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Sai Mukund Ramakrishnan
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Journal Articles

Reduced CBFB Expression Causes Compensatory Upregulation of RUNX1 Expression, Defining a Feedback Loop That May be Relevant for AML Pathogenesis

Ryan B. Day, Sai Mukund Ramakrishnan, Christopher A Miller, Timothy J Ley
Journal: Blood
Blood (2024) 144 (Supplement 1): 4107.
https://doi.org/10.1182/blood-2024-207713
Published: 2024
Journal Articles

VISTA As a Mediator of Immune Suppression in AML Initiated By DNMT3A and NPM1 mutations

Tiankai Yin, Michael H. Kramer, Michael Bern, Nichole Helton, Daniel George, Mieke Hoock, Sai Mukund Ramakrishnan, Christopher A Miller, Timothy J Ley
Journal: Blood
Blood (2024) 144 (Supplement 1): 4100.
https://doi.org/10.1182/blood-2024-206063
Published: 2024
Journal Articles

Recurrent Amplification of Chromosome 7 in Murine AML with Dnmt3a R878H and Npm1 cA Mutations Identifies Gab2 As a Possible Therapeutic Target in AML

Michael H. Kramer, Stephanie N Richardson, Yang Li, Tiankai Yin, Nichole Helton, Daniel George, Michelle Cai, Sai Mukund Ramakrishnan, Christopher A Miller, Timothy J Ley
Journal: Blood
Blood (2024) 144 (Supplement 1): 1333.
https://doi.org/10.1182/blood-2024-199837
Published: 2024
Journal Articles

Overexpression of the Signaling Integrator Gab2 Accelerates AML Development in Mice with Dnmt3a R878H and Npm1 cA Mutations

Michael H. Kramer, Stephanie Richardson, Yang Li, Nichole Helton, Daniel George, Michelle Cai, Sai Mukund Ramakrishnan, Christopher A Miller, Timothy J Ley
Journal: Blood
Blood (2023) 142 (Supplement 1): 2752.
https://doi.org/10.1182/blood-2023-175053
Published: 2023
Journal Articles

Mechanisms of PML::Rara and GATA2 Protein Interactions in Hematopoietic Cells

Casey Katerndahl, Olivia Rogers, Nichole Helton, Sai Mukund Ramakrishnan, Christopher A Miller, Ziheng Xu, Sridhar N Srivatsan, Timothy J Ley
Journal: Blood
Blood (2023) 142 (Supplement 1): 2758.
https://doi.org/10.1182/blood-2023-181291
Published: 2023
Journal Articles

Nucleolar Stress Plays a Key Role in the Pathogenesis of T Cell Acute Lymphoblastic Leukemia

Joseph R. Krambs, Kimberly B. Johansson, Isabelle Genter, Sai Mukund Ramakrishnan, Christopher A Miller, Daniel C. Link
Journal: Blood
Blood (2022) 140 (Supplement 1): 5891–5892.
https://doi.org/10.1182/blood-2022-158717
Published: 2022
Journal Articles

A Comprehensive Reassessment of the Direct DNA Binding Sites of PML-Rara within the Genomes of Primary Hematopoietic Progenitor Cells, and Their Effects on Chromatin Structure and Gene Expression

Casey D.S. Katerndahl, Olivia R.S. Rogers, Sai Mukund Ramakrishnan, Christopher A Miller, Nichole M Helton, Mieke Hoock, Timothy J Ley
Journal: Blood
Blood (2022) 140 (Supplement 1): 5858–5859.
https://doi.org/10.1182/blood-2022-167204
Published: 2022
Journal Articles

Re-Sensitization of Allogeneic T Cell Resistant Murine AML with Pegylated IFN-Gamma

Ezhilarasi Chendamarai, Julie K. Ritchey, Leah Gehrs, Michael P. Rettig, Sai Mukund Ramakrishnan, Christopher A Miller, George Cox, Lana Anderson, Timothy J Ley, John F. DiPersio
Journal: Blood
Blood (2022) 140 (Supplement 1): 7345–7346.
https://doi.org/10.1182/blood-2022-167415
Published: 2022
Journal Articles

Dnmt3a Inactivation Leads to Slow DNA Methylation Loss in Murine Hematopoietic Cells In Vivo

Amanda M Smith, Angela Maria Verdoni, Shamika Ketkar, Elizabeth Leight, David Y Chen, Sai Mukund Ramakrishnan, Christopher A Miller, Haley J Abel, Timothy J Ley
Journal: Blood
Blood (2021) 138 (Supplement 1): 1087.
https://doi.org/10.1182/blood-2021-150558
Published: 2021
Journal Articles

Adverse Outcomes in Acute Myeloid Leukemia Are Associated with Tumor Cell-Mediated Immunosuppression

Francesca Ferraro, Christopher A Miller, Keegan A Christensen, Nichole M Helton, Michelle O'Laughlin, Robert Fulton, Jessica Kohlschmidt, Ann-Kathrin Eisfeld, Bloomfield Clara, Sai Mukund Ramakrishnan, Lukas D Wartman, John Welch, Matthew Christopher, Sharon E Heath, Peter Westervelt, Jack D Baty, Jacqueline E. Payton, Michael Retting, Daniel C. Link, Matthew J. Walter, John F. DiPersio, Ryan Day, Geoffrey L. Uy, Matthew Schuelke, David H Spencer, Timothy J Ley
Journal: Blood
Blood (2021) 138 (Supplement 1): 800.
https://doi.org/10.1182/blood-2021-148645
Published: 2021
Journal Articles

Tumor suppressor function of Gata2 in acute promyelocytic leukemia

Casey D. S. Katerndahl, Olivia R. S. Rogers, Ryan B. Day, Michelle A. Cai, Timothy P. Rooney, Nichole M. Helton, Mieke Hoock, Sai Mukund Ramakrishnan, Sridhar Nonavinkere Srivatsan, Lukas D. Wartman, Christopher A. Miller, Timothy J. Ley
Journal: Blood
Blood (2021) 138 (13): 1148–1161.
https://doi.org/10.1182/blood.2021011758
Published: 2021
Includes: Supplemental data
Journal Articles

Gata2 Expression and Function in PML-RARA- driven Preleukemia and APL

Casey D.S. Katerndahl, PhD, Timothy J Ley, MD, Michelle A Cai, Timothy P Rooney, Jr., Sai Mukund Ramakrishnan, MS, Sridhar Nonavinkere Srivatsan, MS, Christopher A Miller, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 534.
https://doi.org/10.1182/blood-2019-131883
Published: 2019
Journal Articles

DNMT3A R882 Alters the Epigenome of Hematopoietic Cells

Amanda M Smith, PhD, Taylor LaValle, BS, Shamika Ketkar, PhD, Sai Mukund Ramakrishnan, MS, Christopher A Miller, PhD, Timothy J Ley, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 112.
https://doi.org/10.1182/blood-2019-129003
Published: 2019