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Linda B. Baughn
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Journal Articles

Cyclin D1 Induces Global Epigenetic and Transcriptional Changes in Multiple Myeloma with t(11;14)(q13;q32)

Huihuang Yan, Suganti Shivaram, Hongwei Tang, Hans Anderson, Shulan Tian, Michael D Howe, Abiola Bolarinwa, Cinthya Zepeda Mendoza, Stacey Lehman, Leif Bergsagel, Esteban Braggio, Rafael Fonseca, Shaji Kumar, Francesco Maura, Linda B. Baughn
Journal: Blood
Blood (2024) 144 (Supplement 1): 6822.
https://doi.org/10.1182/blood-2024-208503
Published: 2024
Journal Articles

Genomic Determinants of Clinical Outcomes in Multiple Myeloma with t(11;14)(CCND1;IGH) Treated with Venetoclax

Marcella Kaddoura, J Erin Wiedmeier-Nutor, Vikas A. Gupta, Bachisio Ziccheddu, Suganti Shivaram, Hongwei Tang, Rodrigo Fonseca, Michael Durante, Shannon M Matulis, Tomas Jelinek, Ola Landgren, Constantine S Mitsiades, P. Leif Bergsagel, Esteban Braggio, Lawrence H. Boise, Rafael Fonseca, Shaji Kumar, Francesco Maura, Linda B. Baughn
Journal: Blood
Blood (2024) 144 (Supplement 1): 249.
https://doi.org/10.1182/blood-2024-204071
Published: 2024
Journal Articles

The Role of NOXA in Venetoclax Treatment Response in Multiple Myeloma

Suganti Shivaram, Huihuang Yan, Hongwei Tang, Hans M. Anderson, Marcella Kaddoura, J Erin Wiedmeier-Nutor, Shulan Tian, Michael D Howe, Abiola Bolarinwa, Cinthya Zepeda Mendoza, Vikas A Gupta, Stacey Lehman, Constantine S Mitsiades, P. Leif Bergsagel, Esteban Braggio, Lawrence H. Boise, Rafael Fonseca, Francesco Maura, Shaji Kumar, Linda B. Baughn
Journal: Blood
Blood (2024) 144 (Supplement 1): 4635.
https://doi.org/10.1182/blood-2024-205385
Published: 2024
Journal Articles

Convergent Evolution Towards CD38 Biallelic Loss Is a Recurrent Mechanism of Resistance to Anti-CD38 Antibodies in Multiple Myeloma

Benjamin Diamond, Linda B. Baughn, Mansour Poorebrahim, Alexandra Maria Poos, Holly Lee, Marcella Kaddoura, J Erin Wiedmeier-Nutor, Michael Durante, Gregory Otteson, Dragan Jevremovic, Hongwei Tang, Stefan Frohling, Marios Papadimitriou, Bachisio Ziccheddu, Tomas Jelinek, Ola Landgren, Paola Neri, P. Leif Bergsagel, Esteban Braggio, Shaji Kumar, Marc S. Raab, Rafael Fonseca, Nizar J. Bahlis, Niels Weinhold, Francesco Maura
Journal: Blood
Blood (2024) 144 (Supplement 1): 592.
https://doi.org/10.1182/blood-2024-201056
Published: 2024
Journal Articles

Preclinical Development of a Novel Pan-RAS Inhibitor Against Relapsed/Refractory Multiple Myeloma

Jeremiah C. Pfitzer, Razan Waliagha, Linda B. Baughn, Adam B. Keeton, Xi Chen, Yulia Maxuitenko, Shaji Kumar, Brian Van Ness, Gary Piazza, Amit K Mitra
Journal: Blood
Blood (2024) 144 (Supplement 1): 3263.
https://doi.org/10.1182/blood-2024-207683
Published: 2024
Journal Articles

Real World Outcomes with Venetoclax (Ven)-Based Therapies in Patients with Heavily Pretreated Relapsed/Refractory Multiple Myeloma (RRMM): A Mayo Clinic Comprehensive Cancer Center (MCCC) Experience

Ricardo D. Parrondo, Saurav Das, Hanna Sledge, Abiola Bolarinwa, Jamie Elliott, Andre Fernandez, David O. Hodge, Leif Bergsagel, Rafael Fonseca, Prashant Kapoor, Francis Buadi, Morie A. Gertz, Angela Dispenzieri, Vivek Roy, Taimur Sher, Moritz Binder, Nadine Abdallah, Saurabh Chhabra, S. Vincent Rajkumar, Wilson I. Gonsalves, Joselle Cook, David Dingli, Saurabh Zanwar, Yi Lin, Eli Muchtar, Caitlin Wilson, Udit Yadav, Rahma M Warsame, J E Wiedmeier-Nutor, Taxiarchis Kourelis, Nelson Leung, Madhu Nagaraj, Mustaqeem A. Siddiqui, Linda B. Baughn, Shaji Kumar, Asher A. Chanan-Khan, Sikander Ailawadhi
Journal: Blood
Blood (2024) 144 (Supplement 1): 1981.
https://doi.org/10.1182/blood-2024-208294
Published: 2024
Journal Articles

Outcomes of Venetoclax-Based Treatment Combinations in Relapsed/Refractory Multiple Myeloma: Real-World Practice Patterns and Impact of Cytogenetics on Outcomes

Abiola Bolarinwa, Madhu Nagaraj, Saurabh Zanwar, Nadine Abdallah, P. Leif Bergsagel, Moritz Binder, Francis Buadi, Saurabh Chhabra, Joselle Cook, David Dingli, Angela Dispenzieri, Morie A. Gertz, Wilson I. Gonsalves, Suzanne R Hayman, Prashant Kapoor, Taxiarchis Kourelis, Nelson Leung, Yi Lin, Eli Muchtar, Ricardo D. Parrondo, Vivek Roy, Taimur Sher, Mustaqeem A. Siddiqui, Rahma M Warsame, Amie Fonder, Miriam Hobbs, Yi Lisa Hwa, Michelle G. Rogers, Udit Yadav, J E Wiedmeier-Nutor, Dragan Jevremovic, Linda B. Baughn, Vincent Rajkumar, Rafael Fonseca, Sikander Ailawadhi, Shaji Kumar
Journal: Blood
Blood (2024) 144 (Supplement 1): 4728.
https://doi.org/10.1182/blood-2024-208736
Published: 2024
Journal Articles

Impact of cytogenetic abnormalities on the risk of disease progression in solitary bone plasmacytomas

Clinical Trials & Observations
Udit Yadav, Shaji K. Kumar, Linda B. Baughn, Angela Dispenzieri, Patricia Greipp, Rhett Ketterling, Dragan Jevremovic, Francis K. Buadi, David Dingli, Martha Q. Lacy, Rafael Fonseca, P. Leif Bergsagel, Sikander Ailawadhi, Vivek Roy, Ricardo Parrondo, Taimur Sher, Suzanne R. Hayman, Prashant Kapoor, Nelson Leung, Joselle Cook, Moritz Binder, Eli Muchtar, Rahma Warsame, Taxiarchis V. Kourelis, Ronald S. Go, Yi Lin, Abhishek Seth, Scott C. Lester, William G. Breen, Robert A. Kyle, Morie A. Gertz, S. Vincent Rajkumar, Wilson I. Gonsalves
Journal: Blood
Blood (2023) 142 (22): 1871–1878.
https://doi.org/10.1182/blood.2023021187
Published: 2023
Includes: Supplemental data
Journal Articles

A Single Next Generation Sequencing Assay for Detection of Driver Mutations, Translocations and Copy Number Alterations in Patients with Multiple Myeloma

Cecilia Bonolo De Campos, James B Smadbeck, Mariano Arribas, Neeraj Sharma, Gregory J Ahmann, Shaji K Kumar, A. Keith Stewart, Rafael Fonseca, P. Leif Bergsagel, Yan Asmann, Linda B. Baughn, Esteban Braggio
Journal: Blood
Blood (2022) 140 (Supplement 1): 7180–7181.
https://doi.org/10.1182/blood-2022-170749
Published: 2022
Journal Articles

Variation in the Immune Tumor Microenvironment in Relation to Self-Reported Race in Individuals with Multiple Myeloma

Neeraj Sharma, Hongwei Tang, Huihuang Yan, Shulan Tian, Suganti Shivaram, Taxiarchis Kourelis, Shaji K Kumar, Linda B. Baughn
Journal: Blood
Blood (2022) 140 (Supplement 1): 4209–4210.
https://doi.org/10.1182/blood-2022-166744
Published: 2022
Journal Articles

Validation of a Novel Rac1 Inhibitor As Potent Secdrug Against Activating Ras Mutant and Drug-Resistant Multiple Myeloma

Salsabil Ahmed, Suman Mazumder, Lisa Wiesen, Neeraj Sharma, Ujjal Kumar Mukherjee, Shaji K Kumar, Linda B. Baughn, Brian G. Van Ness, Amit Kumar Mitra
Journal: Blood
Blood (2022) 140 (Supplement 1): 4249–4250.
https://doi.org/10.1182/blood-2022-164501
Published: 2022
Journal Articles

Current Testing Practices for t(11;14) Rearrangements in Patients with Newly Diagnosed Multiple Myeloma in the United States

Linda B. Baughn, Elizabeth S. Mearns, Michael Nixon, Vivek S. Chopra, Allicia Girvan, R. Frank Cornell, Jayeta Saxena, Bethany M. Slifko, Jordan Clark, Shaji K Kumar
Journal: Blood
Blood (2022) 140 (Supplement 1): 10114–10115.
https://doi.org/10.1182/blood-2022-158076
Published: 2022
Journal Articles

Characterization of Genetic Findings Underlying Aggressive B-Cell Lymphomas with Atypical Results on MYC Break-Apart Fluorescence in Situ Hybridization (FISH) Analysis

Marie-France Gagnon, Alan R Penheiter, Sarah H Johnson, James B Smadbeck, Dorsay Sadeghian, Faye R Harris, Giannoula Karagouga, Alexa McCune, Nicole L Hoppman, Xinjie Xu, Rhett P. Ketterling, Patricia Greipp, Jess F Peterson, George Vasmatzis, Rebecca L. King, Linda B. Baughn
Journal: Blood
Blood (2022) 140 (Supplement 1): 9272–9273.
https://doi.org/10.1182/blood-2022-158832
Published: 2022
Journal Articles

Guiding the global evolution of cytogenetic testing for hematologic malignancies

Yassmine M. N. Akkari, Linda B. Baughn, Adrian M. Dubuc, Adam C. Smith, Mar Mallo, Paola Dal Cin, Maria Diez Campelo, Marta S. Gallego, Isabel Granada Font, Detlef T. Haase, Brigitte Schlegelberger, Irma Slavutsky, Cristina Mecucci, Ross L. Levine, Robert P. Hasserjian, Francesc Solé, Brynn Levy, Xinjie Xu
Journal: Blood
Blood (2022) 139 (15): 2273–2284.
https://doi.org/10.1182/blood.2021014309
Published: 2022
Journal Articles

False-Negative Centromere 15 Probe Results in Association with African Ancestry in Plasma Cell Dyscrasias

Alaa Koleilat, Hongwei Tang, James B Smadbeck, Neeraj Sharma, Kathryn E. Pearce, Eran Elhaik, Michael L. Baird, Yan Asmann, Patricia Greipp, Jess F Peterson, Rhett P. Ketterling, S. Vincent Rajkumar, Shaji Kumar, Linda B Baughn
Journal: Blood
Blood (2021) 138 (Supplement 1): 4101.
https://doi.org/10.1182/blood-2021-152654
Published: 2021
Journal Articles

Assessing the Prognostic Utility of the Mayo 2018 and IMWG 2020 Smoldering Multiple Myeloma Risk Stratification Scores When Applied Post Diagnosis

Alissa Visram, S. Vincent Rajkumar, Prashant Kapoor, Angela Dispenzieri, Martha Q. Lacy, Morie A. Gertz, Francis K. Buadi, Suzanne R. Hayman, David Dingli, Taxiarchis Kourelis, Wilson I Gonsalves, Rahma M Warsame, Eli Muchtar, Nelson Leung, Linda B Baughn, Robert A. Kyle, Shaji Kumar
Journal: Blood
Blood (2021) 138 (Supplement 1): 543.
https://doi.org/10.1182/blood-2021-152528
Published: 2021
Journal Articles

Characterization of Atypical t(11;14) CCND1/IGH Translocations in Multiple Myeloma

James B Smadbeck, Neeraj Sharma, Nadine Abdallah, Hongwei Tang, Moritz Binder, Rafael Fonseca, P. Leif Bergsagel, Jess F Peterson, Rhett P. Ketterling, Patricia Greipp, S. Vincent Rajkumar, Shaji Kumar, Linda B Baughn
Journal: Blood
Blood (2021) 138 (Supplement 1): 3771.
https://doi.org/10.1182/blood-2021-150569
Published: 2021
Journal Articles

Establishing a Novel Pipeline That Combines in-Silico Prediction with in-Vitro and Ex-Vivo V alidation to Discover Secondary Drug Combinations Against Relapsed and/or Refractory Multiple Myeloma

Sayak Chakravarti, Suman Mazumder, Harish Kumar, Neeraj Sharma, Ujjal Kumar Mukherjee, Shaji Kumar, Linda B Baughn, Brian G. Van Ness, Amit Kumar Mitra
Journal: Blood
Blood (2021) 138 (Supplement 1): 1615.
https://doi.org/10.1182/blood-2021-154521
Published: 2021
Journal Articles

The Prognostic Significance of Acquired 1q22 Gain in Multiple Myeloma

Hadiyah Y. Audil, MD, Joselle Cook, MBBS, Patricia Greipp, DO, Prashant Kapoor, MD, Linda B Baughn, PhD, Angela Dispenzieri, MD, Morie A Gertz, MD, Francis K. Buadi, MB, CHB, Martha Q. Lacy, MD, David Dingli, MD PhD, Amie Fonder, PA-C, MS, Suzanne R. Hayman, MD, Miriam A. Hobbs, APRN, CNP, DNP, Eli Muchtar, MD, Mustaqeem A. Siddiqui, MDMBA, Wilson I Gonsalves, MD, Yi L. Hwa, NP, Nelson Leung, MD, Ronald S. Go, MD, Yi Lin, MD PhD, Taxiarchis Kourelis, MD, Rahma M Warsame, MD, John A. Lust, MD PhD, Robert A. Kyle, MD, Rhett P. Ketterling, MD, S. Vincent Rajkumar, MD, Shaji K. Kumar, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 9–10.
https://doi.org/10.1182/blood-2020-139093
Published: 2020
Journal Articles

Clinical Value of Next Generation Sequencing in the Detection of Recurring Structural Rearrangements and Copy Number Abnormalities in Acute Myeloid Leukemia

Beth A Pitel, MS, Neeraj Sharma, PhD, Cinthya Zepeda-Mendoza, PhD, James B Smadbeck, PhD, Kathryn E. Pearce, MS, Stephanie A. Smoley, BA, Joselle Cook, MBBS, George Vasmatzis, PhD, Zohar Sachs, MD PhD, David S. Viswanatha, MD, Robert Jenkins, MD PhD, Xinjie Xu, PhD, Sheng Xiao, MD, Nicole Hoppman, PhD, Rhett P. Ketterling, MD, Jess Peterson, MD, Patricia Greipp, DO, Linda B Baughn, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 21–22.
https://doi.org/10.1182/blood-2020-139691
Published: 2020