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Journal Articles

NLRP6 regulates ZAP-70-erk signaling in both murine and human T cells and influences acute graft-versus-host disease(GVHD)

Free
Eri Matsuki, Masahiro Miyata, Jana Gawron, Masahiro Suto, Hiroya Tamaki, Hideaki Fujiwara, Yuki Ishizawa, Erika Sekiguchi, Tayu Tobai, Sae Ushio, Katherine Oravecz-Wilson, Grace Chen, Isao Tawara, Kazunobu Ichikawa, Masafumi Watanabe, Kenichi Ishizawa, Hisayuki Yokoyama, Dan Peltier, Bruce Blazar, Robert Zeiser, Pavan Reddy, Tomomi Toubai
Journal: Blood
Blood (2025) 146 (Supplement 1): 4090.
https://doi.org/10.1182/blood-2025-4090
Published: 2025
Journal Articles

Longitudinal and integrated analysis of oral and stool microbiome in allogeneic hematopoietic cell transplantation recipients.

Free
Ronald Siebenaler, E. Anders Kiledal, Marcus Geer, John Magenau, Attaphol Pawarode, Sarah Anand, Monalisa Ghosh, John Maciejewski, Darren King, Sung Choi, Gregory Yanik, Pavan Reddy, Mary Riwes
Journal: Blood
Blood (2025) 146 (Supplement 1): 4225.
https://doi.org/10.1182/blood-2025-4225
Published: 2025
Journal Articles

Vorinostat for GVHD prophylaxis in children, adolescents, and young adults (AYA) shows low incidence of acute GVHD and relapse with encouraging overall survival after allogeneic hematopoietic cell transplantation (HCT): A multisite, nonrandomized clinical trial

Free
Nicolas Parnell, Kristen Votruba, Xiao Cao, Thomas Braun, Tracey Churay, Michelle Rozwadowski, Erik Winnega, Mark Vander Lugt, Gregory Yanik, Ghada Abusin, John Magenau, Mary Riwes, Vanessa Fabrizio, Carrie Kitko, April Rahrig, Jodi Skiles, Julie-An Talano, Kirsten Williams, Pavan Reddy, Sung Won Choi
Journal: Blood
Blood (2025) 146 (Supplement 1): 2451.
https://doi.org/10.1182/blood-2025-2451
Published: 2025
Journal Articles

Regulatory long noncoding RNA of T cells (ReLoT/LINC00402) impairs Rorγt+ allogeneic T cells

Free
Van Anh Do-Thi, Emma Bratch, Jathniel Hernandez, Dani Jade-Alice Bastaic, George Sandusky, Pavan Reddy, Dan Peltier
Journal: Blood
Blood (2025) 146 (Supplement 1): 161.
https://doi.org/10.1182/blood-2025-161
Published: 2025
Journal Articles

Inflammatory memory of stem cells: implications for hematologic diseases

Available to Purchase
Dongchang Zhao, Pavan Reddy
Journal: Blood
Blood (2025) 146 (11): 1265–1275.
https://doi.org/10.1182/blood.2024028197
Published: 2025
Journal Articles

Novel regulators of GVHD revealed through microbiome and metabolome patterns across distinct intestinal regions

Available to Purchase
Emma Lauder, Erik Anders Kiledal, Laure Maneix, Teal Furnholm, Ana Santibanez, Dongchang Zhao, Yaping Sun, Gregory J. Dick, Pavan Reddy
Journal: Blood
Blood (2025) 145 (23): 2774–2787.
https://doi.org/10.1182/blood.2024025924
Published: 2025
Includes: Supplemental data
Journal Articles

Oral inflammation and microbiome dysbiosis exacerbate chronic graft-versus-host disease

Open Access
CME
Yui Kambara, Hideaki Fujiwara, Akira Yamamoto, Kazuyoshi Gotoh, Shuma Tsuji, Mari Kunihiro, Tadashi Oyama, Toshiki Terao, Ayame Sato, Takehiro Tanaka, Daniel Peltier, Keisuke Seike, Hisakazu Nishimori, Noboru Asada, Daisuke Ennishi, Keiko Fujii, Nobuharu Fujii, Ken-ichi Matsuoka, Yoshihiko Soga, Pavan Reddy, Yoshinobu Maeda
Journal: Blood
Blood (2025) 145 (8): 881–896.
https://doi.org/10.1182/blood.2024024540
Published: 2025
Includes: Supplemental data
Journal Articles

A phase 2 trial of CD24Fc for prevention of graft-versus-host disease

Free
Clinical Trials & Observations
John Magenau, Samantha Jaglowski, Joseph Uberti, Sherif S. Farag, Mary Mansour Riwes, Attaphol Pawarode, Sarah Anand, Monalisa Ghosh, John Maciejewski, Thomas Braun, Martin Devenport, Susan Lu, Bhramori Banerjee, Carolyn DaSilva, Steven Devine, Mei-Jie Zhang, Linda J. Burns, Yang Liu, Pan Zheng, Pavan Reddy
Journal: Blood
Blood (2024) 143 (1): 21–31.
https://doi.org/10.1182/blood.2023020250
Published: 2024
Includes: Supplemental data
Journal Articles

Intestinal Geographical Pattern of Gut Microbiome and Metabolites Identifies Novel Regulators of Graft-Versus-Host Disease

Free
Emma Lauder, Anders Kiledal, Dongchang Zhao, Gregory Dick, Pavan Reddy
Journal: Blood
Blood (2023) 142 (Supplement 1): 2043.
https://doi.org/10.1182/blood-2023-191108
Published: 2023
Journal Articles

Absence of MHC Class I Expression on Target Cells Exacerbates Iron Dependent CD4+ T Cell Mediated Killing

Free
Emma Lauder, Dongchang Zhao, Lu Li, Yaping Sun, Katherine Oravecz-Wilson, Laure Maneix, Ana Santibanez, Pavan Reddy
Journal: Blood
Blood (2023) 142 (Supplement 1): 3843.
https://doi.org/10.1182/blood-2023-191033
Published: 2023
Journal Articles

Rational Modification of Human Gut Microbiome and Metabolites By Dietary Resistant Starch in Allogeneic Hematopoietic Stem Cell Transplantation: A Feasibility Study

Free
Mary Mansour Riwes, Jonathan Louis Golob, John M. Magenau, Costas Lyssiotis, Mengrou Shan, Gregory Dick, Thomas Braun, Thomas M Schmidt, Attaphol Pawarode, Sarah Anand, Monalisa Ghosh, John Maciejewski, Darren King, Sung W. Choi, Gregory Yanik, Marcus Johannes Geer, Ethan Hillman, Muneesh Tewari, Pavan Reddy
Journal: Blood
Blood (2023) 142 (Supplement 1): 2190.
https://doi.org/10.1182/blood-2023-181260
Published: 2023
Journal Articles

Inflammatory Memory Restrains Intestinal Stem Cell (ISC) Regeneration after Allogeneic Stem Cell Transplantation (SCT)

Free
Dongchang Zhao, Visweswaran Ravikumar, Emma Lauder, Lu Li, Yaping Sun, Katherine Oravecz-Wilson, Michael Brooks, Evan Keller, Fengju Chen, Laure Maneix, Ana Santibanez, Chad Creighton, Arvind Rao, Pavan Reddy
Journal: Blood
Blood (2023) 142 (Supplement 1): 347.
https://doi.org/10.1182/blood-2023-187189
Published: 2023
Journal Articles

The Absence of NLRP6 in Donor T Cells Exacerbates Gvhd

Free
Masahiro Suto, Eri Matsuki, Masahiro Miyata, Erika Sekiguchi, Hiroya Tamaki, Isao Tawara, Daniel Peltier, Grace Chen, Kenichi Ishizawa, Pavan Reddy, Tomomi Toubai
Journal: Blood
Blood (2021) 138 (Supplement 1): 2766.
https://doi.org/10.1182/blood-2021-152089
Published: 2021
Journal Articles

NLRP6 in Donor T Cells Separately Regulates CD4 and CD8 Mediated Graft-Versus-Host Disease in Experimental Murine BMT

Free
Masahiro Suto, Eri Matsuki, MD, Erika Sekiguchi, Hiroya Tamaki, MD PhD, Isao Tawara, MD PhD, Grace Chen, MD PhD, Kenichi Ishizawa, MD PhD, Pavan Reddy, Tomomi Toubai
Journal: Blood
Blood (2019) 134 (Supplement_1): 1926.
https://doi.org/10.1182/blood-2019-123875
Published: 2019
Journal Articles

Rational Modification of Intestinal Microbiome and Metabolites after Allogeneic Hematopoietic Stem Cell Transplantation with Resistant Starch: A Pilot Study

Free
Mary Mansour Riwes, DO, Alexander Schmidt, Thomas Braun, John M. Magenau, MD, Attaphol Pawarode, Brian Parkin, Sarah Anand, MD, Monalisa Ghosh, John Maciejewski, Darren King, Muneesh Tewari, Sung W. Choi, Gregory A. Yanik, Kristi Maccready, Thomas Schmidt, Pavan Reddy
Journal: Blood
Blood (2019) 134 (Supplement_1): 3276.
https://doi.org/10.1182/blood-2019-131216
Published: 2019
Journal Articles

Mitochondrial Complex II in Intestinal Epithelial Cells Is a Critical Metabolic Checkpoint That Regulates Severity of Gastrointestinal Graft-Versus-Host Disease

Free
Hideaki Fujiwara, Anna V Mathew, Ilya Kovalenko, Pal Anupama, Dan Peltier, Stephanie Kim, Austin Taylor, BA, Katherine Oravecz-Wilson, Yaping Sun, Costas Lyssiotis, Alnawaz Rehemtulla, Subramanian Pennarthur, Pavan Reddy
Journal: Blood
Blood (2019) 134 (Supplement_1): 584.
https://doi.org/10.1182/blood-2019-126775
Published: 2019
Journal Articles

ATG5 Dependent Autophagy in Graft-Versus-Host Disease Target Organs Mitigates Disease Severity Post Allogeneic Bone Marrow Transplant

Free
Austin Taylor, BA, Kay Oravecz-Wilson, Hideaki Fujiwara, Stephanie Kim, Dan Peltier, Molly Radosevich, Yaping Sun, Pavan Reddy
Journal: Blood
Blood (2019) 134 (Supplement_1): 1914.
https://doi.org/10.1182/blood-2019-131879
Published: 2019
Journal Articles

The MAGIC Algorithm Probability (MAP): A Novel Laboratory Biomarker for the Response to Treatment of Acute Graft-Versus-Host Disease

Free
Hrishikesh Srinagesh, BA, Umut Ozbek, PhD, Urvi Kapoor, MD, Francis Ayuketang Ayuk, MD, Mina D. Aziz, MD, Kaitlyn Ben-David, Hannah K. Choe, MD, Zachariah Defilipp, MD, Aaron Etra, MD, Stephan Grupp, MD PhD, Matthew Hartwell, MD, Elizabeth O. Hexner, MDMS, William J Hogan, MB, BCh, Carrie Kitko, MD, Steven Kowalyk, Jung-Yi Lin, MS, Hannah Major-Monfried, MD MSCR, Stephan Mielke, MD, Pietro Merli, MD, George Morales, Rainer Ordemann, MD, Michael A. Pulsipher, MD, Muna Qayed, MD MSc, Pavan Reddy, Ran Reshef, MD MSc, Wolf Roesler, MD, Karamjeet S. Sandhu, MD, Tal Schechter-Finkelstein, MD, Jay Shah, MD, Keith Sigel, MD PhD, Daniela Weber, MD, Matthias Wölfl, MD, Kitsada Wudhikarn, MD, Rachel Young, John E. Levine, MDMS, James L. M. Ferrara, MDDSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 367.
https://doi.org/10.1182/blood-2019-122011
Published: 2019
Journal Articles

Targeting Sec23b in COPII Vesicles Regulates T Cell Immunity

Free
Stephanie Kim, BS, Rami Khoriaty, MD, Rajesh Valanparambil, PhD, Julia Wu, PhD, Austin Taylor, BS, Hideaki Fujiwara, MD, Dan Peltier, MD, Yaping Sun, MD PhD MS, Israel Henig, MD, Cynthia Zajac, Katherine Oravecz-Wilson, BS, MS, Stuart Brabbs, Rafi Ahmed, PhD, David Ginsburg, MD, Pavan Reddy, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 859.
https://doi.org/10.1182/blood-2018-99-111628
Published: 2018
Journal Articles

RNA-Seq of Human T Cells after BMT Identifies Linc00402 As a Novel Regulator of Human T Cell Alloimmunity

Free
Dan Peltier, MD, Nicolas Robine, Guoqing Hou, PhD, Pavan Reddy, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4517.
https://doi.org/10.1182/blood-2018-99-113017
Published: 2018