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Journal Articles

Clonal Dynamics of Normal Haematopoiesis with Human Ageing

Emily Mitchell, Michael Spencer Chapman, Nicholas Williams, Kevin J Dawson, Nicole Mende, Emily Calderbank, Hyunchul Jung, Thomas J Mitchell, Tim Coorens, David Spencer, Heather E Machado, Henry Lee-Six, Megan Davies, Daniel Hayler, Margarete Alice Fabre, Krishnaa Mahbubani, Federico Abascal, George S. Vassiliou, Joanna E Baxter, Inigo Martincorena, Michael Stratton, David G. Kent, Krishna Chatterjee, Kourosh Saeb-Parsy, Anthony R Green, Jyoti Nangalia, Elisa Laurenti, Peter J. Campbell
Journal: Blood
Blood (2021) 138 (Supplement 1): 598.
https://doi.org/10.1182/blood-2021-150152
Published: 2021
Journal Articles

DNMT3A -Dependent DNA Methylation May Act As a Tumor Suppressor-Not a Tumor Promoter-during AML Progression

David Spencer, MDPhD, David Russler-Germain, Nichole M Helton, B.S., Tamara L Lamprecht, B.S., Marwan Shinawi, MD, Peter Westervelt, MD PhD, Jacqueline E. Payton, MD PhD, Robert S. Fulton, PhD, Richard K Wilson, PhD, Matthew J. Walter, MD, Daniel C. Link, MD, John F. DiPersio, MD, PhD, Timothy J. Ley, MD
Journal: Blood
Blood (2016) 128 (22): 1050.
https://doi.org/10.1182/blood.V128.22.1050.1050
Published: 2016
Journal Articles

Reprogramming of Leukemic and Pre-Leukemic Cells from Primary Human De Novo Acute Myeloid Leukemia Samples into Induced Pluripotent Stem (iPS) Cells

David Spencer, MDPhD, Daniel R. George, Jeffery M. Klco, MDPhD, Timothy J. Ley, MD
Journal: Blood
Blood (2015) 126 (23): 1862.
https://doi.org/10.1182/blood.V126.23.1862.1862
Published: 2015
Journal Articles

Characterization of snoRNA Expression in Acute Myeloid Leukemia

Wayne A. Warner, BS, David Spencer, MDPhD, Maria Trissal, BS, Nichole Helton, BS, Timothy J. Ley, MD, Daniel C. Link, MD
Journal: Blood
Blood (2015) 126 (23): 3649.
https://doi.org/10.1182/blood.V126.23.3649.3649
Published: 2015
Journal Articles

Specific Patterns of DNA Remethylation in the Bone Marrow Cells of Dnmt3a Deficient Mice after Induced Expression of Wild Type Human DNMT3A

Shamika Ketkar-Kulkarni, Angela Maria Verdoni, PhD, Nichole Helton, Christopher B Cole, Celia Venezia, Mieke Hoock, Catrina Fronick, Michelle O'Laughlin, Robert S. Fulton, PhD, David Spencer, MDPhD, Timothy J. Ley, MD
Journal: Blood
Blood (2015) 126 (23): 433.
https://doi.org/10.1182/blood.V126.23.433.433
Published: 2015
Journal Articles

Inducible MyD88/CD40 Allows AP1903-Dependent Costimulation to Control Proliferation and Survival of Chimeric Antigen Receptor-Modified T Cells

Aaron Foster, PhD, Aruna Mahendravada, Peter Chang, PhD, Nicholas Shinners, PhD, Kevin Slawin, MD, David Spencer, PhD
Journal: Blood
Blood (2014) 124 (21): 1121.
https://doi.org/10.1182/blood.V124.21.1121.1121
Published: 2014
Journal Articles

T-Cells Redirected Against CD70 for the Immunotherapy of Hematological Malignancies.

Donald Shaffer, MS, Barbara Savoldo, MD, Gianpietro Dotti, MD, David Spencer, PhD, Shannon Kenney, MD, Cliona M. Rooney, PhD, Stephen Gottschalk, MD
Journal: Blood
Blood (2007) 110 (11): 2757.
https://doi.org/10.1182/blood.V110.11.2757.2757
Published: 2007