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Journal Articles

The PTPN2/PTPN1 Inhibitor Abbv-CLS-484 Augments Immune Responses Against Leukemic Blasts and Impedes Leukemia Cell Proliferation in AML Alone and in Combination with Venetoclax

Niklas Kruppa, Moritz Kruppa, Jana Muschhammer, Nadine Felber, Franziska Brauneck, Franziska Modemann, Jasmin Wellbrock, Walter Fiedler

Blood (2024) 144 (Supplement 1): 1374.

https://doi.org/10.1182/blood-2024-201504

Published: 2024

Journal Articles

CD39 Is Predominantly Expressed in Adverse AML Patients and Blockade By a New Anti-CD39 Nanobody Increases Lysis of AML Blasts

Franziska Brauneck, Stefan Menzel, Niklas Kruppa, Fritz Koch-Nolte, Walter Fiedler, Jasmin Wellbrock

Blood (2024) 144 (Supplement 1): 1397.

https://doi.org/10.1182/blood-2024-206914

Published: 2024

Journal Articles

Loss of SMARCA4 Leads to an Impaired Hematopoiesis in Mice

Franziska Modemann, Leoni Ramke, Erkin Erdal, Melanie Schoof, Carolin Göbel, Sina Neyazi, Carsten Bokemeyer, Jasmin Wellbrock, Ulrich Schüller, Walter Fiedler

Blood (2023) 142 (Supplement 1): 1377.

https://doi.org/10.1182/blood-2023-178137

Published: 2023

Journal Articles

Blockade of Tigit on AML-Derived M2 Macrophages Results in Reprograming into the M1 Phenotype and Enhances CD47-Mediated Phagocytosis

Franziska Brauneck, Brit Fischer, Jasmin Wellbrock, Carsten Bokemeyer, Julian Schulze zur Wiesch, Friedrich Haag, Christin Ackermann, Walter Fiedler

Blood (2021) 138 (Supplement 1): 3351.

https://doi.org/10.1182/blood-2021-148075

Published: 2021

Journal Articles

Increased Frequency of TOX + CD39 + TIGIT + CD73 - CD8 + T Cells in Patients with Newly Diagnosed AML

Franziska Brauneck, MD, Christin Ackermann, PhD, Nils Wildner, Jasmin Wellbrock, PhD, Carsten Bokemeyer, MD, Julian Schulze zur Wiesch, MD, Walter Fiedler, MD

Blood (2020) 136 (Supplement 1): 36.

https://doi.org/10.1182/blood-2020-139917

Published: 2020

Journal Articles

Mebendazole Mediates Its Anti-Leukemic Effects By Proteasomal Degradation of GLI Transcription Factors Via Inhibition of HSP70/90-Chaperone Activity in Acute Myeloid Leukemia in a Preclinical and Clinical Setting

Fabian Freisleben, Hauke Stamm, PhD, Jana Muschhammer, Vanessa Thaden, Franziska Modemann, MD, Alexander Krispien, Franziska Brauneck, Jasmin Wellbrock, PhD, Walter Fiedler, MD

Blood (2019) 134 (Supplement_1): 5050.

https://doi.org/10.1182/blood-2019-129973

Published: 2019

Journal Articles

Mebendazole Exerts Potent Anti-Leukemic Effects By Downregulating Protein Levels of Hedgehog Transcription Factors GLI1 and GLI2

Fabian Freisleben, Hauke Stamm, PhD, Jana Muschhammer, Alexander Krispien, Vanessa Thaden, Jasmin Wellbrock, PhD, Walter Fiedler, MD

Blood (2018) 132 (Supplement 1): 5145.

https://doi.org/10.1182/blood-2018-99-118189

Published: 2018

Journal Articles

The Actin Binding Protein Plastin-3 Is Involved in the Pathogenesis of Acute Myeloid Leukemia

Arne Velthaus, Kerstin Cornils, PhD, Saskia Grüb, MSc, Hauke Stamm, MSc, Daniel Wicklein, PhD, Carsten Bokemeyer, MD, Michael Heuser, MD, Sabine Windhorst, PhD, Walter Fiedler, MD, Jasmin Wellbrock, PhD

Blood (2016) 128 (22): 1662.

https://doi.org/10.1182/blood.V128.22.1662.1662

Published: 2016

Journal Articles

Expression of Novel Immune Checkpoint Molecules PVR and PVRL2 Confers a Negative Prognosis to Patients with Acute Myeloid Leukemia and Their Blockade Augments T-Cell Mediated Lysis of AML Cells Alone or in Combination with the BiTE ® Antibody Construct AMG 330

Hauke Stamm, MSc, Felix Klingler, cand. MD, Daniela Pende, MD, Eik Vettorazzi, MSc, Michael Heuser, MD, Ulrike Mock, PhD, Carsten Bokemeyer, MD, Roman Kischel, MD, Sabine Stienen, PhD, Matthias Friedrich, PhD, Michael Lutteropp, PhD, Dirk Nagorsen, MD, Jasmin Wellbrock, PhD, Walter Fiedler, MD

Blood (2015) 126 (23): 789.

https://doi.org/10.1182/blood.V126.23.789.789

Published: 2015

Journal Articles

Expression Of Hedgehog Pathway Mediator Gli2 Represents a Clinically Negative Prognostic Marker In Acute Myeloid Leukemia and Its Inhibitor GANT61 Exerts Anti-Leukemic Effects In Vitro

Jasmin Wellbrock, Ph.D., Julian M Koehler, Katharina Wagner, MD, Emily Latuske, M.Sc., Hauke Stamm, M.Sc., Eik Vettorazzi, M.Sc., Gabi Vohwinkel, M.Sc., Marianne Klokow, Roswitha Kuhling-Thees, Sonja Loges, MD, Ph.D, Michael Amling, MD, Carsten Bokemeyer, MD, Michael Heuser, MD, Juergen Krauter, MD, Walter Fiedler, MD

Blood (2013) 122 (21): 53.

https://doi.org/10.1182/blood.V122.21.53.53

Published: 2013

Journal Articles

Axl, a prognostic and therapeutic target in acute myeloid leukemia mediates paracrine crosstalk of leukemia cells with bone marrow stroma

Blood (2013) 122 (14): 2443–2452.

https://doi.org/10.1182/blood-2013-03-491431

Published: 2013

Includes: Supplemental data

Journal Articles

Expression of Roundabout Receptor 4 (Robo-4) Confers a Negative Prognosis On Patients with Acute Myeloid Leukemia

Jasmin Wellbrock, Ph.D., Eik Vettorazzi, M.Sc., Gabi Vohwinkel, M.Sc., Thoren Müller, M.D., Marianne Klokow, Carsten Bokemeyer, M.D., Ulrike Bacher, M.D., Jürgen Krauter, MD, PhD, Walter Fiedler, MD

Blood (2012) 120 (21): 1412.

https://doi.org/10.1182/blood.V120.21.1412.1412

Published: 2012

Journal Articles

Circulating Plasma Levels of Bone Morphogenic Protein Antagonist Gremlin-1 Are Increased in Patients with Pulmonary Arterial Hypertension

Jasmin Wellbrock, Ph.D., Jan K. Hennigs, M.D., Björn Schulz, Gabi Vohwinkel, M.Sc., Hans Jörg Baumann, M.D., Carsten Bokemeyer, M.D., Hans Klose, M.D., Walter Fiedler, MD, Nicole Lüneburg, Ph. D.

Blood (2012) 120 (21): 5189.

https://doi.org/10.1182/blood.V120.21.5189.5189

Published: 2012

Journal Articles

CD146: a new partner for VEGFR2

Jasmin Wellbrock, Walter Fiedler

Blood (2012) 120 (11): 2164–2165.

https://doi.org/10.1182/blood-2012-07-439646

Published: 2012

Journal Articles

Gremlin-1 Is Overexpressed in Endothelial Cells of Patients with Loeys-Dietz Syndrome Due to Dysregulation of TGF-β Signalling,

Jasmin Wellbrock, PhD, Sara Sheikhzadeh, MD, Veronika Bonk, Leticia Oliveira-Ferrer, PhD, Kristin Klaetschke, Thomas Streichert, MD, Carsten Bokemeyer, M.D., Yskert von Kodolitsch, MD, Walter Fiedler, M.D.

Blood (2011) 118 (21): 3269.

https://doi.org/10.1182/blood.V118.21.3269.3269

Published: 2011

Journal Articles

Expression of Gli2, a Downstream Mediator of the Activated Hedgehog Pathway, Represents a Negative Prognostic Marker in AML,

Walter Fiedler, M.D., Gabi Vohwinkel, MSc, Juergen Krauter, MD, Eik Vettorazzi, MSc, Sonja Loges, M.D., Ph.D., Livia Fuhrmann, Patrizia Seyfert, Carsten Bokemeyer, M.D., Jasmin Wellbrock, PhD

Blood (2011) 118 (21): 3535.

https://doi.org/10.1182/blood.V118.21.3535.3535

Published: 2011

NARROW

The PTPN2/PTPN1 Inhibitor Abbv-CLS-484 Augments Immune Responses Against Leukemic Blasts and Impedes Leukemia Cell Proliferation in AML Alone and in Combination with Venetoclax

CD39 Is Predominantly Expressed in Adverse AML Patients and Blockade By a New Anti-CD39 Nanobody Increases Lysis of AML Blasts

Loss of SMARCA4 Leads to an Impaired Hematopoiesis in Mice

Blockade of Tigit on AML-Derived M2 Macrophages Results in Reprograming into the M1 Phenotype and Enhances CD47-Mediated Phagocytosis

Increased Frequency of TOX + CD39 + TIGIT + CD73 - CD8 + T Cells in Patients with Newly Diagnosed AML

Mebendazole Mediates Its Anti-Leukemic Effects By Proteasomal Degradation of GLI Transcription Factors Via Inhibition of HSP70/90-Chaperone Activity in Acute Myeloid Leukemia in a Preclinical and Clinical Setting

Mebendazole Exerts Potent Anti-Leukemic Effects By Downregulating Protein Levels of Hedgehog Transcription Factors GLI1 and GLI2

The Actin Binding Protein Plastin-3 Is Involved in the Pathogenesis of Acute Myeloid Leukemia

Expression of Novel Immune Checkpoint Molecules PVR and PVRL2 Confers a Negative Prognosis to Patients with Acute Myeloid Leukemia and Their Blockade Augments T-Cell Mediated Lysis of AML Cells Alone or in Combination with the BiTE ® Antibody Construct AMG 330

Expression Of Hedgehog Pathway Mediator Gli2 Represents a Clinically Negative Prognostic Marker In Acute Myeloid Leukemia and Its Inhibitor GANT61 Exerts Anti-Leukemic Effects In Vitro

Axl, a prognostic and therapeutic target in acute myeloid leukemia mediates paracrine crosstalk of leukemia cells with bone marrow stroma

Expression of Roundabout Receptor 4 (Robo-4) Confers a Negative Prognosis On Patients with Acute Myeloid Leukemia

Circulating Plasma Levels of Bone Morphogenic Protein Antagonist Gremlin-1 Are Increased in Patients with Pulmonary Arterial Hypertension

CD146: a new partner for VEGFR2

Gremlin-1 Is Overexpressed in Endothelial Cells of Patients with Loeys-Dietz Syndrome Due to Dysregulation of TGF-β Signalling,

Expression of Gli2, a Downstream Mediator of the Activated Hedgehog Pathway, Represents a Negative Prognostic Marker in AML,

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American Society of Hematology

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ASH Publications

American Society of Hematology

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