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Journal Articles

BGB324 Inhibits BCR-ABL TKI-Resistant Chronic Myeloid Leukemia

Isabel Ben Batalla, PhD, Robert Erdmann, PhD, Heather Jørgensen, PhD, Rebecca Mitchell, Thomas Ernst, MD, Gunhild von Amsberg, MD, Philippe Schafhausen, MD, Stephen Rankin, MD, Richard E. Clark, Prof MD, Steffen Koschmieder, MD, Alexander Schultze, MD, Subir Mitra, MD, Peter Vandenberghe, Prof MD PhD, Tim H. Brümmendorf, Prof MD, Peter Carmeliet, Prof MD PhD, Gudmundur Helgason, PhD, Andreas Hochhaus, MD, Klaus Pantel, Prof MD PhD, Carsten Bokemeyer, MD, Tessa L Holyoake, Prof PhD, Sonja Loges, MDPhD
Journal: Blood
Blood (2015) 126 (23): 1569.
https://doi.org/10.1182/blood.V126.23.1569.1569
Published: 2015
Journal Articles

BGB324 Represents an Axl and BCR-ABL1 Inhibitor with Activity in the T315I Mutant

Robert Erdmann, PhDMSc, Heather Jorgensen, PhD, Isabel Ben-Batalla, PhD, Nils Kruse, PhD, David Micklem, PhD, Gunhild von Amsberg, MD, Philippe Schafhausen, MD, Alexander Schultze, MD MSc, Mark Wroblewski, MSc, Mascha Binder, Miguel Cubas-Cordova, MSc, Tobias Hadlich, MD, Melanie Janning, MD MSc, Stefanie Sawall, Victoria Gensch, Elaine K Allan, Leena Mukherjee, PhD, Heather Morrison, BSc, Jennifer Cassells, Nicolaus Kroeger, MD, James Lorens, MD, Richard E. Clark, MD, Steffen Koschmieder, MD, Peter Vandenberghe, MD PhD, Tim H. Brümmendorf, MD, Andreas Hochhaus, MD, Peter Carmeliet, MD PhD, Tessa L. Holyoake, MD PhD, Klaus Pantel, MD PhD, Carsten Bokemeyer, MD, Sonja Loges, MD PhD
Journal: Blood
Blood (2014) 124 (21): 4512.
https://doi.org/10.1182/blood.V124.21.4512.4512
Published: 2014
Journal Articles

Axl Represents a Therapeutic Target In T315I-Mutated and WT Chronic Myeloid Leukemia

Robert Erdmann, PhD MSc, Heather Jorgensen, PhD, Alexander Schultze, MD, MSc, Gunhild von Amsberg, MD, Isabel Ben-Battala, PhD, MSc, Mark Wroblewski, MSc, Miguel Cubas Cordova, MSc, Stefanie Sawall, Victoria Witzke, Elaine K Allan, Leena Mukherjee, PhD, Heather Morrison, Jennifer Cassels, Philippe Schafhausen, MD, Nicolaus Kroeger, MD, James Lorens, MD, Richard E. Clark, MBBS, MD, FRCP, FRCPath, Peter Vandenberghe, MD, PhD, Tim H. Brümmendorf, MD, Andreas Hochhaus, MD, Peter Carmeliet, MD, PhD, Klaus Pantel, MD, PhD, Carsten Bokemeyer, MD, Tessa L. Holyoake, PhD, FRCP, FRCPath, Sonja Loges, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 1469.
https://doi.org/10.1182/blood.V122.21.1469.1469
Published: 2013
Journal Articles

Axl, a prognostic and therapeutic target in acute myeloid leukemia mediates paracrine crosstalk of leukemia cells with bone marrow stroma

Isabel Ben-Batalla, Alexander Schultze, Mark Wroblewski, Robert Erdmann, Michael Heuser, Jonas S. Waizenegger, Kristoffer Riecken, Mascha Binder, Denis Schewe, Stefanie Sawall, Victoria Witzke, Miguel Cubas-Cordova, Melanie Janning, Jasmin Wellbrock, Boris Fehse, Christian Hagel, Jürgen Krauter, Arnold Ganser, James B. Lorens, Walter Fiedler, Peter Carmeliet, Klaus Pantel, Carsten Bokemeyer, Sonja Loges
Journal: Blood
Blood (2013) 122 (14): 2443–2452.
https://doi.org/10.1182/blood-2013-03-491431
Published: 2013
Includes: Supplemental data
Journal Articles

Prognostic Significance and Target Potential of Axl in Acute Myeloid Leukemia

Alexander Schultze, M.D., M.Sc., Isabel Ben-Batalla, Ph.D., Michael Heuser, M.D., Kristoffer Weber, Ph.D., Robert Erdmann, Ph.D., Sacha Holland, Ph.D., Stefanie Sawall, Helena Fritz, M.Sc., Marc Tjwa, M.D., Ph.D., Thomas Schmidt, M.D., Walter Fiedler, M.D., Boris Fehse, Ph.D., Bjorn Dahlback, M.D., Klaus Pantel, M.D., Ph.D., Jürgen Krauter, Arnold Ganser, MD, Carsten Bokemeyer, M.D., Sonja Loges, M.D., Ph.D.
Journal: Blood
Blood (2011) 118 (21): 940.
https://doi.org/10.1182/blood.V118.21.940.940
Published: 2011
Journal Articles

Expression of TGF-β Superfamily Receptor ALK-5 Is Associated with Decreased Overall Survival of AML Patients Receiving Standard AML Chemotherapy.

Jasmin Otten, MSc, Lisa Schmitz, Eik Vettorazzi, MSc, Alexander Schultze, MSc, Jürgen Krauter, MD, Carsten Bokemeyer, MD, Walter Fiedler, MD
Journal: Blood
Blood (2009) 114 (22): 1604.
https://doi.org/10.1182/blood.V114.22.1604.1604
Published: 2009