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Journal Articles

Cyclin D1 beyond the cell cycle: A new role in t(11;14) multiple myeloma

Blood (2025) 146 (Supplement 1): 3939.

https://doi.org/10.1182/blood-2025-3939

Published: 2025

Journal Articles

Somatic ASXL1 mutations in chronic myelomonocytic leukemia result in loss of imprinting control and overexpression of DLK1 through deregulation of DNA methylation

Pankaj Pradeep, Jenna Fernandez, Abhishek Mangaonkar, Nickolas Steinauer, Moritz Binder, Huihuang Yan, Christy Finke, Zhifu Sun, Terra Lasho, Mrinal Patnaik

Blood (2025) 146 (Supplement 1): 1457.

https://doi.org/10.1182/blood-2025-1457

Published: 2025

Journal Articles

Clone-specific epigenetic regulatory mechanisms in ASXL1-mutant chronic myelomonocytic leukemia

Moritz Binder, Terra Lasho, Jenna Fernandez, Wazim Mohammed Ismail, Amelia Mazzone, Christy Finke, Pankaj Pradeep, Abhishek Mangaonkar, Nickolas Steinauer, Huihuang Yan, Liguo Wang, Alexandre Gaspar-Maia, Mrinal Patnaik

Blood (2025) 146 (Supplement 1): 234.

https://doi.org/10.1182/blood-2025-234

Published: 2025

Journal Articles

Cyclin D1 Induces Global Epigenetic and Transcriptional Changes in Multiple Myeloma with t(11;14)(q13;q32)

Huihuang Yan, Suganti Shivaram, Hongwei Tang, Hans Anderson, Shulan Tian, Michael D Howe, Abiola Bolarinwa, Cinthya Zepeda Mendoza, Stacey Lehman, Leif Bergsagel, Esteban Braggio, Rafael Fonseca, Shaji Kumar, Francesco Maura, Linda B. Baughn

Blood (2024) 144 (Supplement 1): 6822.

https://doi.org/10.1182/blood-2024-208503

Published: 2024

Journal Articles

Targeting Aberrant DLK1 Re-Expression in ASXL1 -Mutant Chronic Myelomonocytic Leukemia with BRD4 / p300-Directed Epigenetic Small Molecule Therapy

Terra L. Lasho, Jenna A. Fernandez, Jeong-Heon Lee, Linh D. Pham, Huihuang Yan, Christy Finke, Abhishek A. Mangaonkar, Aref Al-Kali, Naseema Gangat, Joseph Collard, Claes Wahlestedt, Mrinal M. Patnaik, Moritz Binder

Blood (2024) 144 (Supplement 1): 3197.

https://doi.org/10.1182/blood-2024-204070

Published: 2024

Journal Articles

The Role of NOXA in Venetoclax Treatment Response in Multiple Myeloma

Blood (2024) 144 (Supplement 1): 4635.

https://doi.org/10.1182/blood-2024-205385

Published: 2024

Journal Articles

Serum Immunoglobulins Are an Independent Prognostic Marker of Time to First Therapy in Newly Diagnosed Chronic Lymphocytic Leukemia (CLL) and Monoclonal B-Cell Lymphocytosis (MBL)

Blood (2024) 144 (Supplement 1): 4616.

https://doi.org/10.1182/blood-2024-194925

Published: 2024

Journal Articles

Prediction of outcomes for high-count monoclonal B lymphocytosis using an epigenetic and immunogenetic signature

Salma B. Abdelbaky, Brian Giacopelli, Kari G. Rabe, Kyoko Yamaguchi, Yue-Zhong Wu, Huihuang Yan, Tait D. Shanafelt, Sameer A. Parikh, Wei Ding, Paul J. Hampel, Sochilt Brown, James R. Cerhan, Celine M. Vachon, Neil E. Kay, Curtis A. Hanson, Alexander S. Parker, Esteban Braggio, Susan L. Slager, Christopher C. Oakes

Blood (2024) 143 (17): 1752–1757.

https://doi.org/10.1182/blood.2023022180

Published: 2024

Includes: Supplemental data

Journal Articles

PD-1 Expression in Lymphoma Cells Mediates Cellular Proliferation By Engaging Phosphatase SHP-1/SHP-2

Blood (2023) 142 (Supplement 1): 3261.

https://doi.org/10.1182/blood-2023-177755

Published: 2023

Journal Articles

Variation in the Immune Tumor Microenvironment in Relation to Self-Reported Race in Individuals with Multiple Myeloma

Neeraj Sharma, Hongwei Tang, Huihuang Yan, Shulan Tian, Suganti Shivaram, Taxiarchis Kourelis, Shaji K Kumar, Linda B. Baughn

Blood (2022) 140 (Supplement 1): 4209–4210.

https://doi.org/10.1182/blood-2022-166744

Published: 2022

Journal Articles

TP53 Aberrations and Outcomes in MBL and Untreated CLL

Rosalie Griffin Waller, Julia E. Wiedmeier, Nicholas J. Boddicker, Geffen Kleinstern, Cecilia Bonolo De Campos, Daniel L. Van Dyke, Huihuang Yan, Celine M. Vachon, Daniel R. O'Brien, Cristine Allmer, Kari G. Rabe, James R. Cerhan, Timothy G. Call, Sameer A. Parikh, Neil E. Kay, Esteban Braggio, Susan L. Slager

Blood (2021) 138 (Supplement 1): 2618.

https://doi.org/10.1182/blood-2021-153602

Published: 2021

Journal Articles

B Cell Receptor Signaling Drives APOBEC3 Expression Via Direct Enhancer Regulation in Chronic Lymphocytic Leukemia B Cells

Zhiquan Wang, Huihuang Yan, Justin C. Boysen, Charla R. Secreto, Esteban Braggio, Susan L. Slager, Sameer A. Parikh, Neil E. Kay

Blood (2021) 138 (Supplement 1): 3313.

https://doi.org/10.1182/blood-2021-153214

Published: 2021

Journal Articles

Utilization of a Targeted Next Generation Sequencing Assay to Identify Copy Number Alterations in Chronic Lymphocytic Leukemia and Monoclonal B-Cell Lymphocytosis

Julia E. Wiedmeier, Chantal McCabe, Daniel R. O'Brien, Nicholas J. Boddicker, Rosalie Griffin Waller, Cecilia Bonolo De Campos, James R. Cerhan, Sameer A. Parikh, Neil E. Kay, Huihuang Yan, Daniel L. Van Dyke, Susan L. Slager, Esteban Braggio

Blood (2021) 138 (Supplement 1): 4677.

https://doi.org/10.1182/blood-2021-153001

Published: 2021

Journal Articles

Identification of a Novel Role for PD-1 Signaling in Promotion Tumor Proliferation in B-Cell Lymphoma

Blood (2020) 136 (Supplement 1): 10–12.

https://doi.org/10.1182/blood-2020-136550

Published: 2020

Journal Articles

Genomic Profiling Reveals Molecular Heterogeneity in Patients with Richter's Syndrome (RS) and Progressive Chronic Lymphocytic Leukemia (CLL)

Shulan Tian, MS, PhD, Hanyin Wang, MD, Timothy G. Call, MD, Eric W. Klee, PhD, Minetta C. Liu, MD, Erik Jessen, PhD, Sameer A. Parikh, MD, Yucai Wang, MDPhD, Saad S. Kenderian, MB, ChB, Jose F. Leis, MD PhD, Min Shi, MDPhD, Eli Muchtar, MD, Daniel L. Van Dyke, PhD, Amber B. Koehler, PA-C, MS, Neil E. Kay, MD, Susan L. Slager, PhD, Esteban Braggio, PhD, Huihuang Yan, PhD, Wei Ding, MD PhD

Blood (2020) 136 (Supplement 1): 16–17.

https://doi.org/10.1182/blood-2020-138397

Published: 2020

Journal Articles

Distinct Gene Expression Signatures in Patients with Richter's Syndrome and Chronic Lymphocytic Leukemia with Prior Exposure to Ibrutinib

Hanyin Wang, MD, Shulan Tian, MS, PhD, Qing Zhao, Wendy Blumenschein, Jennifer H. Yearley, PhD, Charla R. Secreto, Sutapa Sinha, PhD, Timothy G. Call, MD, Yucai Wang, MDPhD, Sameer A. Parikh, MD, Saad S. Kenderian, MB, ChB, Rong He, MD, Jose F. Leis, MD PhD, Min Shi, MDPhD, Neil E. Kay, MD, Susan L. Slager, PhD, Esteban Braggio, PhD, Huihuang Yan, PhD, Wei Ding, MD PhD

Blood (2020) 136 (Supplement 1): 30–31.

https://doi.org/10.1182/blood-2020-136172

Published: 2020

Journal Articles

Targeting Aberrant Chromatin in Chronic Lymphocytic Leukemia

Zhiquan Wang, PhD, Justin C. Boysen, Huihuang Yan, PhD, Charla R. Secreto, Sameer A. Parikh, MD, Saad S. Kenderian, MB, ChB, Wei Ding, MD PhD, Esteban Braggio, PhD, Susan L. Slager, PhD, Neil E. Kay, MD

Blood (2020) 136 (Supplement 1): 1.

https://doi.org/10.1182/blood-2020-140309

Published: 2020

Journal Articles

Tumor Mutational Load and Germline Polygenic Risk Score Predicts Time-to-First Treatment in Chronic Lymphocytic Leukemia (CLL) and High-Count Monoclonal B Cell Lymphocytosis (MBL)

Geffen Kleinstern, PhD, Daniel R O'Brien, Brian Kabat, B.S., Kari G Rabe, Aaron D. Norman, Huihuang Yan, PhD, Celine M. Vachon, PhD, Shulan Tian, MS, PhD, Timothy G. Call, MD, Sameer A. Parikh, MD, Jose F. Leis, MD PhD, Wei Ding, MD PhD, James R. Cerhan, MD PhD, Neil E. Kay, MD, Esteban Braggio, PhD, Susan L. Slager, PhD

Blood (2019) 134 (Supplement_1): 852.

https://doi.org/10.1182/blood-2019-124346

Published: 2019

Journal Articles

Recurrent MSC E116K mutations in ALK-negative anaplastic large cell lymphoma

Blood (2019) 133 (26): 2776–2789.

https://doi.org/10.1182/blood.2019000626

Published: 2019

Includes: Supplemental data

Journal Articles

PD-1 Overexpression in Richter's Transformation (RT) and Aggressive Chronic Lymphocytic Leukemia (CLL) after Progression on Ibrutinib Increases Bcl-2 Expression Via Akt/mTOR Pathway

Sutapa Sinha, PhD, Tammy Price-Troska, BS, Shulan Tian, MS, PhD, Charla R Secreto, Xiaosheng Wu, MD, Timothy G. Call, MD, Rong He, MD, Sameer A. Parikh, MD, Saad S. Kenderian, MD, Jose F. Leis, MD PhD, Huihuang Yan, PhD, Karen L Rech, MD, Minetta C Liu, MD, Stephen M. Ansell, MD PhD, Neil E. Kay, MD, Wei Ding, MD PhD

Blood (2018) 132 (Supplement 1): 586.

https://doi.org/10.1182/blood-2018-99-112575

Published: 2018

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Cyclin D1 beyond the cell cycle: A new role in t(11;14) multiple myeloma

Somatic ASXL1 mutations in chronic myelomonocytic leukemia result in loss of imprinting control and overexpression of DLK1 through deregulation of DNA methylation

Clone-specific epigenetic regulatory mechanisms in ASXL1-mutant chronic myelomonocytic leukemia

Cyclin D1 Induces Global Epigenetic and Transcriptional Changes in Multiple Myeloma with t(11;14)(q13;q32)

Targeting Aberrant DLK1 Re-Expression in ASXL1 -Mutant Chronic Myelomonocytic Leukemia with BRD4 / p300-Directed Epigenetic Small Molecule Therapy

The Role of NOXA in Venetoclax Treatment Response in Multiple Myeloma

Serum Immunoglobulins Are an Independent Prognostic Marker of Time to First Therapy in Newly Diagnosed Chronic Lymphocytic Leukemia (CLL) and Monoclonal B-Cell Lymphocytosis (MBL)

Prediction of outcomes for high-count monoclonal B lymphocytosis using an epigenetic and immunogenetic signature

PD-1 Expression in Lymphoma Cells Mediates Cellular Proliferation By Engaging Phosphatase SHP-1/SHP-2

Variation in the Immune Tumor Microenvironment in Relation to Self-Reported Race in Individuals with Multiple Myeloma

TP53 Aberrations and Outcomes in MBL and Untreated CLL

B Cell Receptor Signaling Drives APOBEC3 Expression Via Direct Enhancer Regulation in Chronic Lymphocytic Leukemia B Cells

Utilization of a Targeted Next Generation Sequencing Assay to Identify Copy Number Alterations in Chronic Lymphocytic Leukemia and Monoclonal B-Cell Lymphocytosis

Identification of a Novel Role for PD-1 Signaling in Promotion Tumor Proliferation in B-Cell Lymphoma

Genomic Profiling Reveals Molecular Heterogeneity in Patients with Richter's Syndrome (RS) and Progressive Chronic Lymphocytic Leukemia (CLL)

Distinct Gene Expression Signatures in Patients with Richter's Syndrome and Chronic Lymphocytic Leukemia with Prior Exposure to Ibrutinib

Targeting Aberrant Chromatin in Chronic Lymphocytic Leukemia

Tumor Mutational Load and Germline Polygenic Risk Score Predicts Time-to-First Treatment in Chronic Lymphocytic Leukemia (CLL) and High-Count Monoclonal B Cell Lymphocytosis (MBL)

Recurrent MSC E116K mutations in ALK-negative anaplastic large cell lymphoma

PD-1 Overexpression in Richter's Transformation (RT) and Aggressive Chronic Lymphocytic Leukemia (CLL) after Progression on Ibrutinib Increases Bcl-2 Expression Via Akt/mTOR Pathway

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