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Christian Michel Zwaan
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Journal Articles

Characterizing the Bone Marrow Stromal Niche in Pediatric Acute Myeloid Leukemia

Elizabeth K Schweighart, Cristoforo Grasso, Brigit M. te Pas, Mirjam E. Belderbos, Christian Michel Zwaan, Hendrik G. Stunnenberg, Olaf Heidenreich, Bianca F. Goemans
Journal: Blood
Blood (2024) 144 (Supplement 1): 4062.
https://doi.org/10.1182/blood-2024-204988
Published: 2024
Journal Articles

WU-CART-007 (WT-7), an Allogeneic CAR T-Cell Targeting CD7 in Relapsed/Refractory (R/R) T-Cell Acute Lymphoblastic Leukemia/Lymphoma (T-ALL/LBL): Phase 2 Results

Armin Ghobadi, Ibrahim Aldoss, Shannon L. Maude, Deepa Bhojwani, Rawan Faramand, Ashish Bajel, Friso G. J. Calkoen, Alan S. Wayne, Bhagirathbhai Dholaria, Ryan J Mattison, Anita W. Rijneveld, Christian Michel Zwaan, André Baruchel, Nicolas Boissel, Michael P. Rettig, Maria del Rosario, Stephen Moran, Alexander Hamil, Ouiam Bakkacha, Deborah Masters, Justo L. Gonzalez, Michael Munroe, Laura Simpson, Preeta Dasgupta, Tony Wu, John Muth, Haley Irons, Brett Ramsey, Eileen McNulty, Matthew L. Cooper, Jan K Davidson-Moncada, John F. DiPersio
Journal: Blood
Blood (2024) 144 (Supplement 1): 3450.
https://doi.org/10.1182/blood-2024-202005
Published: 2024
Journal Articles

WUC007-03: A Phase 2 Study of Anti-CD7 Allogenic CAR-T Cells (WT-7) in Patients with Relapsed/Refractory (R/R) T-Cell Acute Lymphoblastic Leukemia (T-ALL)/Lymphoblastic Lymphoma (LBL)

Armin Ghobadi, Shannon L. Maude, Ibrahim Aldoss, Ashish Bajel, Ryan J Mattison, Deepa Bhojwani, Alan S. Wayne, Rawan Faramand, Bhagirathbhai Dholaria, Seong Lin Khaw, Anita W. Rijneveld, Friso G. J. Calkoen, Christian Michel Zwaan, André Baruchel, Nicolas Boissel, Andrej Lissat, Stefan Schwartz, Peter Bader, Fabian Lang, Michael P. Rettig, Haley Irons, Brett Ramsey, John Muth, Laura Simpson, Preeta Dasgupta, Stephen Moran, Michael Munroe, Maria del Rosario, Tony Wu, Ouiam Bakkacha, Justo L. Gonzalez, Deborah Masters, Alexander Hamil, Eileen McNulty, Matthew L. Cooper, Jan K Davidson-Moncada, John F. DiPersio
Journal: Blood
Blood (2024) 144 (Supplement 1): 7225.
https://doi.org/10.1182/blood-2024-201825
Published: 2024
Journal Articles

The Interplay between Macrophages and Pediatric AML Blasts

Alicia Perzolli, Joost B. Koedijk, Elizabeth K Schweighart, Bianca F. Goemans, Christian Michel Zwaan, Olaf Heidenreich
Journal: Blood
Blood (2024) 144 (Supplement 1): 5653.
https://doi.org/10.1182/blood-2024-204948
Published: 2024
Journal Articles

WU-CART-007 (WT-7) Is an Effective Treatment for Adolescent Patients with Relapsed or Refractory (R/R) T-Cell Acute Lymphoblastic Leukemia/ Lymphoblastic Lymphoma (T-ALL/LBL) - Subgroup Analysis of WU-CART-007 1001

Shannon L. Maude, Deepa Bhojwani, Alan S. Wayne, Friso G. J. Calkoen, André Baruchel, Christian Michel Zwaan, Michael P. Rettig, Ouiam Bakkacha, Justo L. Gonzalez, Deborah Masters, Maria del Rosario, Laura Simpson, Preeta Dasgupta, Tony Wu, Stephen Moran, Michael Munroe, Haley Irons, Eileen McNulty, Matthew L. Cooper, Alexander Hamil, John Muth, Brett Ramsey, Jan K Davidson-Moncada, John F. DiPersio
Journal: Blood
Blood (2024) 144 (Supplement 1): 3461.
https://doi.org/10.1182/blood-2024-201998
Published: 2024
Journal Articles

Immunotherapy: genetically agnostic in BCP-ALL?

Christian Michel Zwaan, Friso G. J. Calkoen
Journal: Blood
Blood (2022) 139 (14): 2093–2094.
https://doi.org/10.1182/blood.2022015618
Published: 2022
Journal Articles

A phase 1 study of inotuzumab ozogamicin in pediatric relapsed/refractory acute lymphoblastic leukemia (ITCC-059 study)

Clinical Trials & Observations
Erica Brivio, Franco Locatelli, Marta Lopez-Yurda, Andrea Malone, Cristina Díaz-de-Heredia, Bella Bielorai, Claudia Rossig, Vincent H. J. van der Velden, Anneke C. J. Ammerlaan, Adriana Thano, Inge M. van der Sluis, Monique L. den Boer, Ying Chen, Barbara Sleight, Benoit Brethon, Karsten Nysom, Lucie Sramkova, Ingrid Øra, Luciana Vinti, Christiane Chen-Santel, Christian Michel Zwaan
Journal: Blood
Blood (2021) 137 (12): 1582–1590.
https://doi.org/10.1182/blood.2020007848
Published: 2021
Includes: Supplemental data
Journal Articles

A Phase II Study of Single-Agent Inotuzumab Ozogamicin in Pediatric CD22-Positive Relapsed/Refractory Acute Lymphoblastic Leukemia: Results of the ITCC-059 Study

Erica Brivio, MD, Franco Locatelli, MD, Adriana Thano, Arnaud Petit, MD PhD, Britta Julia Vormoor, MD, Susana Rives, Bella Bielorai, MD, Claudia Rossig, Carmelo Rizzari, Vincent H.J. Van Der Velden, PhD, Anneke C.J. Ammerlaan, Monique L. Den Boer, PhD, Barbara Sleight, MD, Gernot Engstler, Jan Stary, MD PhD, Francisco José Bautista Sirvent, MD PhD, Christiane Chen-Santel, Bénédicte Bruno, MD, Yves Bertrand, MD, Fanny Rialland, MD, Geneviève Plat, Dirk Reinhardt, MD, Luciana Vinti, MD, Arend von Stackelberg, MD, Christian Michel Zwaan
Journal: Blood
Blood (2020) 136 (Supplement 1): 8–9.
https://doi.org/10.1182/blood-2020-134774
Published: 2020
Journal Articles

Phase 2 study of nilotinib in pediatric patients with Philadelphia chromosome–positive chronic myeloid leukemia

Clinical Trials & Observations
Nobuko Hijiya, Alexey Maschan, Carmelo Rizzari, Hiroyuki Shimada, Carlo Dufour, Hiroaki Goto, Hyoung Jin Kang, Terri Guinipero, Zeynep Karakas, Francisco Bautista, Stéphane Ducassou, Keon Hee Yoo, Christian Michel Zwaan, Frédéric Millot, Paola Aimone, Alex Allepuz, Sara Quenet, Florence Hourcade-Potelleret, Sabine Hertle, Darintr Sosothikul
Journal: Blood
Blood (2019) 134 (23): 2036–2045.
https://doi.org/10.1182/blood.2019000069
Published: 2019
Includes: Supplemental data
Journal Articles

A Retrospective Study on Inotuzumab Ozogamicin in Infants and Young Children with Relapsed or Refractory Acute Lymphoblastic Leukemia (ALL)

Erica Brivio, MD, Raoull Hoogendijk, MSc, Christophe Chantrain, MD PhD, Fanny Rialland, MD, Audrey Contet, Sarah Elitzur, MD, Luciano Dalla-Pozza, MBBS FRACP, Krisztian Kallay, MD, Chi Kong Li, MBBS,MD, Motohiro Kato, MD PhD, Inna V Markova, Dr., Kjeld Schmiegelow, Professor MD DMSc., Nicole Bodmer, Rob Pieters, MDPhDMSc, Christian Michel Zwaan, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3890.
https://doi.org/10.1182/blood-2019-126472
Published: 2019
Journal Articles

Phase II Study of Midostaurin + Chemotherapy in Pediatric Patients with Untreated, Newly Diagnosed, FLT3 -Mutated Acute Myeloid Leukemia (AML)

Dirk Reinhardt, MD, Christian Michel Zwaan, Albert Hoenekopp, Julie Niolat, Sophie Ifrah, Florence Noel-Baron, Franco Locatelli, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3835.
https://doi.org/10.1182/blood-2019-128043
Published: 2019
Journal Articles

Safety, Efficacy, and PK of the BCL2 Inhibitor Venetoclax in Combination with Chemotherapy in Pediatric and Young Adult Patients with Relapsed/Refractory Acute Myeloid Leukemia and Acute Lymphoblastic Leukemia: Phase 1 Study

Seth E Karol, MD, Todd M Cooper, DO, Henrique Bittencourt, Lia Gore, MD, Maureen M O'Brien, MD, Christopher Fraser, MD, Marion Gambart, MD, Gunnar Cario, MD PhD, Christian Michel Zwaan, MD PhD, Jean-Pierre Bourquin, MD PhD, Mignon L. Loh, MD, Hubert Caron, MD PhD, Betty Prine, Ahmed Hamed Salem, PhD FCP, Kristina Unnebrink, Bo Tong, PhD, Tammy Palenski, PhD, Andrew E. Place, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2649.
https://doi.org/10.1182/blood-2019-129805
Published: 2019
Journal Articles

A Phase I Study of Single-Agent Inotuzumab Ozogamicin in Pediatric CD22-Positive Relapsed/Refractory Acute Lymphoblastic Leukemia: Preliminary Results of the ITCC-059 Study

Erica Brivio, MD, Marta Lopez-Yurda, PhD, Cormac Ownes, MD, Cristina Díaz de Heredia, MD PhD, Bella Bielorai, MD, Claudia Rossig, Vincent van der Velden, PhD, Anneke C.J. Ammerlaan, Inge M. van der Sluis, MD PhD, Monique L. Den Boer, PhD, Ying Chen, Barbara Sleight, MD, Benoit Brethon, MD, Karsten Nysom, Jan Stary, Prof., MD PhD, Ingrid Øra, Christiane Chen-Santel, Luciana Vinti, MD, Franco Locatelli, MD PhD, Christian Michel Zwaan, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2629.
https://doi.org/10.1182/blood-2019-122411
Published: 2019
Journal Articles

Integrative Analysis of Pediatric Acute Leukemia Identifies Immature Subtypes That Span a T Lineage and Myeloid Continuum with Distinct Prognoses

Tanja A. Gruber, MD PhD, Jing Ma, PhD, Sanne Noort, MD MSc, Yu Liu, PhD, Michael P Walsh, PhD, Stephanie Nance, PhD, Yanling Liu, PhD, Yuanyuan Wang, PhD, Guangchun Song, PhD, Tamara Lamprecht, BS, John Easton, PhD, Martina Pigazzi, PhD, Marie Jarosova, PhD, Kelaidi Charikleia, MD, Jeffrey Rubnitz, MD PhD, Dirk Reinhardt, MD, Marry M. van den Heuvel-Eibrink, Prof, MD PhD, Franco Locatelli, MD PhD, Henrik Hasle, Jeffery M. Klco, MD PhD, James R. Downing, MD, Stanley Pounds, PhD, Jinghui Zhang, PhD, Christian Michel Zwaan, MD PhD, Maarten Fornerod, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 918.
https://doi.org/10.1182/blood-2019-127411
Published: 2019
Journal Articles

CEBPA resembles Roman god Janus

Iris H. I. M. Hollink, Marry M. van den Heuvel-Eibrink, Christian Michel Zwaan
Journal: Blood
Blood (2009) 113 (26): 6501–6502.
https://doi.org/10.1182/blood-2009-04-214296
Published: 2009
Journal Articles

Does modulation of P-glycoprotein have clinical relevance in pediatric acute myeloid leukemia?

Christian Michel Zwaan, Monique L. den Boer, Karin M. Kazemier, Karel Hählen, Anne H. Loonen, Dirk Reinhardt, Ursula Creutzig, Gertjan J. L. Kaspers, Rob Pieters
Journal: Blood
Blood (2006) 107 (12): 4975–4977.
https://doi.org/10.1182/blood-2006-01-0309
Published: 2006