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Journal Articles

Enhanced Detection of Pathogenic Germline Variants in Plasma Cell Disorders: Impact of a Targeted Genetic Counseling Referral Pathway

Saoirse Bodnar, Tehilla Brander, Zachary M Avigan, William Genthe, David Melnekoff, Alessandro Lagana, Jane Houldsworth, Shambavi Richard, Joshua Richter, Larysa J Sanchez, Cesar Rodriguez, Adriana Rossi, Hearn Jay Cho, Kenan Onel, Sundar Jagannath, Manisha Balwani, Samir Parekh, Santiago Thibaud

Blood (2024) 144 (Supplement 1): 1970.

https://doi.org/10.1182/blood-2024-212204

Published: 2024

Journal Articles

Confirmed Pathogenic Germline Variants in Cancer Predisposition Genes Incidentally Detected in Somatic Genomic Profiling of Multiple Myeloma Patients

Santiago Thibaud, William Genthe, Saoirse Bodnar, Alessandro Lagana, Jane Houldsworth, Ajai Chari, Adriana C Rossi, Cesar Rodriguez, Larysa J Sanchez, Shambavi Richard, Joshua Richter, Kenan Onel, Sundar Jagannath, Tehilla Brander, Samir Parekh

Blood (2023) 142 (Supplement 1): 534.

https://doi.org/10.1182/blood-2023-190878

Published: 2023

Journal Articles

T-Cell Monoclonality As Assessed By TCR-Sequencing: A Potential Biomarker of Response in Patients with MDS with Autoimmune Cytopenias Treated with IVIG

Jonathan Feld, MD, Jane Houldsworth, PhD, Asha Reddy, MS, Zinnia Mai, BS, Shafinaz Hussein, MD, Shyamala C. Navada, MD, Lewis R. Silverman, MD, Meenakshi Mehrotra, PhD

Blood (2020) 136 (Supplement 1): 8–9.

https://doi.org/10.1182/blood-2020-143083

Published: 2020

Journal Articles

Expansion of Prior Existing TP53 Mutated Clones in Polycythemia Vera Patients Treated with Idasanutlin

Bridget Marcellino, MD PhD, Bruno Cassinat, PharmD, PhD, Noushin Farnoud, PhD, Min Lu, PhD, Emmanuelle Verger, PhD, Erin McGovern, BA, Minal A Patel, MPH, Heidi E. Kosiorek, MS, Meenakshi Mehrotra, PhD, Jane Houldsworth, PhD, Amylou C. Dueck, PhD, Michael Rossi, PhD, Jean-Jacques Kiladjian, MD PhD, Raajit K. Rampal, MD PhD, John Mascarenhas, MD, Ronald Hoffman, MD

Blood (2019) 134 (Supplement_1): 838.

https://doi.org/10.1182/blood-2019-128342

Published: 2019

Journal Articles

Precision in PD-L1 Assessment in Diffuse Large B Cell Lymphoma: Greater Biological Insight Using in Situ Hybridization Approach

Imran Siddiqi, MDPhD, Venkata Thodima, PhD, Kishor Bhatia, PhD, Jane Houldsworth, PhD, Rita Shaknovich, MD PhD

Blood (2017) 130 (Supplement 1): 1477.

https://doi.org/10.1182/blood.V130.Suppl_1.1477.1477

Published: 2017

Journal Articles

PD-L1 Expression Identifies High Risk Diffuse Large B-Cell Lymphoma and Is Associated with Several Genomic Markers

Imran N Siddiqi, MD PhD, Venkata Thodima, PhD, Julia Friedman, PhD, Adames Violeta, Anil Tulpule, MD, Rita Shaknovich, MD PhD, Jane Houldsworth, PhD

Blood (2016) 128 (22): 153.

https://doi.org/10.1182/blood.V128.22.153.153

Published: 2016

Journal Articles

A 220-Gene Targeted Next-Generation Sequencing Panel for the Detection of Variants in Diffuse Large B-Cell Lymphoma, Follicular Lymphoma, and Mantle Cell Lymphoma: Application to a Cohort of 85 Formalin-Fixed Paraffin-Embedded Diffuse Large B-Cell Lymphoma Biopsies

Julia Friedman, PhD, Asha Guttapalli, M.Sc., Charles Ma, PhD, Venkata Thodima, PhD, Raghavendra Padmanabhan, Sitharthan Kamalakaran, PhD, Imran N Siddiqi, MD PhD, Jane Houldsworth, PhD

Blood (2015) 126 (23): 1470.

https://doi.org/10.1182/blood.V126.23.1470.1470

Published: 2015

Journal Articles

Systematic Analysis of Cell-of-Origin, Sequencing and Genomic Imbalances Identifies a Distinct Subset of Rituximab Treated Diffuse Large B-Cell Lymphoma with an Inferior Survival

Rajan Dewar, MD PhD, Julia Friedman, PhD, Daniel Xia, MD, Timothy George Lens, Asha Guttapalli, M.Sc., Phillip Michaels, MD, Venkata Thodima, PhD, Sitharthan Kamalakaran, PhD, Jane Houldsworth, PhD, Robin Joyce, MD

Blood (2015) 126 (23): 3910.

https://doi.org/10.1182/blood.V126.23.3910.3910

Published: 2015

Journal Articles

Genomic Complexity in Diffuse Large B-Cell Lymphoma Is Associated with p53 Expression and Inferior Survival

Charles Ma, PhD, Imran N Siddiqi, MD PhD, Yi Xie, MD PhD, Anil Tulpule, MD, Jane Houldsworth, PhD

Blood (2014) 124 (21): 3023.

https://doi.org/10.1182/blood.V124.21.3023.3023

Published: 2014

Journal Articles

Robust Assessment of Genomic Imbalance in Diffuse Large B-Cell Lymphoma Confirms Inferior Outcome Is Associated with Genomic Complexity and Identifies Potential Therapeutic Pathway Targets

Lizalynn Dias, PhD, Venkata Thodima, PhD, Asha Guttapalli, M.S., Geetu Mendiratta, PhD, Sergei I Syrbu, MD, Jane Houldsworth, PhD

Blood (2014) 124 (21): 2993.

https://doi.org/10.1182/blood.V124.21.2993.2993

Published: 2014

Journal Articles

Cross-Platform Assessment Of Genomic Imbalance In Diffuse Large B-Cell Lymphoma Identifies Novel Candidate Loci and Genes With Prognostic Value and Roles In Lymphomagenesis

Lizalynn Dias, Ph.D., Venkata Thodima, Ph.D., Geetu Mendiratta, Ph.D., Guttapalli Asha, M.S., Camille Gonzalez, Jocelyn C. Maragulia, Andrew D. Zelenetz, MD, PhD, Julie Teruya Feldstein, MD, Raju S.K. Chaganti, PhD, FACMG, Jane Houldsworth, PhD

Blood (2013) 122 (21): 4259.

https://doi.org/10.1182/blood.V122.21.4259.4259

Published: 2013

Journal Articles

Targeted Oligonucleotide Array Assessment of Genomic Copy Number Alterations for Risk Stratification in Chronic Lymphocytic Leukemia

Jane Houldsworth, PhD, Asha Guttapalli, MS, Xiao J. Yan, MD, PhD, Charles Ma, PhD, Weiyi Chen, PhD, Sujata Patil, PhD, Kanti R Rai, MD, Nicholas Chiorazzi, M.D.

Blood (2011) 118 (21): 1773.

https://doi.org/10.1182/blood.V118.21.1773.1773

Published: 2011

Journal Articles

Members of the glutathione and ABC-transporter families are associated with clinical outcome in patients with diffuse large B-cell lymphoma

Charalambos Andreadis, Phyllis A. Gimotty, Peter Wahl, Rachel Hammond, Jane Houldsworth, Stephen J. Schuster, Timothy R. Rebbeck

Blood (2006) 109 (8): 3409–3416.

https://doi.org/10.1182/blood-2006-09-047621

Published: 2006

Journal Articles

Expression Levels of Glutathione Peroxidase 1 (GPx1) and Multi-Drug Resistance 1 (MDR1; ABCB1) Identify Patients with Diffuse Large B-Cell Lymphoma (DLBCL) That Have Superior Clinical Outcomes.

Charalambos Andreadis, Phyllis Gimotty, Rachel Hammond, Peter Wahl, Jane Houldsworth, Stephen Schuster, Timothy Rebbeck

Blood (2006) 108 (11): 839.

https://doi.org/10.1182/blood.V108.11.839.839

Published: 2006

Journal Articles

Array comparative genomic hybridization reveals genomic copy number changes associated with outcome in diffuse large B-cell lymphomas

Weiyi Chen, Jane Houldsworth, Adam B. Olshen, Gouri Nanjangud, Seeta Chaganti, Ennapadem S. Venkatraman, Jeffrey Halaas, Julie Teruya-Feldstein, Andrew D. Zelenetz, R. S. K. Chaganti

Blood (2006) 107 (6): 2477–2485.

https://doi.org/10.1182/blood-2005-07-2950

Published: 2006

Includes: Supplemental data

Journal Articles

Inactivation of the PRDM1/BLIMP1 Gene in Non-GC-Type Diffuse Large B-Cell Lymphoma.

Laura Pasqualucci, MD, Mara Compagno, PhD, Jane Houldsworth, PhD, Stefano Monti, PhD, Adina Grunn, Margaret A. Shipp, MD, Riccardo Dalla-Favera, MD

Blood (2005) 106 (11): 2614.

https://doi.org/10.1182/blood.V106.11.2614.2614

Published: 2005

Journal Articles

Cell of origin, germinal center versus nongerminal center, determined by immunohistochemistry on tissue microarray, does not correlate with outcome in patients with relapsed and refractory DLBCL

Craig H. Moskowitz, Andrew D. Zelenetz, Tarun Kewalramani, Paul Hamlin, Simone Lessac-Chenen, Jane Houldsworth, Adam Olshen, Raju Chaganti, Stephen Nimer, Julie Teruya-Feldstein

Blood (2005) 106 (10): 3383–3385.

https://doi.org/10.1182/blood-2005-04-1603

Published: 2005

Journal Articles

Identification of Genetic and Expression Markers in DLBCL Cell Lines That Influence the In Vivo Response of DLBCL to Doxorubicin.

Jane Houldsworth, PhD, Marina Petlakh, MS, R. S. Chaganti, PhD

Blood (2004) 104 (11): 700.

https://doi.org/10.1182/blood.V104.11.700.700

Published: 2004

Journal Articles

Clinical Outcome Correlations of Genomic Gains and Losses in Diffuse Large B-Cell Lymphoma by Array-CGH.

Weiyi Chen, Ph.D., Adam Olsen, Ph.D., Seeta Chaganti, Ph.D., Jeff Halaas, M.D., Andrew D. Zelenetz, M.D., Julie Feldstein, M.D., Jane Houldsworth, Ph.D., Raju S.K. Chaganti, Ph.D.

Blood (2004) 104 (11): 30.

https://doi.org/10.1182/blood.V104.11.30.30

Published: 2004

Journal Articles

Expression of the AID protein in normal and neoplastic B cells

Laura Pasqualucci, Roberta Guglielmino, Jane Houldsworth, Jessica Mohr, Said Aoufouchi, Roberto Polakiewicz, R. S. K. Chaganti, Riccardo Dalla-Favera

Blood (2004) 104 (10): 3318–3325.

https://doi.org/10.1182/blood-2004-04-1558

Published: 2004

Includes: Supplemental data

NARROW

Enhanced Detection of Pathogenic Germline Variants in Plasma Cell Disorders: Impact of a Targeted Genetic Counseling Referral Pathway

Confirmed Pathogenic Germline Variants in Cancer Predisposition Genes Incidentally Detected in Somatic Genomic Profiling of Multiple Myeloma Patients

T-Cell Monoclonality As Assessed By TCR-Sequencing: A Potential Biomarker of Response in Patients with MDS with Autoimmune Cytopenias Treated with IVIG

Expansion of Prior Existing TP53 Mutated Clones in Polycythemia Vera Patients Treated with Idasanutlin

Precision in PD-L1 Assessment in Diffuse Large B Cell Lymphoma: Greater Biological Insight Using in Situ Hybridization Approach

PD-L1 Expression Identifies High Risk Diffuse Large B-Cell Lymphoma and Is Associated with Several Genomic Markers

A 220-Gene Targeted Next-Generation Sequencing Panel for the Detection of Variants in Diffuse Large B-Cell Lymphoma, Follicular Lymphoma, and Mantle Cell Lymphoma: Application to a Cohort of 85 Formalin-Fixed Paraffin-Embedded Diffuse Large B-Cell Lymphoma Biopsies

Systematic Analysis of Cell-of-Origin, Sequencing and Genomic Imbalances Identifies a Distinct Subset of Rituximab Treated Diffuse Large B-Cell Lymphoma with an Inferior Survival

Genomic Complexity in Diffuse Large B-Cell Lymphoma Is Associated with p53 Expression and Inferior Survival

Robust Assessment of Genomic Imbalance in Diffuse Large B-Cell Lymphoma Confirms Inferior Outcome Is Associated with Genomic Complexity and Identifies Potential Therapeutic Pathway Targets

Cross-Platform Assessment Of Genomic Imbalance In Diffuse Large B-Cell Lymphoma Identifies Novel Candidate Loci and Genes With Prognostic Value and Roles In Lymphomagenesis

Targeted Oligonucleotide Array Assessment of Genomic Copy Number Alterations for Risk Stratification in Chronic Lymphocytic Leukemia

Members of the glutathione and ABC-transporter families are associated with clinical outcome in patients with diffuse large B-cell lymphoma

Expression Levels of Glutathione Peroxidase 1 (GPx1) and Multi-Drug Resistance 1 (MDR1; ABCB1) Identify Patients with Diffuse Large B-Cell Lymphoma (DLBCL) That Have Superior Clinical Outcomes.

Array comparative genomic hybridization reveals genomic copy number changes associated with outcome in diffuse large B-cell lymphomas

Inactivation of the PRDM1/BLIMP1 Gene in Non-GC-Type Diffuse Large B-Cell Lymphoma.

Cell of origin, germinal center versus nongerminal center, determined by immunohistochemistry on tissue microarray, does not correlate with outcome in patients with relapsed and refractory DLBCL

Identification of Genetic and Expression Markers in DLBCL Cell Lines That Influence the In Vivo Response of DLBCL to Doxorubicin.

Clinical Outcome Correlations of Genomic Gains and Losses in Diffuse Large B-Cell Lymphoma by Array-CGH.

Expression of the AID protein in normal and neoplastic B cells

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American Society of Hematology

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American Society of Hematology

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