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Rachel J. Cook
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Journal Articles

OPTIMIZE: A Phase II Study of Reduced Dose Post Transplantation Cyclophosphamide As GVHD Prophylaxis in Adult Patients with Hematologic Malignancies Receiving HLA-Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation

Jeffery J. Auletta, Steven M. Devine, Heather E. Stefanski, Stephen R. Spellman, Todd E. Defor, Brent R. Logan, Brandan J. Butler, Mahasweta Gooptu, Brian C. Shaffer, Antonio M. Jimenez Jimenez, Sameem Abedin, Dipenkumar Modi, MHD Monzr M. Al Malki, Rachel J. Cook
Journal: Blood
Blood (2024) 144 (Supplement 1): 3514.1.
https://doi.org/10.1182/blood-2024-198252
Published: 2024
Journal Articles

PTPN11 Mutations Are Associated with Shorter Survival in Patients with Acute Myeloid Leukemia Treated with Hypomethylating Agents and Venetoclax

Vishvaas I Ravikumar, Jessica T. Leonard, Laura F. Newell, Arpita Gandhi, Gabrielle Meyers, Brandon Hayes-Lattin, Richard T. Maziarz, Rachel J. Cook, Elie Traer, Ronan T. Swords, Jennifer N. Saultz, Jeffrey W. Tyner, Mael Heiblig, Joshua F Zeidner, Daniel A Pollyea, Curtis A Lachowiez
Journal: Blood
Blood (2024) 144 (Supplement 1): 4312.
https://doi.org/10.1182/blood-2024-201231
Published: 2024
Journal Articles

A Phase I Study to Evaluate the Safety and Tolerability of Gemtuzumab Ozogamicin and Midostaurin When Used in Combination with Standard Cytarabine and Daunorubicin Induction for Newly Diagnosed FLT3-Mutated Acute Myeloid Leukemia

Uma Borate, Kaitlyn M. Dvorak-Kornaus, Qiuhong Zhao, Roland B. Walter, Rachel J. Cook, Jennifer N. Saultz, Ronan T. Swords, Nicole R. Grieselhuber, Alice Mims, Karilyn T. Larkin, Kieran D Sahasrabudhe, James S. Blachly, Gregory K Behbehani, Ann-Kathrin Eisfeld, Meixiao Long, Andrew Srisuwananukorn, Kristin L Koenig
Journal: Blood
Blood (2024) 144 (Supplement 1): 4286.
https://doi.org/10.1182/blood-2024-210605
Published: 2024
Journal Articles

NCAM1 (CD56) As a Predictor of Response to Standard Intensive Induction in Newly Diagnosed Acute Myeloid Leukemia

Jennifer N. Saultz, Manoj Rai, Andy Kaempf, Sanjog Bastola, Hyun Cho, Nicola Long, Curtis A. Lachowiez, Gabrielle Meyers, Jessica T. Leonard, Arpita Gandhi, Laura F. Newell, Brandon Hayes-Lattin, Richard T. Maziarz, Rachel J. Cook, Elie Traer, Ronan T. Swords, Jeffrey W. Tyner
Journal: Blood
Blood (2024) 144 (Supplement 1): 2859.
https://doi.org/10.1182/blood-2024-211860
Published: 2024
Journal Articles

Prognostic Understanding for Older, Medically Infirm, and/or Frail Recipients of Allogeneic Hematopoietic Cell Transplantation in an Ongoing Seamless Phase 2/3 Randomized Interventional Trial (ACE-BMT)

Elizabeth T. Loggers, James Fausto, Matthew Givens, Mei-Ean Yeow, Reena V. Jayani, Hassan B Alkhateeb, Laura A Schoenherr, Michael W. Rabow, Mark B Juckett, George Carrum, Joseph Uberti, Kyle Neale, Santiago Lopez, Diana Martins-Welch, Jeanette G Ferrer, Laura S Rhee, Drew A Rosielle, Susan McInnes, Jason A Webb, Rachel J. Cook, Elisheva Newman, Ronald Sobecks, Laura Johnston, Mohamed Sorror
Journal: Blood
Blood (2024) 144 (Supplement 1): 2297.
https://doi.org/10.1182/blood-2024-212281
Published: 2024
Journal Articles

Impact of Social Determinants of Health on Access to Blood and Marrow Transplantation for Acute Myeloid Leukemia

Somya Khare, Rachel J. Cook, Amrita Desai, Arpita Gandhi, Kelli Goslee, Brandon Hayes-Lattin, Curtis A Lachowiez, Jessica T. Leonard, Richard T. Maziarz, Gabrielle Meyers, Laura F. Newell, Jennifer N. Saultz, Ronan T. Swords, Elie Traer, Eneida R Nemecek
Journal: Blood
Blood (2024) 144 (Supplement 1): 2292.
https://doi.org/10.1182/blood-2024-209407
Published: 2024
Journal Articles

Immunophenotypic Markers CD7 and CD56 Improve Risk Stratification of Frontline Hypomethylating Agents + Venetoclax in Newly Diagnosed AML

Curtis A Lachowiez, Daniel T Peters, Jacob Fang, Andy Kaempf, Jessica T. Leonard, Laura F. Newell, Arpita Gandhi, Gabrielle Meyers, Brandon Hayes-Lattin, Richard T. Maziarz, Rachel J. Cook, Elie Traer, Ronan T. Swords, Jeffrey W. Tyner, Joshua F Zeidner, Daniel A Pollyea, Jennifer N. Saultz
Journal: Blood
Blood (2024) 144 (Supplement 1): 4314.
https://doi.org/10.1182/blood-2024-202118
Published: 2024
Journal Articles

Purine-Analog Based Intensive Chemotherapy (IC) Combined with Venetoclax (VEN) Is Highly Active in Newly Diagnosed (ND) and Relapsed/Refractory (R/R) Acute Myeloid Leukemia (AML)

Curtis A Lachowiez, Adam Julian Cohen-Nowak, Talha Khan, Joanna Cwykiel, Bukky Florence Tabiti, Irum Khan, Shira N. Dinner, Justin Grenet, Aya Agha, Jennifer N. Saultz, Arpita Gandhi, Gabrielle Meyers, Laura F. Newell, Jessica T. Leonard, Brandon Hayes-Lattin, Elie Traer, Richard T. Maziarz, Rachel J. Cook, Ronan T. Swords, Jessica Kaplan Altman, Yasmin Abaza
Journal: Blood
Blood (2024) 144 (Supplement 1): 2887.
https://doi.org/10.1182/blood-2024-203361
Published: 2024
Journal Articles

A Phase 1 Study of the Oral CDK9 Inhibitor Voruciclib in Combination with Venetoclax in Relapsed/Refractory (R/R) Acute Myeloid Leukemia (AML)

Yesid Alvarado-Valero, Rachel J. Cook, Shira N. Dinner, Michael Keng, Kebede Begna, Sameem Abedin, MHD Monzr M. Al Malki, Vijaya Raj Bhatt, Nathalie Javidi-Sharifi, Prabhu Rajagopolan, Sandra Wiley, Richard G Ghalie, Matthew S. Davids
Journal: Blood
Blood (2024) 144 (Supplement 1): 2878.
https://doi.org/10.1182/blood-2024-198718
Published: 2024
Journal Articles

Phase 1 Trial Testing the Novel Combination Therapy of Entrectinib and ASTX727 in TP53 Mutated Relapsed/Refractory Acute Myeloid Leukemia Patients

Cristina Tognon, Shikha Mishra, Andy Kaempf, Byung Park, Sunil K Joshi, Ariane Huang, Stephen E. Kurtz, Luca Sax, Christopher A. Eide, Kara Johnson, Rachel Mahoney, Michael James Lue, Nicole Tong, Lisa Guiducci, Tara Lundberg Willians, Emma Indira Solanki, Rachel J. Cook, Jessica T. Leonard, Curtis A Lachowiez, Gabrielle Meyers, Jennifer N. Saultz, Elie Traer, Jeffrey W. Tyner, Uma Borate, Ronan T. Swords
Journal: Blood
Blood (2024) 144 (Supplement 1): 1498.
https://doi.org/10.1182/blood-2024-208505
Published: 2024
Journal Articles

Breakthrough CMV Viremia Outcomes of Letermovir Prophylaxis in Haploidentical Stem Cell Transplant with Post-Transplant Cyclophosphamide

Arthur Nguyen, Joseph S Bubalo, Jennifer N. Saultz, Brandon Hayes-Lattin, Andy Chen, Rachel J. Cook, Arpita Gandhi, Jessica Leonard, Richard T. Maziarz, Yazan Migdady, Eneida R. Nemecek, Levanto Schachter
Journal: Blood
Blood (2022) 140 (Supplement 1): 12856–12858.
https://doi.org/10.1182/blood-2022-156011
Published: 2022
Journal Articles

SEL24/MEN1703 Inhibits PIM/FLT3 Downstream Target in Acute Myeloid Leukemia (AML) Patients: Results of the Pharmacodynamics (PD) Assay and Genomic Profiling in the First-in-Human Diamond-01 Trial

Alessandro Paoli, Daniela Bellarosa, Alessandro Bressan, Francesco Bertolini, Scott R. Solomon, Pau Montesinos, Sudipto Mukherjee, Stephen A Strickland, Giovanni Marconi, Armando Santoro, Roland B. Walter, Rachel J. Cook, Maria Calbacho, Susana Vives, Salman Fazal, Farhad Ravandi, Krzysztof Brzozka, Tomasz Rzymski, Milena Mazan, Simone Baldini, Niccolò Ravenni, Monica Binaschi, Dirk Laurent, Andrea Pellacani
Journal: Blood
Blood (2021) 138 (Supplement 1): 3436.
https://doi.org/10.1182/blood-2021-150277
Published: 2021
Journal Articles

FLT3-Mutated Acute Myeloid Leukemia Using a Novel Regimen of Gemtuzumab Ozogamicin and Midostaurin in Combination with Standard Cytarabine and Daunorubicin Induction Therapy

Uma Borate, Andy Kaempf, Jessica Minnier, Shikha Misra, Shaun Goodyear, Gabrielle Meyers, Jennifer N. Saultz, Elie Traer, Ronan Swords, Rachel J. Cook, Sammantha Avaylon, Melissa Mackey, Brianna Norris, Roland B. Walter
Journal: Blood
Blood (2021) 138 (Supplement 1): 1269.
https://doi.org/10.1182/blood-2021-152791
Published: 2021
Journal Articles

SY-1425, a Potent and Selective RARα Agonist, in Combination with Azacitidine Demonstrates a High Complete Response Rate and a Rapid Onset of Response in RARA-Positive Newly Diagnosed Unfit Acute Myeloid Leukemia

Stephane De Botton, Thomas Cluzeau, MDPhD, Carlos Enrique Vigil, MD, Rachel J. Cook, MD, Philippe Rousselot, MDPhD, David A Rizzieri, MD, Jane L. Liesveld, MD, Pierre Fenaux, MD PhD, Thorsten Braun, MD PhD, Anne Banos, MD, Michael R. Savona, MD, Don Park, MD, Michael J. Kelly, MD MPH, MS, Angela Volkert, Li Zhou, PhD, Qing Kang-Fortner, PhD, David A. Roth, MD, Eytan M. Stein, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 4–5.
https://doi.org/10.1182/blood-2020-134600
Published: 2020
Journal Articles

Initial Results from a Biomarker-Directed Phase 2 Trial of SY-1425, a Potent and Selective RARα Agonist, in Combination with Azacitidine in Relapsed/Refractory Acute Myeloid Leukemia

Eytan M. Stein, MD, Stephane De Botton, Thomas Cluzeau, MDPhD, Arnaud Pigneux, MD PhD, Jane L. Liesveld, MD, Rachel J. Cook, MD, Philippe Rousselot, MDPhD, David A Rizzieri, MD, Thorsten Braun, MD PhD, Dale L. Bixby, MD, Gail J. Roboz, MD, Delphine Lebon, MD, Mael Heiblig, Michael J. Kelly, MD MPH, MS, Angela Volkert, Li Zhou, PhD, Qing Kang-Fortner, PhD, David A. Roth, MD, Pierre Peterlin, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 6–7.
https://doi.org/10.1182/blood-2020-134602
Published: 2020
Journal Articles

Early Infection after Allogeneic Transplant Increases NRM without Influencing Relapse Rate

Jennifer N Saultz, DO, Kaycee Moshofsky, BS, Andy Kaempf, MS, Guang Fan, MD PhD, Gabrielle Meyers, Rachel J. Cook, MD, Richard T. Maziarz, MD, Peggy Appel, Francisco Tria, MD, Staci Williamson, MS
Journal: Blood
Blood (2020) 136 (Supplement 1): 21.
https://doi.org/10.1182/blood-2020-142048
Published: 2020
Journal Articles

Feasibility and Cost Analysis of Day 4 Granulocyte Colony-Stimulating Factor Mobilized Peripheral Blood Progenitor Cell Collection from HLA-Matched Sibling Donors

Laura F. Newell, MD, Rebekah Knight, Kelsea Shoop, Sara Murray, Rogelyn Kwock, NP, Carol Jacoby, NP, Susan Slater, NP, Bryon Allen, NP, Brad Cota, MBA, Peggy Appel, Rachel J. Cook, MD, Richard T. Maziarz, MD, Gabrielle Meyers, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4558.
https://doi.org/10.1182/blood-2018-99-120342
Published: 2018
Journal Articles

Early Results from a Biomarker-Directed Phase 2 Trial of Sy-1425 in Combination with Azacitidine or Daratumumab in Non-APL Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS)

Rachel J. Cook, MD, Tamara Moyo, MD PhD, Jane L. Liesveld, MD, David A. Rizzieri, MD, Eytan M. Stein, MD, Stephane De Botton, MD PhD, Gail J. Roboz, MD, Mikkael A. Sekeres, MD MS, Joseph G. Jurcic, MD, Azra Raza, MD, Robert L. Redner, MD, Dale L. Bixby, MD PhD, Jorge E. Cortes, MD, Kristin Stephens, Angela Volkert, Qing Kang, PhD, Emmanuelle Di Tomaso, PhD, David A. Roth, MD, Carlos E Vigil, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2735.
https://doi.org/10.1182/blood-2018-99-111285
Published: 2018
Journal Articles

A Phase 1/2 Study of the Oral Novel JAK1 Inhibitor INCB052793 As Monotherapy and in Combination with Standard Therapies in Patients with Advanced Hematologic Malignancies

Amer M. Zeidan, MD, Rachel J. Cook, MD, Rodolfo Bordoni, MD, Ekaterine Asatiani, MD, Gongfu Zhou, Théa Faivre, Michael Byrne, MD, Michael R. Savona, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 640.
https://doi.org/10.1182/blood.V130.Suppl_1.640.640
Published: 2017
Journal Articles

Healthcare Consumption Amongst Older Patients with High Risk AML Treated with Hypomethylating Agents Is Similar to That of Patients Receiving Induction Chemotherapy

Curtis A Lachowiez, MD, Matthew Kearney, MD, Gabrielle Meyers, MD, Rachel J. Cook, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2155.
https://doi.org/10.1182/blood.V130.Suppl_1.2155.2155
Published: 2017