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Vikas A Gupta
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Journal Articles

Machine Learning Models Predict Molecular Genetic Subtypes of Multiple Myeloma from Whole-Slide Bone Marrow Aspirate Smears

Joshua E Lewis, Conrad W Shebelut, Michel Attieh, Michael C Horwath, Anurag Khanna, Omar M Al-Rusan, Tanya Ponnatt, Geoffrey H Smith, David A Gutman, Vikas A Gupta, Ahmed Aljudi, Lee A.D. Cooper, David L Jaye
Journal: Blood
Blood (2023) 142 (Supplement 1): 7158.
https://doi.org/10.1182/blood-2023-190686
Published: 2023
Journal Articles

Efficacy of D-RVD Vs RVD Among t(11;14) Patients with Newly Diagnosed Myeloma

Jonathan L. Kaufman, Nisha S. Joseph, Vikas A. Gupta, Sara Dicamillo, Danielle Roberts, Craig C. Hofmeister, Madhav V. Dhodapkar, Ajay K. Nooka, Sagar Lonial, Lawrence H. Boise
Journal: Blood
Blood (2023) 142 (Supplement 1): 4699.
https://doi.org/10.1182/blood-2023-181783
Published: 2023
Journal Articles

A Randomized Phase II Study of Daratumumab, Ixazomib, and Dexamethasone (DId, Arm A) Vs Daratumumab, Bortezomib and Dexamethasone (DVd) Followed By Daratumumab, Did (Arm B) in Newly Diagnosed Multiple Myeloma (DeRIVE) Study

Ajay K. Nooka, Nisha S. Joseph, Vikas A. Gupta, Craig C. Hofmeister, Madhav V. Dhodapkar, Bryan J Burton, Hafsa M Ahmed, Darrian Linton, Annelore Cortoos, Thomas S. Lin, Richard Labotka, Stephen J. Noga, Jonathan L. Kaufman, Sagar Lonial
Journal: Blood
Blood (2023) 142 (Supplement 1): 4764.
https://doi.org/10.1182/blood-2023-190871
Published: 2023
Journal Articles

Prophylactic Tocilizumab to Prevent Cytokine Release Syndrome (CRS) with Teclistamab Administration

Ellen Marin, Sara Scott, Kathryn Maples, Nisha S. Joseph, Craig C. Hofmeister, Vikas A. Gupta, Madhav V. Dhodapkar, Jonathan L. Kaufman, Sagar Lonial, Ajay K. Nooka
Journal: Blood
Blood (2023) 142 (Supplement 1): 2008.
https://doi.org/10.1182/blood-2023-189878
Published: 2023
Journal Articles

Comparison of Response and Survival Outcomes in Standard- and High-Risk Newly Diagnosed Transplant-Eligible Multiple Myeloma (NDMM) Patients Treated with Lenalidomide, Bortezomib and Dexamethasone (RVD) Versus Daratumumab, Lenalidomide, Bortezomib and Dexamethasone (D-RVD)

Nisha S. Joseph, Jonathan L. Kaufman, Sara Dicamillo, Danielle Roberts, Vikas A. Gupta, Craig C. Hofmeister, Madhav V. Dhodapkar, Lawrence H. Boise, Sagar Lonial, Ajay K. Nooka
Journal: Blood
Blood (2023) 142 (Supplement 1): 647.
https://doi.org/10.1182/blood-2023-187339
Published: 2023
Journal Articles

Tumor-Immune Architecture and the Regulation of Antigen-Specific T-Cell Infiltration in Multiple Myeloma and Premalignant Plasma Cell Disorders

Hope Robinson, Nancy Villa, David L Jaye, Ajay K. Nooka, Alyssa Duffy, Samuel McCachren, Julia Manalo, Jeffrey M. Switchenko, Ava Horvat, Vaunita C Parihar, Jingjing Gong, Yan Liang, Geoffrey Smith, Vikas A Gupta, Lawrence H. Boise, Jonathan L. Kaufman, Craig C Hofmeister, Nisha Joseph, Sagar Lonial, Kavita Dhodapkar, Madhav Dhodapkar
Journal: Blood
Blood (2022) 140 (Supplement 1): 244–245.
https://doi.org/10.1182/blood-2022-169558
Published: 2022
Journal Articles

It takes T to tango: immunotherapy in MM

Clinical Trials & Observations
Vikas A. Gupta, Madhav V. Dhodapkar
Journal: Blood
Blood (2022) 139 (9): 1259–1260.
https://doi.org/10.1182/blood.2021013816
Published: 2022
Journal Articles

PI3Kδ/γ inhibition promotes human CART cell epigenetic and metabolic reprogramming to enhance antitumor cytotoxicity

Christopher Ronald Funk, Shuhua Wang, Kevin Z. Chen, Alexandra Waller, Aditi Sharma, Claudia L. Edgar, Vikas A. Gupta, Shanmuganathan Chandrakasan, Jaquelyn T. Zoine, Andrew Fedanov, Sunil S. Raikar, Jean L. Koff, Christopher R. Flowers, Silvia Coma, Jonathan A. Pachter, Sruthi Ravindranathan, H. Trent Spencer, Mala Shanmugam, Edmund K. Waller
Journal: Blood
Blood (2022) 139 (4): 523–537.
https://doi.org/10.1182/blood.2021011597
Published: 2022
Includes: Supplemental data
Journal Articles

Mitochondrial Electron Transport Chain Inhibition Promotes Resistance to Proteasome Inhibitors in Multiple Myeloma

Aditi Sharma, Abhinav Achreja, Remya Nair, Pulkit Gupta, Claudia L Edgar, Olamide Animasahun, Anjali Mittal, Bhakti Dwivedi, Manoj Bhasin, Vikas A Gupta, Benjamin G Barwick, Shannon M Matulis, Sagar Lonial, Lawrence H. Boise, David L Jaye, Arun P Wiita, Ajay K. Nooka, Deepak Nagrath, Mala Shanmugam
Journal: Blood
Blood (2021) 138 (Supplement 1): 1611.
https://doi.org/10.1182/blood-2021-153744
Published: 2021
Journal Articles

BRAF Mutations and Inflammatory Gene Expression in Myeloma Cells from Patients with Renal Dysfunction

Theodora Alese, Benjamin G Barwick, Vikas A. Gupta, Nisha Joseph, Craig C. Hofmeister, Mala Shanmugam, Jonathan L. Kaufman, Madhav V Dhodapkar, Sagar Lonial, Ajay K. Nooka, Lawrence H. Boise
Journal: Blood
Blood (2021) 138 (Supplement 1): 1624.
https://doi.org/10.1182/blood-2021-154092
Published: 2021
Journal Articles

Daratumumab with Pomalidomide and Dexamethasone at First Relapse in Relapsed and/or Refractory Multiple Myeloma (RRMM) Patients

Nisha Joseph, Kathryn T. Maples, Kevin Hall, Vikas A Gupta, Larry H. Boise, Leonard T. Heffner, Madhav V Dhodapkar, Craig C. Hofmeister, Jonathan L. Kaufman, Sagar Lonial, Ajay K. Nooka
Journal: Blood
Blood (2021) 138 (Supplement 1): 1616.
https://doi.org/10.1182/blood-2021-151161
Published: 2021
Journal Articles

Venetoclax sensitivity in multiple myeloma is associated with B-cell gene expression

Vikas A. Gupta, Benjamin G. Barwick, Shannon M. Matulis, Ryosuke Shirasaki, David L. Jaye, Jonathan J. Keats, Benjamin Oberlton, Nisha S. Joseph, Craig C. Hofmeister, Leonard T. Heffner, Madhav V. Dhodapkar, Ajay K. Nooka, Sagar Lonial, Constantine S. Mitsiades, Jonathan L. Kaufman, Lawrence H. Boise
Journal: Blood
Blood (2021) 137 (26): 3604–3615.
https://doi.org/10.1182/blood.2020007899
Published: 2021
Includes: Supplemental data
Journal Articles

Chromatin Accessibility Identifies Regulatory Elements Predictive of Oncogene Expression in Multiple Myeloma

Benjamin G Barwick, PhD, Vikas A. Gupta, MD PhD, Shannon M Matulis, PhD, Jonathan C Patton, B.S., Doris R Powell, MA, Yanyan Gu, MD PhD, David L. Jaye, MD, Karen N Conneely, PhD, Yin C Lin, PhD, Craig C Hofmeister, MDMPH, Ajay Nooka, MDMPH, Jonathan J Keats, PhD, Sagar Lonial, MD FACP, Paula M Vertino, PhD, Larry H. Boise, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 31–32.
https://doi.org/10.1182/blood-2020-140717
Published: 2020
Journal Articles

Evaluating Outcomes for Autologous Hematopoietic Cell Transplantation for Diffuse Large B-Cell Lymphoma in the CAR-T Era

Pranav R Santapuram, Manali Rupji, MS, Michael Graiser, PhD, Edmund K. Waller, PhDMD, Kristie A. Blum, MD, Pamela B. Allen, MD MSc, Jean L. Koff, MD, Leonard Heffner, MD, Mary Jo Lechowicz, MD, Sagar Lonial, MD FACP, Jonathan L. Kaufman, MD, Craig C Hofmeister, MDMPH, Madhav V. Dhodapkar, MD, Ajay Nooka, MDMPH, William Blum, MD, Rebecca B. Klisovic, MD, Nisha Joseph, MD, Vikas A. Gupta, MD PhD, Amelia Langston, MD, Jonathon B. Cohen, MDMS
Journal: Blood
Blood (2020) 136 (Supplement 1): 20–21.
https://doi.org/10.1182/blood-2020-142110
Published: 2020
Journal Articles

Statins Enhance Killing of Multiple Myeloma Cells By the BCL-2 Inhibitor Venetoclax and the MCL-1 Inhibitor S63845

David Fruman, PhD, Dennis Juarez, B.S., Grace Diep, Undergraduate, Falisha Nguyen, Undergraduate, Vikas A. Gupta, MD PhD, Lawrence H. Boise, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4413.
https://doi.org/10.1182/blood-2019-131218
Published: 2019
Journal Articles

The Role of Proteasome Activator PA28α in Multiple Myeloma

Yanyan Gu, MD PhD, Benjamin G Barwick, PhD, Mala Shanmugam, PhD, Craig C Hofmeister, MDMPH, Jonathan L. Kaufman, MD, Ajay K Nooka, MDMPH, Vikas A. Gupta, MD PhD, Madhav V Dhodapkar, MBBS, Lawrence H. Boise, PhD, Sagar Lonial
Journal: Blood
Blood (2019) 134 (Supplement_1): 5499.
https://doi.org/10.1182/blood-2019-128216
Published: 2019
Journal Articles

Immunoglobulin Lambda Translocations Identify Poor Outcome and IMiD Resistance in Multiple Myeloma and Co-Occur with Hyperdiploidy

Benjamin G Barwick, PhD, Paola Neri, MD, Nizar Bahlis, MD, Ajay K Nooka, MDMPH, Jonathan L Kaufman, MD, Vikas A. Gupta, MD PhD, Daniel Auclair, PhD, Jonathan J Keats, PhD, Sagar Lonial, MD, Paula M Vertino, PhD, Lawrence H. Boise, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 405.
https://doi.org/10.1182/blood-2018-99-113585
Published: 2018
Journal Articles

Efficacy of Induction Thearapy with Lenalidomide, Bortezomib, and Dexamethasone (RVD) in 1000 Newly Diagnosed Multiple Myeloma (MM) Patients

Nisha Joseph, MD, Vikas A. Gupta, MD PhD, Craig C Hofmeister, MD MPH, Charise Gleason, ANP, Leonard Heffner, MD, Lawrence H. Boise, PhD, Jonathan L Kaufman, MD, Madhav V Dhodapkar, MD, Sagar Lonial, MD, Ajay K Nooka, MD MPH
Journal: Blood
Blood (2018) 132 (Supplement 1): 3294.
https://doi.org/10.1182/blood-2018-99-119895
Published: 2018
Journal Articles

Preclinical Activity of Novel MCL1 Inhibitor AZD5991 in Multiple Myeloma

Shannon M Matulis, PhD, Vikas A. Gupta, MD PhD, Izabelle Brown, Jonathan J Keats, PhD, Paul Secrist, PhD, Justin Cidado, PhD, Adriana E. Tron, PhD, Paola Neri, MD, Nizar Bahlis, MD, Jonathan L Kaufman, MD, Leonard Heffner, MD, Sagar Lonial, MD, Ajay K Nooka, MDMPH, Lawrence H. Boise, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 952.
https://doi.org/10.1182/blood-2018-99-113504
Published: 2018
Journal Articles

Outcomes and Clinical Features of Patients with 1q+ Multiple Myeloma Treated with Lenalidomide, Bortezomib, and Dexamethasone

Timothy M. Schmidt, MD, Nisha Joseph, MD, Levani Odikadze, MD MPH, Leonard Heffner, MD, Craig C Hofmeister, MD MPH, Madhav V Dhodapkar, MD, Vikas A. Gupta, MD PhD, Lawrence H. Boise, PhD, David L. Jaye, MD, Sagar Lonial, MD, Ajay K Nooka, MD MPH, Jonathan L Kaufman, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3241.
https://doi.org/10.1182/blood-2018-99-112216
Published: 2018