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Virginia Goettl
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Journal Articles

The Multi-CDK Inhibitor Dinaciclib Shows Synergistic Activity with the BET Inhibitor PLX51107 and Reverses BET Resistance through Inhibition of Canonical Wnt Signaling in Acute Myeloid Leukemia (AML)

Alexander Marr, Soumendrakrishna Karmahapatra, Dominique Corbin, Yerdanos Asemelash, Steven Sher, Shaneice Renee Mitchell, Bonnie K Harrington, Shelley Orwick, Larry Beaver, Ronni Wasmuth, Virginia Goettl, Alice S. Mims, Karilyn T. Larkin, Sumithira Vasu, Meixiao Long, James S. Blachly, Ramiro Garzon, John C. Byrd, Rosa Lapalombella, Nicole Grieselhuber
Journal: Blood
Blood (2022) 140 (Supplement 1): 3075–3076.
https://doi.org/10.1182/blood-2022-160277
Published: 2022
Journal Articles

NAMPT Inhibitor KPT-9274 Selectively Targets Self-Renewal Capacity in Acute Myeloid Leukemia

Shaneice Renee Mitchell, BS, Nicole Grieselhuber, MD PhD, Yerdanos Asemelash, Matthew Cannon, BA, Shelley Orwick, BS, Pratibha Sharma, PhD, Virginia Goettl, DVM, PhD, Vinay K Puduvalli, MD MBBS, Deepa Sampath, PhD, Alice S. Mims, MD, James S. Blachly, MD, Amy M. Lehman, PhD, Bonnie K. Harrington, DVM, Justin Breitbach, Erkan Baloglu, William Senapedis, PhD, Rosa Lapalombella, PhD, John C. Byrd, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3931.
https://doi.org/10.1182/blood-2018-99-119358
Published: 2018
Journal Articles

Selective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemia

Rosa Lapalombella, Qingxiang Sun, Katie Williams, Larissa Tangeman, Shruti Jha, Yiming Zhong, Virginia Goettl, Emilia Mahoney, Caroline Berglund, Sneha Gupta, Alicia Farmer, Rajeswaran Mani, Amy J. Johnson, David Lucas, Xiaokui Mo, Dirk Daelemans, Vincent Sandanayaka, Sharon Shechter, Dilara McCauley, Sharon Shacham, Michael Kauffman, Yuh Min Chook, John C. Byrd
Journal: Blood
Blood (2012) 120 (23): 4621–4634.
https://doi.org/10.1182/blood-2012-05-429506
Published: 2012
Includes: Supplemental data
Journal Articles

Significant in Vivo Efficacy of the SINE KPT-330 in Mouse Models of CLL.

Rosa Lapalombella, PhD, Virginia Goettl, Katie Williams, Larissa Tangeman, Shruti Jha, Jason A Dubovsky, Ph.D, Danielle L Chappell, Amy J Johnson, PhD, Vincent Sandanayaka, Sharon Shechter, Dilara McCauley, PhD, Sharon Shacham, PhD MBA, Michael Kauffman, MD, PhD, John C. Byrd, MD
Journal: Blood
Blood (2012) 120 (21): 2452.
https://doi.org/10.1182/blood.V120.21.2452.2452
Published: 2012
Journal Articles

Global Inhibition of Bruton's Tyrosine Kinase (BTK) Delays the Development and Expansion of Chronic Lymphocytic Leukemia (CLL) in the TCL1 Mouse Model of Disease

Jennifer A. Woyach, MD, Matthew R Stefanovski, B.S., Virginia Goettl, Amy S. Ruppert, MAS, Kelly A Smucker, Lisa L. Smith, Jason A Dubovsky, Ph.D, William H. Towns, Jessica MacMurray, Melanie E. Davis, Yicheng Mao, Betty Y. Chang, PhD, Joseph J. Buggy, PhD, John C. Byrd, MD, Amy J Johnson, PhD
Journal: Blood
Blood (2012) 120 (21): 183.
https://doi.org/10.1182/blood.V120.21.183.183
Published: 2012