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Ramya Goparaju
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Journal Articles

Signaling Pathways of Mutant IDH1 Independent of R-2-Hydroxyglutarate

Charu Gupta, Michelle Maria Araujo Cruz, PhD, Nidhi Jyotsana, PhD, Amit Sharma, PhD, Ramya Goparaju, PhD, Kerstin Görlich, Renate Schottmann, Eduard Struys, PhD, Erwin E Jansen, Felicitas Thol, MD, Arnold Ganser, MD, Michael Heuser, MD, Anuhar Chaturvedi, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2617.
https://doi.org/10.1182/blood-2018-99-110159
Published: 2018
Journal Articles

Prolyl Hydroxylase 3 (Phd3) Is a Therapeutic Target in Isocitrate Dehydrogenase 1 (IDH1) Mutated Acute Myeloid Leukemia

Anuhar Chaturvedi, PhD, Michelle Maria Araujo Cruz, PhD, Ramya Goparaju, PhD, Razif Gabdoulline, Renate Schottmann, Kerstin Görlich, Arnold Kloos, Felicitas Thol, MD, Robert Geffers, PhD, Dimitrios Mougiakakos, Peter Carmeliet, MD PhD, Arnold Ganser, MD, Michael Heuser, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 759.
https://doi.org/10.1182/blood-2018-99-110425
Published: 2018
Journal Articles

Synergistic Activity of IDH1 Inhibitor Bay-1436032 with Azacitidine in IDH1 Mutant Acute Myeloid Leukemia

Anuhar Chaturvedi, PhD, Charu Gupta, Ramya Goparaju, Razif Gabdoulline, PhD, Stefan Kaulfuss, PhD, Kerstin Görlich, Renate Schottmann, Olaf Panknin, Markus Wagner, PhD, Robert Geffers, PhD, Arnold Ganser, MD, Felicitas Thol, MD, Michael Jeffers, PhD, Andrea Haegebarth, Michael Heuser, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1352.
https://doi.org/10.1182/blood.V130.Suppl_1.1352.1352
Published: 2017
Journal Articles

Pan-Mutant-IDH1 Inhibitor Bay-1436032 Is Highly Effective Against Human IDH1 Mutant Acute Myeloid Leukemia In Vivo

Michael Heuser, MD, Lena Herbst, PhD, Stefan Pusch, Lara Klett, Ramya Goparaju, Damian Stichel, Stefan Kaulfuss, Olaf Panknin, Katja Zimmermann, Luisella Toschi, Roland Neuhaus, Andrea Haegebarth, Hartmut Rehwinkel, Holger Hess-Stumpp, Markus Bauser, Tilmann Bochtler, MD, Eduard A Struys, Amit Sharma, PhD MSc, BSc, Abdellatif Abdellatif, Robert Geffers, PhD, Michelle M Araujo Cruz, Felicitas Thol, MD, Razif Gabdoulline, Arnold Ganser, MD, Anthony D Ho, MD, Andreas von Deimling, Karsten Rippe, Anuhar Chaturvedi, PhD MS, BPharm, Alwin Kraemer, MD
Journal: Blood
Blood (2016) 128 (22): 745.
https://doi.org/10.1182/blood.V128.22.745.745
Published: 2016
Journal Articles

A Novel Inhibitor of Mutant IDH1 Induces Differentiation in Vivo and Prolongs Survival in a Mouse Model of Leukemia

Anuhar Chaturvedi, PhD, Michelle Maria Araujo Cruz, Ramya Goparaju, Nidhi Jyotsana, Heike Baehre, PhD, Kerstin Goerlich, Renate Schottmann, Matthias Preller, PhD, Eduard A. Struys, PhD, Arnold Kloos, PhD, Volkhard Kaever, PhD, Arnold Ganser, Felicitas Thol, MD, Michael Heuser, MD
Journal: Blood
Blood (2014) 124 (21): 3598.
https://doi.org/10.1182/blood.V124.21.3598.3598
Published: 2014
Journal Articles

The Metabolite R-2-Hydroxyglutarate (R2HG) Collaborates with HoxA9 to Induce Monocytic Leukemia

Anuhar Chaturvedi, PhD, Michelle Maria Araujo Cruz, Nidhi Jyotsana, Amit Sharma, PhD, Ramya Goparaju, Vishwas Sharma, PhD, Adrian Schwarzer, MDPhD, Kerstin Goerlich, Renate Schottmann, Eduard A. Struys, PhD, Erwin E. Jansen, Robert Geffers, PhD, Gudrun Goehring, MD, Felicitas Thol, MD, Arnold Ganser, Michael Heuser, MD
Journal: Blood
Blood (2014) 124 (21): 366.
https://doi.org/10.1182/blood.V124.21.366.366
Published: 2014