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Journal Articles

Single-Cell Transcriptional Characteristics of the Unresponsive Cluster Surviving Anergy in IGHV1-69 CLL

Stuart Lanham, Luis Del Rio Fernandez, Stefano de Pretis, Joshua Grant, Isla Henderson, Benjamin Sale, Lauren Griffith, David Dutton, Giovanni Tonon, Freda K. Stevenson, Francesco Forconi
Journal: Blood
Blood (2024) 144 (Supplement 1): 1847.
https://doi.org/10.1182/blood-2024-210464
Published: 2024
Journal Articles

Analysis of Single B Cells Reveals a Double Drive of Endocytosis and Transcriptional Downregulation Acting on the CLL B-Cell Receptor In Vivo

Stuart Lanham, Luis Del Rio Fernandez, Joshua Grant, Isla Henderson, Ben Sale, Dean J. Bryant, Lauren Griffith, Alberto Orfao, Freda K. Stevenson, Francesco Forconi
Journal: Blood
Blood (2023) 142 (Supplement 1): 6508.
https://doi.org/10.1182/blood-2023-188571
Published: 2023
Journal Articles

Insertion of atypical glycans into the tumor antigen-binding site identifies DLBCLs with distinct origin and behavior

Giorgia Chiodin, Joel D. Allen, Dean J. Bryant, Philip Rock, Enrica A. Martino, Beatriz Valle-Argos, Patrick J. Duriez, Yasunori Watanabe, Isla Henderson, James S. Blachly, Katy J. McCann, Jonathan C. Strefford, Graham Packham, Teunis B. H. Geijtenbeek, Carl G. Figdor, George W. Wright, Louis M. Staudt, Richard Burack, Thomas A. Bowden, Max Crispin, Freda K. Stevenson, Francesco Forconi
Journal: Blood
Blood (2021) 138 (17): 1570–1582.
https://doi.org/10.1182/blood.2021012052
Published: 2021
Includes: Supplemental data
Journal Articles

High Surface IgM Levels Associate with Shorter Response Duration and Bypass of the BTK Blockade during Ibrutinib Therapy in CLL Patients

Giorgia Chiodin, David Dutton, MD, Enrica Antonia Martino, MD, Samantha Drennan, PhD, Ian Tracy, PhD, Laura Ondrisova, Isla Henderson, Annalisa D'Avola, PhD, Christina Pitsillidou, Marek Mraz, MD, Peter Johnson, MDFRCP, Andrew Duncombe, MD, Graham Packham, PhD, Andrew J Steele, PhD, Helen Parker, PhD, Silvia Bonfiglio, Lydia Scarfo, MD, Lesley-Ann Sutton, Paolo Ghia, MD PhD, Matthew John Jerome Rose-Zerilli, PhD, Jonathan C Strefford, PhD, Freda K. Stevenson, DPhil, Francesco Forconi, MD DM, PhD FRCPath
Journal: Blood
Blood (2019) 134 (Supplement_1): 1752.
https://doi.org/10.1182/blood-2019-128899
Published: 2019
Journal Articles

Surface IgM expression and function are associated with clinical behavior, genetic abnormalities, and DNA methylation in CLL

Clinical Trials & Observations
Annalisa D’Avola, Samantha Drennan, Ian Tracy, Isla Henderson, Laura Chiecchio, Marta Larrayoz, Matthew Rose-Zerilli, Jonathan Strefford, Christoph Plass, Peter W. Johnson, Andrew J. Steele, Graham Packham, Freda K. Stevenson, Christopher C. Oakes, Francesco Forconi
Journal: Blood
Blood (2016) 128 (6): 816–826.
https://doi.org/10.1182/blood-2016-03-707786
Published: 2016
Includes: Supplemental data
Journal Articles

Surface IgM Levels Independently Influence Clinical Behavior and Associate with Altered Phenotype and Genetics in Chronic Lymphocytic Leukemia

Samantha J Drennan, PhD, Annalisa D'Avola, MSc, Ian Tracy, Isla Henderson, Marta Larrayoz, PhD, Carina Mundy, Andrew S. Duncombe, MD, Andrew J. Davies, MD PhD, Davide Rossi, MD PhD, Fiona M Ross, DPhil, Laura Chiecchio, PhD, Kathleen N. Potter, PhD, Jonathan Strefford, PhD, Andrew J Steele, PhD, Peter W Johnson, MD, Graham Packham, PhD, Freda K Stevenson, DPhil, Francesco Forconi, MD DM, PhD FRCPath
Journal: Blood
Blood (2014) 124 (21): 830.
https://doi.org/10.1182/blood.V124.21.830.830
Published: 2014
Journal Articles

The IGHV1-69/IGHJ3 recombinations of unmutated CLL are distinct from those of normal B cells

Brief Report
Francesco Forconi, Kathleen N. Potter, Elisa Sozzi, Isla Henderson, Emanuele Cencini, Davide Rossi, Riccardo Bomben, Valter Gattei, Gianluca Gaidano, Graham Packham, Freda K. Stevenson
Journal: Blood
Blood (2012) 119 (9): 2106–2109.
https://doi.org/10.1182/blood-2011-08-375501
Published: 2012
Includes: Supplemental data