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Journal Articles

Initial Results of a First-in-Human, Phase I Study Point-of-Care Manufacturing of Trispecific CAR-T Cells Targeting CD19/20/22 in B-Cell Malignancies

Blood (2024) 144 (Supplement 1): 2078.

https://doi.org/10.1182/blood-2024-207532

Published: 2024

Journal Articles

Evaluating the Safety and Efficacy of Anti-HIV Transgenic Cells in a Humanized Mouse Model (NOD/SCIDγ c −/− ) for HIV Stem Cell Gene Therapy.

Joseph S. Anderson, Ph.D., Jon Walker, Louisa Wirthlin, John Javien, Jan A. Nolta, Ph.D., Gerhard Bauer

Blood (2008) 112 (11): 2352.

https://doi.org/10.1182/blood.V112.11.2352.2352

Published: 2008

Journal Articles

In Vivo Biosafety Model To Assess Risk of Adverse Events from Retroviral and Lentiviral Vectors.

Gerhard Bauer, Mo Dao, Ph.D., Scott Case, Ph.D., Todd Meyerrose, Ph.D., Louisa Wirthlin, Phillip Herrbrich, Ph.D., Ping Zhou, Ph.D., Xiuli Wang, Ph.D., Susie Csik, Jesusa Arevalo, Dianne Skelton, Jon Walker, Karen Pepper, Gay Crooks, MD, Donald Kohn, MD, Jan Nolta, Ph.D.

Blood (2007) 110 (11): 2595.

https://doi.org/10.1182/blood.V110.11.2595.2595

Published: 2007

Journal Articles

Adult Human Stem Cells Exert Therapeutic Effects To Repair Damaged Tissues in Xenograft Systems through Secretion of Trophic Factors Rather Than Direct Incorporation and Expansion.

Claus Sondergaard, PhD, David Hess, Ph.D., Ivana Rosova, Sarah Hohm, Louisa Wirthlin, Ryan Lahey, Matt Lindsey, Jon Walker, Gerhard Bauer, Ping Zhou, Ph.D., Jan Nolta, Ph.D.

Blood (2007) 110 (11): 3693.

https://doi.org/10.1182/blood.V110.11.3693.3693

Published: 2007

Journal Articles

Selection based on CD133 and high aldehyde dehydrogenase activity isolates long-term reconstituting human hematopoietic stem cells

David A. Hess, Louisa Wirthlin, Timothy P. Craft, Phillip E. Herrbrich, Sarah A. Hohm, Ryan Lahey, William C. Eades, Michael H. Creer, Jan A. Nolta

Blood (2006) 107 (5): 2162–2169.

https://doi.org/10.1182/blood-2005-06-2284

Published: 2006

Journal Articles

Involvement of Lipid Raft Domain Signaling in Ex Vivo Maintenance of Hematopoietic Progenitor Cells.

Louisa Wirthlin, BA, Todd E. Meyerrose, BS, Michael H. Creer, MD, Jan A. Nolta, PhD

Blood (2005) 106 (11): 4216.

https://doi.org/10.1182/blood.V106.11.4216.4216

Published: 2005

Journal Articles

Bone Marrow-Derived Aldehyde Dehdrogenase Expressing Cells Possess Endothelial Progenitor Function in Addition to Hematopoietic Repopulating Ability and Aid in Blood Flow Recovery after Acute Ischemic Injury.

Benjamin J. Capoccia, BSc, Louisa Wirthlin, BSc, Rebecca Shepherd, MD, Kevin O’Dell, Jan A. Nolta, PhD, Daniel C. Link, MD, David A. Hess, PhD

Blood (2005) 106 (11): 2663.

https://doi.org/10.1182/blood.V106.11.2663.2663

Published: 2005

Journal Articles

Transplanted Human Aldehyde Dehydrogenase Expressing Stem Cells Circulate and Engraft Nonhematopoietic Tissues.

David A. Hess, PhD, Louisa Wirthlin, BS, Timothy C. Craft, BS, Phillip E. Herrbrich, BS, Marie Roberts, BS, Michael H. Creer, MD, Mark S. Sands, PhD, Jan A. Nolta, PhD

Blood (2005) 106 (11): 1693.

https://doi.org/10.1182/blood.V106.11.1693.1693

Published: 2005

Journal Articles

Human CD34+Cells Mobilized by AMD3100 Demonstrate Enhanced NOD/SCID Repopulating Function Compared to CD34+ Cells Mobilized by Granulocyte Colony Stimulating Factor.

David A. Hess, PhD, Louisa Wirthlin, BA, Timothy P. Craft, BS, Jesper Bonde, PhD, Ryan W. Lahey, Sarah A. Hohm, BS, Phillip E. Herrbrich, BS, John F. DiPersio, MD, Steven M. Devine, MD, Jan A. Nolta, PhD

Blood (2005) 106 (11): 1962.

https://doi.org/10.1182/blood.V106.11.1962.1962

Published: 2005

Journal Articles

CD133-Expressing Cells with High Aldehyde Dehydrogenase Activity Represent a Primitive Human Hematopoietic Stem Cell Population with Enhanced Repopulating Potential.

David A. Hess, PhD, Louisa Wirthlin, BS, Timothy P. Craft, BS, Todd E. Meyerrose, BS, Jan A. Nolta, PhD

Blood (2004) 104 (11): 250.

https://doi.org/10.1182/blood.V104.11.250.250

Published: 2004

Journal Articles

Human CD34 + Cells Rapidly Mobilized by AMD3100 Repopulate NOD/SCID Mice with Equivalent Efficiency as CD34 + Cells Mobilized by G-CSF.

David A. Hess, PhD, Jesper Bonde, PhD, Timothy P. Craft, BS, Louisa Wirthlin, BS, John F. DiPersio, MD, PhD, Steven M. Devine, MD, Jan A. Nolta, PhD

Blood (2004) 104 (11): 1186.

https://doi.org/10.1182/blood.V104.11.1186.1186

Published: 2004

Journal Articles

Transplantation of Human Aldehyde Dehydrogenase Expressing Cells Leads to Widespread Tissue Distribution of Donor Cells in the Novel NOD/SCID/MPSVII Xenotransplantation Model.

David A. Hess, PhD, Timothy P. Craft, BS, Louisa Wirthlin, BS, Phillip E. Herrbrich, BS, A. Alex Hofling, PhD, Mark S. Sands, PhD, Jan A. Nolta, PhD

Blood (2004) 104 (11): 3601.

https://doi.org/10.1182/blood.V104.11.3601.3601

Published: 2004

Journal Articles

Isolation of Human CD34 - Cells with High Aldehyde Dehydrogenase Activity Reveals a Novel Population with Hematopoietic Repopulating Potential.

David A. Hess, PhD, Phillip E. Herrbrich, BS, Louisa Wirthlin, BS, Timothy P. Craft, BS, Jan A. Nolta, PhD

Blood (2004) 104 (11): 3214.

https://doi.org/10.1182/blood.V104.11.3214.3214

Published: 2004

Journal Articles

Functional characterization of highly purified human hematopoietic repopulating cells isolated according to aldehyde dehydrogenase activity

David A. Hess, Todd E. Meyerrose, Louisa Wirthlin, Timothy P. Craft, Phillip E. Herrbrich, Michael H. Creer, Jan A. Nolta

Blood (2004) 104 (6): 1648–1655.

https://doi.org/10.1182/blood-2004-02-0448

Published: 2004

NARROW

Initial Results of a First-in-Human, Phase I Study Point-of-Care Manufacturing of Trispecific CAR-T Cells Targeting CD19/20/22 in B-Cell Malignancies

Evaluating the Safety and Efficacy of Anti-HIV Transgenic Cells in a Humanized Mouse Model (NOD/SCIDγ c −/− ) for HIV Stem Cell Gene Therapy.

In Vivo Biosafety Model To Assess Risk of Adverse Events from Retroviral and Lentiviral Vectors.

Adult Human Stem Cells Exert Therapeutic Effects To Repair Damaged Tissues in Xenograft Systems through Secretion of Trophic Factors Rather Than Direct Incorporation and Expansion.

Selection based on CD133 and high aldehyde dehydrogenase activity isolates long-term reconstituting human hematopoietic stem cells

Involvement of Lipid Raft Domain Signaling in Ex Vivo Maintenance of Hematopoietic Progenitor Cells.

Bone Marrow-Derived Aldehyde Dehdrogenase Expressing Cells Possess Endothelial Progenitor Function in Addition to Hematopoietic Repopulating Ability and Aid in Blood Flow Recovery after Acute Ischemic Injury.

Transplanted Human Aldehyde Dehydrogenase Expressing Stem Cells Circulate and Engraft Nonhematopoietic Tissues.

Human CD34+Cells Mobilized by AMD3100 Demonstrate Enhanced NOD/SCID Repopulating Function Compared to CD34+ Cells Mobilized by Granulocyte Colony Stimulating Factor.

CD133-Expressing Cells with High Aldehyde Dehydrogenase Activity Represent a Primitive Human Hematopoietic Stem Cell Population with Enhanced Repopulating Potential.

Human CD34 + Cells Rapidly Mobilized by AMD3100 Repopulate NOD/SCID Mice with Equivalent Efficiency as CD34 + Cells Mobilized by G-CSF.

Transplantation of Human Aldehyde Dehydrogenase Expressing Cells Leads to Widespread Tissue Distribution of Donor Cells in the Novel NOD/SCID/MPSVII Xenotransplantation Model.

Isolation of Human CD34 - Cells with High Aldehyde Dehydrogenase Activity Reveals a Novel Population with Hematopoietic Repopulating Potential.

Functional characterization of highly purified human hematopoietic repopulating cells isolated according to aldehyde dehydrogenase activity

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American Society of Hematology

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American Society of Hematology

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