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Journal Articles

The Flavonoid Brusatol Induces Apoptosis in Aggressive Lymphoma Cells and Exhibits Synergistic Effect with Venetoclax

Marta M. Szmyra, Sandra Haingartner, Sonja Jantscher, Katrin Pansy, Barbara Uhl, Hildegard T. Greinix, Peter Neumeister, Eva Bernhart, Christine Beham-Schmid, Michael A. Dengler, Burkhard Klösch, Alexander J.A. Deutsch

Blood (2022) 140 (Supplement 1): 4945–4946.

https://doi.org/10.1182/blood-2022-166678

Published: 2022

Journal Articles

Loss of Nr4a1 Causes an Elevated Expression of Co-Inhibitory Receptor:Ligand Axes and Results in a Diminished T Cell-Mediated Lymphoma Cell Killing in Aggressive Lymphoma

Katrin Pansy, Karoline Fechter, Kerstin Wenzl, Aditya Arra, Joseph P. Novak, Marta Szmyra, Sandra Haingartner, Alan G. Ramsay, Anne J. Novak, Hildegard T. Greinix, Christine Beham-Schmid, Peter Neumeister, Alexander J.A. Deutsch

Blood (2022) 140 (Supplement 1): 2038–2039.

https://doi.org/10.1182/blood-2022-163034

Published: 2022

Journal Articles

Introduction and Genetic Correction of Calreticulin Mutations in Human Hematopoietic Stem and Progenitor Cells Sheds Light on MPN Pathogenesis

Johannes Foßelteder, Angelika Schlacher, Gabriel Pabst, Bettina Amtmann, Wolfgang Schöll, Karl Kashofer, Christine Beham-Schmid, Peter Schlenke, Hildegard T. Greinix, Heinz Sill, Albert Woelfler, Armin Zebisch, Andreas Reinisch

Blood (2021) 138 (Supplement 1): 2541.

https://doi.org/10.1182/blood-2021-147919

Published: 2021

Journal Articles

Modeling the Development of SRSF2 Mutated Myeloid Malignancies By CRISPR/Cas9 Mediated Genome Engineering of Primary Human Hematopoietic Stem and Progenitor Cells

Gabriel Pabst, Johannes Foßelteder, Angelika Schlacher, Lisa Auinger, Daniel Martinez-Krams, Asiri Ediriwickrema, Karl Kashofer, Christine Beham-Schmid, Hildegard T. Greinix, Albert Woelfler, Peter Schlenke, Heinz Sill, Armin Zebisch, Ravi Majeti, Andreas Reinisch

Blood (2021) 138 (Supplement 1): 2160.

https://doi.org/10.1182/blood-2021-149591

Published: 2021

Journal Articles

Deregulated CXCR4-CXCL12 Signaling Impacts on the Pathogenesis of DLBCL

Katrin Pansy, MSc, BSc, Julia Feichtinger, Barbara Ehall, Barbara Uhl, Hildegard T. Greinix, MD, Katharina Prochazka, MD, Christine Beham-Schmid, Peter Neumeister, MD, Tanja Wrodnigg, Karoline Fechter, Alexander Deutsch

Blood (2019) 134 (Supplement_1): 1519.

https://doi.org/10.1182/blood-2019-130029

Published: 2019

Journal Articles

Essential Thrombocythemia Versus Pre-Fibrotic/Early Primary Myelofibrosis: Discrimination By Laboratory and Clinical Data

Martin Schalling, Andreas Gleiss, Bettina Gisslinger, Albert Wölfler, Veronika Buxhofer-Ausch, Georg Jeryczynski, MD, Maria-Theresa Krauth, MD, Ingrid Simonitsch-Klupp, MD, Christine Beham-Schmid, Jurgen Thiele, Heinz Gisslinger

Blood (2017) 130 (Supplement 1): 4201.

https://doi.org/10.1182/blood.V130.Suppl_1.4201.4201

Published: 2017

Journal Articles

NR4A3 Suppresses Lymphomagenesis I n Vitro and In Vivo by Induction of Similar Patterns of Pro-Apoptotic Genes like NR4A1

Alexander JA Deutsch, PhD, Beate Rinner, Martin Pichler, Karoline Fechter, Hildegard T. Greinix, MD, Chenguang Wang, Christine Beham-Schmid, MD, Peter Neumeister, MD

Blood (2016) 128 (22): 2728.

https://doi.org/10.1182/blood.V128.22.2728.2728

Published: 2016

Journal Articles

Survival in Essential Thrombocythemia and Prefibrotic Primary Myelofibrosis - Correlation of Clinical Phenotype with Histomorphological Diagnosis

Georg Jeryczynski, MD, Albert Woelfler, MD, Bettina Gisslinger, Martin Schalling, Sonja Burgstaller, MD, Veronika Buxhofer-Ausch, Maria Theresa Krauth, MD, Klaus Geissler, MD, Ernst Schlögl, MD, Thamer Sliwa, MD, Ana-Iris Schiefer, MD, Leonhard Muellauer, MD, Ingrid Simonitsch-Klupp, MD, Christine Beham-Schmid, MD, Jürgen Thiele, MDPhD, Heinz Gisslinger

Blood (2016) 128 (22): 1932.

https://doi.org/10.1182/blood.V128.22.1932.1932

Published: 2016

Journal Articles

An Autosomal-Recessive GFI1B Mutation Defines the Splice Isoform p37 As Essential for Biogenesis of Functional Human Platelets, but Dispensable for Erythropoiesis

Harald Schulze, PhD, Axel Schlagenhauf, PhD, Georgi Manukjan, PhD, Christine Beham-Schmid, MD, Oliver Andres, MD, Eva Klopocki, PhD, Eva-Maria König, Harald Haidl, MD, Simon Panzer, MD, Karina Althaus, MD, Wolfgang Muntean, MD, Wolfgang Schwinger, MD, Christian E. Urban, MD, Andreas Greinacher, MD, Tamam Bakchoul, MD, Markus Seidel, MD

Blood (2016) 128 (22): 2644.

https://doi.org/10.1182/blood.V128.22.2644.2644

Published: 2016

Journal Articles

Loss of NR4A1 Accelerates the Development of Aggressive Lymphomas in Myc Induced Cancerogenesis

Kerstin Wenzl, MSc, Katharina Troppan, MD, Beata Pursche, Marco Bischof, Christine Beham-Schmid, MD, Hildegard T. Greinix, MD, Peter Neumeister, MD, Alexander JA Deutsch, PhD

Blood (2015) 126 (23): 2444.

https://doi.org/10.1182/blood.V126.23.2444.2444

Published: 2015

Journal Articles

The Chemokine Receptor Profile As Distinctive Criterion Between Normal B-Cell Subsets and As Potential Discriminative Marker to Identify the Cell of Origin in Patients with Chronic Lymphocytic Leukemia and Richter Syndrome

Katharina Troppan, MD, Kerstin Wenzl, MSc, Peter Neumeister, MD, Christine Beham-Schmid, MD, Martina Przekopowitz, Hildegard T. Greinix, MD, Helmut Schaider, MD, Alexander JA Deutsch, PhD

Blood (2015) 126 (23): 3890.

https://doi.org/10.1182/blood.V126.23.3890.3890

Published: 2015

Journal Articles

NR4A3 Possesses Tumor Suppressive Properties like NR4A1 By Regulating Pro-Apoptotic Genes in Aggressive Lymphomas and Serves As a Potential Drug Target for Lymphoma Therapy

Alexander JA Deutsch, PhD, Beate Rinner, PhD, Kerstin Wenzl, MSc, Katharina Troppan, MD, Beata Pursche, Hildegard T. Greinix, MD, Christine Beham-Schmid, MD, Peter Neumeister, MD

Blood (2015) 126 (23): 2674.

https://doi.org/10.1182/blood.V126.23.2674.2674

Published: 2015

Journal Articles

Epigenetic and in vivo comparison of diverse MSC sources reveals an endochondral signature for human hematopoietic niche formation

Blood (2015) 125 (2): 249–260.

https://doi.org/10.1182/blood-2014-04-572255

Published: 2015

Includes: Multimedia, Supplemental data

Journal Articles

NR4A1-mediated apoptosis suppresses lymphomagenesis and is associated with a favorable cancer-specific survival in patients with aggressive B-cell lymphomas

Alexander J. A. Deutsch, Beate Rinner, Kerstin Wenzl, Martin Pichler, Katharina Troppan, Elisabeth Steinbauer, Daniela Schwarzenbacher, Sonja Reitter, Julia Feichtinger, Sascha Tierling, Andreas Prokesch, Marcel Scheideler, Anne Krogsdam, Gerhard G. Thallinger, Helmut Schaider, Christine Beham-Schmid, Peter Neumeister

Blood (2014) 123 (15): 2367–2377.

https://doi.org/10.1182/blood-2013-08-518878

Published: 2014

Includes: Supplemental data

Journal Articles

Imatinib Inhibits SCF-Induced Development Of Human Mast Cells In Vitro and Induces Profound and Selective Mast Cell Deficiency In Patients With Ph+ CML

Sabine Cerny-Reiterer, D.V.M, Anja Rabenhorst, Msc, Ph.D., Gabriele Stefanzl, Msc, Susanne Herndlhofer, Katharina Blatt, MSc, Ph.D., Gregor Hoermann, M.D., Ph.D., Leonhard Muellauer, M.D., Sigrid Baumgartner, M.D., Christine Beham-Schmid, M.D., Wolfgang R Sperr, M.D., Werner Linkesch, M.D., Christine Mannhalter, M.D., Michel Arock, PharmD, Ph.D, Karin Hartmann, M.D., Peter Valent

Blood (2013) 122 (21): 3988.

https://doi.org/10.1182/blood.V122.21.3988.3988

Published: 2013

Journal Articles

Distinct Chemokine Receptor Profile In Chronic Lymphocytic Leukaemia and Richter Transformed Diffuse Large B Cell Lymphomas Compared To Germinal Center B Cells and De Novo Diffuse Large B Cell Lymphomas

Kerstin Wenzl, MSc, Katharina Troppan, MD, Alexander JA Deutsch, Werner Linkesch, MD, Peter Neumeister, MD, Christine Beham-Schmid, MD

Blood (2013) 122 (21): 4852.

https://doi.org/10.1182/blood.V122.21.4852.4852

Published: 2013

Journal Articles

Organotypic Epigenetic Signature Predicts Bone and Marrow Niche Forming Capacity of Stromal Progenitors in a Novel Mouse Model in Vivo .

Andreas Reinisch, MD, PhD, Nathalie Etchart, PhD, Nicole A Hofmann, MSc, Margareta Frühwirth, Anna Ortner, MSc, Daniela Thaler, Birgit Feilhauer, Udo F Hartwig, Christine Beham-Schmid, MD, Slave Trajanosky, Wolfgang Wagner, MD, PhD, Frauke Alves, Katharina Schallmoser, MD, Michael Andreeff, MD, PhD, Dirk Strunk, MD

Blood (2012) 120 (21): 2987.

https://doi.org/10.1182/blood.V120.21.2987.2987

Published: 2012

Journal Articles

A Novel Role for Mesenchymal Stem/Progenitor Cells As Hypoxia Sensors During Initiation of Neo-Vasculogenesis in Vivo

Nicole A Hofmann, MSc, Anna Ortner, MSc, Rodrigo Jacamo, Ph.D, Andreas Reinisch, MD, PhD, Katharina Schallmoser, MD, Rokhsareh Rohban, Margareta Frühwirth, Nathalie Liechtenstein, Christine Beham-Schmid, MD, Werner Linkesch, Michael Andreeff, MD, PhD, Dirk Strunk, MD

Blood (2012) 120 (21): 613.

https://doi.org/10.1182/blood.V120.21.613.613

Published: 2012

Journal Articles

NR4A1 Mediated Apoptosis of Aggressive Lymphoma Cells Suppresses Tumor Growth in a Xenograft Model.

Alexander JA Deutsch, Beate Rinner, Martin Pichler, Sonja Reitter, Christine Beham-Schmid, MD, Peter Neumeister

Blood (2012) 120 (21): 2408.

https://doi.org/10.1182/blood.V120.21.2408.2408

Published: 2012

Journal Articles

Dissociation of In Vivo and in Vitro Differentiation Capacity of Human Mesenchymal Stem Cells Is Reflected by a Tissue Specific Epigenetic Memory

Andreas Reinisch, MD, PhD, Nathalie Liechtenstein, Nicole A Hofmann, MSc, Anna Ortner, Margareta Frühwirth, Katharina Schallmoser, MD, Christine Beham-Schmid, MD, Dirk Strunk, MD

Blood (2011) 118 (21): 2386.

https://doi.org/10.1182/blood.V118.21.2386.2386

Published: 2011

NARROW

The Flavonoid Brusatol Induces Apoptosis in Aggressive Lymphoma Cells and Exhibits Synergistic Effect with Venetoclax

Loss of Nr4a1 Causes an Elevated Expression of Co-Inhibitory Receptor:Ligand Axes and Results in a Diminished T Cell-Mediated Lymphoma Cell Killing in Aggressive Lymphoma

Introduction and Genetic Correction of Calreticulin Mutations in Human Hematopoietic Stem and Progenitor Cells Sheds Light on MPN Pathogenesis

Modeling the Development of SRSF2 Mutated Myeloid Malignancies By CRISPR/Cas9 Mediated Genome Engineering of Primary Human Hematopoietic Stem and Progenitor Cells

Deregulated CXCR4-CXCL12 Signaling Impacts on the Pathogenesis of DLBCL

Essential Thrombocythemia Versus Pre-Fibrotic/Early Primary Myelofibrosis: Discrimination By Laboratory and Clinical Data

NR4A3 Suppresses Lymphomagenesis I n Vitro and In Vivo by Induction of Similar Patterns of Pro-Apoptotic Genes like NR4A1

Survival in Essential Thrombocythemia and Prefibrotic Primary Myelofibrosis - Correlation of Clinical Phenotype with Histomorphological Diagnosis

An Autosomal-Recessive GFI1B Mutation Defines the Splice Isoform p37 As Essential for Biogenesis of Functional Human Platelets, but Dispensable for Erythropoiesis

Loss of NR4A1 Accelerates the Development of Aggressive Lymphomas in Myc Induced Cancerogenesis

The Chemokine Receptor Profile As Distinctive Criterion Between Normal B-Cell Subsets and As Potential Discriminative Marker to Identify the Cell of Origin in Patients with Chronic Lymphocytic Leukemia and Richter Syndrome

NR4A3 Possesses Tumor Suppressive Properties like NR4A1 By Regulating Pro-Apoptotic Genes in Aggressive Lymphomas and Serves As a Potential Drug Target for Lymphoma Therapy

Epigenetic and in vivo comparison of diverse MSC sources reveals an endochondral signature for human hematopoietic niche formation

NR4A1-mediated apoptosis suppresses lymphomagenesis and is associated with a favorable cancer-specific survival in patients with aggressive B-cell lymphomas

Imatinib Inhibits SCF-Induced Development Of Human Mast Cells In Vitro and Induces Profound and Selective Mast Cell Deficiency In Patients With Ph+ CML

Distinct Chemokine Receptor Profile In Chronic Lymphocytic Leukaemia and Richter Transformed Diffuse Large B Cell Lymphomas Compared To Germinal Center B Cells and De Novo Diffuse Large B Cell Lymphomas

Organotypic Epigenetic Signature Predicts Bone and Marrow Niche Forming Capacity of Stromal Progenitors in a Novel Mouse Model in Vivo .

A Novel Role for Mesenchymal Stem/Progenitor Cells As Hypoxia Sensors During Initiation of Neo-Vasculogenesis in Vivo

NR4A1 Mediated Apoptosis of Aggressive Lymphoma Cells Suppresses Tumor Growth in a Xenograft Model.

Dissociation of In Vivo and in Vitro Differentiation Capacity of Human Mesenchymal Stem Cells Is Reflected by a Tissue Specific Epigenetic Memory

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American Society of Hematology

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