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John H. van Duzer
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Journal Articles

Mechanistic Insights Into Fetal Hemoglobin (HbF) Induction Through Chemical Inhibition Of Histone Deacetylase 1 and 2 (HDAC1/2)

Jeffrey R Shearstone, PhD, John H van Duzer, PhD, Simon S Jones, PhD, Matthew Jarpe, PhD
Journal: Blood
Blood (2013) 122 (21): 2253.
https://doi.org/10.1182/blood.V122.21.2253.2253
Published: 2013
Journal Articles

Pharmacological Inhibition Of Histone Deacetylase (HDAC) 1, 2 Or 3 Have Distinct Effects On Cellular Viability, Erythroid Differentiation, and Fetal Globin (HbG) Induction

Jeffrey R Shearstone, PhD, John H van Duzer, PhD, Simon S Jones, PhD, Matthew Jarpe, PhD
Journal: Blood
Blood (2013) 122 (21): 564.
https://doi.org/10.1182/blood.V122.21.564.564
Published: 2013
Journal Articles

Induction of Human Fetal Hemoglobin Expression by Selective Inhibitors of Histone Deacetylase 1 and 2 (HDAC1/2)

Jeffrey R Shearstone, PhD, John H van Duzer, PhD, James E Bradner, MD, Ralph Mazitschek, PhD, Simon S Jones, Matthew Jarpe, PhD
Journal: Blood
Blood (2012) 120 (21): 3259.
https://doi.org/10.1182/blood.V120.21.3259.3259
Published: 2012
Journal Articles

Preclinical activity, pharmacodynamic, and pharmacokinetic properties of a selective HDAC6 inhibitor, ACY-1215, in combination with bortezomib in multiple myeloma

Loredana Santo, Teru Hideshima, Andrew L. Kung, Jen-Chieh Tseng, David Tamang, Min Yang, Matthew Jarpe, John H. van Duzer, Ralph Mazitschek, Walter C. Ogier, Diana Cirstea, Scott Rodig, Homare Eda, Tyler Scullen, Miriam Canavese, James Bradner, Kenneth C. Anderson, Simon S. Jones, Noopur Raje
Journal: Blood
Blood (2012) 119 (11): 2579–2589.
https://doi.org/10.1182/blood-2011-10-387365
Published: 2012
Includes: Supplemental data
Journal Articles

Selective HDAC6 Inhibition Via ACY-1215, Either Alone or in Combination with Bortezomib, Restores Osteoblast Function and Suppresses Osteoclast Differentiation in Multiple Myeloma

Loredana Santo, MD, Teru Hideshima, MD, PhD, Andrew L. Kung, MD, PhD, Jen-Chieh Tseng, PhD, David Tamang, PhD, Min Yang, PhD, Matthew Jarpe, PhD, John H. van Duzer, PhD, Ralph Mazitschek, PhD, Diana Cirstea, MD, Homare Eda, MD, PhD, Tyler A. Scullen, BA, Scott Rodig, MD, PhD, Miriam Canavese, PhD, James Bradner, MD, Kenneth C Anderson, MD, Simon Jones, PhD, Noopur S. Raje, MD
Journal: Blood
Blood (2011) 118 (21): 2908.
https://doi.org/10.1182/blood.V118.21.2908.2908
Published: 2011
Journal Articles

Pharmacodynamic and Pharmacokinetic Properties of a Novel and Selective HDAC6 Inhibitor, ACY-1215, in Combination with Bortezomib in Multiple Myeloma

Loredana Santo, MD, Teru Hideshima, MD, PhD, Andrew L. Kung, MD, PhD, Jen-Chieh Tseng, PhD, David Tamang, PhD, Min Yang, PhD, Matthew Jarpe, PhD, John H. van Duzer, PhD, Ralph Mazitschek, PhD, Walter C Ogier, Diana D. Cirstea, MD, Scott Rodig, MD, PhD, Homare Eda, MD, PhD, Tyler A. Scullen, BA, Miriam Canavese, PhD, James E. Bradner, MD, Kenneth C Anderson, MD, Simon Jones, PhD, Noopur S. Raje, MD
Journal: Blood
Blood (2011) 118 (21): 2912.
https://doi.org/10.1182/blood.V118.21.2912.2912
Published: 2011