapina, Sam Penza, Sarah A Wall, Gregory K Behbehani, James S. Blachly, Bradley Wayne Blaser, Uma Borate, Ann-Kathrin Eisfeld, Nicole R. Grieselhuber, Kristin L Koenig, Karilyn T. Larkin, Meixiao Long, Alice Mims, Andrew Srisuwananukorn, Ayman Saad, Sumithira Vasu, Marcos de Lima
Journal: Blood
Blood (2024) 144 (Supplement 1): 7303.
https://doi.org/10.1182/blood-2024-194146
Published: 2024
Journal Articles

GATA2 -Mutated AML: Clinical Outcomes and Spectrum of Infections in Patients Undergoing or Not Allogeneic Stem Cell Transplantation

Gabriela Sanchez-Petitto, Zeinab El Boghdadly, Deedra Nicolet, Julia Cooper, Ann-Kathrin Eisfeld, Victoria Klein, Michael C Walker, Krzysztof Mrózek, Evandro Bezerra, Jonathan E. Brammer, Nathan Denlinger, Polina Shindiapina, Sam Penza, Sarah A. Wall, Gregory K Behbehani, James S. Blachly, Bradley Wayne Blaser, Uma Borate, Nicole R. Grieselhuber, Kristin L Koenig, Karilyn T. Larkin, Meixiao Long, Alice Mims, Andrew Srisuwananukorn, Sumithira Vasu, Marcos de Lima
Journal: Blood
Blood (2024) 144 (Supplement 1): 7309.
https://doi.org/10.1182/blood-2024-202650
Published: 2024
Journal Articles

Real World Outcomes of Patients (Pts) with Acute Myeloid Leukemia, Myelodysplasia-Related (AML-MR) or Therapy-Related AML (t-AML) Receiving Venetoclax-Based Therapies

Kelly Pugh, Michael C Walker, Deedra Nicolet, Victoria Klein, Krzysztof Mrózek, Gregory K Behbehani, James S. Blachly, Uma Borate, Nicole R. Grieselhuber, Kristin L Koenig, Karilyn T. Larkin, Meixiao Long, Andrew Srisuwananukorn, Ann-Kathrin Eisfeld, Alice Mims
Journal: Blood
Blood (2024) 144 (Supplement 1): 7929.
https://doi.org/10.1182/blood-2024-210135
Published: 2024
Journal Articles

A Phase I Study to Evaluate the Safety and Tolerability of Gemtuzumab Ozogamicin and Midostaurin When Used in Combination with Standard Cytarabine and Daunorubicin Induction for Newly Diagnosed FLT3-Mutated Acute Myeloid Leukemia

Uma Borate, Kaitlyn M. Dvorak-Kornaus, Qiuhong Zhao, Roland B. Walter, Rachel J. Cook, Jennifer N. Saultz, Ronan T. Swords, Nicole R. Grieselhuber, Alice Mims, Karilyn T. Larkin, Kieran D Sahasrabudhe, James S. Blachly, Gregory K Behbehani, Ann-Kathrin Eisfeld, Meixiao Long, Andrew Srisuwananukorn, Kristin L Koenig
Journal: Blood
Blood (2024) 144 (Supplement 1): 4286.
https://doi.org/10.1182/blood-2024-210605
Published: 2024
Journal Articles

Real-World Experience of Venetoclax Target Dosing with Concomitant Posaconazole in Adult Patients with Acute Myeloid Leukemia

Tracelyn Freeman, Alma Habib, Ying Huang, Pooja Kumar, Allyson Waller, Megan Fleming, Kelsey McMillan, Natalia Hartzler, Gregory K Behbehani, James S. Blachly, Bradley Wayne Blaser, Uma Borate, Ann-Kathrin Eisfeld, Nicole R. Grieselhuber, Karilyn T. Larkin, Shinae Lee, Meixiao Long, Alice Mims, Andrew Srisuwananukorn, Kieran D Sahasrabudhe, Kristin L Koenig
Journal: Blood
Blood (2024) 144 (Supplement 1): 2432.
https://doi.org/10.1182/blood-2024-203704
Published: 2024
Journal Articles

A Phase 1, Open-Label, Dose Escalation and Dose Expansion, Multicenter Clinical Trial to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of Lomonitinib (ZE46-0134) in Adults with FLT3 -Mutated Relapsed or Refractory Acute Myeloid Leukemia

Tara L. Lin, Kristin L Koenig, Ronan T. Swords, Eytan M. Stein, Maria R. Baer, Wendy Stock, Yazan F Madanat, Rebecca Olin, William Blum, Gary J. Schiller, Joshua F Zeidner, Emily K Curran, Molly Martycz, Leonard Rosenberg, Sonja Gullen Marcus, Timothy Chen, Mona Stefanos, Amy Burd, Ashley Owen Yocum, Ross L Levine, Brian J. Druker, Uma Borate, John C. Byrd, Alice Mims
Journal: Blood
Blood (2024) 144 (Supplement 1): 2883.4.
https://doi.org/10.1182/blood-2024-208822
Published: 2024
Journal Articles

IDH2 Mutation Is Associated with Favorable Outcome Among Older Adults with Newly Diagnosed Acute Myeloid Leukemia Treated with Lower-Intensity Therapy

Fieke W Hoff, Ying Huang, Rina Li Welkie, Ronan T. Swords, Elie Traer, Eytan M. Stein, Tara L. Lin, Prapti A. Patel, Robert H. Collins, Maria R. Baer, Vu H. Duong, William Blum, Martha L. Arellano, Wendy Stock, Olatoyosi Odenike, Robert L. Redner, Tibor J. Kovacsovics, Michael W. Deininger, Joshua F Zeidner, Rebecca Olin, Catherine C. Smith, James M. Foran, Gary J. Schiller, Emily K Curran, Kristin L Koenig, Nyla A. Heerema, Timothy Chen, Molly Martycz, Mona Stefanos, Sonja Gullen Marcus, Leonard Rosenberg, Brian J. Druker, Ross L Levine, Amy Burd, Ashley Owen Yocum, Uma Borate, Alice Mims, John C. Byrd, Yazan F. Madanat
Journal: Blood
Blood (2024) 144 (Supplement 1): 4325.
https://doi.org/10.1182/blood-2024-202596
Published: 2024
Journal Articles

Outcomes and Survival in Newly Diagnosed, Older, Acute Myeloid Leukemia Patients from the Beat AML Master Trial in the Venetoclax/Azacitidine Age

Uma Borate, Ying Huang, Rina Li Welkie, Ronan T. Swords, Elie Traer, Eytan M. Stein, Tara L. Lin, Yazan F Madanat, Prapti A. Patel, Robert H. Collins, Maria R. Baer, Vu H. Duong, William Blum, Martha L. Arellano, Wendy Stock, Olatoyosi Odenike, Robert L. Redner, Tibor J. Kovacsovics, Michael W. Deininger, Joshua F Zeidner, Rebecca Olin, Catherine C. Smith, James M. Foran, Gary J. Schiller, Emily K Curran, Kristin L Koenig, Nyla A. Heerema, Timothy Chen, Molly Martycz, Mona Stefanos, Sonja Gullen Marcus, Leonard Rosenberg, Brian J. Druker, Ross L Levine, Amy Burd, Ashley Owen Yocum, Alice Mims, John C. Byrd
Journal: Blood
Blood (2024) 144 (Supplement 1): 4324.
https://doi.org/10.1182/blood-2024-211178
Published: 2024
Journal Articles

Beat AML S8 Group 2: Gilteritinib (GILT) in Combination with Decitabine (DEC) and Venetoclax (VEN) in Untreated FLT3 Mutated Acute Myeloid Leukemia (AML) Patients Age ≥60 with High and Low Variant Allele Frequency (VAF)

Qiuying (Selina) Liu, Rina Li Welkie, Ying Huang, Ronan T. Swords, Tara L Lin, Kristin L Koenig, Yazan F. Madanat, Prapti A. Patel, Robert H. Collins, William Blum, Martha Arellano, Maria R. Baer, Wendy Stock, Tibor J. Kovacsovics, Rebecca Olin, Emily K Curran, Eytan M. Stein, Gary J. Schiller, Joshua F. Zeidner, Robert L. Redner, Nyla A. Heerema, Molly Martycz, Leonard Rosenberg, Sonja Gullen Marcus, Timothy Chen, Mona Stefanos, Ross L Levine, Brian J. Druker, Ashley Owen Yocum, Amy Burd, Alice Mims, Uma M. Borate, John C. Byrd, Elie Traer
Journal: Blood
Blood (2023) 142 (Supplement 1): 5933.
https://doi.org/10.1182/blood-2023-179609
Published: 2023
Journal Articles

Genomic Characterization of Newly Diagnosed Acute Myeloid Leukemia in Patients Age 60 Years and Older; A Report from the Beat AML Master Trial

Fieke W Hoff, Ying Huang, Rina Li Welkie, Ronan T. Swords, Elie Traer, Eytan M. Stein, Tara L Lin, Prapti A. Patel, Robert H. Collins, Maria R. Baer, Vu H. Duong, William Blum, Martha Arellano, Wendy Stock, Olatoyosi Odenike, Robert L. Redner, Tibor J. Kovacsovics, Michael W. Deininger, Joshua F. Zeidner, Rebecca Olin, Catherine C. Smith, James M. Foran, Gary J. Schiller, Emily K Curran, Kristin L Koenig, Nyla A. Heerema, Timothy Chen, Molly Martycz, Mona Stefanos, Sonja Gullen Marcus, Leonard Rosenberg, Brian J. Druker, Ross L Levine, Amy Burd, Ashley Owen Yocum, Uma M. Borate, Alice Mims, John C. Byrd, Yazan F. Madanat
Journal: Blood
Blood (2023) 142 (Supplement 1): 4296.
https://doi.org/10.1182/blood-2023-187044
Published: 2023
Journal Articles

A Randomized Phase 2 Trial of 28-Day (Arm A) Versus 14-Day (Arm B) Schedule of Venetoclax + Azacitidine in Newly Diagnosed Acute Myeloid Leukemia Patients ≥ 60 Years

Uma M. Borate, Ying Huang, Mary F. Johnson, Joshua F. Zeidner, Ronan T. Swords, Kristin L Koenig, Eytan M. Stein, Maria R. Baer, Wendy Stock, Yazan F. Madanat, Rebecca Olin, William Blum, Gary J. Schiller, Tara L Lin, Robert L. Redner, Emily K Curran, Nyla A. Heerema, Molly Martycz, Leonard Rosenberg, Sonja Gullen Marcus, Timothy Chen, Mona Stefanos, Ross L Levine, Brian J. Druker, Ashley Owen Yocum, Amy Burd, Alice Mims, John C. Byrd
Journal: Blood
Blood (2023) 142 (Supplement 1): 1535.
https://doi.org/10.1182/blood-2023-187383
Published: 2023
Journal Articles

Brd4 Inhibition Abrogates Inflammation and Self-Renewal in a Murine Model of Tet2 Mutated Clonal Hematopoiesis

Alexander Marr, Madeline Halpin, Dominique Corbin, Britten Gordon, Samon Benrashid, Ethan C. Whipp, Mehdi Gharghabi, Jean Truxall, Olivia Cahn, Kristin L Koenig, Karilyn T. Larkin, Jennifer A. Woyach, Rosa Lapalombella, Nicole R. Grieselhuber
Journal: Blood
Blood (2023) 142 (Supplement 1): 4070.
https://doi.org/10.1182/blood-2023-179237
Published: 2023
Journal Articles

Influence of Pre-Treatment Features and Therapy Choice By Physicians on Overall Survival in Older Adults with Acute Myeloid Leukemia: A Report from the Beat AML Master Trial

Uma M. Borate, Ying Huang, Rina Li Welkie, Ronan T. Swords, Elie Traer, Eytan M. Stein, Tara L Lin, Yazan F. Madanat, Prapti A. Patel, Robert H. Collins, Maria R. Baer, Vu H. Duong, William Blum, Martha Arellano, Wendy Stock, Olatoyosi Odenike, Robert L. Redner, Tibor J. Kovacsovics, Michael W. Deininger, Joshua F. Zeidner, Rebecca Olin, Catherine C. Smith, James M. Foran, Gary J. Schiller, Emily K Curran, Kristin L Koenig, Nyla A. Heerema, Timothy Chen, Molly Martycz, Mona Stefanos, Sonja Gullen Marcus, Leonard Rosenberg, Brian J. Druker, Ross L Levine, Amy Burd, Ashley Owen Yocum, Alice Mims, John C. Byrd
Journal: Blood
Blood (2023) 142 (Supplement 1): 4332.
https://doi.org/10.1182/blood-2023-181886
Published: 2023
Journal Articles

A Phase 1b/2 Trial of Liposomal Cytarabine and Daunorubicin (CPX-351) in Intermediate to High-Risk Acute Myeloid Leukemia for Patients Who Have Failed an Initial Cycle of Induction Chemotherapy

Corbin Pontious, Ramiro Garzon, James S. Blachly, Bradley Wayne Blaser, Hannah Choe, Nicole R. Grieselhuber, Meixiao Long, Sumithira Vasu, Sarah A Wall, Karilyn T. Larkin, Ann-Kathrin Eisfeld, Kristin L Koenig, Kieran D Sahasrabudhe, Gabriela Sanchez-Petitto, Ayman Saad, Bhavana Bhatnagar, Justin Lyberger, Uma M. Borate, Alice Mims, Brian A. Jonas, Gregory K Behbehani
Journal: Blood
Blood (2023) 142 (Supplement 1): 5946.
https://doi.org/10.1182/blood-2023-184344
Published: 2023
Journal Articles

A Phase II Study of Clinical Efficacy of Venetoclax in Combination with Azacitidine in Patients with Therapy Related Myelodysplastic Syndrome (t-MDS)

Uma M. Borate, Kaitlyn M. Dvorak-Kornaus, Qiuhong Zhao, Kristin L Koenig, Ann-Kathrin Eisfeld, Yazan F. Madanat
Journal: Blood
Blood (2023) 142 (Supplement 1): 6504.
https://doi.org/10.1182/blood-2023-190082
Published: 2023
Journal Articles

LP-118, a Selective Bcl-2 Inhibitor with Tuned Bcl-Xl Activity, Causes Myeloid Differentiation and Cell Death in Acute Myeloid Leukemia (AML)

Kristin L Koenig, Colin Brame, Steven Sher, Larry Beaver, Casey B. Cempre, Katie Williams, Matthew Purcell, Bonnie Harrington, Yi Chen, Felai Tan, Stephen P. Anthony, Yu Chen, Yue Shen, John C. Byrd, Rosa Lapalombella
Journal: Blood
Blood (2022) 140 (Supplement 1): 9068–9069.
https://doi.org/10.1182/blood-2022-170578
Published: 2022
Journal Articles

Characterizing the Development of Secondary Myelodysplastic Syndrome (MDS) with Antecedent or Concurrent Chronic Lymphocytic Leukemia (CLL) in the Era of Small Molecule Inhibitors for the Treatment of CLL

Kristin L Koenig, Prachi Jain, Ying Huang, Kerry A. Rogers, Seema A. Bhat, Jennifer A. Woyach, Michael R. Grever, Uma Borate, Alice S. Mims, Daniel Jones, Cecelia Miller, James S. Blachly, Adam S Kittai
Journal: Blood
Blood (2022) 140 (Supplement 1): 4071–4073.
https://doi.org/10.1182/blood-2022-168274
Published: 2022