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Journal Articles

Arginine Methylation of BRD4 By CARM1 Regulates Its Function in AML

Adnan K. Mookhtiar, Hidehiro Itonaga, Sarah Greenblatt, Concepcion Martinez, Jun Sun, Krystal Lisa Hossack, Ramin Shiekhattar, Daniel Bilbao, Maria Ken E. Figueroa, Simone Sidoli, Stephen D. Nimer
Journal: Blood
Blood (2023) 142 (Supplement 1): 4112.
https://doi.org/10.1182/blood-2023-189759
Published: 2023
Journal Articles

Tyrosine Phosphorylation of CARM1 Promotes Its Enzymatic Activity and Alters Its Target Specificity in Myeloid Neoplasms with Hyperactivated JAK2

Hidehiro Itonaga, Adnan K Mookhtiar, Sarah Greenblatt, Fan Liu, Concepcion Martinez, Renata Grozovsky, Daniel Bilbao, Masai Rains, Pierre-Jacques Hamard, Jun Sun, Afoma Umeano, Stephanie Duffort, Chuan Chen, Na Man, Gloria Mas Martin, Stephen Schürer, Stephen D Nimer
Journal: Blood
Blood (2022) 140 (Supplement 1): 3021–3022.
https://doi.org/10.1182/blood-2022-156887
Published: 2022
Journal Articles

The NLRC4 Inflammasome Drives Myelodysplastic Syndrome By Linking Epigenetic Reprogramming and Innate Immune Signaling

Chuan Chen, Na Man, Francesco Tamiro, Krystal Hossack, Julio Poveda, Daniel Bilbao, Gloria Mas, Stephanie Duffort, Concepcion Martinez, Hidehiro Itonaga, Fan Liu, Jennifer R Chapman-Fredricks, Stephen D Nimer
Journal: Blood
Blood (2022) 140 (Supplement 1): 3009–3010.
https://doi.org/10.1182/blood-2022-160075
Published: 2022
Journal Articles

The Baf Subunit Dpf2 Regulates Resolution of Inflammation By Controlling Macrophage Differentiation Transcription Factor Networks

Gloria Mas Martin, PhD, Na Man, Daniel Karl, PhD, Concepcion Martinez, B.S., Stephanie Duffort, Hidehiro Itonaga, MD PhD, Adnan K Mookhtiar, BS, Daniel Bilbao, PhD, Kranthi Kunkalla, Alfredo M Valencia, Clayton Collings, Cigall Kadoch, PhD, Francisco Vega, MDPhD, Scott C. Kogan, MD, Stephen Nimer, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 13.
https://doi.org/10.1182/blood-2020-142030
Published: 2020
Journal Articles

EP300 Suppresses Leukemia Development in Myelodysplastic Syndrome through Myb Repression

Na Man, Gloria Mas Martin, PhD, Daniel Karl, PhD, Jun Sun, PhD, Fan Liu, PhD, Miguel Torres-Martin, PhD, Hidehiro Itonaga, MD PhD, Concepcion Martinez, B.S., Shi Chen, Stephanie Duffort, Pierre-Jacques Hamard, PhD, Ye Xu, PhD, Luisa Cimmino, PhDBSc, Feng-Chun Yang, MD PhD, Philip A. Cole, MD PhD, Mingjiang Xu, MD PhD, Maria E. Figueroa, MD, Stephen Nimer, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 561.
https://doi.org/10.1182/blood-2019-130507
Published: 2019
Journal Articles

PRMT5 Regulates DNA Repair By Controlling the Alternative Splicing of Epigenetic Factors

Pierre-Jacques Hamard, PhD, Gabriel Emmanuel Santiago, Fan Liu, PhD, Sarah Greenblatt, PhD, Daniel Karl, PhD, Concepcion Martinez, B.S., Ramiro E Verdun, PhD, Stephen D. Nimer, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1148.
https://doi.org/10.1182/blood.V130.Suppl_1.1148.1148
Published: 2017
Journal Articles

CARM1/PRMT4 As a Novel Therapeutic Target for AML

Sarah Greenblatt, PhD, Na Man, Pierre-Jacques Hamard, PhD, Concepcion Martinez, B.S., Ye Xu, PhD, Fan Liu, PhD, Justin M Watts, MD, Daniel G. Tenen, MD, Stephen D. Nimer, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 241.
https://doi.org/10.1182/blood.V130.Suppl_1.241.241
Published: 2017
Journal Articles

The AML-Associated FLT3-ITD Kinase Regulates Histone Modifications and Cytokine Signaling, Via Effects on PRMT5

Koji Ando, MD PhD, Pierre-Jacques Hamard, PhD, Fan Liu, PhD, Concepcion Martinez, Yuguang Ban, PhD, Xi Chen, PhD, Stephen D. Nimer, MD
Journal: Blood
Blood (2016) 128 (22): 2696.
https://doi.org/10.1182/blood.V128.22.2696.2696
Published: 2016
Journal Articles

TAFII250 Is Critical in AML1-ETO Mediated Leukemogenesis

Ye Xu, PhD, Na Man, PhD, Concepcion Martinez, Camilo Martinez, Felipe Beckedorf, Guoyan Cheng, PhD, Sarah Merin Greenblatt, PhD, Lan Wang, PhD, Ramin Shiekhattar, Stephen D. Nimer, MD
Journal: Blood
Blood (2016) 128 (22): 1520.
https://doi.org/10.1182/blood.V128.22.1520.1520
Published: 2016