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Journal Articles

Inhibition of Rac GTPase signaling and downstream prosurvival Bcl-2 proteins as combination targeted therapy in MLL-AF9 leukemia

Benjamin Mizukawa, Junping Wei, Mahesh Shrestha, Mark Wunderlich, Fu-Sheng Chou, Andrea Griesinger, Chad E. Harris, Ashish R. Kumar, Yi Zheng, David A. Williams, James C. Mulloy
Journal: Blood
Blood (2011) 118 (19): 5235–5245.
https://doi.org/10.1182/blood-2011-04-351817
Published: 2011
Journal Articles

Bcl-XL Is a Critical Mediator of Rac Signaling in MLL-AF9-Induced Acute Myeloid Leukemia.

Benjamin Mizukawa, MD, Junping Wei, MD, PhD, Mark Wunderlich, MS, Fu-Sheng Chou, MD, Yi Zheng, PhD, David A. Williams, MD, James C. Mulloy, PhD
Journal: Blood
Blood (2009) 114 (22): 1971.
https://doi.org/10.1182/blood.V114.22.1971.1971
Published: 2009
Journal Articles

Rac GTPases Are Required for MLL-AF9-Induced Mixed Lineage Leukemia.

Junping Wei, MD, PhD, Mark Wunderlich, MS, Chad Harris, MS, Benjamin Mizukawa, M.D., Yi Zheng, PhD, David A. Williams, MD, James C Mulloy, PhD
Journal: Blood
Blood (2008) 112 (11): 3368.
https://doi.org/10.1182/blood.V112.11.3368.3368
Published: 2008
Journal Articles

Environmental Factors Determine Lineage Fate in a Human Model of MLL-AF9 Leukemia.

Junping Wei, MD, PhD, Wunderlich Mark, M.S., Catherine Fox, B.S., Jorge F. DiMartino, M.D., Ph.D, James C. Mulloy, Ph.D
Journal: Blood
Blood (2007) 110 (11): 3374.
https://doi.org/10.1182/blood.V110.11.3374.3374
Published: 2007
Journal Articles

AML1-ETO Inhibits DNA Repair Pathways and Promotes the Accumulation of DNA Damage and the Activation of p53.

Ondrej Krejci, MD, PhD, Mark Wunderlich, Junping Wei, MD, PhD, Paul R. Andreassen, PhD, Thomas X. Lu, James C. Mulloy, PhD
Journal: Blood
Blood (2006) 108 (11): 1412.
https://doi.org/10.1182/blood.V108.11.1412.1412
Published: 2006
Journal Articles

Immortalization of Human HSPC by a Self-Renewal Signal Coupled with Telomere Maintenance.

Junping Wei, MD, PhD, Mark Wunderlich, Ondrej Krejci, MD PhD, Sara Alvarez, PhD, Juan Cigudosa, PhD, James C. Mulloy, PhD
Journal: Blood
Blood (2006) 108 (11): 2547.
https://doi.org/10.1182/blood.V108.11.2547.2547
Published: 2006
Journal Articles

Leukemic Transformation of Primary Human CD34+ Progenitor Cells by MLL-AF9 Recapitulates the Phenotype and Gene Expression Profile of MLL Rearranged AML.

James C. Mulloy, PhD, Junping Wei, MD PhD, Catherine Rettig, Mark Wunderlich, Sara Alvarez, PhD, Juan Cigudosa, PhD, Michael Jansen, MD, Jorge F. DiMartino, MD PhD
Journal: Blood
Blood (2006) 108 (11): 2210.
https://doi.org/10.1182/blood.V108.11.2210.2210
Published: 2006
Journal Articles

Human CD34 + cells expressing the inv(16) fusion protein exhibit a myelomonocytic phenotype with greatly enhanced proliferative ability

Mark Wunderlich, Ondrej Krejci, Junping Wei, James C. Mulloy
Journal: Blood
Blood (2006) 108 (5): 1690–1697.
https://doi.org/10.1182/blood-2005-12-012773
Published: 2006
Journal Articles

Telomerase Promotes the Self-Renewal of Human Hematopoietic Progenitor Cells but Does Not Maintain Telomere Length.

Junping Wei, MD, PhD, Mark Wunderlich, MS, James C. Mulloy, PhD
Journal: Blood
Blood (2005) 106 (11): 647.
https://doi.org/10.1182/blood.V106.11.647.647
Published: 2005
Journal Articles

Human CD34+ Cells Expressing CBFβ-MYH11 Exhibit a Myelomonocytic Phenotype with Greatly Enhanced Proliferative Ability.

Mark Wunderlich, MS, Ondrej Krejci, MD/PhD, Junping Wei, MD/PhD, Thomas X. Lu, James C. Mulloy, PhD
Journal: Blood
Blood (2005) 106 (11): 1379.
https://doi.org/10.1182/blood.V106.11.1379.1379
Published: 2005