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Connor McGuckin
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Journal Articles

B-cell–directed CAR T-cell therapy activates CD8 + cytotoxic CAR neg bystander T cells in patients and nonhuman primates

James Kaminski, Ryan A. Fleming, Francesca Alvarez-Calderon, Marlana B. Winschel, Connor McGuckin, Emily E. Ho, Fay Eng, Xianliang Rui, Paula Keskula, Lorenzo Cagnin, Joanne Charles, Jillian Zavistaski, Steven P. Margossian, Malika A. Kapadia, James B. Rottman, Jennifer Lane, Susanne H. C. Baumeister, Victor Tkachev, Alex K. Shalek, Leslie S. Kean, Ulrike Gerdemann
Journal: Blood
Blood (2024) 144 (1): 46–60.
https://doi.org/10.1182/blood.2023022717
Published: 2024
Includes: Supplemental data
Journal Articles

CAR-T Cell Infusion Results in Activation of CD160+/NKG2D+/CCL5+ Non-CAR CD8+ Cytotoxic 'Bystander' T Cells in Both Non-Human Primates (NHP) and Patients Receiving B-Cell-Directed CAR-Ts

Ulrike Gerdemann, James Kaminski, Ryan A Fleming, Victor Tkachev, Francesca Alvarez Calderon, Connor McGuckin, Xianliang Rui, Jennifer Lane, Alex K. Shalek, Leslie Kean
Journal: Blood
Blood (2022) 140 (Supplement 1): 1167–1168.
https://doi.org/10.1182/blood-2022-169435
Published: 2022
Journal Articles

A Novel Human OX40L-CAR-Treg Specifically Targets Activated Antigen-Presenting Cells and Effectively Controls T Cell Alloreactivity and Xeno-GvHD

Xianliang Rui, Francesca Alvarez Calderon, Ulrike Gerdemann, Connor McGuckin, Lorenzo Cagnin, Bruce R. Blazar, Victor Tkachev, Leslie S. Kean
Journal: Blood
Blood (2022) 140 (Supplement 1): 871–872.
https://doi.org/10.1182/blood-2022-165745
Published: 2022
Journal Articles

ZNF410 Represses Fetal Globin By Devoted Control of CHD4/NuRD

Divya S Vinjamur, PhD, Qiuming Yao, PhD, Mitchel A. Cole, BS, Connor McGuckin, Chunyan Ren, PhD, Jing Zeng, MD, Mir Hossain, PhD, Luca Pinello, PhD, Daniel E Bauer, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 1.
https://doi.org/10.1182/blood-2020-142134
Published: 2020
Journal Articles

Synthetic Lethality of Wnt Pathway Activation and Asparaginase in Drug-Resistant Acute Leukemias

Laura Hinze, Maren Pfirrmann, Salmaan Karim, James Degar, Connor McGuckin, Divya Vinjamur, PhD, Sacher Joshua, Kristen E. Stevenson, MS, Donna S Neuberg, ScD, Daniel E. Bauer, MD PhD, Florence Wagner, PhD, Kimberly Stegmaier, MD, Alejandro Gutierrez, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 891.
https://doi.org/10.1182/blood-2018-99-113794
Published: 2018