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Journal Articles

Unfavorable outcomes in pediatric PAX5r B-cell precursor acute lymphoblastic leukemia: FLT3 targeting as a potential novel treatment strategy

Free
Nicolò Peccatori, Alessia Curto, Daniela Silvestri, Stefano Rebellato, Željko Antić, Sanil Bhatia, Anke K. Bergmann, Arndt Borkhardt, Martin Zimmermann, Sabine Strehl, Karin Nebral, Manuel Quadri, Chiara Palmi, Michela Bardini, Daniela Guardo, Luca Lo Nigro, Rosanna Parasole, Maria Caterina Putti, Franco Locatelli, Julia Alten, Martin Stanulla, Maria Valsecchi, Barbara Buldini, Valentino Conter, Andrea Biondi, Adriana Balduzzi, Martin Schrappe, Andishe Attarbaschi, Gunnar Cario, Carmelo Rizzari, Giovanni Cazzaniga, Grazia Fazio
Journal: Blood
Blood (2025) 146 (Supplement 1): 760.
https://doi.org/10.1182/blood-2025-760
Published: 2025
Journal Articles

Unravelling the biological and clinical features of childhood B-cell precursor acute lymphoblastic leukemia with monosomy 7

Free
Agata Pastorczak, Kinga Ostrowska, Kamila Wypyszczak, Karolina Miarka-Walczyk, Zuzanna Urbanska, Monika Lejman, Natalia Ochocka, Anke Bergmann, Karin Nebral, Sabine Strehl, Andishe Attarbaschi, Giovanni Cazzaniga, Judith Boer, Roland Kuiper, Shlomit Barzilai-Birenboim, Zdenka Krenova, Henrik Hasle, Lisa Russell, Wojciech Michal Mlynarski
Journal: Blood
Blood (2025) 146 (Supplement 1): 5145.
https://doi.org/10.1182/blood-2025-5145
Published: 2025
Journal Articles

Clinical, cytogenetic and molecular characteriszation of Mecom- rearranged pediatric de novo Acute Myeloid Leukemia (AML): A retrospective cohort study of the international-berlin-frankfurt-Münster (I-BFM) AML-study group

Free
Anna Cvrtak, Karin Nebral, Heidrun Boztug, Oussama Abla, Evangelia Antoniou, Barbara Buldini, Malgorzata Czogala, Valerie de Haas, Amber Gibson, Mane Gizhlaryan, Bianca Goemans, Irén Haltrich, Hiroto Inaba, Nkemdirim Jacob, Kristian Juul-Dam, Charikleia Kelaidi, Jeffery Klco, Nora Mühlegger, Tasleema Patel, Martina Pigazzi, Nastassja Scheidegger, Marketa Zaliova, Jonas Abrahamsson, Todd Cooper, Branko Cuglievan, Barbara De Moerloose, Brenda Gibson, Henrik Hasle, Gertjan Kaspers, Franco Locatelli, Arnaud Petit, Sophia Polychronopoulou, Dirk Reinhardt, Patricia Rubio, Jan Stary, Sarah Tasian, Daisuke Tomizawa, Michael Dworzak
Journal: Blood
Blood (2025) 146 (Supplement 1): 1608.
https://doi.org/10.1182/blood-2025-1608
Published: 2025
Journal Articles

Nanopore Cas9-Targeted Long-Read Sequencing - a Fast and Flexible Diagnostic Tool for the Identification of B-Cell Acute Lymphoblastic Leukemia Associated Gene Rearrangements

Free
Kathrin Liszt, Maximilian von der Linde, Dagmar Schinnerl, Karin Nebral, Sabine Strehl, Andishe Attarbaschi, Oskar A. Haas, Stefan Koehrer
Journal: Blood
Blood (2023) 142 (Supplement 1): 2984.
https://doi.org/10.1182/blood-2023-178519
Published: 2023
Journal Articles

Deciphering the Somatic and Germline Structural Variation Landscape in Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia By Whole Genome Optical Mapping

Free
Danielle Brandes, Triantafyllia Brozou, Karin Nebral, Anke K. Bergmann, Oskar A. Haas, Stefan Köhrer, Martin Stanulla, Ute Fischer, Arndt Borkhardt, Rabea Wagener
Journal: Blood
Blood (2022) 140 (Supplement 1): 9203–9204.
https://doi.org/10.1182/blood-2022-163110
Published: 2022
Journal Articles

Association of unbalanced translocation der(1;7) with germline GATA2 mutations

Free
Emilia J. Kozyra, Gudrun Göhring, Dennis D. Hickstein, Katherine R. Calvo, Courtney D. DiNardo, Michael Dworzak, Valerie de Haas, Jan Starý, Henrik Hasle, Akiko Shimamura, Mark D. Fleming, Hiroto Inaba, Sara Lewis, Amy P. Hsu, Steven M. Holland, Danielle E. Arnold, Cristina Mecucci, Siobán B. Keel, Alison A. Bertuch, Kiran Tawana, Shlomit Barzilai, Shinsuke Hirabayashi, Masahiro Onozawa, Shaohua Lei, Helena Alaiz, Hajnalka Andrikovics, David Betts, Berna H. Beverloo, Jochen Buechner, Martin Čermák, José Cervera, Olga Haus, Kirsi Jahnukainen, Kalliopi N. Manola, Karin Nebral, Francesco Pasquali, Joelle Tchinda, Dominik Turkiewicz, Nadine Van Roy, Zuzana Zemanova, Victor B. Pastor, Brigitte Strahm, Peter Noellke, Charlotte M. Niemeyer, Brigitte Schlegelberger, Ayami Yoshimi, Marcin W. Wlodarski
Journal: Blood
Blood (2021) 138 (23): 2441–2445.
https://doi.org/10.1182/blood.2021012781
Published: 2021
Includes: Supplemental data
Journal Articles

Targeted Next Generation Sequencing Reveals a Third Breakpoint Cluster Region and New Partner Genes in the KMT2A Recombinome

Free
Claus Meyer, Patrizia Larghero, Bruno Lopes, Aurélie Caye-Eude, Hélène Cavé, Marius Külp, Matthew James Smith, Rosemary Sutton, Nicola Venn, Karin Nebral, Susanne Kubetzko, Beat Schaefer, Grazia Fazio, Giovanni Cazzaniga, Mariana Emerenciano, Rolf Marschalek
Journal: Blood
Blood (2021) 138 (Supplement 1): 3327.
https://doi.org/10.1182/blood-2021-146172
Published: 2021
Journal Articles

Novel Recurrent Germline JAK2 G571S Variant in Childhood Acute B-Lymphoblastic Leukemia: A Double Hit One Pathway Scenario

Free
Franziska Auer, PhD, Minhui Lin, PhD, Karin Nebral, PhD, Christoph G. W. Gertzen, PhD, Oskar A. Haas, MD, Michaela Kuhlen, MD, Holger Gohlke, PhD, Shai Izraeli, MD, Jan Trka, MD PhD, Jianda Hu, PhD, Arndt Borkhardt, MD, Julia Hauer, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 387.
https://doi.org/10.1182/blood-2018-99-115293
Published: 2018
Journal Articles

A Comprehensive FISH- and Array-Based Diagnostic Screeningstrategy for the Assessment of Clinically Relevant Genetic Parameters: A Prospective Analysis of 205 Childhood ALL Cases

Free
Oskar A. Haas, MD, Karin Nebral, PhD, Sabrina Haslinger, BSc, Andrea Inthal, PhD, Margit König, Sabine Strehl, PhD, Renate Panzer-Grümayer, MD, Andishe Attarbaschi, MD, Georg Mann, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4082.
https://doi.org/10.1182/blood-2018-99-115761
Published: 2018
Journal Articles

Prognostic Value of Rare IKZF1 deletions in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia: An International Collaborative Study

Free
Judith M. Boer, PhD, Arian van der Veer, MD PhD, Dimitris Rizopoulos, PhD, Marta Fiocco, PhD, Edwin Sonneveld, PhD, Hester A. de Groot-Kruseman, PhD, Roland P. Kuiper, PhD, Peter M. Hoogerbrugge, MD PhD, Martin A. Horstmann, MD PhD, Marketa Zaliova, MD PhD, Chiara Palmi, Jan Trka, MD, PhD, Prof., Eva Fronkova, MD, PhD, Mariana Emerenciano, PhD, Maria do Socorro Pombo-de-Oliveira, PhD, Wojciech Mlynarski, MDPhD, Tomasz Szczepanski, MD PhD, Karin Nebral, PhD, Andishe Attarbaschi, MD PhD, Nicola C. Venn, PhD, Rosemary Sutton, PhD, Claire Schwab, BSc, Amir Enshaei, PhD, Ajay J. Vora, Martin Stanulla, MD, Martin Schrappe, MD, Gianni Cazzaniga, PhD, Valentino Conter, MD PhD, Martin Zimmerman, PhD, Anthony V. Moorman, PhD, Rob Pieters, Monique L. Den Boer, MSc, PhD
Journal: Blood
Blood (2014) 124 (21): 368.
https://doi.org/10.1182/blood.V124.21.368.368
Published: 2014
Journal Articles

A Novel Fusion between ETV6 and NCOA2 Defines a New Entity of Acute Leukemia with Co-Expression of T-Cell and Myeloid Markers.

Free
Sabine Strehl, Karin Nebral, Margit König, Jochen Harbott, Bella Bielorai, Stephanie Struski, Shai Izraeli, Oskar A. Haas
Journal: Blood
Blood (2006) 108 (11): 804.
https://doi.org/10.1182/blood.V108.11.804.804
Published: 2006
Journal Articles

Topoisomerase (DNA) II Beta 180 kDa TOP2B ) - A New NUP98 Fusion Partner.

Free
Sabine Strehl, PhD, Karin Nebral, MSc, Helmut H. Schmidt, MD, Oskar A. Haas, MD
Journal: Blood
Blood (2005) 106 (11): 2849.
https://doi.org/10.1182/blood.V106.11.2849.2849
Published: 2005