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Journal Articles

Ruxolitinib REACHes FOR children with GVHD

Tomomi Toubai

Blood (2024) 144 (20): 2069–2070.

https://doi.org/10.1182/blood.2024026120

Published: 2024

Journal Articles

A Phase 1 Trial of OPB-111077 in Combination with Bendamustine (B) and Rituximab (R) in Patients with Relapsed or Refractory (R/R) Diffuse Large B-Cell Lymphoma (DLBCL): Preliminary Results of Dose-Escalation Stage

Tomomi Toubai, Junya Kuroda, Youko Suehiro, Yuko Mishima, Kazutaka Sunami, Koji Kato, Nobuhiko Uoshima, Takahiro Kumode, Ai Ota, Kaori Mitsuki, Daisuke Yokota, Yuri Sano, Yasuhito Terui

Blood (2023) 142 (Supplement 1): 4464.

https://doi.org/10.1182/blood-2023-179716

Published: 2023

Journal Articles

Allogeneic Donor T Cells Directly Attack Renal Endothelial and Epithelial Cells in Mice

Masahiro Miyata, Eri Matsuki, Yuka Hosokawa, Masahiro Suto, Kazunobu Ichikawa, Dan Peltier, Kenichi Ishizawa, Masafumi Watanabe, Tomomi Toubai

Blood (2022) 140 (Supplement 1): 7332–7333.

https://doi.org/10.1182/blood-2022-158676

Published: 2022

Journal Articles

Interim PET-Guided ABVD or ABVD/Escalated BEACOPP for Newly Diagnosed Advanced-Stage Classic Hodgkin Lymphoma (JCOG1305, INNOVATE-HL study)

Blood (2022) 140 (Supplement 1): 3718–3720.

https://doi.org/10.1182/blood-2022-157006

Published: 2022

Journal Articles

GPR109A in GVHD: friend or foe?

Tomomi Toubai

Blood (2022) 139 (15): 2271–2272.

https://doi.org/10.1182/blood.2021014128

Published: 2022

Journal Articles

The Absence of NLRP6 in Donor T Cells Exacerbates Gvhd

Masahiro Suto, Eri Matsuki, Masahiro Miyata, Erika Sekiguchi, Hiroya Tamaki, Isao Tawara, Daniel Peltier, Grace Chen, Kenichi Ishizawa, Pavan Reddy, Tomomi Toubai

Blood (2021) 138 (Supplement 1): 2766.

https://doi.org/10.1182/blood-2021-152089

Published: 2021

Journal Articles

Immunopathology and biology-based treatment of steroid-refractory graft-versus-host disease

Tomomi Toubai, John Magenau

Blood (2020) 136 (4): 429–440.

https://doi.org/10.1182/blood.2019000953

Published: 2020

Journal Articles

NLRP6 in Donor T Cells Separately Regulates CD4 and CD8 Mediated Graft-Versus-Host Disease in Experimental Murine BMT

Masahiro Suto, Eri Matsuki, MD, Erika Sekiguchi, Hiroya Tamaki, MD PhD, Isao Tawara, MD PhD, Grace Chen, MD PhD, Kenichi Ishizawa, MD PhD, Pavan Reddy, Tomomi Toubai

Blood (2019) 134 (Supplement_1): 1926.

https://doi.org/10.1182/blood-2019-123875

Published: 2019

Journal Articles

Donor T Cell Independent Mechanism Is Critical for Mediating Steroid Refractory Gvhd in Murine Models

Tomomi Toubai, MDPhD, Corrine Rossi, Isao Tawara, MD PhD, Chen Liu, MD PhD, Cynthia Zajac, Katherine Oravecz-Wilson, BS, MS, Dan Peltier, MD, Yaping Sun, MD PhD MS, Hideaki Fujiwara, MD, Mary Mansour Riwes, DO, Israel Henig, MD, Stephanie Kim, BS, Masahiro Suto, Kenichi Ishizawa, MD PhD, Pavan Reddy, MD

Blood (2018) 132 (Supplement 1): 4529.

https://doi.org/10.1182/blood-2018-99-114634

Published: 2018

Journal Articles

Metabolic Reprogramming of Dendritic Cells Is Controlled By the Mir-142

Yaping Sun, MD PhD MS, Thomas Saunders, PhD, Katherine Oravecz-Wilson, BS, MS, Sydney Bridges, BS, Richard McEachin, PhD, Julia Wu, PhD, Stephanie Kim, Cynthia Zajac, Tomomi Toubai, MDPhD, Hideaki Fujiwara, Israel Henig, MD, Dan Peltier, MD, Pavan Reddy, MD

Blood (2017) 130 (Supplement 1): 2265.

https://doi.org/10.1182/blood.V130.Suppl_1.2265.2265

Published: 2017

Journal Articles

Microbial Metabolite Sensor GPCR43 Controls Severity of Experimental Gvhd

Hideaki Fujiwara, MD PhD, Nathan Mathewson, PhD, Tomomi Toubai, MD PhD, Katherine Oravecz-Wilson, MS, Cynthia Zajac, BS, Julia Wu, BS, Yaping Sun, MD PhD, Chen Liu, MD PhD, Pavan R. Reddy, MD

Blood (2016) 128 (22): 1157.

https://doi.org/10.1182/blood.V128.22.1157.1157

Published: 2016

Journal Articles

IAPs Protect Host Target Tissues from Graft-Versus-Host Disease (GVHD)

Tomomi Toubai, MD PhD, Corinne Rossi, MD, Katherine Oravecz-Wilson, MS, Cynthia Zajac, BS, Hideaki Fujiwawa, MD PhD, Stuart Brabbs, Julia Wu, BS, Yaping Sun, MD PhD, John M. Magenau, MD, Pavan R. Reddy, MD

Blood (2016) 128 (22): 810.

https://doi.org/10.1182/blood.V128.22.810.810

Published: 2016

Journal Articles

Donor T Cells Intrinsic Responses to Damps Regulated By Siglec-G-CD24 Axis Mitigate Gvhd but Maintain GVL in Experimental BMT Model

Tomomi Toubai, MD PhD, Corinne Rossi, MD, Katherine Oravecz-Wilson, MS, Nathan Mathewson, PhD, Cynthia Zajac, BS, Chen Liu, MD PhD, Stuart Brabbs, Bailey Redman, BS, Hiroya Tamaki, MD PhD, Julia Wu, BS, Yaping Sun, MD PhD, Pang Zheng, MD PhD, Yang Liu, PhD, Pavan Reddy, MD

Blood (2015) 126 (23): 229.

https://doi.org/10.1182/blood.V126.23.229.229

Published: 2015

Journal Articles

Genome-Wide Binding Studies of Acetyl-STAT3 Demonstrates a Novel Regulatory Pathway in Dendritic Cells

Yaping Sun, MD PhD, Matthew Iyer, MD PhD, Meng Zhao, PhD, Richard McEachin, PhD, Yi-Mi Wu, PhD, Xuhong Cao, MS, Katherine Oravecz-Wilson, MS, Cynthia Zajac, BS, Nathan Mathewson, PhD, Julia Wu, BS, Corinne Rossi, MD, Tomomi Toubai, MD, PhD, Zhaohui Qin, PhD, Arul Chinnaiyan, Pavan Reddy, MD

Blood (2015) 126 (23): 647.

https://doi.org/10.1182/blood.V126.23.647.647

Published: 2015

Journal Articles

NLRP6 in Host Target Tissues Exacerbates Graft-Versus-Host Disease

Tomomi Toubai, MD PhD, Corinne Rossi, MD, Hiroya Tamaki, MD PhD, Nathan Mathewson, PhD, Katherine Oravecz-Wilson, MS, Cynthia Zajac, BS, Chen Liu, MD PhD, Stuart Brabbs, Yaping Sun, MD PhD, Grace Chen, MD PhD, Pavan Reddy, MD

Blood (2015) 126 (23): 148.

https://doi.org/10.1182/blood.V126.23.148.148

Published: 2015

Journal Articles

ATG5 Dependent Autophagy Uncouples T Cell Functions and Modulates Experimental Graft-Versus-Host Disease

Katherine Oravecz-Wilson, MS, Corinne Rossi, MD, Chen Liu, MD PhD, Tomomi Toubai, MD PhD, Hiroya Tamaki, MD PhD, Cynthia Zajac, BS, Stuart Brabbs, Nathan Mathewson, PhD, Julia Wu, BS, Yaping Sun, MD PhD, Pavan Reddy, MD

Blood (2015) 126 (23): 149.

https://doi.org/10.1182/blood.V126.23.149.149

Published: 2015

Journal Articles

BET bromodomain inhibition suppresses graft-versus-host disease after allogeneic bone marrow transplantation in mice

Yaping Sun, Ying Wang, Tomomi Toubai, Katherine Oravecz-Wilson, Chen Liu, Nathan Mathewson, Julia Wu, Corinne Rossi, Emily Cummings, Depei Wu, Shaomeng Wang, Pavan Reddy

Blood (2015) 125 (17): 2724–2728.

https://doi.org/10.1182/blood-2014-08-598037

Published: 2015

Journal Articles

NLRP6 Expression By the Hosts Enhances the Severity of Experimental Graft-Versus-Host Disease (GVHD)

Tomomi Toubai, MD PhD, Hiroya Tamaki, MD PhD, Corinne Rossi, MD, Katherine Oravecz-Wilson, PhD, Chen Liu, MD, PhD, Nathan Mathewson, BSPS, Yaping Sun, MD PhD MS, Grace Chen, MD, Pavan Reddy, MD

Blood (2014) 124 (21): 2421.

https://doi.org/10.1182/blood.V124.21.2421.2421

Published: 2014

Journal Articles

Unbiased Metabolic Profiling Uncovers a Crucial Role for the Microbial Metabolite Butyrate in Modulating GI Epithelial Cell Damage from Gvhd

Nathan Mathewson, BSPS, Anna Mathew, MBBS, Katherine Oravecz-Wilson, PhD, Julia Wu, BS, Tomomi Toubai, MD, Corinne Rossi, MD, Yaping Sun, MD PhD MS, Subramaniam Pennathur, MBBS, Pavan Reddy, MD

Blood (2014) 124 (21): 536.

https://doi.org/10.1182/blood.V124.21.536.536

Published: 2014

Journal Articles

Siglec-G–CD24 axis controls the severity of graft-versus-host disease in mice

Tomomi Toubai, Guoqing Hou, Nathan Mathewson, Chen Liu, Ying Wang, Katherine Oravecz-Wilson, Emily Cummings, Corinne Rossi, Rebecca Evers, Yaping Sun, Julia Wu, Sung Won Choi, Dexing Fang, Pan Zheng, Yang Liu, Pavan Reddy

Blood (2014) 123 (22): 3512–3523.

https://doi.org/10.1182/blood-2013-12-545335

Published: 2014

Includes: Supplemental data

NARROW

Ruxolitinib REACHes FOR children with GVHD

A Phase 1 Trial of OPB-111077 in Combination with Bendamustine (B) and Rituximab (R) in Patients with Relapsed or Refractory (R/R) Diffuse Large B-Cell Lymphoma (DLBCL): Preliminary Results of Dose-Escalation Stage

Allogeneic Donor T Cells Directly Attack Renal Endothelial and Epithelial Cells in Mice

Interim PET-Guided ABVD or ABVD/Escalated BEACOPP for Newly Diagnosed Advanced-Stage Classic Hodgkin Lymphoma (JCOG1305, INNOVATE-HL study)

GPR109A in GVHD: friend or foe?

The Absence of NLRP6 in Donor T Cells Exacerbates Gvhd

Immunopathology and biology-based treatment of steroid-refractory graft-versus-host disease

NLRP6 in Donor T Cells Separately Regulates CD4 and CD8 Mediated Graft-Versus-Host Disease in Experimental Murine BMT

Donor T Cell Independent Mechanism Is Critical for Mediating Steroid Refractory Gvhd in Murine Models

Metabolic Reprogramming of Dendritic Cells Is Controlled By the Mir-142

Microbial Metabolite Sensor GPCR43 Controls Severity of Experimental Gvhd

IAPs Protect Host Target Tissues from Graft-Versus-Host Disease (GVHD)

Donor T Cells Intrinsic Responses to Damps Regulated By Siglec-G-CD24 Axis Mitigate Gvhd but Maintain GVL in Experimental BMT Model

Genome-Wide Binding Studies of Acetyl-STAT3 Demonstrates a Novel Regulatory Pathway in Dendritic Cells

NLRP6 in Host Target Tissues Exacerbates Graft-Versus-Host Disease

ATG5 Dependent Autophagy Uncouples T Cell Functions and Modulates Experimental Graft-Versus-Host Disease

BET bromodomain inhibition suppresses graft-versus-host disease after allogeneic bone marrow transplantation in mice

NLRP6 Expression By the Hosts Enhances the Severity of Experimental Graft-Versus-Host Disease (GVHD)

Unbiased Metabolic Profiling Uncovers a Crucial Role for the Microbial Metabolite Butyrate in Modulating GI Epithelial Cell Damage from Gvhd

Siglec-G–CD24 axis controls the severity of graft-versus-host disease in mice

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American Society of Hematology

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American Society of Hematology

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