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Remi Letestu
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Journal Articles

Prognosis of the IGLV3-21 R110 Mutation in a Real-Life Chronic Lymphocytic Leukemia Cohort

Merieme Bensalah, Amal Messaoudi, Carole Fleury, Giulia Tueur, Rémi Letestu, Marine Armand, Sabine Brechignac, Sarah Ivanoff, Valérie Vidal, Ramy Rahmé, Chadi Al Nawakil, Thorsten Braun, Catherine Thieblemont, Cymbalista Florence, Vincent Levy, Fanny Baran-Marszak, Grégory Lazarian
Journal: Blood
Blood (2024) 144 (Supplement 1): 3241.
https://doi.org/10.1182/blood-2024-200665
Published: 2024
Journal Articles

Minimal Residual Disease-Guided Combination of Ibrutinib and Venetoclax Compared to FCR in Untreated Patients with CLL of Intermediate Risk : Final Results of the Eradic Trial from the Filo Group

Anne Sophie Michallet, Remi Letestu, Magali Legarff, Stéphane Morisset, Therese Aurran-Schleinitz, Kamel Laribi, Vincent Levy, Laurence Simon, Damien Roos Weil, Marie Sarah Dilhuydy, Cecile Tomowiak, Caroline Dartigeas, Romain Guieze, Olivier Tournilhac, Emmanuelle Ferrant, Sophie De Guibert, Pierre Feugier, Fatiha Merabet, Stéphane Lepretre, Philippe Carassou, Julie Gay, Benedicte Hivert, Luc-Matthieu Fornecker, Jehan Dupuis, Lysiane Molina, Bruno Villemagne, Guillaume Cartron, Bernard Drenou, Omar Benbrahim, Xavier Cahu, Florence Nguyen Khac, Valerie Rouillé, Loic Ysebaert, Anne Quinquenel
Journal: Blood
Blood (2024) 144 (Supplement 1): 584.
https://doi.org/10.1182/blood-2024-194593
Published: 2024
Journal Articles

Flow MRD Monitoring Combining Laip/Dfn and CD34+CD38- LSCs Is a Strong Predictor of Outcome in Adult AML Independently of the ELN-2022 Risk: First Results from the Multicentric Acute Leukemia French Intergroup MRD Flow Network

Adriana Plesa, Stéphanie Mathis, Florent Dumezy, Anne-Catherine Lhoumeau, Veronique Saada, Isabelle Arnoux, Jennifer Osman, Nicolas Chapuis, Franck Geneviève, Mikael Roussel, Delphine Manzoni, Anne Roggy, Remi Letestu, Veronique Harrivel, Elsa Bera, Jean Feuillard, Hélène Lapillonne, Richard Veyrat-Masson, Tatiana Raskovalova, Bouchra Badaoui, Valerie Bardet, Caroline Mayeur-Rousse, Francois Vergez, Jean Philippe Vial, Valerie Goncalves Monteiro, Frédéric Feger, Dominique Penther, Isabelle Luquet, Eric Delabesse, Nicolas Duployez, Karine Celli-Lebras, Mathilde Hunault, Raphael Itzykson, Arnaud Pigneux, Christian Récher, Hervé Dombret, Claude Preudhomme, Christophe Roumier
Journal: Blood
Blood (2024) 144 (Supplement 1): 226.
https://doi.org/10.1182/blood-2024-205457
Published: 2024
Journal Articles

Preemptive Therapy with Venetoclax for High-Risk Stage a CLL Patients: First Analysis of Prevene, a Phase II Trial of the Filo Group

Luc-Matthieu Fornecker, Rémi Letestu, Nanthara Shritaran, Emmanuelle Ferrant, Fressia Honeyman, Therese Aurran-Schleinitz, Fatiha Merabet, Pierre Morel, Abderrazak El Yamani, Jehan Dupuis, Kamel Laribi, Stephane Lepretre, Lysiane Molina, Hugo Legendre, Chadi Al Nawakil, Bruno Villemagne, Anne-Sophie Michallet, Béatrice Mahé, Omar Benbrahim, Laurence Sanhes, Caroline Dartigeas, Aline Clavert, Vincent Levy
Journal: Blood
Blood (2024) 144 (Supplement 1): 3256.
https://doi.org/10.1182/blood-2024-203081
Published: 2024
Journal Articles

Minimal Residual Disease-Guided Combination of Ibrutinib and Venetoclax Compared to FCR in Untreated Patients with CLL of Intermediate Risk : Interim Results of MRD Kinetics in the Eradic Trial from the Filo Group

Anne-Sophie Michallet, Anne Quinquenel, Remi Letestu, Tavernier Magali, Stéphane Morisset, Therese Aurran, Kamel Laribi, Florence Cymbalista, Vincent Levy, Laurence Simon, Damien Roos Weil, Veronique Leblond, Marie Sarah Dilhuydy, Cecile Tomowiak, Caroline Dartigeas, Romain Guieze, Olivier Tournilhac, Emmanuelle Ferrant, Sophie De Guibert, Pierre Feugier, Fatiha Merabet, Stéphane Lepretre, Philippe Carassou, Julie Gay, Benedicte Hivert, Luc Matthieu Fornecker, Jehan Dupuis, Lysiane Molina, Bruno Villemagne, Guillaume Cartron, Bernard Drenou, Béatrice Mahé, Omar Benbrahim, Xavier Cahu, Christelle Portois, Loic Ysebaert, Florence Nguyen Khac, Valerie Rouillé, Alain Jacques Delmer
Journal: Blood
Blood (2023) 142 (Supplement 1): 3268.
https://doi.org/10.1182/blood-2023-173341
Published: 2023
Journal Articles

Lenalidomide Consolidation Improves Measurable Residual Disease (MRD) Rates and Progression Free Survival in Patients with Chronic Lymphocytic Leukemia Following Initial FCR Chemotherapy - Final Analysis of CLL6 Residuum Study of the Australian Leukaemia and Lymphoma Group (ALLG) and the French Innovative Leukemia Organization (FILO)

Therese Aurran-Schleinitz, Stephen P Mulligan, Remi Letestu, Marie Christine Bene, Gavin Cull, Jean Pierre Vilque, Constantine S. Tam, Sophie De Guibert, Rosemary Anne Harrup, Bernard Drenou, Andrew P Grigg, Laurent Voillat, Belinda E Butcher, Caroline Dartigeas, Richard Eek, Nicolas Daguindau, Cecily Forsyth, Mourad Tiab, Delaine Smith, Jennifer Curnow, Veronique Leblond, Stephen Robert Larsen, Florence Cymbalista, David Gottlieb
Journal: Blood
Blood (2023) 142 (Supplement 1): 4641.
https://doi.org/10.1182/blood-2023-181595
Published: 2023
Journal Articles

AML MRD By Multiparameter Flow Cytometry Using Laip/Dfn and LSC: Methodological Aspects in a Multicentric Study of the French-Flow MRD AML ALFA Network

Adriana Plesa, Florent Dumezy, Stéphanie Mathis, Anne-Catherine Lhoumeau, Valerie Bardet, Véronique Saada, Isabelle Arnoux, Bouchra Badaoui, Edouard Cornet, Jennifer Osman, Estelle Guerin, Nicolas Chapuis, Franck Genevieve, Rémi Letestu, Delphine Manzoni, Anne Roggy, Mikael Roussel, Véronique Harrivel, Elsa Bera, Caroline Mayeur-Rousse, Hélène Lapillonne, Richard Veyrat-Masson, Lydia Campos, Magali Le Garff-Tavernier, Tatiana Raskovalova, Francois Vergez, Julien Guy, Agnes Charpentier, Claire Hemar, Valerie Goncalves Monteiro, Frederic Fegier, Karine Celli-Lebras, Raphael Itzykson, Herve Dombret, Claude Preudhomme, Christophe Roumier
Journal: Blood
Blood (2022) 140 (Supplement 1): 6279–6281.
https://doi.org/10.1182/blood-2022-169696
Published: 2022
Journal Articles

A Fixed-Duration Immunochemotherapy Approach Combined with Ibrutinib in CLL Produces Deep and Sustained MRD Responses: 5.5-Year Results from the Icll-07 Filo Trial

Anne-Sophie Michallet, Rémi Letestu, Magali Le Garff-Tavernier, Carmen Aanaei, Michel Ticchioni, Marie-Sarah Dilhuydy, Stephane Morisset, Valérie Rouille, Béatrice Mahé, Kamel Laribi, Bruno Villemagne, Emmanuelle Ferrant, Olivier Tournilhac, Alain Delmer, Christelle Portois, Lysiane Molina, Véronique Leblond, Cécile Tomowiak, Sophie de Guibert, Frederique Orsini, Anne Banos, Philippe Carassou, Guillaume Cartron, Luc Mathieu Fornecker, Loic Ysebaert, Caroline Dartigeas, Margot Truchan, Jean-Pierre Vilque, Therese Aurran Schleinitz, Cymbalista Florence, Stéphane Leprêtre, Vincent Lévy, Florence Nguyen Khac, Pierre Feugier
Journal: Blood
Blood (2022) 140 (Supplement 1): 7013–7015.
https://doi.org/10.1182/blood-2022-157963
Published: 2022
Journal Articles

Preliminary Results of the Filo Phase 2 Trial for Untreated Fit Patients with Intermediate Risk Chronic Lymphocytic Leukemia Comparing Ibrutinib Plus Venetoclax (IV) Versus FCR: Results of the Month 15 MRD Evaluation

Anne Quinquenel, Rémi Letestu, Magali Le Garff-Tavernier, Fabien Subtil, Therese Aurran-Schleinitz, Kamel Laribi, Florence Cymbalista, Vincent Levy, Laurence Simon, Damien Roos-Weil, Véronique Leblond, Marie-Sarah Dilhuydy, Caroline Dartigeas, Cecile Tomowiak, Romain Guieze, Olivier Tournilhac, Emmanuelle Ferrant, Sophie de Guibert, Pierre Feugier, Fatiha Merabet, Stephane Lepretre, Philippe Carassou, Julie Gay, Bénédicte Hivert, Luc Mathieu Fornecker, Jehan Dupuis, Lysiane Molina, Bruno Villemagne, Guillaume Cartron, Bernard Drenou, Béatrice Mahé, Omar Benbrahim, Xavier Cahu, Christelle Portois, Loic Ysebaert, Florence Nguyen Khac, Valérie Rouille, Alain Delmer, Anne-Sophie Michallet
Journal: Blood
Blood (2022) 140 (Supplement 1): 7007–7009.
https://doi.org/10.1182/blood-2022-159678
Published: 2022
Journal Articles

Characterisation of a New Clinical Presentation of Chronic Lymphocytic Leukemia with Symptomatic Nasopharyngeal Mucosa Involvement

Thimali Ranaweera Arachchige, Antoine Diep, Ambroise David, Melchior Le Mene, Virginie Eclache, Rémi Letestu, Xavier Troussard, Antoine Martin, Catherine Mendiburu, Fanny Baran-Marszak, Florence Cymbalista, Gregory Lazarian
Journal: Blood
Blood (2021) 138 (Supplement 1): 3741.
https://doi.org/10.1182/blood-2021-144958
Published: 2021
Journal Articles

Humoral Response to mRNA Vaccines BNT162b2 and mRNA-1273 COVID-19 in Chronic Lymphocytic Leukemia Patients

Cristina Bagacean, Rémi Letestu, Chadi Al Nawakil, Ségolène Brichler, Vincent Lévy, Nanthara Sritharan, Alain Delmer, Caroline Dartigeas, Véronique Leblond, Damien Roos-Weil, Marie C Béné, Aline Clavert, Driss Chaoui, Philippe Genet, Romain Guieze, Kamel Laribi, Yamina Touileb, Bernard Drenou, Lise Willems, Cécile Tomowiak, Fatiha Merabet, Christian Puppink, Hugo Legendre, Xavier Troussard, Stéphanie Malartre, Florence Cymbalista, Anne-Sophie Michallet
Journal: Blood
Blood (2021) 138 (Supplement 1): 637.
https://doi.org/10.1182/blood-2021-152515
Published: 2021
Journal Articles

Preliminary Results of the Filo Phase 2 Trial for Untreated Fit Patients with Intermediate Risk Chronic Lymphocytic Leukemia Comparing Ibrutinib Plus Venetoclax (IV) Versus FCR

Anne-Sophie Michallet, Anne Quinquenel, Remi Letestu, Magali Le Garff-Tavernier, Fabien Subtil, Mad-Helenie Elsensohn, Therese Aurran, Kamel Laribi, Florence Cymbalista, Vincent Levy, Laurence Simon, Damien Roos-Weil, Veronique Leblond, Marie-Sarah Dilhuydy, Cécile Tomowiak, Caroline Dartigeas, Romain Guieze, Olivier Tournilhac, Emmanuelle Ferrant, Sophie de Guibert, Pierre Feugier, Fatiha Merabet, Stéphane Leprêtre, Philippe Carassou, Julie Gay, Bénédicte Hivert, Luc Mathieu Fornecker, Jehan Dupuis, Lysiane Molina, Bruno Villemagne, Guillaume Cartron, Bernard Drenou, Béatrice Mahé, Omar Benbrahim, Xavier Cahu, Christelle Portois, Loic Ysebaert, Florence Nguyen-Khac, Valérie Rouille, Alain Delmer
Journal: Blood
Blood (2021) 138 (Supplement 1): 641.
https://doi.org/10.1182/blood-2021-145624
Published: 2021
Journal Articles

A fixed-duration, measurable residual disease–guided approach in CLL: follow-up data from the phase 2 ICLL-07 FILO trial

Clinical Trials & Observations Brief Report
Anne-Sophie Michallet, Rémi Letestu, Magali Le Garff-Tavernier, Carmen Aanei, Michel Ticchioni, Marie-Sarah Dilhuydy, Fabien Subtil, Valerie Rouille, Beatrice Mahe, Kamel Laribi, Bruno Villemagne, Gilles Salles, Olivier Tournilhac, Alain Delmer, Christelle Portois, Brigitte Pegourie, Veronique Leblond, Cecile Tomowiak, Sophie De Guibert, Frederique Orsini Piocelle, Anne Banos, Philippe Carassou, Guillaume Cartron, Luc-Matthieu Fornecker, Loic Ysebaert, Caroline Dartigeas, Malgorzata Truchan-Graczyk, Jean-Pierre Vilque, Thérèse Aurran, Florence Cymbalista, Stéphane Lepretre, Vincent Levy, Florence Nguyen-Khac, Pierre Feugier
Journal: Blood
Blood (2021) 137 (8): 1019–1023.
https://doi.org/10.1182/blood.2020008164
Published: 2021
Includes: Supplemental data
Journal Articles

The Broad Spectrum of TP53 Variants in CLL: NGS Analysis of 573 Pathogenic TP53 Variants

Gregory Lazarian, PharmD, Floriane Theves, Myriam Hormi, Virginie Eclache, Stéphanie Poulain, MD, Audrey Bidet, Cedric Pastoret, MD, Lauren Veronese, MD PhD, Eric Delabesse, MD PhD, Marie-Hélène Estienne, Nathalie Nadal, Frederic Davi, MD PhD, Florence Nguyen-Khac, MD PhD, Laurence Lode, Pierre Sujobert, MD PhD, Dina Naguib, MD, Sophie Raynaud, Stephane Giraudier, MD PhD, Olivier Kosmider, PharmD, PhD, Pascaline Etancelin, Pascale Cornillet-Lefebvre, Laurent Miguet, DPhil, Veronique Leblond, MD PhD, Remi Letestu, Thierry Soussi, Florence Cymbalista, MD PhD, Fanny Baran-Marszak, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3021.
https://doi.org/10.1182/blood-2019-130907
Published: 2019
Journal Articles

Maintenance of Long-Term Undetectable Minimal Residual Disease after Combination of Ibrutinib with Abbreviated Chemotherapy in the Icll-07 Filo Trial

Anne-Sophie Michallet, MD PhD, Marie-Sarah Dilhuydy, MD, Fabien Subtil, Valérie Rouille, Beatrice Mahe, MD, Kamel Laribi, MD, Bruno Villemagne, MD, Gilles A. Salles, MD PhD, Olivier Tournilhac, Alain Jacques Delmer, MD PhD, Christelle Portois, Brigitte Pegourie, MD, Veronique Leblond, MD PhD, Cecile Tomowiak, MD, Sophie de Guibert, MD, Frederique Orsini, Anne Banos, MD, Philippe Carassou, Guillaume Cartron, Luc Mathieu Fornecker, MD PhD, Loic Ysebaert, MD PhD, Caroline Dartigeas, MD, Margot Truchan, Jean Pierre Vilque, Thérèse Aurran, MD, Florence Cymbalista, MD PhD, Stephane Lepretre, Vincent Levy, MD PhD, Florence Nguyen-Khac, MD PhD, Magali Le Garff-Tavernier, Carmen Aanaei, Michel Ticchioni, Remi Letestu, Pierre Feugier, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3038.
https://doi.org/10.1182/blood-2019-126720
Published: 2019
Journal Articles

Prevalence of BTK and PLCG2 mutations in a real-life CLL cohort still on ibrutinib after 3 years: a FILO group study

Brief Report
Anne Quinquenel, Luc-Matthieu Fornecker, Rémi Letestu, Loïc Ysebaert, Carole Fleury, Grégory Lazarian, Marie-Sarah Dilhuydy, Delphine Nollet, Romain Guieze, Pierre Feugier, Damien Roos-Weil, Lise Willems, Anne-Sophie Michallet, Alain Delmer, Katia Hormigos, Vincent Levy, Florence Cymbalista, Fanny Baran-Marszak
Journal: Blood
Blood (2019) 134 (7): 641–644.
https://doi.org/10.1182/blood.2019000854
Published: 2019
Includes: Supplemental data
Journal Articles

High Prevalence of BTK Mutations on Ibrutinib Therapy after 3 Years of Treatment in a Real-Life Cohort of CLL Patients: A Study from the French Innovative Leukemia Organization (FILO) Group

Anne Quinquenel, Luc Matthieu Fornecker, Remi Letestu, Carole Fleury, Loic Ysebaert, MD PhD, Marie-Sarah Dilhuydy, MD, Romain Guieze, MD, Pierre Feugier, Damien Roos-Weil, MD, Lise Willems, MD, Anne-Sophie Michallet, MD PhD, Alain Jacques Delmer, MD, Pietro Taverna, PhD, Judith A. Fox, PhD, Vincent Levy, MD PhD, Florence Cymbalista, MD, Fanny Baran-Marszak, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 584.
https://doi.org/10.1182/blood-2018-99-114027
Published: 2018
Journal Articles

High Rate of Complete Response (CR) with Undetectable Bone Marrow Minimal Residual Disease (MRD) after Chemo-Sparing and MRD-Driven Strategy for Untreated Fit CLL Patients: Final Results of the Icll 07 Filo Trial

Anne-Sophie Michallet, MD PhD, Marie-Sarah Dilhuydy, MD, Fabien Subtil, Valérie Rouille, Beatrice Mahe, MD, Kamel Laribi, MD, Bruno Villemagne, Gilles Andre Salles, MD PhD, Olivier Tournilhac, MD PhD, Alain Jacques Delmer, MD, Christelle Portois, Brigitte Pegourie, MD, Véronique Leblond, MD PhD, Cecile Tomowiak, MD, Sophie de Guibert, MD, Frederique Orsini, Anne Banos, MD, Philippe Carassou, Guillaume Cartron, Luc Mathieu Fornecker, Loic Ysebaert, MD PhD, Caroline Dartigeas, Margot Truchan, Thérèse Aurran, MD, Florence Cymbalista, MD, Stéphane Leprêtre, MD, Vincent Levy, MD PhD, Florence Nguyen-Khac, MD PhD, Magali Le Garff-Tavernier, Carmen Aanaei, Michel Ticchioni, Remi Letestu, Pierre Feugier
Journal: Blood
Blood (2018) 132 (Supplement 1): 1858.
https://doi.org/10.1182/blood-2018-99-111977
Published: 2018
Journal Articles

First Interim Analysis of the French National Observatory of Paroxysmal Nocturnal Hemoglobinuria Clones

Magali Le Garff-Tavernier, Bernard Drenou, MD, Agathe Pruvot Debliquis, Remi Letestu, Bernard Chatelain, PhD BPharm, Thomas Boyer, Jean-Philippe Vial, MD, Michael Peres, MD, Véronique Harrivel, MD, Gérard Socié, MDPhD, Regis Peffault De Latour, MD PhD, Orianne Wagner Ballon
Journal: Blood
Blood (2017) 130 (Supplement 1): 4960.
https://doi.org/10.1182/blood.V130.Suppl_1.4960.4960
Published: 2017
Journal Articles

Phase II, Multicenter Trial, Exploring "Chemo-Sparing" Strategy Associating Obinutuzumab+Ibrutinib Followed By a MRD Driven Strategy, in Previously Untreated Symptomatic Medically Fit Chronic Lymphocytic Leukemia Patients (CLL): Preliminary Results of the Induction Phase of the Icll-07 Filo Study

Anne-Sophie Michallet, MD PhD, Marie-Sarah Dilhuydy, MD, Fabien Subtil, Valérie Rouille, Beatrice Mahe, MD, Kamel Laribi, Bruno Villemagne, Gilles Andre Salles, MD PhD, Olivier Tournilhac, MD PhD, Alain Jacques Delmer, MD, Christelle Portois, Brigitte Pegourie, MD, Veronique Leblond, Cecile Tomowiak, MD, Sophie de Guibert, Frederique Orsini, Anne Banos, MD, Philippe Carassou, Guillaume Cartron, Luc Mathieu Fornecker, Loic Ysebaert, MD PhD, Caroline Dartigeas, Margot Truchan, Thérèse Aurran, MD, Florence Cymbalista, MD, Stéphane Leprêtre, MD, Vincent Levy, MD PhD, Florence Nguyen Khac, Magali Le Garff-Tavernier, Carmen Aanaei, Michel Ticchioni, Remi Letestu, Pierre Feugier, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 497.
https://doi.org/10.1182/blood.V130.Suppl_1.497.497
Published: 2017