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Journal Articles

Cebpβ/IL1/TNFα Positive Feedback Loop Drives Drug Resistance of BCL2 and MDM2 Inhibitors in Monocytic Leukemia Cells

Basil Allen, Daniel Bottomly, Anthony Wang, Thomas Koehnke, Lindsey Savoy, Peter Ryabini, Reid Chen, Kara Johnson, Stephen E. Kurtz, Anupriya Agarwal, Michelle Barton, Brian J. Druker, Ravi Majeti, Jeffrey W Tyner, Shannon K McWeeney, Haijiao Zhang
Journal: Blood
Blood (2023) 142 (Supplement 1): 2937.
https://doi.org/10.1182/blood-2023-178096
Published: 2023
Journal Articles

The sWT1+ - Transcript Confers Cytarabine Resistance Via Upregulation of HOXA3 and GATA2 Axis

Reid Chen, Daniel Bottomly, Lindsey Savoy, Peter Ryabinin, Schannon K Mcweeney, Haijiao Zhang
Journal: Blood
Blood (2022) 140 (Supplement 1): 11778.
https://doi.org/10.1182/blood-2022-159260
Published: 2022
Journal Articles

Characterize Biomarkers and Mechanisms of Resistance for MDM2 Inhibitors in AML

Lindsey Savoy, Daniel Bottomly, Reid Chen, Basil Allen, Jeffrey W. Tyner, Shannon K. McWeeney, Haijiao Zhang
Journal: Blood
Blood (2022) 140 (Supplement 1): 8778–8779.
https://doi.org/10.1182/blood-2022-157622
Published: 2022
Journal Articles

Genomic landscape of neutrophilic leukemias of ambiguous diagnosis

Haijiao Zhang, Beth Wilmot, Daniel Bottomly, Kim-Hien T. Dao, Emily Stevens, Christopher A. Eide, Vishesh Khanna, Angela Rofelty, Samantha Savage, Anna Reister Schultz, Nicola Long, Libbey White, Amy Carlos, Rachel Henson, Chenwei Lin, Robert Searles, Robert H. Collins, Daniel J. DeAngelo, Michael W. Deininger, Tamara Dunn, Than Hein, Marlise R. Luskin, Bruno C. Medeiros, Stephen T. Oh, Daniel A. Pollyea, David P. Steensma, Richard M. Stone, Brian J. Druker, Shannon K. McWeeney, Julia E. Maxson, Jason R. Gotlib, Jeffrey W. Tyner
Journal: Blood
Blood (2019) 134 (11): 867–879.
https://doi.org/10.1182/blood.2019000611
Published: 2019
Includes: Supplemental data
Journal Articles

Biomarkers Predicting Venetoclax Sensitivity and Strategies for Venetoclax Combination Treatment

Haijiao Zhang, Beth Wilmot, PhD, Daniel Bottomly, Stephen E Kurtz, PhD, Christopher A. Eide, Alisa Damnernsawad, Kyle Romine, Shyam Patel, Brian J. Druker, MD, Schannon K Mcweeney, Ravi Majeti, MD PhD, Jeffrey W. Tyner, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 175.
https://doi.org/10.1182/blood-2018-175
Published: 2018
Journal Articles

Distinct Mechanisms of Receptor Activation Are Associated with CSF3R Gain-of-Function Mutations

Haijiao Zhang, Julia E. Maxson, PhD, Kevin M Watanabe-Smith, PhD, Cody Coblentz, Jeffrey W. Tyner, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4985.
https://doi.org/10.1182/blood.V130.Suppl_1.4985.4985
Published: 2017
Journal Articles

Coexisting Oncogenic Signaling Pathway Mutations in Cnl/Acml/CMML/MPN-U

Haijiao Zhang, Daniel Bottomly, Libbey K. White, Beth Wilmot, PhD, Shannon Mcweeney, PhD, Jeffrey W. Tyner, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4213.
https://doi.org/10.1182/blood.V130.Suppl_1.4213.4213
Published: 2017
Journal Articles

Definition of the Minimal Truncated Elements Necessary for CSF3R Leukemogenic Potential

Haijiao Zhang, MD, Anna Reister Schultz, B.S., Samuel B Luty, BS, Sophie Means, B.S., Larry David, PhD, John Klimek, B.S., Daniel Bottomly, Beth Wilmot, Shannon McWeeney, PhD, Yulong Su, B.S., Jeffrey W. Tyner
Journal: Blood
Blood (2016) 128 (22): 2735.
https://doi.org/10.1182/blood.V128.22.2735.2735
Published: 2016
Journal Articles

Exome Sequencing Informs Mechanisms of Clinical Resistance to the FLT3-D835 Inhibitor Crenolanib

Haijiao Zhang, MD, Kevin Matthew Watanabe-Smith, BS, Daniel Bottomly, MS, Beth Wilmot, PhD, Shannon K. McWeeney, PhD, Hagop M. Kantarjian, MD, Judy Ho, Jeremy Davis, Blake Pond, MS, Gautam Borthakur, MD, Abhijit Ramachandran, MS, Jorge E. Cortes, Robert Collins, MD, Jeffrey W. Tyner, PhD
Journal: Blood
Blood (2015) 126 (23): 2468.
https://doi.org/10.1182/blood.V126.23.2468.2468
Published: 2015