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Journal Articles

Development of Humanized Antibodies Against Vasoactive Intestinal Polypeptide for Increased T Cell Anti-Leukemia Activity

Justin Adeyeye, Cynthia R. Giver, Jamie Cohen, Yuou Wang, Tysheena P. Charles, Khue G. Nguyen, Jian-Ming Li, Jens Wrammert, David A. Zaharoff, Edmund K. Waller

Blood (2024) 144 (Supplement 1): 4964.

https://doi.org/10.1182/blood-2024-203518

Published: 2024

Journal Articles

VIP Expression Drives an Immunosuppressive Tumor Microenvironment in TP53-Mutated AML

Fanyuan Zeng, Kiranj Chaudagar, Yuou Wang, Jian-Ming Li, Edmund K. Waller

Blood (2024) 144 (Supplement 1): 4299.

https://doi.org/10.1182/blood-2024-208170

Published: 2024

Journal Articles

Donor T Cell Infusions Limit Novel Immune Checkpoint Therapy in Pancreatic Cancer: Implications for Adoptive T Cell Therapy

Po-Chih Hsu, Edmund K. Waller, Tenzin Passang, Shuhua Wang, Jian-Ming Li

Blood (2023) 142 (Supplement 1): 2144.

https://doi.org/10.1182/blood-2023-190645

Published: 2023

Journal Articles

Indole-3-Carbinol Supplement Reduces GvHD Related Mortality in Allogeneic Hematopoietic Stem Cell Transplant Recipients

Pankoj Kumar Das, Saketh Kollipara, Alyson Swimm, Jian-Ming Li, Shuhua Wang, Saja K. Asakrah, David L Jaye, Cynthia R. Giver, Daniel Kalman, Edmund K. Waller

Blood (2022) 140 (Supplement 1): 4457–4458.

https://doi.org/10.1182/blood-2022-166698

Published: 2022

Journal Articles

High Potency Vasoactive Intestinal Peptide Receptor Antagonists Induce Durable Antileukemia/Tumor T Cell Memory in Mice with Once Daily Dosing

Jian-Ming LI, Tenzin Passang, Pankoj Kumar Das, Shuhua Wang, Anish Sen-Majumdar, Nikolaos Papadantoonakis, Cynthia R. Giver, Edmund K. Waller

Blood (2022) 140 (Supplement 1): 4955–4956.

https://doi.org/10.1182/blood-2022-170718

Published: 2022

Journal Articles

Donor plasmacytoid dendritic cells limit graft-versus-host disease through vasoactive intestinal polypeptide expression

Jingru Zhu, Yitong Wang, Jingxia Li, Pankoj Kumar Das, Hanwen Zhang, Tenzin Passang, Jian Ming Li, Tamas Nagy, Khanjan Gandhi, Sruthi Ravindranathan, Cynthia R. Giver, Mojibade Hassan, Yiwen Li, Alina Ulezko Antonova, Shuhua Wang, John D. Roback, Edmund K. Waller

Blood (2022) 140 (12): 1431–1447.

https://doi.org/10.1182/blood.2021012561

Published: 2022

Includes: Supplemental data

Journal Articles

Donor Plasmacytoid Dendritic Cells Regulate GvHD in a VIP Dependent Manner in Allogeneic BMT Recipients

Jingru Zhu, Pankoj Kumar Das, Yitong Wang, Jingxia Li, Tamas Nagy, Khajan Ghandhi, Sruthi Ravindranathan, Cynthia R. Giver, Jian-Ming Li, Yiwen Li, Alina Ulezko Antonova, John D Roback, Shuhua Wang, Edmund K. Waller

Blood (2021) 138 (Supplement 1): 1687.

https://doi.org/10.1182/blood-2021-152945

Published: 2021

Journal Articles

Presence of Vasoactive Intestinal Polypeptide Signaling in Plasmacytoid Dendritic Cells Improves Survival in a Murine Allo-BMT Model

Jing-Xia Li, Jian-Ming Li, PhD, Edmund K Waller, MD PhD

Blood (2016) 128 (22): 2154.

https://doi.org/10.1182/blood.V128.22.2154.2154

Published: 2016

Journal Articles

Absence of Vasoactive Intestinal Peptide Signaling Significantly Enhances T Cell Survival Following MCMV Infection Via Increased Expression of Bcl-2 and Bcl-XL

Christopher T Petersen, Graduate, Katarzyna Anna Darlak, PhD, Jian-Ming Li, PhD, Edmund K Waller, MD PhD

Blood (2015) 126 (23): 1028.

https://doi.org/10.1182/blood.V126.23.1028.1028

Published: 2015

Journal Articles

T Cell Activation By Plasmacytoid Dendritic Cells Is Augmented By Inhibition of Vasoactive Intestinal Polypeptide Signaling: Implications for Cellular Immunotherapy

Jingxia Li, Reema Panjwani, Jian-Ming Li, PhD, Cynthia R. Giver, PhD, Maryellen Malone, Edmund K Waller, MD PhD

Blood (2015) 126 (23): 3438.

https://doi.org/10.1182/blood.V126.23.3438.3438

Published: 2015

Journal Articles

Blocking VIP Signaling during Allogeneic Bone Marrow Transplantation Separates the Graft Versus Leukemia from Graft Versus Host Disease Activity of Donor CD8 T-Cells

Jian-Ming Li, PhD, Christopher T Petersen, Graduate, Jingxia Li, Graduate, Cynthia R. Giver, PhD, Bruce R. Blazar, MD, Edmund K Waller, MD PhD

Blood (2015) 126 (23): 1877.

https://doi.org/10.1182/blood.V126.23.1877.1877

Published: 2015

Journal Articles

VIP-Receptor Antagonist Enhanced Antileukemic Activity In Mice

Jian-Ming Li, Ph.D, Christopher Thomas Petersen, Graduate, Katarzyna Anna Darlak, Graduate, Hyun Don Yun, MD, Bruce R Blazar, MD, Edmund K. Waller, MD, PhD

Blood (2013) 122 (21): 1664.

https://doi.org/10.1182/blood.V122.21.1664.1664

Published: 2013

Journal Articles

Pharmacological inhibition of VIP signaling enhances antiviral immunity and improves survival in murine cytomegalovirus-infected allogeneic bone marrow transplant recipients

Jian-Ming Li, Mohammad S. Hossain, Lauren Southerland, Edmund K. Waller

Blood (2013) 121 (12): 2347–2351.

https://doi.org/10.1182/blood-2012-06-437640

Published: 2013

Includes: Supplemental data

Journal Articles

Blockade of VIP-Signaling Enhanced Anti-Leukemic Activity in Murine Allogeneic BMT without Significantly Increased GvHD.

Jian-Ming Li, PhD, Hyun Don Yun, Edmund K. Waller, MD, PhD

Blood (2012) 120 (21): 3001.

https://doi.org/10.1182/blood.V120.21.3001.3001

Published: 2012

Journal Articles

IFN-γ and indoleamine 2,3-dioxygenase signaling between donor dendritic cells and T cells regulates graft versus host and graft versus leukemia activity

Ying Lu, Cynthia R. Giver, Akshay Sharma, Jian Ming Li, Katarzyna A. Darlak, Lauren M. Owens, John D. Roback, Jacques Galipeau, Edmund K. Waller

Blood (2012) 119 (4): 1075–1085.

https://doi.org/10.1182/blood-2010-12-322891

Published: 2012

Journal Articles

Blocking Vasoactive Intestinal Peptide Signaling Enhances Anti-Viral Immunity without Increased Graft Versus Host Disease in Murine Allogeneic Bone Marrow Transplantation

Jian-Ming Li, Ph.D, Ying Wang, MD, Katarzyna Darlak, Graduate, Lauren T Southerland, MD, Mohammad S Hossain, Ph.D, Cynthia R. Giver, PhD, James A. Waschek, Edmund K Waller, MD PhD

Blood (2011) 118 (21): 1002.

https://doi.org/10.1182/blood.V118.21.1002.1002

Published: 2011

Journal Articles

Lack of Host Bone Marrow-Derived Interleukin-12 Increased the Incidence of Allograft Rejection in Allogeneic Bone Marrow Transplantation

Ying Wang, MD, Jian-Ming Li, PhD, Wayne A.C. Harris, Cynthia R. Giver, PhD, Edmund K Waller, MD PhD

Blood (2011) 118 (21): 2960.

https://doi.org/10.1182/blood.V118.21.2960.2960

Published: 2011

Journal Articles

Enrichment of Donor Plasmacytoid Dendritic Cells in Bone Marrow Allografts Enhances Graft Vs. Leukemia Activity and Th1 Polarization of Donor T Cells

Kataryna Darlak, Ying Wang, MD, Jian-Ming Li, PhD, Edmund K Waller, MD PhD

Blood (2011) 118 (21): 4701.

https://doi.org/10.1182/blood.V118.21.4701.4701

Published: 2011

Journal Articles

CD11b + gr-1 + myeloid Derived Suppressor Cells (MDSC) In Normal Bone Marrow Suppress T Cell Proliferation and Enhance T-Regulatory Function Via a IL10-, IL4- and IDO-Independent Mechanism

Parvin Forghani, Wayne Harris, jian-Ming Li, ph.D, M.R. Khorramizadeh, Associate, Professor, Edmund Waller, MD, PhD

Blood (2010) 116 (21): 4801.

https://doi.org/10.1182/blood.V116.21.4801.4801

Published: 2010

Journal Articles

Donor BM Dendritic Cells Expressing IDO Limit Graft-Versus-Host Disease After Allogeneic Bone Marrow Transplant.

Ying Lu, PhD, Wayne Harris, Jian-Ming Li, PhD, Edmund K. Waller, MD, PhD

Blood (2009) 114 (22): 1331.

https://doi.org/10.1182/blood.V114.22.1331.1331

Published: 2009

NARROW

Development of Humanized Antibodies Against Vasoactive Intestinal Polypeptide for Increased T Cell Anti-Leukemia Activity

VIP Expression Drives an Immunosuppressive Tumor Microenvironment in TP53-Mutated AML

Donor T Cell Infusions Limit Novel Immune Checkpoint Therapy in Pancreatic Cancer: Implications for Adoptive T Cell Therapy

Indole-3-Carbinol Supplement Reduces GvHD Related Mortality in Allogeneic Hematopoietic Stem Cell Transplant Recipients

High Potency Vasoactive Intestinal Peptide Receptor Antagonists Induce Durable Antileukemia/Tumor T Cell Memory in Mice with Once Daily Dosing

Donor plasmacytoid dendritic cells limit graft-versus-host disease through vasoactive intestinal polypeptide expression

Donor Plasmacytoid Dendritic Cells Regulate GvHD in a VIP Dependent Manner in Allogeneic BMT Recipients

Presence of Vasoactive Intestinal Polypeptide Signaling in Plasmacytoid Dendritic Cells Improves Survival in a Murine Allo-BMT Model

Absence of Vasoactive Intestinal Peptide Signaling Significantly Enhances T Cell Survival Following MCMV Infection Via Increased Expression of Bcl-2 and Bcl-XL

T Cell Activation By Plasmacytoid Dendritic Cells Is Augmented By Inhibition of Vasoactive Intestinal Polypeptide Signaling: Implications for Cellular Immunotherapy

Blocking VIP Signaling during Allogeneic Bone Marrow Transplantation Separates the Graft Versus Leukemia from Graft Versus Host Disease Activity of Donor CD8 T-Cells

VIP-Receptor Antagonist Enhanced Antileukemic Activity In Mice

Pharmacological inhibition of VIP signaling enhances antiviral immunity and improves survival in murine cytomegalovirus-infected allogeneic bone marrow transplant recipients

Blockade of VIP-Signaling Enhanced Anti-Leukemic Activity in Murine Allogeneic BMT without Significantly Increased GvHD.

IFN-γ and indoleamine 2,3-dioxygenase signaling between donor dendritic cells and T cells regulates graft versus host and graft versus leukemia activity

Blocking Vasoactive Intestinal Peptide Signaling Enhances Anti-Viral Immunity without Increased Graft Versus Host Disease in Murine Allogeneic Bone Marrow Transplantation

Lack of Host Bone Marrow-Derived Interleukin-12 Increased the Incidence of Allograft Rejection in Allogeneic Bone Marrow Transplantation

Enrichment of Donor Plasmacytoid Dendritic Cells in Bone Marrow Allografts Enhances Graft Vs. Leukemia Activity and Th1 Polarization of Donor T Cells

CD11b + gr-1 + myeloid Derived Suppressor Cells (MDSC) In Normal Bone Marrow Suppress T Cell Proliferation and Enhance T-Regulatory Function Via a IL10-, IL4- and IDO-Independent Mechanism

Donor BM Dendritic Cells Expressing IDO Limit Graft-Versus-Host Disease After Allogeneic Bone Marrow Transplant.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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