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Sebastian Stasik
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Journal Articles

Age-Stratified Game-Theory-Informed Machine Learning of Molecular Alterations Unveils Prognostic Divergence in 3062 Pediatric and Adult Acute Myeloid Leukemia Patients

Jan-Niklas Eckardt, Waldemar Hahn, Rhonda E. Ries, Szymon Dariusz Chrost, Susann Winter, Sebastian Stasik, Christoph Röllig, Uwe Platzbecker, Carsten Müller-Tidow, Hubert Serve, Claudia D Baldus, Christoph Schliemann, Kerstin Schäfer-Eckart, Maher Hanoun, Martin Kaufmann, Andreas Burchert, Johannes Schetelig, Martin Bornhäuser, Markus Wolfien, Soheil Meshinchi, Christian Thiede, Jan Moritz Middeke
Journal: Blood
Blood (2024) 144 (Supplement 1): 2211.
https://doi.org/10.1182/blood-2024-198861
Published: 2024
Journal Articles

The Differential Impact of Secondary-Type Mutations in a Multinational Cohort of 5311 Intensively Treated Acute Myeloid Leukemia Patients

Jan-Niklas Eckardt, Marius Bill, Konstanze Döhner, Christian Rausch, Klaus H Metzeler, Karsten Spiekermann, Sebastian Stasik, Tim Sauer, Sebastian Scholl, Andreas Hochhaus, Martina Crysandt, Tim H. H. Brummendorf, Utz Krug, Bernhard Wörmann, Hermann Einsele, Wolfgang Hiddemann, Dennis Görlich, Maria Cristina Sauerland, Björn Steffen, Andreas Neubauer, Andreas Burchert, Kerstin Schaefer-Eckart, Wolfgang E. Berdel, Christoph Schliemann, Stefan W. Krause, Mathias Hänel, Maher Hanoun, Martin Kaufmann, Lars Fransecky, Jan Braess, Johannes Schetelig, Jan Moritz Middeke, Lars Bullinger, Michael Heuser, Felicitas R Thol, Hubert Serve, Claudia D Baldus, Uwe Platzbecker, Carsten Mueller-Tidow, Barbora Weinbergerova, Jiri Mayer, Pierre-Yves Dumas, Sarah Bertoli, Eric Delabesse, Christian Récher, Arnaud Pigneux, Tobias Herold, Arnold Ganser, Hartmut Döhner, Martin Bornhäuser, Christian Thiede, Christoph Röllig
Journal: Blood
Blood (2024) 144 (Supplement 1): 2934.
https://doi.org/10.1182/blood-2024-201945
Published: 2024
Journal Articles

Secondary-Type Mutations Do Not Impact the Favorable Outcome of NPM1 -Mutated Acute Myeloid Leukemia Patients - Results from a Large Cohort of Intensively Treated Patients

Marius Bill, Jan-Niklas Eckardt, Christian Rausch, Klaus H Metzeler, Karsten Spiekermann, Sebastian Stasik, Tim Sauer, Sebastian Scholl, Andreas Hochhaus, Martina Crysandt, Tim H. Brümmendorf, Utz Krug, Bernhard Wörmann, Wolfgang Hiddemann, Dennis Görlich, Maria Cristina Sauerland, Björn Steffen, Hermann Einsele, Andreas Neubauer, Andreas Burchert, Kerstin Schaefer-Eckart, Wolfgang E. Berdel, Christoph Schliemann, Stefan W. Krause, Mathias Hanel, Maher Hanoun, Martin Kaufmann, Lars Fransecky, Jan Braess, Leo Ruhnke, Johannes Schetelig, Jan Moritz Middeke, Hubert Serve, Claudia D Baldus, Uwe Platzbecker, Carsten Müller-Tidow, Martin Bornhäuser, Tobias Herold, Christian Thiede, Christoph Röllig
Journal: Blood
Blood (2023) 142 (Supplement 1): 721.
https://doi.org/10.1182/blood-2023-186160
Published: 2023
Journal Articles

Risk Stratification of Patients with RUNX1- mutated Acute Myeloid Leukemia

Christian Rausch, Roman Hornung, Aarif M. N. Batcha, Maja Rothenberg-Thurley, Stefanos A. Bamopoulos, Vindi Jurinovic, Bianka Ksienzyk, Stephanie Schneider, Annika Maria Dufour, Michaela Neusser, Maria Cristina Sauerland, Dennis Görlich, Utz Krug, Wolfgang E. Berdel, Bernhard J. Woermann, Jan Braess, Wolfgang Hiddemann, Manja Meggendorfer, Wolfgang Kern, Torsten Haferlach, Johannes Schetelig, Moritz Middeke, Sebastian Stasik, Katharina Egger-Heidrich, Christoph Röllig, Martin Bornhäuser, Christian Thiede, Claudia D Baldus, Carsten Müller-Tidow, Uwe Platzbecker, Hubert Serve, Wendy Stock, Geoffrey L Uy, John C. Byrd, Deedra Nicolet, Ann-Kathrin Eisfeld, Ulrich Mansmann, Karsten Spiekermann, Klaus H Metzeler, Tobias Herold
Journal: Blood
Blood (2023) 142 (Supplement 1): 2934.
https://doi.org/10.1182/blood-2023-174059
Published: 2023
Journal Articles

Mimicking Clinical Trials with Synthetic Acute Myeloid Leukemia Patients Using Generative Artificial Intelligence

Jan-Niklas Eckardt, Waldemar Hahn, Christoph Röllig, Sebastian Stasik, Uwe Platzbecker, Carsten Müller-Tidow, Hubert Serve, Claudia D Baldus, Christoph Schliemann, Kerstin Schäfer-Eckart, Maher Hanoun, Martin Kaufmann, Andreas Burchert, Christian Thiede, Johannes Schetelig, Martin Bornhäuser, Markus Wolfien, Jan Moritz Middeke
Journal: Blood
Blood (2023) 142 (Supplement 1): 2268.
https://doi.org/10.1182/blood-2023-179817
Published: 2023
Journal Articles

Overlapping features of therapy-related and de novo NPM1 -mutated AML

Clinical Trials & Observations
Jad Othman, Manja Meggendorfer, Enrico Tiacci, Christian Thiede, Richard Schlenk, Richard Dillon, Sebastian Stasik, Alessandra Venanzi, Sarah Bertoli, Eric Delabesse, Pierre-Yves Dumas, Arnaud Pigneux, Audrey Bidet, Amanda F. Gilkes, Ian Thomas, Maria Teresa Voso, Alessandro Rambaldi, Lorenzo Brunetti, Vincenzo M. Perriello, Vibeke Andresen, Bjorn T. Gjertsen, Maria Paola Martelli, Christian Récher, Christoph Röllig, Martin Bornhäuser, Hubert Serve, Carsten Müller-Tidow, Claudia D. Baldus, Tortsten Haferlach, Nigel Russell, Brunangelo Falini
Journal: Blood
Blood (2023) 141 (15): 1846–1857.
https://doi.org/10.1182/blood.2022018108
Published: 2023
Includes: Supplemental data
Journal Articles

Tandem Duplications of the UBTF gene in Adult AML: A Rare but Recurrent Alteration Associated with Myelodysplasia and Poor Outcome

Julia-Annabell Georgi, Sebastian Stasik, Sven Zukunft, Marita Hartwig, Christoph Röllig, Uta Oelschlaegel, Utz Krug, Tim Sauer, Sebastian Scholl, Andreas Hochhaus, Tim H Brümmendorf, Ralph Naumann, Björn Steffen, Hermann Einsele, Markus Schaich, Andreas Burchert, Andreas Neubauer, Kerstin Schaefer-Eckart, Christoph Schliemann, Stefan W. Krause, Mathias Haenel, Richard Noppeney, Ulrich Kaiser, Claudia D. Baldus, Martin Kaufmann, Carsten Müller-Tidow, Uwe Platzbecker, Wolfgang E. Berdel, Hubert Serve, Gerhard Ehninger, Martin Bornhaeuser, Johannes Schetelig, Frank P. Kroschinsky, Christian Thiede
Journal: Blood
Blood (2022) 140 (Supplement 1): 6262–6264.
https://doi.org/10.1182/blood-2022-164702
Published: 2022
Journal Articles

UBTF tandem Duplications Account for a Third of Advanced Pediatric MDS without Genetic Predisposition to Myeloid Neoplasia

Miriam Erlacher, Sebastian Stasik, Ayami Yoshimi, Julia-Annabell Georgi, Gudrun Göhring, Martina Rudelius, Irith Baumann, Stephan Schwarz-Furlan, Barbara De Moerloose, Henrik Hasle, Riccardo Masetti, Shlomit Barzilai-Birenboim, Jan Stary, Marcin W. Wlodarski, Natalia Rotari, Senthilkumar Ramamoorthy, Dirk Lebrecht, Peter Noellke, Brigitte Strahm, Charlotte M. Niemeyer, Christian Thiede
Journal: Blood
Blood (2022) 140 (Supplement 1): 1355–1356.
https://doi.org/10.1182/blood-2022-159002
Published: 2022
Journal Articles

CEBPA mutations in 4708 patients with acute myeloid leukemia: differential impact of bZIP and TAD mutations on outcome

Clinical Trials & Observations
Franziska Taube, Julia Annabell Georgi, Michael Kramer, Sebastian Stasik, Jan Moritz Middeke, Christoph Röllig, Utz Krug, Alwin Krämer, Sebastian Scholl, Andreas Hochhaus, Tim H. Brümmendorf, Ralph Naumann, Andreas Petzold, Roger Mulet-Lazaro, Peter J. M. Valk, Björn Steffen, Hermann Einsele, Markus Schaich, Andreas Burchert, Andreas Neubauer, Kerstin Schäfer-Eckart, Christoph Schliemann, Stefan W. Krause, Mathias Hänel, Richard Noppeney, Ulrich Kaiser, Claudia D. Baldus, Martin Kaufmann, Sylvia Herold, Friedrich Stölzel, Katja Sockel, Malte von Bonin, Carsten Müller-Tidow, Uwe Platzbecker, Wolfgang E. Berdel, Hubert Serve, Gerhard Ehninger, Martin Bornhäuser, Johannes Schetelig, Christian Thiede, for the Study Alliance Leukemia (SAL)
Journal: Blood
Blood (2022) 139 (1): 87–103.
https://doi.org/10.1182/blood.2020009680
Published: 2022
Includes: Supplemental data
Journal Articles

Prediction of Complete Remission and Survival in Acute Myeloid Leukemia Using Supervised Machine Learning

Jan-Niklas Eckardt, Christoph Rollig, Michael Kramer, Sebastian Stasik, Julia-Annabell Georgi, Peter Heisig, Frank P. Kroschinsky, Johannes Schetelig, Uwe Platzbecker, Carsten Müller-Tidow, Tim Sauer, Hubert Serve, Claudia D. Baldus, Kerstin Schaefer-Eckart, Martin Kaufmann, Stefan W. Krause, Mathias Haenel, Christoph Schliemann, Maher Hanoun, Christian Thiede, Martin Bornhaeuser, Karsten Wendt, Jan Moritz Middeke
Journal: Blood
Blood (2021) 138 (Supplement 1): 108.
https://doi.org/10.1182/blood-2021-149582
Published: 2021
Journal Articles

Impact of Genetic Abnormalities and Measurable Residual Disease Levels on Outcome in Patients with MDS/AML Pre-Emptively Treated with Azacitidine: Correlative Results of the Prospective RELAZA2 Trial

Sabine Kayser, MD, Jan Moritz Middeke, MD, Michael Kramer, Katja Sockel, MD, Sebastian Stasik, PhD, Regina Herbst, MD, Lars R. Fransecky, MD, Dominik Wolf, Univ. Prof. Dr., Schumacher Martin, MD, Alwin Krämer, MD, Richard Noppeney, MD, Juergen Novotny, MD, Gesine Bug, Katharina S. Götze, Karsten Spiekermann, MD, Matthias Stelljes, MD, Jan-Henrik Mikesch, PD, MD, Marion Subklewe, MD, Antje Schubert, Anke Mütherig, MD, Tilmann Bochtler, MD, Marika Mende, MD, Friedrich Stoelzel, PD, MD, Anne Kubasch, MD, Malte Von Bonin, MD, Mathias Haenel, MD, Ulrich Duehrsen, MD, Johannes Schetelig, MDMSc, Christoph Rollig, MD MSC, Claudia D Baldus, MD, Gerhard Ehninger, MD, Carsten Müller-Tidow, MD, Hubert Serve, MD PhD, Martin Bornhäuser, MD, Uwe Platzbecker, Christian Thiede, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 10–11.
https://doi.org/10.1182/blood-2020-138427
Published: 2020
Journal Articles

Clinical Characteristics and Outcome in IDH1/2 Mutant AML Patients - Analysis of 3898 Newly Diagnosed Patients with Acute Myeloid Leukemia

Jan Moritz Middeke, MD, Christoph Rollig, MD MSC, Michael Kramer, M.Sc., Alwin Kramer, MD, Tilman Bochtler, MD, Sebastian Scholl, MD, Andreas Hochhaus, MD, Edgar Jost, MD, Tim H. Brümmendorf, MD, Ralph Naumann, MD, Björn Steffen, MD, Volker Kunzmann, MD PhD, Hermann Einsele, MD, Markus Schaich, MD, Andreas Burchert, MD, Andreas Neubauer, Kerstin Schäfer-Eckart, MD, Christoph Schliemann, MD, Stefan W Krause, MD, Regina Herbst, MD, Mathias Hänel, MD, Norbert Frickhofen, MD, Richard Noppeney, MD, Ulrich Kaiser, MD, Claudia D. Baldus, MD, Martin Kaufmann, MD, Zdenek Racil, MD, Sebastian Stasik, PhD, Katja Sockel, MD, Malte von Bonin, MD, Carsten Müller-Tidow, Uwe Platzbecker, Wolfgang E. Berdel, MD, Jiri Mayer, MD, Hubert Serve, MD, Gerhard Ehninger, MD, Johannes Schetelig, MD MSc, Christian Thiede, MD, Friedrich Stoelzel
Journal: Blood
Blood (2018) 132 (Supplement 1): 1461.
https://doi.org/10.1182/blood-2018-99-118128
Published: 2018
Journal Articles

EZH2 Mutations and Impact on Clinical Outcome Analyzed in 1604 Patients with Acute Myeloid Leukemia

Sebastian Stasik, PhD, Jan Moritz Middeke, MD, Michael Kramer, M.Sc., Christoph Rollig, MD MSC, Alwin Krämer, MD, Sebastian Scholl, MD, Andreas Hochhaus, MD, Martina Crysandt, Tim H. Brümmendorf, MD, Ralph Naumann, MD, Björn Steffen, MD, Volker Kunzmann, MD PhD, Hermann Einsele, MD, Markus Schaich, MD, Andreas Burchert, MD, Andreas Neubauer, Kerstin Schäfer-Eckart, MD, Christoph Schliemann, MD, Stefan W Krause, MD, Regina Herbst, MD, Mathias Hänel, MD, Norbert Frickhofen, MD, Richard Noppeney, MD, Ulrich Kaiser, MD, Claudia D. Baldus, MD, Martin Kaufmann, MD, Zdenek Racil, MD, Uwe Platzbecker, Wolfgang E. Berdel, MD, Jiri Mayer, MD, Hubert Serve, MD, Carsten Müller-Tidow, Gerhard Ehninger, MD, Martin Bornhäuser, Johannes Schetelig, MD, Christian Thiede, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1528.
https://doi.org/10.1182/blood-2018-99-114421
Published: 2018
Journal Articles

Real World Data on Decitabine Treatment in 296 Patients with Acute Myeloid Leukemia: Outcome and Impact of TP53 Mutations

Christoph Rollig, MD MSC, Jan Moritz Middeke, MD, Sebastian Stasik, Armin Zebisch, MD, Heinz Sill, MD, Michael Kramer, M.Sc., Sebastian Scholl, MD, Andreas Hochhaus, MD, Edgar Jost, Tim H. Brümmendorf, MD, Ralph Naumann, MD, Björn Steffen, Hubert Serve, Heidi Altmann, Volker Kunzmann, MD PhD, Hermann Einsele, Stefani Barbara Parmentier, MD, Markus Schaich, MD, Andreas Burchert, MD, Andreas Neubauer, MD, Frank Heits, MD, Wolfgang E. Berdel, Katja Sockel, MD, Friedrich Stoelzel, MD, Uwe Platzbecker, MD, Gerhard Ehninger, Martin Bornhäuser, MD, Johannes Schetelig, MD, Christian Thiede, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3896.
https://doi.org/10.1182/blood.V130.Suppl_1.3896.3896
Published: 2017
Journal Articles

Differences Between CEBPA bZIP and TAD Mutations and Their Effect on Outcome-an Analysis in 4578 Patients with Acute Myeloid Leukemia

Julia-Annabell Georgi, Franziska Taube, MD, Michael Kramer, MSc, Sylvia Herold, PhD, Kerstin Schaefer-Eckart, MD, Norbert Schmitz, MD, PhD, Christian Eberlein, PhD, Sebastian Stasik, PhD, Walter E Aulitzky, MD, Alwin Kraemer, MD, Wolf Roesler, MD, Mathias Haenel, MD, Hermann Einsele, MD, Claudia D. Baldus, MD, Jan Moritz Middeke, MD, Uwe Platzbecker, MD, Christoph Roellig, MD, Hubert Serve, MD, Wolfgang E Berdel, MD, Gerhard Ehninger, MD, Martin Bornhaeuser, MD, Johannes Schetelig, MD PhD, Christian Thiede, MD
Journal: Blood
Blood (2016) 128 (22): 283.
https://doi.org/10.1182/blood.V128.22.283.283
Published: 2016