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Curtis J Henry
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Journal Articles

Obesity Attenuates CAR T-Cell Function in Pediatric B-Cell Acute Lymphoblastic Leukemia

Jessica Maaskant, Anthony J Ross, Karmella A Haynes, Alysa N Evans, Emily C Sullivan, Elizabeth P Weinzerl, Heather Lin, Dejah Blake, Liora Michal Schultz, Sunil S Raikar, Sarwish Rafiq, Curtis J Henry
Journal: Blood
Blood (2024) 144 (Supplement 1): 4807.
https://doi.org/10.1182/blood-2024-212050
Published: 2024
Journal Articles

Early B-cell development and B-cell maturation are impaired in patients with active hemophagocytic lymphohistiocytosis

Jenny Shim, Sunita Park, Suresh Venkateswaran, Deepak Kumar, Chengyu Prince, Vaunita Parihar, Larkin Maples, Edmund K. Waller, Subra Kugathasan, Michael Briones, Miyoung Lee, Curtis J. Henry, Sampath Prahalad, Shanmuganathan Chandrakasan
Journal: Blood
Blood (2023) 142 (23): 1972–1984.
https://doi.org/10.1182/blood.2023020426
Published: 2023
Includes: Supplemental data
Journal Articles

Obesity Associates with Inferior Outcomes and Toxicity in Pediatric and Young Adult Patient with Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia Treated with Commercially Manufactured Tisagenlecleucel

Anthony J Ross, Christina Baggott, Snehit Prabhu, Holly Pacenta, Christine Philips, Jenna Rossoff, Heather E Stefanski, Julie Talano, Amy Moskop, Susanne H.C. Baumeister, Michael R Verneris, Gary Douglas Myers, Nicole Karras, Muna Qayed, Michelle L. Hermiston, Prakash Satwani, Christa Krupski, Amy K. Keating, Rachel Wilcox, Vanessa A Fabrizio, Vasant Chinnabhandar, Kevin J. Curran, Crystal L. Mackall, Theodore W. Laetsch, Sandra K Althouse, Shannon L. Maude, Curtis J Henry, Liora M. Schultz, Jodi L. Skiles
Journal: Blood
Blood (2022) 140 (Supplement 1): 10419–10421.
https://doi.org/10.1182/blood-2022-163336
Published: 2022
Journal Articles

Lyt-200, a Humanized Anti-Galectin-9 Antibody, Exhibits Preclinical Efficacy in Models of Hematological Malignancies

Curtis J Henry, Miyoung Lee, Aleksandra Filipovic
Journal: Blood
Blood (2022) 140 (Supplement 1): 8837.
https://doi.org/10.1182/blood-2022-169811
Published: 2022
Journal Articles

Combinatorial Inhibition of Galectin-9 and CHK1 Represent a Novel Treatment Strategy for T-Cell Acute Lymphoblastic Leukemia

Miyoung Lee, Aleksandra Filipovic, Curtis J Henry
Journal: Blood
Blood (2021) 138 (Supplement 1): 4400.
https://doi.org/10.1182/blood-2021-154404
Published: 2021
Journal Articles

Interleukin-9 Promotes Chemoresistance in B-ALL Which Correlates with Decreased Bim and c-Raf Protein Expression

Jamie A.G. Hamilton, Miyoung Lee, Claire E. Pillsbury, Curtis J Henry
Journal: Blood
Blood (2021) 138 (Supplement 1): 2386.
https://doi.org/10.1182/blood-2021-153010
Published: 2021
Journal Articles

Single Cell Transcriptomics Revealed AML and Non-AML Cell Clusters Relevant to Relapse and Remission in Pediatric AML

Beena E Thomas, Pruthvi Perumalla, MS, Swati S Bhasin, PhD, Debasree Sarkar, PhD, Bhakti Dwivedi, PhD, Sunita I Park, MD, Deborah DeRyckere, BS,PhD, Curtis J. Henry, PhD, Sunil S. Raikar, MD, Christopher C. Porter, MD, Melinda Pauly, MD, Ryan J Summers, MD, Sharon M. Castellino, MD MSc, Daniel S. Wechsler, MD PhD, Douglas K Graham, MD PhD, Manoj Bhasin, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 24–25.
https://doi.org/10.1182/blood-2020-142513
Published: 2020
Journal Articles

Obesity Attenuates T-Cell Function Which Impacts the Efficacy of T-Cell Based Immunotherapies in Acute Lymphoblastic Leukemia

Anthony Ross, MD, Miyoung Lee, PhD, Jamie Hamilton, Raira Ank, Priscilla Do, PhD, Jamie Story, Sunil S. Raikar, MD, Erik Dreaden, PhD, Christopher C. Porter, MD, Curtis J. Henry, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 25–26.
https://doi.org/10.1182/blood-2020-136573
Published: 2020
Journal Articles

Obesity-Induced Chemoresistance in B-Cell Acute Lymphoblastic Leukemia Cells Is Mediated By Reduced Chemotherapy Uptake and Interleukin-9 Signaling

Jamie A.G. Hamilton, BS, Miyoung Lee, PhD, Ganesh R Talekar, PhD, Curtis J. Henry, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 37–38.
https://doi.org/10.1182/blood-2020-143164
Published: 2020
Journal Articles

Elevated Levels of Interleukin-9 in Obese Microenvironments Promote Leukemia Progression and Chemoresistance in B-Cell Acute Lymphoblastic Leukemia Cells

Jamie A.G. Hamilton, BS, Miyoung Lee, PhD, Ganesh R Talekar, PhD, Curtis J. Henry, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1468.
https://doi.org/10.1182/blood-2019-126139
Published: 2019
Journal Articles

Mertk Inhibition Promotes Anti-Leukemia Immunity By Reversing T Cell Suppression Via the PD-1 Axis

Alisa Lee-Sherick, MD, Kristen Jacobsen, PhD, Curtis J. Henry, PhD, Rebecca Parker, Xiaodong Wang, PhD, Stephen V Frye, PhD, H. Shelton Earp, MD, Deborah DeRyckere, PhD, Douglas K Graham, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4019.
https://doi.org/10.1182/blood-2018-99-119818
Published: 2018
Journal Articles

Obesity-Induced Chronic Inflammation Suppresses the Function of Non-Malignant Immune Cells While Upregulating PD-L1 on Human B-ALL Cell Lines

Miyoung Lee, PhD, Curtis J. Henry, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1015.
https://doi.org/10.1182/blood.V130.Suppl_1.1015.1015
Published: 2017