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Brent H. Koehn
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Journal Articles

Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GVHD

Brent H. Koehn, Asim Saha, Cameron McDonald-Hyman, Michael Loschi, Govindarajan Thangavelu, Lie Ma, Michael Zaiken, Josh Dysthe, Walker Krepps, Jamie Panthera, Keli Hippen, Stephen C. Jameson, Jeffrey S. Miller, Matthew A. Cooper, Christopher J. Farady, Takao Iwawaki, Jenny P.-Y. Ting, Jonathan S. Serody, William J. Murphy, Geoffrey R. Hill, Peter J. Murray, Vincenzo Bronte, David H. Munn, Robert Zeiser, Bruce R. Blazar
Journal: Blood
Blood (2019) 134 (19): 1670–1682.
https://doi.org/10.1182/blood.2019001950
Published: 2019
Journal Articles

Peri-alloHCT IL-33 administration expands recipient T-regulatory cells that protect mice against acute GVHD

Benjamin M. Matta, Dawn K. Reichenbach, Xiaoli Zhang, Lisa Mathews, Brent H. Koehn, Gaelen K. Dwyer, Jeremy M. Lott, Franziska M. Uhl, Dietmar Pfeifer, Colby J. Feser, Michelle J. Smith, Quan Liu, Robert Zeiser, Bruce R. Blazar, Hēth R. Turnquist
Journal: Blood
Blood (2016) 128 (3): 427–439.
https://doi.org/10.1182/blood-2015-12-684142
Published: 2016
Includes: Supplemental data
Journal Articles

Protein Kinase C-Theta Interacts with mTORC2 and Vimentin to Limit Regulatory T-Cell Function

Cameron McDonald-Hyman, BA, Govindarajan Thangavelu, PhD, James Muller, Guoan Zhang, PhD, Sudha Kumari, PhD, Asim Saha, PhD, Brent H. Koehn, PhD, Jason S. Mitchell, PhD, Brian T Fife, PhD, Jonathan S. Serody, MD, Mark J. Osborn, PhD, Keli L. Hippen, PhD, Ameeta Kelekar, PhD, David H. Munn, MD, Amnon Altman, PhD, Thomas A. Neubert, PhD, Michael L. Dustin, PhD, Bruce R. Blazar, MD
Journal: Blood
Blood (2015) 126 (23): 849.
https://doi.org/10.1182/blood.V126.23.849.849
Published: 2015
Journal Articles

GVHD-associated, inflammasome-mediated loss of function in adoptively transferred myeloid-derived suppressor cells

Brent H. Koehn, Petya Apostolova, Jessica M. Haverkamp, Jeffrey S. Miller, Valarie McCullar, Jakub Tolar, David H. Munn, William J. Murphy, Willie June Brickey, Jonathan S. Serody, Dmitry I. Gabrilovich, Vincenzo Bronte, Peter J. Murray, Jenny P.-Y. Ting, Robert Zeiser, Bruce R. Blazar
Journal: Blood
Blood (2015) 126 (13): 1621–1628.
https://doi.org/10.1182/blood-2015-03-634691
Published: 2015
Includes: Supplemental data
Journal Articles

The IL-33/ST2 axis augments effector T-cell responses during acute GVHD

Dawn K. Reichenbach, Vincent Schwarze, Benjamin M. Matta, Victor Tkachev, Elisabeth Lieberknecht, Quan Liu, Brent H. Koehn, Dietmar Pfeifer, Patricia A. Taylor, Gabriele Prinz, Heide Dierbach, Natalie Stickel, Yvonne Beck, Max Warncke, Tobias Junt, Annette Schmitt-Graeff, Susumu Nakae, Marie Follo, Tobias Wertheimer, Lukas Schwab, Jason Devlin, Simon C. Watkins, Justus Duyster, James L. M. Ferrara, Heth R. Turnquist, Robert Zeiser, Bruce R. Blazar
Journal: Blood
Blood (2015) 125 (20): 3183–3192.
https://doi.org/10.1182/blood-2014-10-606830
Published: 2015
Includes: Supplemental data
Journal Articles

Regulation of Immune Responses during Acute GvHD Via the IL-33/ST2 Axis

Dawn K Reichenbach, PhD, Vincent Schwarze, Benjamin M Matta, PhD, Victor Tkachev, Elizabeth Lieberknecht, Quan Liu, MD PhD, Brent H Koehn, PhD, Dietmar Pfeifer, PhD, Patricia A Taylor, DVM, Gabriele Prinz, Heide Dierbach, Natalie Stickel, MS, Yvonne Beck, Max Warncke, Tobias Junt, Annette Schmitt-Graeff, MD, Susumu Nakae, Marie Follo, PhD, Tobias Wertheimer, Lukas Schwab, Jason Devlin, Simon C Watkins, PhD, Justus Duyster, James L.M. Ferrara, MD, D.Sc., Heth R. Turnquist, PhD, Robert Zeiser, Bruce R. Blazar, MD
Journal: Blood
Blood (2014) 124 (21): 844.
https://doi.org/10.1182/blood.V124.21.844.844
Published: 2014
Journal Articles

Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in regulating graft-versus-host disease lethality

Asim Saha, Kazutoshi Aoyama, Patricia A. Taylor, Brent H. Koehn, Rachelle G. Veenstra, Angela Panoskaltsis-Mortari, David H. Munn, William J. Murphy, Miyuki Azuma, Hideo Yagita, Brian T. Fife, Mohammed H. Sayegh, Nader Najafian, Gerard Socie, Rafi Ahmed, Gordon J. Freeman, Arlene H. Sharpe, Bruce R. Blazar
Journal: Blood
Blood (2013) 122 (17): 3062–3073.
https://doi.org/10.1182/blood-2013-05-500801
Published: 2013
Includes: Supplemental data
Journal Articles

Bone marrow myeloid-derived suppressor cells (MDSCs) inhibit graft-versus-host disease (GVHD) via an arginase-1–dependent mechanism that is up-regulated by interleukin-13

Steven L. Highfill, Paulo C. Rodriguez, Qing Zhou, Christine A. Goetz, Brent H. Koehn, Rachelle Veenstra, Patricia A. Taylor, Angela Panoskaltsis-Mortari, Jonathan S. Serody, David H. Munn, Jakub Tolar, Augusto C. Ochoa, Bruce R. Blazar
Journal: Blood
Blood (2010) 116 (25): 5738–5747.
https://doi.org/10.1182/blood-2010-06-287839
Published: 2010
Includes: Supplemental data