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Journal Articles

Analysis of the T-cell repertoire and transcriptome identifies mechanisms of regulatory T-cell suppression of GVHD

Juliane K. Lohmeyer, Toshihito Hirai, Mustafa Turkoz, Stephane Buhler, Teresa Lopes Ramos, Natalie Köhler, Jeanette Baker, Astrid Melotti, Ingrid Wagner, Amandine Pradier, Sisi Wang, Xuhuai Ji, Simone Becattini, Jean Villard, Doron Merkler, Yves Chalandon, Robert S. Negrin, Federico Simonetta

Blood (2023) 141 (14): 1755–1767.

https://doi.org/10.1182/blood.2022017982

Published: 2023

Includes: Supplemental data

Journal Articles

Prevention of acute GVHD using an orthogonal IL-2/IL-2Rβ system to selectively expand regulatory T cells in vivo

Blood (2023) 141 (11): 1337–1352.

https://doi.org/10.1182/blood.2022018440

Published: 2023

Includes: Supplemental data

Journal Articles

Prevention of Acute Graft-Versus-Host Disease Using an Engineered Mouse Orthogonal IL-2/IL-2Rβ Regulatory T Cells

Teresa Lopes Ramos, Sara B. Wagers, Po-Yu Lin, Toshihito Hirai, Leon Su, Lora Picton, Jeanette Baker, Juliane Lohmeyer, Melissa Mavers, Christopher Garcia, Bruce R. Blazar, Robert S. Negrin

Blood (2021) 138 (Supplement 1): 1688.

https://doi.org/10.1182/blood-2021-154123

Published: 2021

Journal Articles

Invariant natural killer T-cell subsets have diverse graft-versus-host-disease–preventing and antitumor effects

Kristina Maas-Bauer, Juliane K. Lohmeyer, Toshihito Hirai, Teresa Lopes Ramos, Furqan M. Fazal, Ulrike M. Litzenburger, Kathryn E. Yost, Jessica V. Ribado, Neeraja Kambham, Arielle S. Wenokur, Po-Yu Lin, Maite Alvarez, Melissa Mavers, Jeanette Baker, Ami S. Bhatt, Howard Y. Chang, Federico Simonetta, Robert S. Negrin

Blood (2021) 138 (10): 858–870.

https://doi.org/10.1182/blood.2021010887

Published: 2021

Includes: Supplemental data

Journal Articles

RNA and TCR Sequencing Shed Light on Mechanisms of Treg Suppression in a Murine Model of Acute GvHD

Juliane K. Lohmeyer, MD, Toshihito Hirai, MD PhD, Mustafa Turkoz, PhD, Natalie Koehler, PhD, Jeanette Baker, Stephane Buhler, PhD, Jean Villard, MD PhD, Xuhuai Ji, MD PhD, Federico Simonetta, MD PhD, Robert S. Negrin, MD

Blood (2020) 136 (Supplement 1): 30.

https://doi.org/10.1182/blood-2020-137220

Published: 2020

Journal Articles

Molecular Imaging of Chimeric Antigen Receptor T Cells By ICOS-Immunopet

Blood (2020) 136 (Supplement 1): 5–6.

https://doi.org/10.1182/blood-2020-136331

Published: 2020

Journal Articles

Allogeneic Chimeric Antigen Receptor-Invariant Natural Killer T Cells Exert Both Direct and Indirect Antitumor Effects through Host CD8 T Cell Cross-Priming

Federico Simonetta, MD PhD, Toshihito Hirai, MD PhD, Juliane K. Lohmeyer, MD, Kristina Maas-Bauer, MD, Maite Alvarez, PhD, Arielle S. Wenokur, Jeanette Baker, Amin Aalipour, PhD, Samuel Haile, PhD, Crystal L. Mackall, MD, Robert S. Negrin, MD

Blood (2019) 134 (Supplement_1): 867.

https://doi.org/10.1182/blood-2019-122515

Published: 2019

Journal Articles

iNKT Cell Stimulation with Liposomal Alpha/Gal/Cer Amplifies Proliferation of Adoptively Transferred Regulatory T Cells In Vivo and Reduces GvHD

Toshihito Hirai, MD PhD, Federico Simonetta, MD PhD, Kristina Maas-Bauer, MD, Melissa Mavers, MD PhD, Jeanette Baker, Robert S. Negrin, MD

Blood (2018) 132 (Supplement 1): 4519.

https://doi.org/10.1182/blood-2018-99-109836

Published: 2018

Journal Articles

Tracking T Cell Activation By OX40 Immuno-PET: A Novel Strategy for Imaging of Graft Versus Host Disease

Federico Simonetta, MD PhD, Israt S. Alam, PhD, Aaron T. Mayer, Surya Murty, Ophir Vermesh, MD PhD, Toshihito Hirai, MD PhD, Tomomi Nobashi, MD, Kenneth Lau, Sanjiv S. Gambhir, MD PhD, Robert S. Negrin, MD

Blood (2018) 132 (Supplement 1): 4527.

https://doi.org/10.1182/blood-2018-99-116483

Published: 2018

Journal Articles

Invariant Natural Killer T Cell Subsets Have Diverse Functions: iNKT2 and iNKT17 Protect from Graft-Versus-Host-Disease, Whereas iNKT1 Have Antitumor Potential

Kristina Maas-Bauer, MD, Federico Simonetta, MD PhD, Toshihito Hirai, MD PhD, Arielle Wenokur, Furqan Fazal, PhD, Neeraja Kambham, MD, Jessica Ribado, Melissa Mavers, MD PhD, Jeanette Baker, Ami S. Bhatt, MD PhD, Howard Y. Chang, MD PhD, Robert S. Negrin, MD

Blood (2018) 132 (Supplement 1): 475.

https://doi.org/10.1182/blood-2018-99-113673

Published: 2018

Journal Articles

IL-2 Plus IL-15 Leads to Enhanced Ex Vivo Expansion of Human Invariant Natural Killer T Cells

Melissa Mavers, MD, Federico Simonetta, MD PhD, Alexander W. Lee, Toshihito Hirai, MD PhD, Kristina Maas-Bauer, MD, Jeanette Baker, PhD, Maite Alvarez, PhD, Mustafa Turkoz, PhD, Everett H. Meyer, MD PhD, Robert S. Negrin, MD

Blood (2017) 130 (Supplement 1): 3199.

https://doi.org/10.1182/blood.V130.Suppl_1.3199.3199

Published: 2017

Journal Articles

Treatment of Donors with Liposomal Alpha-Galactosylceramide Results in the In Vivo Expansion of Invariant Natural Killer T Cells and Reduced Incidence of Acute Graft Versus Host Disease

Toshihito Hirai, MD PhD, Federico Simonetta, MD PhD, Jeanette Baker, PhD, Kristina Maas-Bauer, MD, Musutafa Turkoz, Maite Alvarez, PhD, Melissa Mavers, MD, Robert S. Negrin, MD

Blood (2017) 130 (Supplement 1): 1896.

https://doi.org/10.1182/blood.V130.Suppl_1.1896.1896

Published: 2017

NARROW

Analysis of the T-cell repertoire and transcriptome identifies mechanisms of regulatory T-cell suppression of GVHD

Prevention of acute GVHD using an orthogonal IL-2/IL-2Rβ system to selectively expand regulatory T cells in vivo

Prevention of Acute Graft-Versus-Host Disease Using an Engineered Mouse Orthogonal IL-2/IL-2Rβ Regulatory T Cells

Invariant natural killer T-cell subsets have diverse graft-versus-host-disease–preventing and antitumor effects

RNA and TCR Sequencing Shed Light on Mechanisms of Treg Suppression in a Murine Model of Acute GvHD

Molecular Imaging of Chimeric Antigen Receptor T Cells By ICOS-Immunopet

Allogeneic Chimeric Antigen Receptor-Invariant Natural Killer T Cells Exert Both Direct and Indirect Antitumor Effects through Host CD8 T Cell Cross-Priming

iNKT Cell Stimulation with Liposomal Alpha/Gal/Cer Amplifies Proliferation of Adoptively Transferred Regulatory T Cells In Vivo and Reduces GvHD

Tracking T Cell Activation By OX40 Immuno-PET: A Novel Strategy for Imaging of Graft Versus Host Disease

Invariant Natural Killer T Cell Subsets Have Diverse Functions: iNKT2 and iNKT17 Protect from Graft-Versus-Host-Disease, Whereas iNKT1 Have Antitumor Potential

IL-2 Plus IL-15 Leads to Enhanced Ex Vivo Expansion of Human Invariant Natural Killer T Cells

Treatment of Donors with Liposomal Alpha-Galactosylceramide Results in the In Vivo Expansion of Invariant Natural Killer T Cells and Reduced Incidence of Acute Graft Versus Host Disease

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American Society of Hematology

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ASH Publications

American Society of Hematology

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