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Journal Articles

Long term outcomes of ET and PV patients after clinical trial treatment with interferon alfa

Megan Metzger, Heidi Kosiorek, Ashley Yu, Veer Shah, Nooshin Beygui, Marina Kremyanskaya, Amylou Dueck, Ronald Hoffman, John Mascarenhas

Blood (2025) 146 (Supplement 1): 7345.

https://doi.org/10.1182/blood-2025-7345

Published: 2025

Journal Articles

A phase 2 study of canakinumab in patient with myelofibrosis: Results from part 1

Andrew Kuykendall, Rupali Roy, Abdulraheem Yacoub, Marina Kremyanskaya, Aaron Gerds, Ronald Paquette, Jeanne Palmer, Kathryn Johnson, Heidi Kosiorek, Amylou Dueck, Carolyn Mead-Harvey, Ashley Yu, Rami Komrokji, Raajit Rampal, Ruben Mesa, Ronald Hoffman, John Mascarenhas

Blood (2025) 146 (Supplement 1): 483.

https://doi.org/10.1182/blood-2025-483

Published: 2025

Journal Articles

Bone marrow adipocytes (BMA) as a novel biomarker of molecular response in patients with essential thrombocythemia (ET) and polycythemia vera (PV) treated with pegylated interferon alfa-2A

John Mascarenhas, Justin Johnson, Heidi Kosiorek, Megan Metzger, Tiziano Barbui, Josef Prchal, Alessandro Rambaldi, Abdulraheem Yacoub, Ashley Yu, Ruben Mesa, Marina Kremyanskaya, Amylou Dueck, Ronald Hoffman, Mohamed Salama

Blood (2025) 146 (Supplement 1): 5590.

https://doi.org/10.1182/blood-2025-5590

Published: 2025

Journal Articles

Phase II study of reparixin in patients with myelofibrosis. myeloproliferative neoplasms research consortium (MPN-RC) 120 trial

Marina Kremyanskaya, Aaron Gerds, Rupali Bhave, Andrew Kuykendall, Eunice Wang, Heidi Kosiorek, Amylou Dueck, Carolyn Mead-Harvey, Kathryn Johnson, Ashley Yu, Anna Rita Migliaccio, Ruben Mesa, Ronald Hoffman, John Mascarenhas

Blood (2025) 146 (Supplement 1): 3829.

https://doi.org/10.1182/blood-2025-3829

Published: 2025

Journal Articles

Predictors of symptom improvement in myeloproliferative neoplasms: A real-world retrospective cohort study

Muhammad Ali Khan, Muhammad Uzair Sarfraz, Muhammad Hussnain Sadiq, Fouad Nahhat, Japneet Kaur Oberoi, John Camoriano, Cecilia Arana Yi, Jennifer Andres, Joshua Blocher, Heidi Kosiorek, Irbaz Riaz, Jeanne Palmer

Blood (2025) 146 (Supplement 1): 3823.

https://doi.org/10.1182/blood-2025-3823

Published: 2025

Journal Articles

Pegylated interferon alfa-2a for polycythemia vera or essential thrombocythemia resistant or intolerant to hydroxyurea

Blood (2019) 134 (18): 1498–1509.

https://doi.org/10.1182/blood.2019000428

Published: 2019

Includes: Supplemental data

Journal Articles

Oral idasanutlin in patients with polycythemia vera

John Mascarenhas, Min Lu, Heidi Kosiorek, Elizabeth Virtgaym, Lijuan Xia, Lonette Sandy, Ruben Mesa, Bruce Petersen, Noushin Farnoud, Vesna Najfeld, Raajit Rampal, Amylou Dueck, Ronald Hoffman

Blood (2019) 134 (6): 525–533.

https://doi.org/10.1182/blood.2018893545

Published: 2019

Includes: Supplemental data

Journal Articles

SETBP1 and NRAS Mutations Are Frequent Events in Post-Myeloproliferative Neoplasm Acute Myeloid Leukemia (post-MPN AML) Lacking JAK-STAT Activating Mutations

Blood (2017) 130 (Supplement 1): 203.

https://doi.org/10.1182/blood.V130.Suppl_1.203.203

Published: 2017

Journal Articles

Myeloproliferative Neoplasms and Depressive Symptoms, Diagnosis, and Associations

Leslie Padrnos, MD, Robyn M. Scherber, MD, Blake T. Langlais, Amylou Dueck, PhD, Jennifer Huberty, PhD, Holly L. Geyer, MD, Krisstina L. Gowin, DO, Heidi Kosiorek, MS, Marlene Bruso, MS, Zhenya Senyak, MA, Matthew M Clark, PhD, Michael Boxer, MD, Mary Cotter, MA, Claire N. Harrison, BMBCh, DM, FRCP, FRCPath, Ruben A Mesa, MD

Blood (2017) 130 (Supplement 1): 2161.

https://doi.org/10.1182/blood.V130.Suppl_1.2161.2161

Published: 2017

Journal Articles

Duration Matters: Impact of Time from Diagnosis on Symptoms in Patients with Hematologic Malignancies

Leslie Padrnos, MD, Heidi Kosiorek, MS, Robert M Bennett, III, Amylou Constance Dueck, PhD, Krisstina L. Gowin, DO, Robyn M. Scherber, MD, Holly L. Geyer, MD, Jeanne Palmer, MD, Donald Northfelt, MD, Joseph R Mikhael, MD FRCPC, MD, Nandita Khera, MD, Ruben A Mesa, MD

Blood (2017) 130 (Supplement 1): 2162.

https://doi.org/10.1182/blood.V130.Suppl_1.2162.2162

Published: 2017

Journal Articles

Advanced Forms of the Myeloproliferative Neoplasms Are Associated with Chromosomal Abnormalities Involving 1q and 12q: Implicating MDM2 and MDM4 in Disease Progression

Bridget Marcellino, MD PhD, Joseph Tripodi, Min Lu, PhDMD, Heidi Kosiorek, MS, John Mascarenhas, MD, Raajit K. Rampal, MD PhD, Amylou Constance Dueck, PhD, Ronald Hoffman, MD, Vesna Najfeld, PhD

Blood (2017) 130 (Supplement 1): 204.

https://doi.org/10.1182/blood.V130.Suppl_1.204.204

Published: 2017

Journal Articles

Quality of Life and Symptom Burden Among Patients with Myeloproliferative Neoplasms: Do Symptoms Impact Quality of Life?

Blake T. Langlais, Heidi Kosiorek, MS, Holly Geyer, MD, Robyn M. Scherber, MD, Ruben A Mesa, MD, Amylou C. Dueck, PhD

Blood (2017) 130 (Supplement 1): 3453.

https://doi.org/10.1182/blood.V130.Suppl_1.3453.3453

Published: 2017

Journal Articles

A Pilot Study of Online Yoga to Improve Fatigue and Quality of Life in Myeloproliferative Neoplasm Patients

Ryan Eckert, MS, Jennifer Huberty, PhD, Amylou Dueck, PhD, Heidi Kosiorek, MS, Linda Larkey, PhD, Ruben A Mesa, MD

Blood (2017) 130 (Supplement 1): 3443.

https://doi.org/10.1182/blood.V130.Suppl_1.3443.3443

Published: 2017

Journal Articles

Open Label Phase I Study of Single Agent Oral RG7388 (idasanutlin) in Patients with Polycythemia Vera and Essential Thrombocythemia

John Mascarenhas, MD, Min Lu, PhDMD, Elizabeth Virtgaym, Heidi Kosiorek, MS, Marina Stal, Lonette Sandy, Alicia Orellana, MD MPH, Lijuan Xia, Marina Kremyanskaya, MD PhD, Bruce Petersen, MD, Amylou Dueck, PhD, Ronald Hoffman, MD

Blood (2017) 130 (Supplement 1): 254.

https://doi.org/10.1182/blood.V130.Suppl_1.254.254

Published: 2017

Journal Articles

Transfusion Dependence at Day +100 Predicts Poorer Outcomes in Patients Undergoing Allogeneic Stem Cell Transplantation for Myelofibrosis

Tania Jain, MD, Katie L. Kunze, PhD, Daniel K. Partain, MD, Heidi Kosiorek, MS, Vivek Roy, MD, Nandita Khera, MD, James L. Slack, MD, Mrinal M. Patnaik, MDMBBS, William J. Hogan, MBBCh, Pierre Noel, MD, Veena D. S. Fauble, MD, Jose F. Leis, MD PhD, Lisa Sproat, MD MSW, Ruben A Mesa, MD, Jeanne Palmer, MD

Blood (2017) 130 (Supplement 1): 4561.

https://doi.org/10.1182/blood.V130.Suppl_1.4561.4561

Published: 2017

Journal Articles

Myelodysplastic Syndromes and Acute Myelogenous Leukemia Resulting from Therapy for Autoimmune Disease, a Case-Control Cohort Study

Natalie Ertz-Archambault, MD, Heidi Kosiorek, M.S., Janna Castro, Gretchen Taylor, MD, Robert Marino, Amylou Constance Dueck, PhD, Aref Al-Kali, MD, Susanne Gauthier, R.N., Laura E. Finn, MD, James M. Foran, MD, Lisa Sproat, MD MSW, Raoul Tibes, MD PhD

Blood (2015) 126 (23): 5636.

https://doi.org/10.1182/blood.V126.23.5636.5636

Published: 2015

Journal Articles

Symptom Burden Profile in Myelofibrosis Patients with Thrombocytopenia: Lessons and Unmet Needs

Holly Geyer, MD, Robyn M Scherber, MD MPH, Heidi Kosiorek, Amylou C. Dueck, PhD, Jean-Jacques Kiladjian, MD PhD, Zhijian Xiao, MD, Stefanie Slot, Sonja Zweegman, MD PhD, Federico Sackmann, Ana Kerguelen Fuentes, Dolores Hernandez-Maraver, PhD, Konstanze Dohner, MD, Claire N. Harrison, Deepti Radia, Pablo J. Muxi, MD, Carlos Besses, Francisco Cervantes, Peter L. Johansson, MD PhD, Bjorn Andreasson, MDPhD, Alessandro Rambaldi, MD, Tiziano Barbui, MD, Karin Bonatz, Andreas Reiter, MD, Francoise Boyer, MD, Gabriel Etienne, MD PhD, Jean-Christophe Ianotto, MD, Dana Ranta, Lydia Roy, MD, Jean-Yves Cahn, Norman I Maldonado, MD, Giovanni Barosi, Maria Ferrari, Robert Peter Gale, MD PhD DSc, Gunnar Birgegard, MD PhD, Zefeng Xu, MD, Yue Zhang, MD, Xiujuan Sun, MD, Junqing Xu, Peihong Zhang, Peter te Boekhorst, Suzan Commandeur, Harry C. Schouten, MD PhD, Heike L Pahl, PhD, Martin Griesshammer, MD, Frank Stegelmann, MD, Thomas Lehmann, Alessandro M. Vannucchi, Francesco Passamonti, MD, Jan Samuelsson, MD PhD, Ruben A. Mesa, MD

Blood (2015) 126 (23): 4080.

https://doi.org/10.1182/blood.V126.23.4080.4080

Published: 2015

Journal Articles

Living with Cancer: An Educational Intervention in Cancer Patients Can Improve Knowledge Deficit

Leslie Padrnos, MD, Joseph Mikhael, MD, Robert Bennett, Heidi Kosiorek, Amylou Constance Dueck, PhD, Donald W. Northfelt, MD, Raoul Tibes, MD PhD, Nandita Khera, MD, Ruben A. Mesa, MD

Blood (2015) 126 (23): 3321.

https://doi.org/10.1182/blood.V126.23.3321.3321

Published: 2015

Journal Articles

Unmet Needs for Symptom Control in Essential Thrombocythemia with Front Line Therapy

Holly Geyer, MD, Robyn M. Scherber, MD MPH, Heidi Kosiorek, M.S., Amylou C. Dueck, PhD, Jean-Jacques Kiladjian, MD PhD, Stefanie Slot, Zhijian Xiao, DO, Sonja Zweegman, MD PhD, Federico Sackmann, Ana Kerguelen Fuentes, Dolores Hernandez-Maraver, PhD, Konstanze Döhner, MD, Claire N. Harrison, Deepti Radia, Pablo J. Muxi, MD, Carlos Besses, Francisco Cervantes, Peter L. Johansson, MD PhD, Bjorn Andreasson, MDPhD, Alessandro Rambaldi, MD, Tiziano Barbui, MD, Karin Bonatz, Andreas Reiter, MD, Francoise Boyer, MD, Gabriel Etienne, MD PhD, Jean-Christophe Ianotto, MD, Dana Ranta, Lydia Roy, MD, Jean-Yves Cahn, Norman I Maldonado, MD, Giovanni Barosi, MD, Maria Ferrari, Robert Peter Gale, MD PhD DSc, Gunnar Birgegard, MD PhD, Zefeng Xu, MD, Yu Zhang, B.S., Xiujuan Sun, MD, Junqing Xu, Peihong Zhang, Peter A. te Boekhorst, Suzan Commandeur, Harry C. Schouten, MD PhD, Heike L Pahl, PhD, Martin Griesshammer, MD, Frank Stegelmann, MD, Thomas Lehmann, Alessandro M. Vannucchi, MD, Francesco Passamonti, MD, Jan Samuelsson, MD PhD, Ruben A. Mesa, MD

Blood (2015) 126 (23): 5175.

https://doi.org/10.1182/blood.V126.23.5175.5175

Published: 2015

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Long term outcomes of ET and PV patients after clinical trial treatment with interferon alfa

A phase 2 study of canakinumab in patient with myelofibrosis: Results from part 1

Bone marrow adipocytes (BMA) as a novel biomarker of molecular response in patients with essential thrombocythemia (ET) and polycythemia vera (PV) treated with pegylated interferon alfa-2A

Phase II study of reparixin in patients with myelofibrosis. myeloproliferative neoplasms research consortium (MPN-RC) 120 trial

Predictors of symptom improvement in myeloproliferative neoplasms: A real-world retrospective cohort study

Pegylated interferon alfa-2a for polycythemia vera or essential thrombocythemia resistant or intolerant to hydroxyurea

Oral idasanutlin in patients with polycythemia vera

SETBP1 and NRAS Mutations Are Frequent Events in Post-Myeloproliferative Neoplasm Acute Myeloid Leukemia (post-MPN AML) Lacking JAK-STAT Activating Mutations

Myeloproliferative Neoplasms and Depressive Symptoms, Diagnosis, and Associations

Duration Matters: Impact of Time from Diagnosis on Symptoms in Patients with Hematologic Malignancies

Advanced Forms of the Myeloproliferative Neoplasms Are Associated with Chromosomal Abnormalities Involving 1q and 12q: Implicating MDM2 and MDM4 in Disease Progression

Quality of Life and Symptom Burden Among Patients with Myeloproliferative Neoplasms: Do Symptoms Impact Quality of Life?

A Pilot Study of Online Yoga to Improve Fatigue and Quality of Life in Myeloproliferative Neoplasm Patients

Open Label Phase I Study of Single Agent Oral RG7388 (idasanutlin) in Patients with Polycythemia Vera and Essential Thrombocythemia

Transfusion Dependence at Day +100 Predicts Poorer Outcomes in Patients Undergoing Allogeneic Stem Cell Transplantation for Myelofibrosis

Myelodysplastic Syndromes and Acute Myelogenous Leukemia Resulting from Therapy for Autoimmune Disease, a Case-Control Cohort Study

Symptom Burden Profile in Myelofibrosis Patients with Thrombocytopenia: Lessons and Unmet Needs

Living with Cancer: An Educational Intervention in Cancer Patients Can Improve Knowledge Deficit

Unmet Needs for Symptom Control in Essential Thrombocythemia with Front Line Therapy

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