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Journal Articles

Inactivation of TP53 correlates with disease progression and low miR-34a expression in previously treated chronic lymphocytic leukemia patients

Annika Dufour, Giuseppe Palermo, Evelyn Zellmeier, Gudrun Mellert, Guillemette Duchateau-Nguyen, Stephanie Schneider, Tobias Benthaus, Purvi M. Kakadia, Karsten Spiekermann, Wolfgang Hiddemann, Jan Braess, Sim Truong, Nancy Patten, Lin Wu, Sabine Lohmann, David Dornan, Debraj GuhaThakurta, Ru-Fang Yeh, Galina Salogub, Philippe Solal-Celigny, Anna Dmoszynska, Tadeusz Robak, Marco Montillo, John Catalano, Christian H. Geisler, Martin Weisser, Stefan K. Bohlander
Journal: Blood
Blood (2013) 121 (18): 3650–3657.
https://doi.org/10.1182/blood-2012-10-458695
Published: 2013
Includes: Supplemental data
Journal Articles

Mutational Analysis of TP53 Gene in Chronic Lymphocytic Leukemia: Comparison of Different Methodological Approaches

Barbara Kantorova, MSc., Jitka Malcikova, Dr., PhD., Jana Kminkova, PharmD., Veronika Navrkalova, MSc., Barbora Dvorakova, MSc., Boris Tichy, Dr., PhD., Jana Smardova, Prof., Martin Trbusek, Dr., PhD., Sim Truong, PhD., Katerina Stano-Kozubik, PhD., Nikola Tom, MSc., Karol Pal, MSc., Ludmila Sebejova, Dr., Nancy Patten, PhD., Lin Wu, PhD., Michael Doubek, M.D., PhD., Prof., Jiri Mayer, M.D., PhD., Prof., Sarka Pospisilova, Dr., PhD., Prof.
Journal: Blood
Blood (2012) 120 (21): 3911.
https://doi.org/10.1182/blood.V120.21.3911.3911
Published: 2012
Journal Articles

Disruption of TP53 function by Point Mutations and Deletions Is Associated with An Increased Risk of Disease Progression within Previously Treated, Relapsed Chronic Lymphocytic Leukemia Patients

Annika Dufour, Stefan K Bohlander, Evelyn Zellmeier, Gudrun Mellert, Karsten Spiekermann, MD, Stephanie Schneider, PhD, Purvi Kakadia, Wolfgang Hiddemann, PhD, Jan Braess, Sim Truong, Nancy Patten, Lin Wu, Galina Salogub, Philippe Solal-Celigny, Anna Dmoszynska, Tadeusz Robak, Boris V Afanasiev, Marco Montillo, John Catalano, MBBS FRACP FRCPA, Christian H. Geisler, David Dornan, Ming Lin, Ru-Fang Yeh, Martin Weisser, Guillemette Duchateau-Nguyen, Giuseppe Palermo
Journal: Blood
Blood (2011) 118 (21): 2445.
https://doi.org/10.1182/blood.V118.21.2445.2445
Published: 2011
Journal Articles

Low Expression of MiR-34a in Previously Treated Chronic Lymphocytic Leukemia Patients Is Limited to Patients with a Complete Disruption of TP53 Function and Does Not Correlate with MDM2 SNP309,

Annika Dufour, PhD, Stefan K Bohlander, Evelyn Zellmeier, Gudrun Mellert, Karsten Spiekermann, MD, Stephanie Schneider, PhD, Purvi Kakadia, Wolfgang Hiddemann, PhD, Jan Braess, Sim Truong, Nancy Patten, Lin Wu, Galina Salogub, Philippe Solal-Celigny, Anna Dmoszynska, Tadeusz Robak, Boris V Afanasiev, Marco Montillo, John Catalano, MBBS FRACP FRCPA, Christian H. Geisler, David Dornan, Ming Lin, Ru-Fang Yeh, Martin Weisser, Guillemette Duchateau-Nguyen, Giuseppe Palermo
Journal: Blood
Blood (2011) 118 (21): 3521.
https://doi.org/10.1182/blood.V118.21.3521.3521
Published: 2011
Journal Articles

TP53 Mutations and Outcome After Fludarabine and Cyclophosphamide (FC) or FC Plus Rituximab (FCR) in the CLL8 Trial of the GCLLSG.

Thorsten Zenz, Patrick Hoth, Raymonde Busch, Hanne Helfrich, Dirk Winkler, Andreas Bühler, Nancy Patten, Sim Truong, Lin Wu, Günther Fingerle-Rowson, Kirsten Fischer, Anna-Maria Fink, Ulrich Jäger, Sebastian Böttcher, Michael Kneba, Michael K. Wenger, Myriam Mendila, Michael Hallek, Hartmut Döhner, Stephan Stilgenbauer
Journal: Blood
Blood (2009) 114 (22): 1267.
https://doi.org/10.1182/blood.V114.22.1267.1267
Published: 2009
Journal Articles

Clinical Impact of TP53 Gene Mutations in Diffuse Large B-Cell Lymphoma (DLBCL): An International DLBCL Rituxan-CHOP Consortium Program Study.

Ken H. Young, MD, PhD, Nancy Patten, PhD, Sim Truong, PhD, Jens Eickhoff, PhD, Gabrielle L. Rocque, MD, Jeffrey T. Malik, MD, Yan Li, PhD, Kazunori Kanehira, MD, PhD, Matthew Twohig, MD, William M. Rehrauer, PhD, Michelle A. Waknitz, MS, Brad S. Kahl, MD, Michael B. Moller, MD, PhD, Alexander Tzankov, PhD, Santiago M. Moreno, MD, Miguel A. Piris, MD, Carlo Visco, MD, Karen Dybkaer, PhD, April Chiu, MD, Attilio Orazi, MD, Jeff C. Chang, MD, PhD, Govind Bhagat, MD, Jane N. Winter, MD, Huan-You Wang, MD, PhD, Cherie Dunphy, MD, Stacey O'Neill, MD, PhD, Eric D. Hsi, MD, Xianfeng Zhao, MD, PhD, Kristin Hunt, MD, Weina Chen, MD, PhD, Ronald S. Go, MD, William W.L. Choi, MD, Fan Zhou, MD, PhD, Magdalena Czader, MD, PhD, Yong Li, PhD, Suzanne Selvaggi, MD, James S. Malter, MD, Lin Wu, PhD
Journal: Blood
Blood (2009) 114 (22): 967.
https://doi.org/10.1182/blood.V114.22.967.967
Published: 2009
Journal Articles

TP53 Abnormalities in Chronic Lymphocytic Leukemia Exhibit a Disease Specific Profile: Meta-Analysis of 270 Mutations.

Thorsten Zenz, Jana Smadova, Dominik Vollmer, Martin Trbusek, Axel Benner, Sonja Häbe, Tina Denzel, Jitka Malcikova, Sim Truong, Nancy Patten, David Oscier, Rachel Ibbotson, Anne Gardiner, Ian Tracy, Ke Lin, Andrew Pettitt, Sarka Popsilova, Jiri Mayer, Hartmut Döhner, Stephan Stilgenbauer
Journal: Blood
Blood (2008) 112 (11): 2077.
https://doi.org/10.1182/blood.V112.11.2077.2077
Published: 2008
Journal Articles

17p Deletion in CLL: Detailed Analysis of TP53 Mutations, Alternative Mechanisms of p53 Inactivation, Clone Size and Clonal Evolution

Thorsten Zenz, Antonio Sarno, Sonja Häbe, Tina Denzel, Julia Mohr, Dominik Vollmer, Maria Heuberger, Dirk Winkler, Dirk Kienle, Andreas Bühler, Sim Truong, Nancy Patten, Michael Hallek, Hartmut Döhner, Stephan Stilgenbauer
Journal: Blood
Blood (2008) 112 (11): 782.
https://doi.org/10.1182/blood.V112.11.782.782
Published: 2008
Journal Articles

High Frequency of P53 Mutations Detected by a Microarray Resequencing Assay, the AmpliChip P53 Test, in AML with a Complex Aberrant Karyotype.

Nancy Patten, Sim Truong, Jeff Fu, Frank Dicker, Ph.D., Susanne Schnittger, Ph.D., Wolfgang Kern, MD, Alexander Kohlmann, Ph.D., Torsten Haferlach, MD, Claudia Schoch, MD, Lin Wu, Ph.D.
Journal: Blood
Blood (2006) 108 (11): 4341.
https://doi.org/10.1182/blood.V108.11.4341.4341
Published: 2006
Journal Articles

Strong p53 Expression Is an Independent Predictor of Outcome in De Novo Diffuse Large B Cell Lymphoma (DLBCL) Treated with Either CHOP or CHOP-R.

Pedro Farinha, MD, Laurie Sehn, MD, Brian Skinnider, MD, Lin Wu, Nancy Patten, Sim Truong, Joseph M. Connors, MD, Randy D. Gascoyne, MD
Journal: Blood
Blood (2006) 108 (11): 812.
https://doi.org/10.1182/blood.V108.11.812.812
Published: 2006