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Journal Articles

Alloengraftment without significant toxicity or GVHD in CD45 antibody-drug conjugate–conditioned Fanconi anemia mice

Blood (2024) 143 (21): 2201–2216.

https://doi.org/10.1182/blood.2023023549

Published: 2024

Includes: Supplemental data

Journal Articles

Prevention of acute GVHD using an orthogonal IL-2/IL-2Rβ system to selectively expand regulatory T cells in vivo

Blood (2023) 141 (11): 1337–1352.

https://doi.org/10.1182/blood.2022018440

Published: 2023

Includes: Supplemental data

Journal Articles

Engineering T cells to suppress acute GVHD and leukemia relapse after allogeneic hematopoietic stem cell transplantation

Feiyan Mo, Norihiro Watanabe, Kayleigh I. Omdahl, Phillip M. Burkhardt, Xiaoyun Ding, Eiko Hayase, Angela Panoskaltsis-Mortari, Robert R. Jenq, Helen E. Heslop, Leslie S. Kean, Malcolm K. Brenner, Victor Tkachev, Maksim Mamonkin

Blood (2023) 141 (10): 1194–1208.

https://doi.org/10.1182/blood.2022016052

Published: 2023

Includes: Supplemental data

Journal Articles

BET-bromodomain and EZH2 inhibitor–treated chronic GVHD mice have blunted germinal centers with distinct transcriptomes

Blood (2022) 139 (19): 2983–2997.

https://doi.org/10.1182/blood.2021014557

Published: 2022

Includes: Supplemental data

Journal Articles

A CD45-targeted antibody-drug conjugate successfully conditions for allogeneic hematopoietic stem cell transplantation in mice

Asim Saha, Sharon Hyzy, Tahirih Lamothe, Katelyn Hammond, Nicholas Clark, Leanne Lanieri, Prashant Bhattarai, Rahul Palchaudhuri, Geoffrey O. Gillard, Jennifer Proctor, Megan J. Riddle, Angela Panoskaltsis-Mortari, Margaret L. MacMillan, John E. Wagner, Hans-Peter Kiem, Lisa M. Olson, Bruce R. Blazar

Blood (2022) 139 (11): 1743–1759.

https://doi.org/10.1182/blood.2021012366

Published: 2022

Includes: Supplemental data

Journal Articles

Validation of Amphiregulin As a Monitoring Biomarker during Treatment of Life-Threatening Acute Gvhd: A Secondary Analysis of 2 Prospective Clinical Trials

Michael A. Pratta, Najla H El Jurdi, Armin Rashidi, Brian C. Betts, John P Galvin, Margaret L. MacMillan, Daniel J. Weisdorf, Angela Panoskaltsis-Mortari, Shernan G Holtan

Blood (2021) 138 (Supplement 1): 259.

https://doi.org/10.1182/blood-2021-150867

Published: 2021

Journal Articles

Phase 2 Results of Urinary-Derived Human Chorionic Gonadotropin/Epidermal Growth Factor As Treatment for Life-Threatening Acute Gvhd

Blood (2021) 138 (Supplement 1): 261.

https://doi.org/10.1182/blood-2021-145008

Published: 2021

Journal Articles

Repurposing a novel anti-cancer RXR agonist to attenuate murine acute GVHD and maintain graft-versus-leukemia responses

Blood (2021) 137 (8): 1090–1103.

https://doi.org/10.1182/blood.2020005628

Published: 2021

Includes: Supplemental data

Journal Articles

Plasma Short Chain Fatty Acids As a Predictor of Response to Therapy for Life-Threatening Acute Graft-Versus-Host Disease

Parth Gandhi, Isha Gandhi, Andrea Hoeschen, Wes Mosher, Margaret L. MacMillan, MD, Armin Rashidi, MD PhD, Najla H El Jurdi, MD, Alexander Khoruts, MD, Daniel J. Weisdorf, MD, Bruce R. Blazar, MD, Qing Cao, MS, Brian C. Betts, MD, Angela Panoskaltsis-Mortari, PhD, Chi Chen, Shernan G Holtan, MD

Blood (2020) 136 (Supplement 1): 14.

https://doi.org/10.1182/blood-2020-140117

Published: 2020

Journal Articles

Inhibition of inositol kinase B controls acute and chronic graft-versus-host disease

Blood (2020) 135 (1): 28–40.

https://doi.org/10.1182/blood.2019000032

Published: 2020

Includes: Supplemental data

Journal Articles

Associations between Persistent Inflammation and Oxidative Stress with Neurocognitive Impairment in Long-Term Hodgkin Lymphoma Survivors and Community Controls

AnnaLynn M Williams, PhD, Daniel A. Mulrooney, MDMS, Wei Liu, PhD, Matt J. Ehrhardt, MD MS, Sedigheh Mirzaei Salehabadi, PhD, Angela Panoskaltsis-Mortari, PhD, Deokumar Srivastava, PhD, Yutaka Yasui, PhD, Melissa M. Hudson, MD, Leslie L. Robison, PhD, Noah D Sabin, MD JD, Kevin R. Krull, PhD

Blood (2019) 134 (Supplement_1): 3479.

https://doi.org/10.1182/blood-2019-126041

Published: 2019

Journal Articles

Facilitating Resolution of Life-Threatening Acute Graft-Versus-Host Disease By Supplementation of Human Chorionic Gonadotropin and Epidermal Growth Factor (Pregnyl): A Phase I Study

Blood (2018) 132 (Supplement 1): 71.

https://doi.org/10.1182/blood-2018-99-113564

Published: 2018

Journal Articles

Pharmacologic Blockade of Notch/Delta-like Ligand 4 Signaling Protects from Gastrointestinal Acute Graft-Versus-Host Disease in Non-Human Primates

Victor Tkachev, PhD, Frank Kuhnert, PhD, Scott N Furlan, MD, Hengqi Zheng, MD, Daniel J Hunt, Lucrezia Colonna, PhD, Judith M Carlson, BS, Agne Taraseviciute, MD PhD, Angela Panoskaltsis-Mortari, PhD, Virginia Hoglund, Kayla Betz, Alison Yu, PhD, Bruce R. Blazar, MD, Steve Carpenter, MD PhD, Olivier Harari, MD PhD, Gavin Thurston, PhD, Ivan Maillard, MD PhD, Leslie Kean, MD PhD

Blood (2018) 132 (Supplement 1): 2027.

https://doi.org/10.1182/blood-2018-99-110030

Published: 2018

Journal Articles

Amphiregulin Improves Stratification of the Refined Minnesota Acute Graft-Versus-Host Disease Risk Score: Results from BMT CTN 0302/0802

Blood (2017) 130 (Supplement 1): 72.

https://doi.org/10.1182/blood.V130.Suppl_1.72.72

Published: 2017

Journal Articles

Invariant natural killer T cells ameliorate murine chronic GVHD by expanding donor regulatory T cells

Jing Du, Katelyn Paz, Govindarajan Thangavelu, Dominik Schneidawind, Jeanette Baker, Ryan Flynn, Omar Duramad, Colby Feser, Angela Panoskaltsis-Mortari, Robert S. Negrin, Bruce R. Blazar

Blood (2017) 129 (23): 3121–3125.

https://doi.org/10.1182/blood-2016-11-752444

Published: 2017

Journal Articles

Pirfenidone ameliorates murine chronic GVHD through inhibition of macrophage infiltration and TGF-β production

Blood (2017) 129 (18): 2570–2580.

https://doi.org/10.1182/blood-2017-01-758854

Published: 2017

Includes: Supplemental data

Journal Articles

Haploidentical Natural Killer Cell Infusion Induces Remission in Non-Hodgkin Lymphoma and Overcomes Resistance to Rituximab

Veronika Bachanova, MD, Dhifaf Sarhan, PhD, Todd E. DeFor, MS, Sarah Cooley, MD, Angela Panoskaltsis-Mortari, PhD, Michael R. Verneris, MD, Bruce R. Blazar, MD, Julie Curtsinger, PhD, Linda J. Burns, MD, Daniel J. Weisdorf, MD, Jeffrey S. Miller, MD

Blood (2016) 128 (22): 3030.

https://doi.org/10.1182/blood.V128.22.3030.3030

Published: 2016

Journal Articles

Pirfenidone Reverses Murine Chronic Graft Versus Host Disease

Jing Du, Ryan P Flynn, PhD, Katelyn Paz, Ante Vulic, MD, Tara M. Robinson, MD PhD, Katie E Lineburg, BSc, Kelli P A Macdonald, PhD, Geoffrey R Hill, Jonathan S Serody, MD, Ivan Maillard, MD PhD, Angela Panoskaltsis-Mortari, PhD, Timothy Schacker, MD, Leo Luznik, MD, Bruce R. Blazar, MD

Blood (2016) 128 (22): 1158.

https://doi.org/10.1182/blood.V128.22.1158.1158

Published: 2016

Journal Articles

Striking Clinical, Molecular and Immunological Outcomes in Non-Human Primate Hematopoietic Stem Cell Transplantation Using a Novel OX40L Blockade Agent, KY1005, Combined with Rapamycin

Victor Tkachev, PhD, Scott N. Furlan, MD, Ben Watkins, MD, Betty Zheng, MD, Daniel Hunt, Angela Panoskaltsis-Mortari, PhD, Kayla Betz, Melanie Brown, Katie Zeleski, Alison Yu, PhD, Bruce R. Blazar, MD, Duncan Casson, Ian Kirby, Phil Bland-Ward, Leslie Kean, MD PhD

Blood (2016) 128 (22): 3341.

https://doi.org/10.1182/blood.V128.22.3341.3341

Published: 2016

Journal Articles

Critical Roles of Retinoic Acid Signaling in Combating Acute Graft Versus Host Disease

Govindarajan Thangavelu, PhD, Asim Saha, PhD, Kazutoshi Aoyama, MD PhD, Cameron McDonald-Hyman, BA, Yu-Chi Lee, MSc, Chrysothemis Brown, MBBS, PhD, Angela Panoskaltsis-Mortari, PhD, Mark J. Osborn, PhD, Roshantha A Chandraratna, PhD, Randolph Noelle, PhD, Bruce R. Blazar, MD

Blood (2016) 128 (22): 4534.

https://doi.org/10.1182/blood.V128.22.4534.4534

Published: 2016

NARROW

Alloengraftment without significant toxicity or GVHD in CD45 antibody-drug conjugate–conditioned Fanconi anemia mice

Prevention of acute GVHD using an orthogonal IL-2/IL-2Rβ system to selectively expand regulatory T cells in vivo

Engineering T cells to suppress acute GVHD and leukemia relapse after allogeneic hematopoietic stem cell transplantation

BET-bromodomain and EZH2 inhibitor–treated chronic GVHD mice have blunted germinal centers with distinct transcriptomes

A CD45-targeted antibody-drug conjugate successfully conditions for allogeneic hematopoietic stem cell transplantation in mice

Validation of Amphiregulin As a Monitoring Biomarker during Treatment of Life-Threatening Acute Gvhd: A Secondary Analysis of 2 Prospective Clinical Trials

Phase 2 Results of Urinary-Derived Human Chorionic Gonadotropin/Epidermal Growth Factor As Treatment for Life-Threatening Acute Gvhd

Repurposing a novel anti-cancer RXR agonist to attenuate murine acute GVHD and maintain graft-versus-leukemia responses

Plasma Short Chain Fatty Acids As a Predictor of Response to Therapy for Life-Threatening Acute Graft-Versus-Host Disease

Inhibition of inositol kinase B controls acute and chronic graft-versus-host disease

Associations between Persistent Inflammation and Oxidative Stress with Neurocognitive Impairment in Long-Term Hodgkin Lymphoma Survivors and Community Controls

Facilitating Resolution of Life-Threatening Acute Graft-Versus-Host Disease By Supplementation of Human Chorionic Gonadotropin and Epidermal Growth Factor (Pregnyl): A Phase I Study

Pharmacologic Blockade of Notch/Delta-like Ligand 4 Signaling Protects from Gastrointestinal Acute Graft-Versus-Host Disease in Non-Human Primates

Amphiregulin Improves Stratification of the Refined Minnesota Acute Graft-Versus-Host Disease Risk Score: Results from BMT CTN 0302/0802

Invariant natural killer T cells ameliorate murine chronic GVHD by expanding donor regulatory T cells

Pirfenidone ameliorates murine chronic GVHD through inhibition of macrophage infiltration and TGF-β production

Haploidentical Natural Killer Cell Infusion Induces Remission in Non-Hodgkin Lymphoma and Overcomes Resistance to Rituximab

Pirfenidone Reverses Murine Chronic Graft Versus Host Disease

Striking Clinical, Molecular and Immunological Outcomes in Non-Human Primate Hematopoietic Stem Cell Transplantation Using a Novel OX40L Blockade Agent, KY1005, Combined with Rapamycin

Critical Roles of Retinoic Acid Signaling in Combating Acute Graft Versus Host Disease

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American Society of Hematology

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American Society of Hematology

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