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Isao Tawara
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Journal Articles

Treatment and Outcomes of Stage I-II Pulmonary MALT Lymphoma: A Multi-Institutional Observational Study in Japan

Kazutaka Suzuki, Kana Miyazaki, Naoko Asano, Hiroyuki Takahashi, Nobuhiro Hiramoto, Hiro Tatetsu, Ilseung Choi, Hiroshi Arima, Toshiki Uchida, Dai Maruyama, Takeharu Kato, Junji Hiraga, Nobuhiro Kanemura, Tohru Murayama, Shingo Yano, Shunsuke Ito, Naoki Takahashi, Shinsuke Iida, Tetsu Kobayashi, Motoshi Takao, Isao Tawara, Motoko Yamaguchi
Journal: Blood
Blood (2024) 144 (Supplement 1): 3030.
https://doi.org/10.1182/blood-2024-198992
Published: 2024
Journal Articles

Number of Sites of Involvement Predicts Central Nervous System Relapse in Patients with Localized Extranodal Natural Killer/T-Cell Lymphoma

Yuma Nato, Kana Miyazaki, Ayumi Fujimoto, Senzo Taguchi, Naoko Asano, Jun Amaki, Wataru Munakata, Yuko Shirouchi, Nobuko Kubota, Takeshi Maeda, Jun Takizawa, Kimikazu Yakushijin, Rika Sakai, Hideyuki Nakazawa, Masahiro Takeuchi, Noriko Fukuhara, Yuri Miyazawa, Ryoji Tokiya, Tohru Murayama, Isao Tawara, Yasuo Ejima, Ritsuro Suzuki, Motoko Yamaguchi
Journal: Blood
Blood (2024) 144 (Supplement 1): 3058.
https://doi.org/10.1182/blood-2024-198371
Published: 2024
Journal Articles

A JAK2 Germline Variant Modulates Cytokine Release from Stromal Niche Cells and Induces Remodeling of the Bone Marrow Niche

Komei Nishimura, Yuka Sugimoto, Keiki Nagaharu, Ryoichi Ono, Takuya Tsuji, Akihide Nakamura, Eiko Ohya, Isao Tawara, Tetsuya Nosaka, Kohshi Ohishi
Journal: Blood
Blood (2024) 144 (Supplement 1): 4523.
https://doi.org/10.1182/blood-2024-193876
Published: 2024
Journal Articles

A Simple Diagnostic Algorithm for the Prediction of JAK2 Mutation Status in Erythrocytosis Based on Complete Blood Count Data: A Multi-Center Retrospective Analysis

Keiko Maeyama, Yuka Sugimoto, Keiki Nagaharu, Eiko Oya, Eri Miyata, Atsushi Fujieda, Hiroyuki Miyashita, Takao Sekine, Shigehisa Tamaki, Kohshi Ohishi, Isao Tawara
Journal: Blood
Blood (2024) 144 (Supplement 1): 1789.
https://doi.org/10.1182/blood-2024-199350
Published: 2024
Journal Articles

Thrombotic and Bleeding Events in Japanese Adolescent and Young Adult PV and ET: Results from Japanese Multicenter Retrospective Study

Yuka Sugimoto, Keiki Nagaharu, Eiko Oya, Kohshi Ohishi, Isao Tawara, Tomoki Ito, Akihiko Gotoh, Mika Nakamae, Fumihiko Kimura, Michiaki Koike, Keita Kirito, Hideho Wada, Kensuke Usuki, Takayuki Tanaka, Takehiko Mori, Satoshi Wakita, Toshiki I Saito, Akiko Kada, Akiko M Saito, Kazuya Shimoda, Toshio Kurokawa, Akihiro Tomita, Yoko Edahiro, Yoshinori Hashimoto, Hitoshi Kiyoi, Koichi Akashi, Itaru Matsumura, Katsuto Takenaka, Norio Komatsu
Journal: Blood
Blood (2023) 142 (Supplement 1): 1831.
https://doi.org/10.1182/blood-2023-180561
Published: 2023
Journal Articles

Survival and CNS Relapse in Patients with CD5-Positive Diffuse Large B-Cell Lymphoma: A Multi-Institutional Observational Study in Japan

Yuma Nato, Kana Miyazaki, Dai Maruyama, Hiroyuki Takahashi, Kazutaka Sunami, Satsuki Murakami, Eiju Negoro, Yuri Miyazawa, Ilseung Choi, Takahiro Okada, Nobuyuki Takayama, Naoto Tomita, Shuji Momose, Yuto Kaneda, Masahiro Yoshida, Hiroshi Gomyo, Kohtaro Toyama, Momoko Nishikori, Akio Saito, Junji Hiraga, Taro Masunari, Naoki Takahashi, Junya Makiyama, Tomotaka Suzuki, Hiroko Tsunemine, Jun Takizawa, Takeharu Kato, Yasufumi Masaki, Noriko Fukuhara, Masataka Okamoto, Isao Tawara, Naoko Asano, Koichi Ohshima, Koji Izutsu, Koji Kato, Ritsuro Suzuki, Motoko Yamaguchi
Journal: Blood
Blood (2023) 142 (Supplement 1): 1762.
https://doi.org/10.1182/blood-2023-174647
Published: 2023
Journal Articles

Unveiling Highly Fluctuating Single-Cell Transcriptome Dynamics at a Novel Bifurcation Point in a Human Lymphoid Pathway

Keiki Nagaharu, Yasuhiro Kojima, Yuki Kageyama, Yuka Sugimoto, Masahiro Masuya, Shigeru Nii, Masahide Seki, Yutaka Suzuki, Isao Tawara, Teppei Shimamura, Naoyuki Katayama, Kohshi Ohishi
Journal: Blood
Blood (2022) 140 (Supplement 1): 5721–5722.
https://doi.org/10.1182/blood-2022-156157
Published: 2022
Journal Articles

The Absence of NLRP6 in Donor T Cells Exacerbates Gvhd

Masahiro Suto, Eri Matsuki, Masahiro Miyata, Erika Sekiguchi, Hiroya Tamaki, Isao Tawara, Daniel Peltier, Grace Chen, Kenichi Ishizawa, Pavan Reddy, Tomomi Toubai
Journal: Blood
Blood (2021) 138 (Supplement 1): 2766.
https://doi.org/10.1182/blood-2021-152089
Published: 2021
Journal Articles

Gene Polymorphisms and Vincristine-Induced Neuropathy in Patients Who Received R-CHOP Chemotherapy

Akihiko Sawaki, MD, Kana Miyazaki, MD PhD, Toshifumi Takeuchi, MD PhD, Kyoko Kobayashi, MD PhD, Hiroshi Imai, MD PhD, Isao Tawara, MD PhD, Ryoichi Ono, MD PhD, Tetsuya Nosaka, MD PhD, Motoko Yamaguchi, MD PhD, Naoyuki Katayama, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1624.
https://doi.org/10.1182/blood-2019-122796
Published: 2019
Journal Articles

NLRP6 in Donor T Cells Separately Regulates CD4 and CD8 Mediated Graft-Versus-Host Disease in Experimental Murine BMT

Masahiro Suto, Eri Matsuki, MD, Erika Sekiguchi, Hiroya Tamaki, MD PhD, Isao Tawara, MD PhD, Grace Chen, MD PhD, Kenichi Ishizawa, MD PhD, Pavan Reddy, Tomomi Toubai
Journal: Blood
Blood (2019) 134 (Supplement_1): 1926.
https://doi.org/10.1182/blood-2019-123875
Published: 2019
Journal Articles

Novel Cellular Immunotherapy Using Allogeneic Vγ9/δ2-T Cells Gene-Modified to Express HTLV-1 P40Tax-Specific TCR for the Treatment of Adult T Cell Leukemia

Hiroshi Fujiwara, MD PhD, Satoshi Okumura, Yoshihiro Miyahara, Linan Wan, Isao Tawara, MD PhD, Tatsuro Jo, MD PhD, Yuetsu Tanaka, PhD, Yoshimasa Tanaka, PhD, Hiroaki Ikeda, Hiroshi Shiku
Journal: Blood
Blood (2019) 134 (Supplement_1): 3216.
https://doi.org/10.1182/blood-2019-122412
Published: 2019
Journal Articles

A population of CD20 + CD27 + CD43 + CD38 lo/int B1 cells in PNH are missing GPI-anchored proteins and harbor PIGA mutations

Yuki Kageyama, Hiroshi Miwa, Isao Tawara, Kohshi Ohishi, Masahiro Masuya, Naoyuki Katayama
Journal: Blood
Blood (2019) 134 (1): 89–92.
https://doi.org/10.1182/blood.2019001343
Published: 2019
Includes: Supplemental data
Journal Articles

Donor T Cell Independent Mechanism Is Critical for Mediating Steroid Refractory Gvhd in Murine Models

Tomomi Toubai, MDPhD, Corrine Rossi, Isao Tawara, MD PhD, Chen Liu, MD PhD, Cynthia Zajac, Katherine Oravecz-Wilson, BS, MS, Dan Peltier, MD, Yaping Sun, MD PhD MS, Hideaki Fujiwara, MD, Mary Mansour Riwes, DO, Israel Henig, MD, Stephanie Kim, BS, Masahiro Suto, Kenichi Ishizawa, MD PhD, Pavan Reddy, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4529.
https://doi.org/10.1182/blood-2018-99-114634
Published: 2018
Journal Articles

CCR2 + Monocyte-Derived Ly6C - F4/80 + Fibrocytes Inhibit Collagen Degradation and Contribute to the Development of Colon Fibrosis Via Production of TIMP-1

Masahiro Masuya, MD PhD, Naoki Kuroda, MD, Kensuke Hachiya, MD, Isao Tawara, MD PhD, Yuki Kageyama, MD, Kohshi Ohishi, MD PhD, Hiroshi Miwa, MD PhD, Naoyuki Katayama, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3682.
https://doi.org/10.1182/blood-2018-99-118140
Published: 2018
Journal Articles

Safety and persistence of WT1-specific T-cell receptor gene−transduced lymphocytes in patients with AML and MDS

Clinical Trials & Observations
Isao Tawara, Shinichi Kageyama, Yoshihiro Miyahara, Hiroshi Fujiwara, Tetsuya Nishida, Yoshiki Akatsuka, Hiroaki Ikeda, Kazushi Tanimoto, Seitaro Terakura, Makoto Murata, Yoko Inaguma, Masahiro Masuya, Naoki Inoue, Tomohide Kidokoro, Sachiko Okamoto, Daisuke Tomura, Hideto Chono, Ikuei Nukaya, Junichi Mineno, Tomoki Naoe, Nobuhiko Emi, Masaki Yasukawa, Naoyuki Katayama, Hiroshi Shiku
Journal: Blood
Blood (2017) 130 (18): 1985–1994.
https://doi.org/10.1182/blood-2017-06-791202
Published: 2017
Includes: Supplemental data
Journal Articles

Phase 1 Clinical Trial of Adoptive Immunotherapy for Acute Myelogenous Leukemia and Myelodysplastic Syndrome, Using Gene-Modified Autologous Lymphocytes Expressing WT1-Specific T-Cell Receptor

Kazushi Tanimoto, MD PhD, Hiroshi Fujiwara, MD PhD, Isao Tawara, MD PhD, Masahiro Masuya, MD PhD, Shinichi Kageyama, MD PhD, Tetsuya Nishida, MD PhD, Makoto Murata, MD PhD, Seitaro Terakura, MD PhD, Yoshiki Akatsuka, MD PhD, Hiroaki Ikeda, MD PhD, Yoshihiro Miyahara, MD PhD, Ikuei Nukaya, PhD, Kazutoh Takesako, PhD, Nobuhiko Emi, MD PhD, Naoyuki Katayama, MD PhD, Hiroshi Shiku, MD PhD, Masaki Yasukawa, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1653.
https://doi.org/10.1182/blood.V128.22.1653.1653
Published: 2016
Journal Articles

MYD88, CD79B, and CD79A Gene Mutations in CD5-Positive Diffuse Large B-Cell Lymphoma

Toshifumi Takeuchi, MD, Motoko Yamaguchi, MD PhD, Kyoko Kobayashi, MD PhD, Kana Miyazaki, MD PhD, Hiroshi Imai, MD PhD, Ryoichi Ono, MD PhD, Isao Tawara, MD PhD, Tetsuya Nosaka, MD PhD, Kyosuke Tanaka, MD PhD, Naoyuki Katayama, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1861.
https://doi.org/10.1182/blood.V128.22.1861.1861
Published: 2016
Journal Articles

Tumor-Specific Donor Lymphocyte Infusion for Tumor Relapse after MHC-Haploidentical Hematopoietic Stem Cell Transplantation

Isao Tawara, MD PhD, Kana Okamori, MS, Naoyuki Katayama, MD PhD, Hiroshi Shiku, MD PhD, Hiroaki Ikeda, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2157.
https://doi.org/10.1182/blood.V128.22.2157.2157
Published: 2016
Journal Articles

Adoptive Transfer of WT1-Specific TCR Gene-Transduced Lymphocytes in Patients with Myelodysplastic Syndrome and Acute Myeloid Leukemia

Isao Tawara, MD PhD, Masahiro Masuya, MD PhD, Shinichi Kageyama, MD PhD, Tetsuya Nishida, MD PhD, Seitaro Terakura, MD PhD, Makoto Murata, MD PhD, Hiroshi Fujiwara, MD PhD, Yoshiki Akatsuka, MD PhD, Hiroaki Ikeda, MD PhD, Yoshihiro Miyahara, MD PhD, Daisuke Tomura, PhD, Ikuei Nukaya, PhD, Kazutoh Takesako, PhD, Nobuhiko Emi, MDPhD, Masaki Yasukawa, MD PhD, Naoyuki Katayama, MD PhD, Hiroshi Shiku, MD PhD
Journal: Blood
Blood (2015) 126 (23): 97.
https://doi.org/10.1182/blood.V126.23.97.97
Published: 2015
Journal Articles

Histone deacetylase inhibition regulates inflammation and enhances Tregs after allogeneic hematopoietic cell transplantation in humans

Brief Report
Sung Won Choi, Erin Gatza, Guoqing Hou, Yaping Sun, Joel Whitfield, Yeohan Song, Katherine Oravecz-Wilson, Isao Tawara, Charles A. Dinarello, Pavan Reddy
Journal: Blood
Blood (2015) 125 (5): 815–819.
https://doi.org/10.1182/blood-2014-10-605238
Published: 2015
Includes: Supplemental data