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Nichole Helton
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Journal Articles

Rapid and Accurate Remethylation of Dnmt3a Deficient Hematopoietic Cells with Restoration of DNMT3A Activity

Yang Li, Haley Abel, Michelle Cai, Taylor Lavalle, Tiankai Yin, Nichole Helton, Amanda Smith, Christopher A Miller, Timothy J Ley
Journal: Blood
Blood (2023) 142 (Supplement 1): 4124.
https://doi.org/10.1182/blood-2023-180255
Published: 2023
Journal Articles

Overexpression of the Signaling Integrator Gab2 Accelerates AML Development in Mice with Dnmt3a R878H and Npm1 cA Mutations

Michael H. Kramer, Stephanie Richardson, Yang Li, Nichole Helton, Daniel George, Michelle Cai, Sai Mukund Ramakrishnan, Christopher A Miller, Timothy J Ley
Journal: Blood
Blood (2023) 142 (Supplement 1): 2752.
https://doi.org/10.1182/blood-2023-175053
Published: 2023
Journal Articles

Mechanisms of PML::Rara and GATA2 Protein Interactions in Hematopoietic Cells

Casey Katerndahl, Olivia Rogers, Nichole Helton, Sai Mukund Ramakrishnan, Christopher A Miller, Ziheng Xu, Sridhar N Srivatsan, Timothy J Ley
Journal: Blood
Blood (2023) 142 (Supplement 1): 2758.
https://doi.org/10.1182/blood-2023-181291
Published: 2023
Journal Articles

The Molecular Basis of Long First Remissions in Normal Karyotype AML Patients

Francesca Ferraro, MD PhD, Christopher A Miller, PhD, Amy Abdalla, Nichole Helton, Nathan Salomonis, PhD, Robert S Fulton, Catrina Fronick, BS, Sharon E Heath, Peter Westervelt, MD PhD, Timothy J Ley, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3827.
https://doi.org/10.1182/blood-2019-122967
Published: 2019
Journal Articles

Whole Genome Bisulfite Sequencing of 63 Primary AML Samples Identifies a Unique DNA Hypermethylation Signature for Mutant IDH1/2 Cases That Is Different from That of TET2 Mutant AML

Ellie Wilson, BS, Nichole Helton, Catrina Fronick, BS, Robert Fulton, MS, John S. Welch, MD PhD, Timothy J Ley, MD, David H Spencer, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3755.
https://doi.org/10.1182/blood-2019-122340
Published: 2019
Journal Articles

Evidence for Complete Mutation Clearance in Normal Karyotype AML Patients with Very Long (> 5 years) Remissions after Chemotherapy Alone

Francesca Ferraro, MD PhD, Christopher A Miller, PhD, Nichole Helton, Robert S Fulton, Catrina Fronick, BS, Sharon E Heath, Peter Westervelt, MD PhD, Timothy J Ley, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1503.
https://doi.org/10.1182/blood-2018-99-117288
Published: 2018
Journal Articles

Characterization of snoRNA Expression in Acute Myeloid Leukemia

Wayne A. Warner, BS, David Spencer, MDPhD, Maria Trissal, BS, Nichole Helton, BS, Timothy J. Ley, MD, Daniel C. Link, MD
Journal: Blood
Blood (2015) 126 (23): 3649.
https://doi.org/10.1182/blood.V126.23.3649.3649
Published: 2015
Journal Articles

Specific Patterns of DNA Remethylation in the Bone Marrow Cells of Dnmt3a Deficient Mice after Induced Expression of Wild Type Human DNMT3A

Shamika Ketkar-Kulkarni, Angela Maria Verdoni, PhD, Nichole Helton, Christopher B Cole, Celia Venezia, Mieke Hoock, Catrina Fronick, Michelle O'Laughlin, Robert S. Fulton, PhD, David Spencer, MDPhD, Timothy J. Ley, MD
Journal: Blood
Blood (2015) 126 (23): 433.
https://doi.org/10.1182/blood.V126.23.433.433
Published: 2015