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Journal Articles

Ongoing Spontaneous DNA Damage and the Role of Aberrant Epigenome in Multiple Myeloma

Maria Gkotzamanidou, MD PhD, Masood Shammas, PhD, Vassilis L. Souliotis, Weihua Song, MD, Jagannath Pal, MBBS, PhD, Puru Nanjappa, MS, Naim Rashid, PhD, Kenneth C. Anderson, MD, Meletios A. Dimopoulos, MD, James Bradner, MD, Nikhil C. Munshi, MD

Blood (2014) 124 (21): 3398.

https://doi.org/10.1182/blood.V124.21.3398.3398

Published: 2014

Journal Articles

Dysregulation of SHFM1, a Novel Target for Prevention of Genomic Instability in Myeloma, Is Associated with Epigenetic Changes at Specific CpG Sites

Masood Shammas, PhD, Subodh Kumar, PhD, Jagannath Pal, PhD, Puru Nanjappa, MS, Mehmat Samur, PhD, Maria Gkotzamanidou, MD PhD, Jialan Shi, MD PhD, Nikhil C. Munshi, MD

Blood (2014) 124 (21): 862.

https://doi.org/10.1182/blood.V124.21.862.862

Published: 2014

Journal Articles

Telomerase-Mediated Repair of Induced DNA Breaks Leads to Increased Genomic Instability in Multiple Myeloma Cells: Possible Mechanism and Translational Significance

Jagannath Pal, PhD, Masood Shammas, PhD, Subodh Kumar, PhD, Maria Gkotzamanidou, MD PhD, Puru Nanjappa, MS, Leutz Buon, Nikhil C. Munshi, MD

Blood (2014) 124 (21): 5170.

https://doi.org/10.1182/blood.V124.21.5170.5170

Published: 2014

Journal Articles

Elevated APE1 Mediates Dysregulation of Homologous Recombination in Myeloma: Mechanisms and Translational Significance

Subodh Kumar, PhD, Maria Gkotzamanidou, MD PhD, Jagannath Pal, PhD, Renquan Lu, MD PhD, Puru Nanjappa, MS, Jialan Shi, MD PhD, Masood Shammas, PhD, Nikhil C. Munshi, MD

Blood (2014) 124 (21): 2074.

https://doi.org/10.1182/blood.V124.21.2074.2074

Published: 2014

Journal Articles

Role Of Base Excision Repair Associated AP Nuclease Activity In The Induction Of Homologous Recombination Repair Pathway and Survival Of MM Cells Following DNA Damage

Subodh Kumar, PhD, Jagannath Pal, PhD, Jialan Shi, PhD, Puru Nanjappa, MS, Maria Gkotzamanidou, MD, Masood Shammas, PhD, Nikhil Munshi, MD

Blood (2013) 122 (21): 1248.

https://doi.org/10.1182/blood.V122.21.1248.1248

Published: 2013

Journal Articles

Spontaneous DNA Damage and Aberrant Epigenome In Multiple Myeloma Constitute The Path To Disease Genomic Instability

Maria Gkotzamanidou, MD, PhD, Masood A. Shammas, Vassilis L. Souliotis, Jagannath Pal, MD, Jun Qi, Ph.D., Andrew Brown, James E Bradner, MD, Kenneth C. Anderson, MD, Nikhil C. Munshi, MD

Blood (2013) 122 (21): 4884.

https://doi.org/10.1182/blood.V122.21.4884.4884

Published: 2013

Journal Articles

Telomerase Contributes To Repair Of DNA Breaks In Myeloma Cells By Incorporating “TTAGGG” Sequences Within Genome: Biological and Translational Significance

Jagannath Pal, PhD, Jie Ding, PhD, Subodh Kumar, PhD, Zachary Hunter, Teresa Calimeri, MD, Jianhong Lin, Maria Gkotzamanidou, MD, Giovanni Parmigiani, PhD, Steven Treon, Masood Shammas, PhD, Nikhil Munshi, MD

Blood (2013) 122 (21): 1249.

https://doi.org/10.1182/blood.V122.21.1249.1249

Published: 2013

Journal Articles

Direct Evidence and Functional Significance of DNA Repair by Telomerase in Multiple Myeloma

Jagannath Pal, Renquan Lu, Puru Nanjappa, Ms, Ankit V Vahia, PhD, Masood A Shammas, PhD, Nikhil C Munshi, MD

Blood (2012) 120 (21): 4416.

https://doi.org/10.1182/blood.V120.21.4416.4416

Published: 2012

Journal Articles

Aberrant Non-Homologous End Joining in Multiple Myeloma: A Role in Genomic Instability and As Potential Prognostic Marker.

Blood (2012) 120 (21): 2932.

https://doi.org/10.1182/blood.V120.21.2932.2932

Published: 2012

Journal Articles

Elevated APEX1 Endonuclease Is Associated with Increased DNA Breaks and Instability in Myeloma

Masood Shammas, Ph.D, Jagannath Pal, PhD, Ankit V Vahia, Ph.D, Puru Nanjappa, Ms, Manit N Munshi, Jialan Shi, MD, PhD, Nikhil C. Munshi, MD

Blood (2011) 118 (21): 1805.

https://doi.org/10.1182/blood.V118.21.1805.1805

Published: 2011

Journal Articles

A Novel Role of Telomerase in DNA Repair and Genome Maintenance in Myeloma.

Jagannath Pal, PhD, Puru Nanjappa, Ms, Ankit V Vahia, PhD, Jialan Shi, MD, PhD, Masood A Shammas, PhD, Nikhil C. Munshi, MD

Blood (2011) 118 (21): 628.

https://doi.org/10.1182/blood.V118.21.628.628

Published: 2011

Journal Articles

Whole Genome Sequencing Defines the Clonal Architecture and Genomic Evolution in Myeloma: Tumor Heterogeneity with Continued Acquisition of New Mutational Change

Nikhil C. Munshi, MD, Hervé Avet-Loiseau, MD, PhD, Philip J. Stephens, Graham R Bignell, Yu-Tzu Tai, PhD, Masood Shammas, Ph.D, Cheng Li, PhD, Parantu K Shah, PhD, Mariateresa Fulciniti, PhD, Jagannath Pal, PhD, Ankit V Vahia, Ph.D, Paul G. Richardson, MD, Stephane Minvielle, PhD, Peter Campbell, Kenneth C. Anderson, MD, Andrew Futreal

Blood (2011) 118 (21): 297.

https://doi.org/10.1182/blood.V118.21.297.297

Published: 2011

Journal Articles

Inhibition of Homologous Recombination Pathway Promotes Telomere Shortening and Cell Survival without Affecting Telomerase Activity In Myeloma

Jagannath Pal, Jason Wong, Puru Nanjappa, Saem Lee, B.A., Masood Shammas, Nikhil C. Munshi, MD

Blood (2010) 116 (21): 786.

https://doi.org/10.1182/blood.V116.21.786.786

Published: 2010

Journal Articles

Biology and Therapeutic Targeting of Sp1 Transactivation In Myeloma

Mariateresa Fulciniti, Samir B. Amin, MBBS, Puru Nanjappa, Scott J Rodig, Teru Hideshima, Jagannath Pal, Varuna Mohan, Keeyun Lee, Masood Shammas, Stephane Minvielle, Rao Prabhala, Hervé Avet-Loiseau, MD, PhD, Li Cheng, Kenneth C. Anderson, Nikhil C. Munshi, MD

Blood (2010) 116 (21): 134.

https://doi.org/10.1182/blood.V116.21.134.134

Published: 2010

Journal Articles

Elevated Homologous Recombination Induces Karyotypic Changes and Predicts Poor Clinical Outcome In Multiple Myeloma

Jagannath Pal, Jeffrey Sawyer, Samir B. Amin, MBBS, Cheng Li, Puru Nanjappa, Saem Lee, B.A., Stephane Minvielle, Hervé Avet-Loiseau, Masood Shammas, Nikhil C. Munshi

Blood (2010) 116 (21): 1924.

https://doi.org/10.1182/blood.V116.21.1924.1924

Published: 2010

Journal Articles

Significant Biological Role of Sp1 Transactivation in Myeloma: Potential Therapeutic Application.

Mariateresa Fulciniti, PhD, Teru Hideshima, M.D., Ph.D., Puru Nanjappa, MS, Scott Rodig, M.D., Ph.D., Samir B Amin, MBBS, Dheeraj Pelluru, PhD, Jagannath Pal, Rao Prabhala, PhD, Masood A Shammas, PhD, Pierfrancesco Tassone, Scott Mohrland, Kenneth C. Anderson, MD, Nikhil C. Munshi

Blood (2009) 114 (22): 1841.

https://doi.org/10.1182/blood.V114.22.1841.1841

Published: 2009

Journal Articles

Perturbation of Genomic Instability by Wortmannin in Myeloma.

Jagannath Pal, MBBS, PhD, Dheeraj Pelluru, PhD, Mariateresa Fulciniti, PhD, Samir B Amin, MBBS, Leutz Buon, PhD, Rao Prabhala, PhD, Kenneth C. Anderson, Masood A Shammas, PhD, Nikhil C. Munshi

Blood (2009) 114 (22): 1105.

https://doi.org/10.1182/blood.V114.22.1105.1105

Published: 2009

Journal Articles

Whole Genome Paired End Sequencing Identifies Genomic Evolution in Myeloma.

Nikhil C. Munshi, Herve Avet-Loiseau, MD, PhD, Phil Stephens, PhD, Masood A Shammas, PhD, Cheng Li, Ph.D, Leutz Buon, PhD, Samir B Amin, MBBS, Parantu Shah, PhD, Benjamin King, MD, Mariateresa Fulciniti, PhD, Jagannath Pal, MBBS, PhD, Yu-Tzu Tai, PhD, Paul Richardson, M.D., Ph.D., Stephane Minvielle, Ph.D, Peter Campbell, MD, Kenneth C. Anderson, MD, Andrew Futreal, PhD

Blood (2009) 114 (22): 2846.

https://doi.org/10.1182/blood.V114.22.2846.2846

Published: 2009

NARROW

Ongoing Spontaneous DNA Damage and the Role of Aberrant Epigenome in Multiple Myeloma

Dysregulation of SHFM1, a Novel Target for Prevention of Genomic Instability in Myeloma, Is Associated with Epigenetic Changes at Specific CpG Sites

Telomerase-Mediated Repair of Induced DNA Breaks Leads to Increased Genomic Instability in Multiple Myeloma Cells: Possible Mechanism and Translational Significance

Elevated APE1 Mediates Dysregulation of Homologous Recombination in Myeloma: Mechanisms and Translational Significance

Role Of Base Excision Repair Associated AP Nuclease Activity In The Induction Of Homologous Recombination Repair Pathway and Survival Of MM Cells Following DNA Damage

Spontaneous DNA Damage and Aberrant Epigenome In Multiple Myeloma Constitute The Path To Disease Genomic Instability

Telomerase Contributes To Repair Of DNA Breaks In Myeloma Cells By Incorporating “TTAGGG” Sequences Within Genome: Biological and Translational Significance

Direct Evidence and Functional Significance of DNA Repair by Telomerase in Multiple Myeloma

Aberrant Non-Homologous End Joining in Multiple Myeloma: A Role in Genomic Instability and As Potential Prognostic Marker.

Elevated APEX1 Endonuclease Is Associated with Increased DNA Breaks and Instability in Myeloma

A Novel Role of Telomerase in DNA Repair and Genome Maintenance in Myeloma.

Whole Genome Sequencing Defines the Clonal Architecture and Genomic Evolution in Myeloma: Tumor Heterogeneity with Continued Acquisition of New Mutational Change

Inhibition of Homologous Recombination Pathway Promotes Telomere Shortening and Cell Survival without Affecting Telomerase Activity In Myeloma

Biology and Therapeutic Targeting of Sp1 Transactivation In Myeloma

Elevated Homologous Recombination Induces Karyotypic Changes and Predicts Poor Clinical Outcome In Multiple Myeloma

Significant Biological Role of Sp1 Transactivation in Myeloma: Potential Therapeutic Application.

Perturbation of Genomic Instability by Wortmannin in Myeloma.

Whole Genome Paired End Sequencing Identifies Genomic Evolution in Myeloma.

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American Society of Hematology

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American Society of Hematology

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