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Journal Articles

Targeting Inflammation in Tet2 Mutant Clonal Hematopoiesis Via Inhibition of Brd4 Demonstrates Activity in Both Murine and Human Models

Alexander R. Marr, Madeline Halpin, Dominique L. Corbin, Britten K. Gordon, Samon Benrashid, Ethan C. Whipp, Jean Truxall, Olivia Cahn, Bethany L. Mundy-Bosse, Julia Cooper, Marina Beltrami Moreira, James S. Blachly, Uma Borate, Jennifer A. Woyach, Rosa Lapalombella, Nicole R. Grieselhuber

Blood (2024) 144 (Supplement 1): 2661.

https://doi.org/10.1182/blood-2024-203526

Published: 2024

Journal Articles

Temporally Controlled MYC Overexpression in Chronic Lymphocytic Leukemia Accelerates Progression and Promotes Large B Cell Lymphoma Transformation

Ethan C. Whipp, Krithik Tella, Aidan Macaskill, Steven Sher, Casey Cempre, Jean Truxall, Mehdi Gharghabi, Fang Hao, Alexander R. Marr, Madeline Halpin, Pearlly S. Yan, Jennifer A. Woyach, Rosa Lapalombella

Blood (2024) 144 (Supplement 1): 2978.

https://doi.org/10.1182/blood-2024-210328

Published: 2024

Journal Articles

Brd4 Inhibition Abrogates Inflammation and Self-Renewal in a Murine Model of Tet2 Mutated Clonal Hematopoiesis

Alexander Marr, Madeline Halpin, Dominique Corbin, Britten Gordon, Samon Benrashid, Ethan C. Whipp, Mehdi Gharghabi, Jean Truxall, Olivia Cahn, Kristin L Koenig, Karilyn T. Larkin, Jennifer A. Woyach, Rosa Lapalombella, Nicole R. Grieselhuber

Blood (2023) 142 (Supplement 1): 4070.

https://doi.org/10.1182/blood-2023-179237

Published: 2023

Journal Articles

Development of a Fully Immunocompetent Adoptive Transfer In Vivo Model of Npm1 cA ;Idh2 R140Q ;Flt3 ITD AML

Chia Sharpe, Mariah Johnson, Sydney Fobare, Ola A. Elgamal, Bonnie K. Harrington, Allison Mustonen, Kinsey Bryant, Carolyn Cheney, James R. Lerma, Jean Truxall, Casie Furby, Marissa Long, Kaytlynn Fyock, Alan Shih, Ross L Levine, Erin K. Hertlein, John C. Byrd

Blood (2023) 142 (Supplement 1): 1386.

https://doi.org/10.1182/blood-2023-189975

Published: 2023

Journal Articles

A Novel Ptpn11 E76K / Npm1 cA Murine Model of AML Identifies a Unique Immune Population Relevant to Human Disease

Sydney Fobare, Chia Sharpe, Carolyn Cheney, Allison Mullaney, Casie Furby, Marissa Long, Jean Truxall, Megan Johnstone, Ann-Kathrin Eisfeld, John C. Byrd, Erin Hertlein

Blood (2022) 140 (Supplement 1): 5831–5832.

https://doi.org/10.1182/blood-2022-160093

Published: 2022