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Journal Articles

In Vivo panCAR-Mediated Depletion of B Cells in Non-Human Primates Using a Circular (oRNA®) Anti-CD20 CAR

Juliet Crabtree, Akinola Emmanuel, Ganapathy Subramanian Sankaran, Jui Dutta-Simmons, Karolina Kosakowska, Tracy Dimezzo, Ian Langer, Prapti Vyas, David Soto, Akshi Thakkar, Grace Chen, Maja Sedic, Scott Barros, Allen Horhota, Isin Dalkilic-Liddle, LT Thiruneelakantapillai, Muthusamy Jayaraman, Megan Hoban, Frank Neumann, Robert Mabry
Journal: Blood
Blood (2024) 144 (Supplement 1): 3427.
https://doi.org/10.1182/blood-2024-210256
Published: 2024
Journal Articles

The Absence of NLRP6 in Donor T Cells Exacerbates Gvhd

Masahiro Suto, Eri Matsuki, Masahiro Miyata, Erika Sekiguchi, Hiroya Tamaki, Isao Tawara, Daniel Peltier, Grace Chen, Kenichi Ishizawa, Pavan Reddy, Tomomi Toubai
Journal: Blood
Blood (2021) 138 (Supplement 1): 2766.
https://doi.org/10.1182/blood-2021-152089
Published: 2021
Journal Articles

NLRP6 in Donor T Cells Separately Regulates CD4 and CD8 Mediated Graft-Versus-Host Disease in Experimental Murine BMT

Masahiro Suto, Eri Matsuki, MD, Erika Sekiguchi, Hiroya Tamaki, MD PhD, Isao Tawara, MD PhD, Grace Chen, MD PhD, Kenichi Ishizawa, MD PhD, Pavan Reddy, Tomomi Toubai
Journal: Blood
Blood (2019) 134 (Supplement_1): 1926.
https://doi.org/10.1182/blood-2019-123875
Published: 2019
Journal Articles

Targeting Neutrophil Aging and the Microbiota for the Treatment of Sickle Cell Disease

Dachuan Zhang, MS, Grace Chen, PhD, Deepa Manwani, MD, Arthur Mortha, PhD, Chunliang Xu, PhD, Jeremiah J. Faith, PhD, Robert D. Burk, MD, Yuya Kunisaki, MD PhD, Jung-Eun Jang, PhD, Christoph Scheiermann, PhD, Miriam Merad, MD PhD, Paul S. Frenette, MD
Journal: Blood
Blood (2015) 126 (23): 279.
https://doi.org/10.1182/blood.V126.23.279.279
Published: 2015
Journal Articles

NLRP6 in Host Target Tissues Exacerbates Graft-Versus-Host Disease

Tomomi Toubai, MD PhD, Corinne Rossi, MD, Hiroya Tamaki, MD PhD, Nathan Mathewson, PhD, Katherine Oravecz-Wilson, MS, Cynthia Zajac, BS, Chen Liu, MD PhD, Stuart Brabbs, Yaping Sun, MD PhD, Grace Chen, MD PhD, Pavan Reddy, MD
Journal: Blood
Blood (2015) 126 (23): 148.
https://doi.org/10.1182/blood.V126.23.148.148
Published: 2015
Journal Articles

Vaso-Occlusion-Promoting Neutrophil Mac-1 Integrin Activation in Human Sickle Cell Crises Is Stabilized By a Single Dose of Intravenous Gammaglobulin

Deepa Manwani, MD, Grace Chen, PhD, Veronica Carullo, MD, Hillel W Cohen, DrPH, MPH, Stelian Serban, Olugbenga Olowukere, Jungeun Jang, Matthew Huggins, Henny H Billett, MD, George F. Atweh, MD, Paul S. Frenette, MD, Patricia A Shi, MD
Journal: Blood
Blood (2014) 124 (21): 4089.
https://doi.org/10.1182/blood.V124.21.4089.4089
Published: 2014
Journal Articles

NLRP6 Expression By the Hosts Enhances the Severity of Experimental Graft-Versus-Host Disease (GVHD)

Tomomi Toubai, MD PhD, Hiroya Tamaki, MD PhD, Corinne Rossi, MD, Katherine Oravecz-Wilson, PhD, Chen Liu, MD, PhD, Nathan Mathewson, BSPS, Yaping Sun, MD PhD MS, Grace Chen, MD, Pavan Reddy, MD
Journal: Blood
Blood (2014) 124 (21): 2421.
https://doi.org/10.1182/blood.V124.21.2421.2421
Published: 2014
Journal Articles

Heme-induced neutrophil extracellular traps contribute to the pathogenesis of sickle cell disease

Grace Chen, Dachuan Zhang, Tobias A. Fuchs, Deepa Manwani, Denisa D. Wagner, Paul S. Frenette
Journal: Blood
Blood (2014) 123 (24): 3818–3827.
https://doi.org/10.1182/blood-2013-10-529982
Published: 2014
Includes: Supplemental data
Journal Articles

Heme-Induced Neutrophil Extracellular Traps (NETs) Formation Contributes To Sickle Cell Disease Pathogenesis

Grace Chen, PhD, Tobias A. Fuchs, PhD, Denisa D. Wagner, PhD, Paul S. Frenette, MD
Journal: Blood
Blood (2013) 122 (21): 184.
https://doi.org/10.1182/blood.V122.21.184.184
Published: 2013