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Journal Articles

Treatment Guided By Next Generation Functional Drug Screening Provides Clinical Benefit in Advanced Aggressive Hematological Malignancies: Final Evaluation of the Open Label, Single Arm Exalt Trial

Christoph Kornauth, Tea Pemovska, PhDMSc,BSc, Gregory Ian Vladimer, PhD, Günther Bayer, Michael Bergmann, Sandra Eder, Ruth Eichner, Harald Esterbauer, MD PhD, Ruth Exner, Verena Felsleitner-Hauer, Maurizio Forte, MSc, Alexander Gaiger, Hildegard T. Greinix, MD, Wolfgang Gstöttner, Marcus Hacker, Alexander Hauswirth, MD, Tim Heinemann, Daniel Heintel, Mir Ali Reza Hoda, Ulrich Jaeger, Lukas Kazianka, MD, Lukas Kenner, MD, Barbara Kiesewetter, MD, Nikolaus Krall, PhD, Trang Le, BSc, Simone Lubowitzki, Marius E Mayerhoefer, Elisabeth Menschel, Olaf Merkel, PhD, Katsuhiro Miura, MD PhD, Leonhard Muellauer, MD PhD, Peter Neumeister, MD, Thomas Noesslinger, MD, Katharina Ocko, Leopold Öhler, Michael Panny, MD, Alexander Pichler, MD, Edit Anna Porpaczy, MD, Gerald Prager, MD, Markus Raderer, Robin Ristl, Reinhard Ruckser, MD, Julius Salamon, Ana-Iris Schiefer, Ann-Sofie Schmolke, MD, Ilse Schwarzinger, MD, Edgar Selzer, Cathrin Skrabs, Wolfgang R. Sperr, MD, Ismet Srndic, MSc, Renate Thalhammer, MD, Peter Valent, MD, Emiel van der Kouwe, PharmD, Katrina Vanura, PhD, Stefan Vogt, Cora Waldstein, Dominik Wolf, Univ. Prof. Dr., Christoph Zielinski, Ingrid Simonitsch-Klupp, MD, Giulio Superti-Furga, PhD, Berend Snijder, PhD, Philipp B. Staber, MD PhD

Blood (2020) 136 (Supplement 1): 2–4.

https://doi.org/10.1182/blood-2020-140831

Published: 2020

Journal Articles

Overexpression of uridine diphospho glucuronosyltransferase 2B17 in high-risk chronic lymphocytic leukemia

Michaela Gruber, Judith Bellemare, Gregor Hoermann, Andreas Gleiss, Edit Porpaczy, Martin Bilban, Trang Le, Sonja Zehetmayer, Christine Mannhalter, Alexander Gaiger, Medhat Shehata, Karin Fleiss, Cathrin Skrabs, Éric Lévesque, Katrina Vanura, Chantal Guillemette, Ulrich Jaeger

Blood (2013) 121 (7): 1175–1183.

https://doi.org/10.1182/blood-2012-08-447359

Published: 2013

Includes: Supplemental data

Journal Articles

Partial Characterization and In Vitro Expansion of Putative CLL Precursor/Stem Cells Which Are Dependent on Bone Marrow Microenvironment for Survival

Medhat Shehata, Rainer Hubmann, Martin Hilgarth, Susanne Schnabl, Dita Demirtas, Elina Ponath, Ekaterina Brynzak, Sabine Strommer, Volker Wachek, Alexander Hauswirth, Berthold Streubel, M.D., Katrina Vanura, Josef Schwarzmeier, Alexander Gaiger, MD, Christoph Zielinski, Peter Valent, Ulrich Jaeger

Blood (2010) 116 (21): 2433.

https://doi.org/10.1182/blood.V116.21.2433.2433

Published: 2010

Journal Articles

Reconstitution of PTEN activity by CK2 inhibitors and interference with the PI3-K/Akt cascade counteract the antiapoptotic effect of human stromal cells in chronic lymphocytic leukemia

Medhat Shehata, Susanne Schnabl, Dita Demirtas, Martin Hilgarth, Rainer Hubmann, Elena Ponath, Sigrun Badrnya, Claudia Lehner, Andrea Hoelbl, Markus Duechler, Alexander Gaiger, Christoph Zielinski, Josef D. Schwarzmeier, Ulrich Jaeger

Blood (2010) 116 (14): 2513–2521.

https://doi.org/10.1182/blood-2009-10-248054

Published: 2010

Includes: Supplemental data

Journal Articles

Lumiliximab Triggers Apoptosis Mechanisms in CLL Cells through the Inhibition of PI3-K/Akt Pathway.

Medhat Shehata, Susanne Schnabl, Elena Ponath, Stefanie Tauber, Dita Demirtas, Martin Hilgarth, Martin Bilban, Sigrun Badrnya, Karin Fleiss, Josef D. Schwarzmeier, Alexander Gaiger, Rainer Hubmann, Christoph C Zielinski, Steve Hughes, Ann Maclaren, Ulrich Jaeger

Blood (2009) 114 (22): 2371.

https://doi.org/10.1182/blood.V114.22.2371.2371

Published: 2009

Journal Articles

Effective Targeting of the PI3-K Pathway in CLL with NVP-BEZ235, a Novel Orally Available Dual PI3K/mTOR Inhibitor

Medhat Shehata, Susanne Schnabl, Dita Demirtas, Stefanie Tauber, Martin Hilgarth, Martin Bilban, Katrina Vanura, Edit Porpaczy, Christa Fonatsch, Stephan Stilgenbauer, MD, PhD, Josef D. Schwarzmeier, Rainer Hubmann, Alexander Gaiger, Christoph Zielinski, MD, Sauveur-Michel Maira, Carlos Garcia-Echeverria, Wolfgang Hackl, Ulrich Jaeger

Blood (2008) 112 (11): 3166.

https://doi.org/10.1182/blood.V112.11.3166.3166

Published: 2008

Journal Articles

Liposome-Encapsulated Doxorubicin Is Highly Active in Patients with B- as Well as T/NK-Cell Lymphomas and Cardiac Comorbidity or Older Age

Cathri n C Skrabs, Alexander Hauswirth, Karin Eigenberger, Christine Einberger, Markus Raderer, Wolfgang R Sperr, Paul Knoebl, Leonhard Muellauer, Martin Uffmann, Karin Dieckmann, Alexander Gaiger, Ulrich Jaeger, MD

Blood (2008) 112 (11): 3587.

https://doi.org/10.1182/blood.V112.11.3587.3587

Published: 2008

Journal Articles

Identification of Genes Associated with Resistance and Response in Vivo to Therapy with Rituximab, Fludarabine and Cyclophosphamide in Patients with Chronic Lymphocytic Leukemia.

Blood (2008) 112 (11): 1622.

https://doi.org/10.1182/blood.V112.11.1622.1622

Published: 2008

Journal Articles

Gene Expression Signature of B-Cell Chronic Lymphocytic Leukemia with Trisomy 12.

Blood (2007) 110 (11): 2079.

https://doi.org/10.1182/blood.V110.11.2079.2079

Published: 2007

Journal Articles

Autoimmune or Chronic Infectious Disease in B-CLL at Diagnosis: Association with Unmutated VH Gene Status and Unfavorable Cytogenetics.

Katrina Vanura, Trang Le, Harald Esterbauer, Florentin Spaeth, Edith Porpaczy, Medhat Shehata, Karin Eigenberger, Alexander Hauswirth, Cathrin Scrabs, Elisabeth Kroemer, Ilse Schwarzinger, Berthold Streubel, Christa Fonatsch, Stephan Stilgenbauer, Alexander Gaiger, Ulrich Jaeger

Blood (2007) 110 (11): 3092.

https://doi.org/10.1182/blood.V110.11.3092.3092

Published: 2007

Journal Articles

Lymphoid Microenvironment Inhibits Apoptosis in B-CLL Cells: Involvement of PI3-K/AKT Pathway and PTEN.

Medhat Shehata, MD, Susanne Schnabl, Dita Demirtas, MD, Josef D. Schwarzmeier, MD, Martin Hilgarth, Markus Duechler, PhD, Alexander Gaiger, MD, Rainer Hubmann, PhD, Ulrich Jaeger, MD

Blood (2006) 108 (11): 1443.

https://doi.org/10.1182/blood.V108.11.1443.1443

Published: 2006

Journal Articles

Predictive Value of Clonal Peripheral Blood γTCR Rearrangement in Patients with Peripheral T-Cell Lymphoma.

Christian Schuetzinger, Harald Esterbauer, MD,PhD, Cathrin Skrabs, MD, Martin Uffmann, MD, Markus Raderer, MD, Alexander Hauswirth, MD, Alexander Gaiger, MD, Christine Mannhalter, PhD, Karin Dieckmann, MD, Oswald Wagner, MD, Ulrich Jaeger, MD

Blood (2006) 108 (11): 2060.

https://doi.org/10.1182/blood.V108.11.2060.2060

Published: 2006

Journal Articles

The Paternally Expressed Gene 10 (PEG10) on Chromosome 7q21 Is Overexpressed and Imprinted in High-Risk B-CLL.

Blood (2005) 106 (11): 1221.

https://doi.org/10.1182/blood.V106.11.1221.1221

Published: 2005

Journal Articles

High Expression of MUM1/IRF4 mRNA Is Associated with a Shorter Overall Survival in Patients with Multiple Myeloma.

Daniel Heintel, MD, Niklas Zojer, MD, Kathrin Strasser-Weippl, MD, Michael Vesely, MD, Heinz Gisslinger, Johannes Drach, Alexander Gaiger, Ulrich Jäger, Heinz Ludwig

Blood (2005) 106 (11): 1550.

https://doi.org/10.1182/blood.V106.11.1550.1550

Published: 2005

Journal Articles

Prognostic Relevance of Lipoprotein Lipase (LPL) Expression in B-CLL.

Daniel Heintel, Dirk Kienle, Bilban Martin, Medhat Shehata, Alexander Kroeber, Dieter Mitteregger, Edith Porpaczy, Birgit Kainz, Michael Auer, Andreas Gleiss, Hartmut Dohner, Alexander Gaiger, Oswald Wagner, Stephan Stilgenbauer, Ulrich Jaeger

Blood (2004) 104 (11): 177.

https://doi.org/10.1182/blood.V104.11.177.177

Published: 2004

Journal Articles

Immunity to WT1 in the animal model and in patients with acute myeloid leukemia

Alexander Gaiger, Valerie Reese, Mary L. Disis, Martin A. Cheever

Blood (2000) 96 (4): 1480–1489.

https://doi.org/10.1182/blood.V96.4.1480

Published: 2000

NARROW

Treatment Guided By Next Generation Functional Drug Screening Provides Clinical Benefit in Advanced Aggressive Hematological Malignancies: Final Evaluation of the Open Label, Single Arm Exalt Trial

Overexpression of uridine diphospho glucuronosyltransferase 2B17 in high-risk chronic lymphocytic leukemia

Partial Characterization and In Vitro Expansion of Putative CLL Precursor/Stem Cells Which Are Dependent on Bone Marrow Microenvironment for Survival

Reconstitution of PTEN activity by CK2 inhibitors and interference with the PI3-K/Akt cascade counteract the antiapoptotic effect of human stromal cells in chronic lymphocytic leukemia

Lumiliximab Triggers Apoptosis Mechanisms in CLL Cells through the Inhibition of PI3-K/Akt Pathway.

Effective Targeting of the PI3-K Pathway in CLL with NVP-BEZ235, a Novel Orally Available Dual PI3K/mTOR Inhibitor

Liposome-Encapsulated Doxorubicin Is Highly Active in Patients with B- as Well as T/NK-Cell Lymphomas and Cardiac Comorbidity or Older Age

Identification of Genes Associated with Resistance and Response in Vivo to Therapy with Rituximab, Fludarabine and Cyclophosphamide in Patients with Chronic Lymphocytic Leukemia.

Gene Expression Signature of B-Cell Chronic Lymphocytic Leukemia with Trisomy 12.

Autoimmune or Chronic Infectious Disease in B-CLL at Diagnosis: Association with Unmutated VH Gene Status and Unfavorable Cytogenetics.

Lymphoid Microenvironment Inhibits Apoptosis in B-CLL Cells: Involvement of PI3-K/AKT Pathway and PTEN.

Predictive Value of Clonal Peripheral Blood γTCR Rearrangement in Patients with Peripheral T-Cell Lymphoma.

The Paternally Expressed Gene 10 (PEG10) on Chromosome 7q21 Is Overexpressed and Imprinted in High-Risk B-CLL.

High Expression of MUM1/IRF4 mRNA Is Associated with a Shorter Overall Survival in Patients with Multiple Myeloma.

Prognostic Relevance of Lipoprotein Lipase (LPL) Expression in B-CLL.

Immunity to WT1 in the animal model and in patients with acute myeloid leukemia

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American Society of Hematology

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ASH Publications

American Society of Hematology

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