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Journal Articles

GVHD-associated, inflammasome-mediated loss of function in adoptively transferred myeloid-derived suppressor cells

Brent H. Koehn, Petya Apostolova, Jessica M. Haverkamp, Jeffrey S. Miller, Valarie McCullar, Jakub Tolar, David H. Munn, William J. Murphy, Willie June Brickey, Jonathan S. Serody, Dmitry I. Gabrilovich, Vincenzo Bronte, Peter J. Murray, Jenny P.-Y. Ting, Robert Zeiser, Bruce R. Blazar

Blood (2015) 126 (13): 1621–1628.

https://doi.org/10.1182/blood-2015-03-634691

Published: 2015

Includes: Supplemental data

Journal Articles

Optimal Xenogeneic Adoptive Transfer of Human NK Cells: Fresh NK Cells and IL-15 Administration Are Superior to Frozen NK Cells and IL-2

Jakub Tolar, MD, PhD, Julie Curtsinger, PhD, Ron McElmurry, Valarie McCullar, Michael R. Verneris, MD, Frits van Rhee, MD, PhD, Natalia Lapteva, Cliona M Rooney, PhD, John E. Wagner, MD, Bruce R. Blazar, MD, Jeffrey S. Miller, MD

Blood (2012) 120 (21): 346.

https://doi.org/10.1182/blood.V120.21.346.346

Published: 2012

Journal Articles

Tim-3 is an inducible human natural killer cell receptor that enhances interferon gamma production in response to galectin-9

Michelle K. Gleason, Todd R. Lenvik, Valarie McCullar, Martin Felices, M. Shea O'Brien, Sarah A. Cooley, Michael R. Verneris, Frank Cichocki, Carol J. Holman, Angela Panoskaltsis-Mortari, Toshiro Niki, Mitsuomi Hirashima, Bruce R. Blazar, Jeffrey S. Miller

Blood (2012) 119 (13): 3064–3072.

https://doi.org/10.1182/blood-2011-06-360321

Published: 2012

Includes: Supplemental data

Journal Articles

IL-2 Stimulated Treg Inhibit in Vitro Expansion of Haploidentical Natural Killer (NK) Cells, Which Is Partially Overcome with An IL-2-Diphtheria Toxin Fusion Protein In Vivo,

Sarah Cooley, MD, Veronika Bachanova, Melissa Geller, MD, Michael R Verneris, MD, Bin Zhang, Valarie McCullar, David McKenna, MD, Dixie Lewis, Angela Panoskaltsis-Mortari, PhD, Daniel J. Weisdorf, MD, Philip McGlave, MD, Keli Hippen, Bruce R. Blazar, MD, Jeffrey S. Miller, MD

Blood (2011) 118 (21): 3611.

https://doi.org/10.1182/blood.V118.21.3611.3611

Published: 2011

Journal Articles

Tim-3, a Novel Immune Receptor, Is Constitutively Expressed on Human Natural Killer Cells and Functions as An Activating Coreceptor

Michelle Gleason, Todd Lenvik, Valarie McCullar, Sarah Cooley, MD, Michael Verneris, MD, Toshiro Niki, Mitsuomi Hirashima, Bruce R. Blazar, MD, Jeffrey S. Miller, MD

Blood (2010) 116 (21): 106.

https://doi.org/10.1182/blood.V116.21.106.106

Published: 2010

Journal Articles

The transcription factor c-Myc enhances KIR gene transcription through direct binding to an upstream distal promoter element

Frank Cichocki, Rebecca J. Hanson, Todd Lenvik, Michelle Pitt, Valarie McCullar, Hongchuan Li, Stephen K. Anderson, Jeffrey S. Miller

Blood (2009) 113 (14): 3245–3253.

https://doi.org/10.1182/blood-2008-07-166389

Published: 2009

Journal Articles

Blocking Inhibitory KIR Is Insufficient for Optimal Killing of AML and ALL Targets: Additional Requirements for NKG2A and LIR-1 Blockade

Robert Godal, Michelle Gleason, Valarie McCullar, Sarah Cooley, MD, Veronika Bachanova, Michael Verneris, MD, Philip McGlave, MD, Jeffrey S. Miller, MD

Blood (2008) 112 (11): 2906.

https://doi.org/10.1182/blood.V112.11.2906.2906

Published: 2008

Journal Articles

Successful Haploidentical Hematopoietic Cell Engraftment Using a Non-Myeloablative Preparative Regimen Including Natural Killer (NK) Cells

Sarah Cooley, Purvi Gada, David McKenna, Valarie McCullar, Susan Fautsch, Michael Verneris, Bruce R Blazar, Linda J Burns, Philip B McGlave, MD, Daniel J. Weisdorf, Jeffrey S Miller

Blood (2008) 112 (11): 827.

https://doi.org/10.1182/blood.V112.11.827.827

Published: 2008

Journal Articles

Killer Immunoglobulin Receptor (KIR) Negative NK Cells Exhibit Potent Alloreactivity Against Primary Leukemia Targets When Interrupting MHC Class I Interactions through NKG2A Blockade.

Robert Godal, MD, Michelle Gleason, Valarie McCullar, Sarah Cooley, MD, Michael Verneris, MD, Philip McGlave, MD, Jeffrey S. Miller, MD

Blood (2007) 110 (11): 2862.

https://doi.org/10.1182/blood.V110.11.2862.2862

Published: 2007

Journal Articles

The unexpected effect of cyclosporin A on CD56 + CD16 − and CD56 + CD16 + natural killer cell subpopulations

Hongbo Wang, Bartosz Grzywacz, David Sukovich, Valarie McCullar, Qing Cao, Alisa B. Lee, Bruce R. Blazar, David N. Cornfield, Jeffrey S. Miller, Michael R. Verneris

Blood (2007) 110 (5): 1530–1539.

https://doi.org/10.1182/blood-2006-10-048173

Published: 2007

Journal Articles

A subpopulation of human peripheral blood NK cells that lacks inhibitory receptors for self-MHC is developmentally immature

Sarah Cooley, Feng Xiao, Michelle Pitt, Michelle Gleason, Valarie McCullar, Tracy L. Bergemann, Karina L. McQueen, Lisbeth A. Guethlein, Peter Parham, Jeffrey S. Miller

Blood (2007) 110 (2): 578–586.

https://doi.org/10.1182/blood-2006-07-036228

Published: 2007

Includes: Supplemental data

Journal Articles

Optimal NK Cell Expansion Depends on Accessory Cells, Synergy between Physiologic Concentrations of IL-2 and IL-15, and Umbilical Cord Blood (UCB) NK Cell Precursors Expand Better Than Adult NK Cells.

Purvi Gada, MBBS, Michelle Gleason, Valarie McCullar, Philip B. McGlave, MD, Jeffrey S. Miller, MD

Blood (2006) 108 (11): 3642.

https://doi.org/10.1182/blood.V108.11.3642.3642

Published: 2006

Journal Articles

A Subpopulation of Human NK Cells Lacking Inhibitory Receptors for Self MHC Is Developmentally Immature Rather Than Autoreactive.

Sarah Cooley, MD, Feng Xiao, PhD, Michelle Pitt, Michelle Gleason, Valarie McCullar, Tracy Bergemann, Karina McQueen, Lisbeth Guethlein, Peter Parham, PhD, Jeffrey S. Miller, MD

Blood (2006) 108 (11): 918.

https://doi.org/10.1182/blood.V108.11.918.918

Published: 2006

Journal Articles

Notch Activation in Cord Blood Progenitors Induces a CD7+ Common NK/T Precursor Capable of NK Cell Commitment without Full Maturation and Differentiation of Lineage Committed Pre-T Lymphocytes with a Th1 Phenotype.

Veronika Bachanova, MD, Valarie McCullar, Rosanna Wangen, Jeffrey S. Miller

Blood (2006) 108 (11): 644.

https://doi.org/10.1182/blood.V108.11.644.644

Published: 2006

Journal Articles

KIR reconstitution is altered by T cells in the graft and correlates with clinical outcomes after unrelated donor transplantation

Sarah Cooley, Valarie McCullar, Rosanna Wangen, Tracy L. Bergemann, Stephen Spellman, Daniel J. Weisdorf, Jeffrey S. Miller

Blood (2005) 106 (13): 4370–4376.

https://doi.org/10.1182/blood-2005-04-1644

Published: 2005

Journal Articles

The Unexpected and Differential Effect of Cyclosporin A on CD56 Bright and CD56 Dim NK Cell Expansion, Phenotype, Function and Development from Progenitor Cells.

Hongbo Wang, MD, PhD, Alisa Lee, Valarie McCullar, Bruce R. Blazar, MD, Jeffery S. Miller, MD, Michael R. Verneris, MD

Blood (2005) 106 (11): 1404.

https://doi.org/10.1182/blood.V106.11.1404.1404

Published: 2005

Journal Articles

NK Cell KIR Reconstitution after Allogeneic Hematopoietic Cell Transplant (HCT) Is Affected by T Cell Number and Function.

Sarah Cooley, Valarie McCullar, Rosanna Wangen, Tracy L. Bergemann, PhD, John E. Wagner, MD, Daniel J. Weisdorf, MD, Philip McGlave, MD, Jeffrey S. Miller, MD

Blood (2005) 106 (11): 1406.

https://doi.org/10.1182/blood.V106.11.1406.1406

Published: 2005

Journal Articles

Understanding the Membrane Proteome of Developing Natural Killer Cells.

Troy Lund, Valarie McCullar, Lorraine B. Anderson, Jeffrey S. Miller, MD

Blood (2005) 106 (11): 3316.

https://doi.org/10.1182/blood.V106.11.3316.3316

Published: 2005

Journal Articles

Murine Embryonic Liver Differentiates Human Stem Cells into a Spectrum of NK Precursors and Polyclonal KIR Expressing NK Cells.

Jeffrey S. Miller, MD, Karen Brungaard, Robert A.J. Oostendorp, MD, Valarie McCullar

Blood (2005) 106 (11): 3317.

https://doi.org/10.1182/blood.V106.11.3317.3317

Published: 2005

Journal Articles

C-MYC Induces KIR Expression Via a Novel Control Region Upstream of the Conventional Adult KIR Promoter.

Becky Haack, Valarie McCullar, Todd Lenvik, Michelle Pitt, Stephen Anderson, PhD, Jeffrey S. Miller, MD

Blood (2005) 106 (11): 764.

https://doi.org/10.1182/blood.V106.11.764.764

Published: 2005

NARROW

GVHD-associated, inflammasome-mediated loss of function in adoptively transferred myeloid-derived suppressor cells

Optimal Xenogeneic Adoptive Transfer of Human NK Cells: Fresh NK Cells and IL-15 Administration Are Superior to Frozen NK Cells and IL-2

Tim-3 is an inducible human natural killer cell receptor that enhances interferon gamma production in response to galectin-9

IL-2 Stimulated Treg Inhibit in Vitro Expansion of Haploidentical Natural Killer (NK) Cells, Which Is Partially Overcome with An IL-2-Diphtheria Toxin Fusion Protein In Vivo,

Tim-3, a Novel Immune Receptor, Is Constitutively Expressed on Human Natural Killer Cells and Functions as An Activating Coreceptor

The transcription factor c-Myc enhances KIR gene transcription through direct binding to an upstream distal promoter element

Blocking Inhibitory KIR Is Insufficient for Optimal Killing of AML and ALL Targets: Additional Requirements for NKG2A and LIR-1 Blockade

Successful Haploidentical Hematopoietic Cell Engraftment Using a Non-Myeloablative Preparative Regimen Including Natural Killer (NK) Cells

Killer Immunoglobulin Receptor (KIR) Negative NK Cells Exhibit Potent Alloreactivity Against Primary Leukemia Targets When Interrupting MHC Class I Interactions through NKG2A Blockade.

The unexpected effect of cyclosporin A on CD56 + CD16 − and CD56 + CD16 + natural killer cell subpopulations

A subpopulation of human peripheral blood NK cells that lacks inhibitory receptors for self-MHC is developmentally immature

Optimal NK Cell Expansion Depends on Accessory Cells, Synergy between Physiologic Concentrations of IL-2 and IL-15, and Umbilical Cord Blood (UCB) NK Cell Precursors Expand Better Than Adult NK Cells.

A Subpopulation of Human NK Cells Lacking Inhibitory Receptors for Self MHC Is Developmentally Immature Rather Than Autoreactive.

Notch Activation in Cord Blood Progenitors Induces a CD7+ Common NK/T Precursor Capable of NK Cell Commitment without Full Maturation and Differentiation of Lineage Committed Pre-T Lymphocytes with a Th1 Phenotype.

KIR reconstitution is altered by T cells in the graft and correlates with clinical outcomes after unrelated donor transplantation

The Unexpected and Differential Effect of Cyclosporin A on CD56 Bright and CD56 Dim NK Cell Expansion, Phenotype, Function and Development from Progenitor Cells.

NK Cell KIR Reconstitution after Allogeneic Hematopoietic Cell Transplant (HCT) Is Affected by T Cell Number and Function.

Understanding the Membrane Proteome of Developing Natural Killer Cells.

Murine Embryonic Liver Differentiates Human Stem Cells into a Spectrum of NK Precursors and Polyclonal KIR Expressing NK Cells.

C-MYC Induces KIR Expression Via a Novel Control Region Upstream of the Conventional Adult KIR Promoter.

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American Society of Hematology

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American Society of Hematology

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