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Mahesh Shrestha
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Journal Articles

A FOXO1-induced oncogenic network defines the AML1-ETO preleukemic program

Shan Lin, Anetta Ptasinska, Xiaoting Chen, Mahesh Shrestha, Salam A. Assi, Paulynn S. Chin, Maria R. Imperato, B. J. Aronow, Jingsong Zhang, Matthew T. Weirauch, Constanze Bonifer, James C. Mulloy
Journal: Blood
Blood (2017) 130 (10): 1213–1222.
https://doi.org/10.1182/blood-2016-11-750976
Published: 2017
Includes: Supplemental data
Journal Articles

The full transforming capacity of MLL-Af4 is interlinked with lymphoid lineage commitment

Brief Report
Shan Lin, Roger T. Luo, Mahesh Shrestha, Michael J. Thirman, James C. Mulloy
Journal: Blood
Blood (2017) 130 (7): 903–907.
https://doi.org/10.1182/blood-2017-04-777185
Published: 2017
Includes: Supplemental data
Journal Articles

Protease-Activated Receptor 1 (PAR-1) Inhibits Proliferation but Enhances Leukemia Stem Cell Activity in Acute Myeloid Leukemia

Susumu Goyama, MD PhD, Mahesh Shrestha, Janet Schibler, Leah Rosenfeldt, Whitney Miller, Eric O'Brien, Benjamin Mizukawa, MD, Toshio Kitamura, MD PhD, Joseph S. Palumbo, MD, James C. Mulloy, PhD
Journal: Blood
Blood (2016) 128 (22): 2730.
https://doi.org/10.1182/blood.V128.22.2730.2730
Published: 2016
Journal Articles

AML cells are differentially sensitive to chemotherapy treatment in a human xenograft model

e-blood
Mark Wunderlich, Benjamin Mizukawa, Fu-Sheng Chou, Christina Sexton, Mahesh Shrestha, Yogen Saunthararajah, James C. Mulloy
Journal: Blood
Blood (2013) 121 (12): e90–e97.
https://doi.org/10.1182/blood-2012-10-464677
Published: 2013
Journal Articles

Stroma-Free Ex Vivo Expanded, CD34+ Cord Blood-Derived NK Cells Retain Lytic Activity After Long-Term Engraftment in NSGS Mice

Mark Wunderlich, MS, Mahesh Shrestha, MS, Lin Kang, PhD, Eric Law, MS, Vladimir Jankovic, MD, Xiaokui Zhang, PhD, Uri Herzberg, PhD, DVM, Stewart Abbot, PhD, Robert Hariri, MD, PhD, James C. Mulloy, PhD
Journal: Blood
Blood (2012) 120 (21): 580.
https://doi.org/10.1182/blood.V120.21.580.580
Published: 2012
Journal Articles

The thrombopoietin/MPL/Bcl-xL pathway is essential for survival and self-renewal in human preleukemia induced by AML1-ETO

Fu-Sheng Chou, Andrea Griesinger, Mark Wunderlich, Shan Lin, Kevin A. Link, Mahesh Shrestha, Susumu Goyama, Benjamin Mizukawa, Shuhong Shen, Guido Marcucci, James C. Mulloy
Journal: Blood
Blood (2012) 120 (4): 709–719.
https://doi.org/10.1182/blood-2012-01-403212
Published: 2012
Includes: Supplemental data
Journal Articles

Rac GTPase Survival Signaling Through Anti-Apoptotic Bcl-2 Proteins Reveals a Target for Combination Therapy in MLL-AF9 Acute Myeloid Leukemia

Benjamin Mizukawa, MD, Mahesh Shrestha, MS, Mark Wunderlich, MS, Fu-Sheng Chou, MD, PhD, Andrea Griesinger, BS, Ashish Kumar, MBBS, PhD, Yi Zheng, PhD, David A. Williams, MD, James C. Mulloy, PhD
Journal: Blood
Blood (2011) 118 (21): 1536.
https://doi.org/10.1182/blood.V118.21.1536.1536
Published: 2011
Journal Articles

Inhibition of Rac GTPase signaling and downstream prosurvival Bcl-2 proteins as combination targeted therapy in MLL-AF9 leukemia

Benjamin Mizukawa, Junping Wei, Mahesh Shrestha, Mark Wunderlich, Fu-Sheng Chou, Andrea Griesinger, Chad E. Harris, Ashish R. Kumar, Yi Zheng, David A. Williams, James C. Mulloy
Journal: Blood
Blood (2011) 118 (19): 5235–5245.
https://doi.org/10.1182/blood-2011-04-351817
Published: 2011
Journal Articles

Adaptation of a Xenograft AML Model to Evaluate Chemotherapeutic Efficacy In Vivo

Mark Wunderlich, M.S., Fu-Sheng Chou, M.D., Mahesh Shrestha, Benjamin Mizukawa, M.D., James C. Mulloy, PhD
Journal: Blood
Blood (2010) 116 (21): 3304.
https://doi.org/10.1182/blood.V116.21.3304.3304
Published: 2010