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Journal Articles

Long-Term Effects of Belantamab Mafodotin Plus Bortezomib, Lenalidomide and Dexamethasone (VRd) on T Cell Exhaustion Phenotype

Mauro Lorenzo, Juan-José Garcés, Leire Burgos, Irene Manrique, Marta Lasa, Noemi Puig, Janet Sotolongo-Ravelo, Marta González-Rodríguez, Bárbara Castellanos, Maria Teresa Cedena Romero, Bruno Paiva, Veronica Gonzalez-Calle, Maria-Victoria Mateos, Mercedes Garayoa, Teresa Paíno
Journal: Blood
Blood (2024) 144 (Supplement 1): 6866.
https://doi.org/10.1182/blood-2024-209686
Published: 2024
Journal Articles

Expanding the Eureka Study: Integrating a Comprehensive Clinical Registry with Molecular Profiling to Advance AL Amyloidosis Research

Mario Nuvolone, Ute Hegenbart, Bruno Paiva, Monique C. Minnema, Enkelejda Miho, Marta Lasa, Paolo Milani, Alain van Mil, Marish I. F. Oerlemans, Jan Kruta, Ramon Lecumberri Villamediana, Alice Nevone, Luca Arcaini, Francesca Gay, Francesco Di Raimondo, Pellegrino Musto, Eloisa Riva, Mohammed Aljama, Krzysztof Jamroziak, Roberta Shcolnik Szor, Mathias Brehon, Giampaolo Merlini, Stefan Schonland, Giovanni O. Palladini
Journal: Blood
Blood (2024) 144 (Supplement 1): 1927.1.
https://doi.org/10.1182/blood-2024-200529
Published: 2024
Journal Articles

Clinical Significance of Measurable Residual Disease (MRD) in Light-Chain (AL) Amyloidosis

Marta Lasa, Mario Nuvolone, Ioannis V Kostopoulos, Tomas Jelinek, Marco Basset, Paolo Milani, Margherita Massa, Foteini Theodorakakou, Ashutosh D. Wechalekar, Anastasiia Zherniakova, Rafael Ríos, Irene Romera, Maria Teresa Cedena Romero, Noemi Puig, Ramon Lecumberri Villamediana, Jesús F. San-Miguel, Roman Hajek, Giampaolo Merlini, Efstathios Kastritis, Bruno Paiva, Giovanni O. Palladini
Journal: Blood
Blood (2024) 144 (Supplement 1): 889.
https://doi.org/10.1182/blood-2024-202995
Published: 2024
Journal Articles

A CD38/CD28xCD3 Trispecific T-Cell Engager (TCE) As a Potentially Active Agent in Multiple Myeloma Patients Relapsed and/or Refractory (RRMM) to Anti-CD38 Monoclonal Antibodies (mAbs)

Aintzane Zabaleta, Laura Blanco, Peter Kim, Kamlesh Bisht, Hongfang Wang, Helgi J. Van de Velde, Marta Lasa, Luis-Esteban Tamariz-Amador, Paula Rodriguez Otero, Jesús San Miguel, Bruno Paiva, Esperanza Martín-Sánchez
Journal: Blood
Blood (2023) 142 (Supplement 1): 1921.
https://doi.org/10.1182/blood-2023-182150
Published: 2023
Journal Articles

Minimally Invasive Assessment of Measurable Residual Disease (MRD) in Multiple Myeloma (MM)

Carmen Gonzalez, Marta Lasa, Laura Notarfranchi, Cristina Agullo, Natalia Buenache Cuenda, Anastasiia Zherniakova, Sergio Castro, José Juan Pérez, Veronica Gonzalez-Calle, Maria Teresa Cedena Romero, Santiago Barrio, Alejandro Martín-Muñoz, Leire Burgos, Diego Alignani, Maria Jose Calasanz, Paula Rodriguez Otero, Laura Rosiñol, Felipe De Arriba, Enrique M Ocio, Albert Oriol Rocafiguera, Luis Palomera, Yolanda González-Montes, Anna Maria Sureda Balari, Miguel Teodoro Hernandez Garcia, Maria Esther Clavero Sanchez, Angela Ibanez Garcia, Clara Gomez, Alberto Orfao, Maria Victoria Mateos, Juan Jose Lahuerta Palacios, Joan Bladé, Jesus San-Miguel, Joaquin Martinez-Lopez, Noemi Puig, Bruno Paiva
Journal: Blood
Blood (2023) 142 (Supplement 1): 339.
https://doi.org/10.1182/blood-2023-186916
Published: 2023
Journal Articles

Biological and Clinical Significance of Undetectable Circulating Tumor Cells (CTCs) in Patients (Pts) with Multiple Myeloma (MM)

Juan-José Garcés, Rosalinda Termini, Esperanza Martín-Sánchez, Marta Lasa, Jose J Perez, Norma C. Gutierrez, Manuela Fernández, Maria Jose Calasanz, Laura Rosiñol, Miguel Teodoro Hernández Garcia, Albert Oriol, Anna Maria Sureda Balari, Albert Perez Montaña, Enrique M Ocio, Maria Casanova Espinosa, Felipe Prosper, Joaquin Martinez-Lopez, Jorge Labrador, Esther Gonzalez Garcia, Rafael Ríos, Fernando Escalante, Joan Bargay, Elena Cabezudo, Valentín Cabañas, Niels Weinhold, Aldo Roccaro, Herve Avet-Loiseau, Alberto Orfao, Joan Blade Creixenti, Maria Victoria Mateos, Juan Jose Lahuerta Palacios, Jesus San-Miguel, María T Cedena, Noemi Puig, Bruno Paiva
Journal: Blood
Blood (2023) 142 (Supplement 1): 646.
https://doi.org/10.1182/blood-2023-186411
Published: 2023
Journal Articles

Ultra-Sensitive Assessment of Measurable Residual Disease (MRD) in Peripheral Blood (PB) of Multiple Myeloma (MM) Patients Using Bloodflow

Laura Notarfranchi, Anastasiia Zherniakova, Marta Lasa, Noemi Puig, María Teresa Cedena, Joaquin Martinez-Lopez, María José Calasanz, Diego Alignani, Leire Burgos, Irene Manrique, Yi-Ju Huang, Jochen Fracowiak, Clara Gomez, Felipe De Arriba, Paula Rodríguez-Otero, Luis Palomera, Anna Sureda, Maria Esther Clavero Sanchez, Miguel Angel Alvarez, Angela Ibanez Garcia, Miguel-Teodoro Hernández, Albert Perez, Ana Pilar Gonzalez, Enrique M. Ocio, Juan Flores-Montero, Alberto Orfao, Juan Jose Lahuerta, María-Victoria Mateos, Laura Rosiñol, Joan Bladé Creixenti, Jesús San-Miguel, Bruno Paiva
Journal: Blood
Blood (2022) 140 (Supplement 1): 2095–2097.
https://doi.org/10.1182/blood-2022-167382
Published: 2022
Journal Articles

CAR-T Related Cytopenia Profile in Relapsed/Refractory Multiple Myeloma: Results of Patients Treated with ARI0002h, an Academic BCMA-Directed CAR-T Cell

Aina Oliver-Caldes, Luis Gerardo Rodríguez-Lobato, Veronica Gonzalez-Calle, Natalia Tovar, Valentin Cabañas, Paula Rodríguez-Otero, Juan Luis Reguera, Marta Español-Rego, Beatriz Martin-Antonio, Aintzane Zabaleta, Marta Lasa, Susana Inogés, Ascensión López-Diaz de Cerio, Bruno Paiva, Sara Varea, Joaquin Saez-Peñataro, Manel Juan, Laura Rosiñol, Felipe Prosper, Jose M. Moraleda, Álvaro Urbano-Ispizua, Mariona Pascal, Maria-Victoria Mateos, Carlos Fernandez de Larrea
Journal: Blood
Blood (2022) 140 (Supplement 1): 10347–10349.
https://doi.org/10.1182/blood-2022-166525
Published: 2022
Journal Articles

Definition and Clinical Significance of the MGUS-like Phenotype: A Study in 5,114 Patients (Pts) with Monoclonal Gammopathies

Leire Burgos, Luis Esteban Tamariz-Amador, Noemí Puig, María Teresa Cedena, Tomas Jelinek, Sarah K Johnson, Paolo Milani, Lourdes Cordon, José J Pérez, Marta Lasa, Rosalinda Termini, Albert Oriol, Miguel-Teodoro Hernández, Luis Palomera, Rafael Martinez Martinez, Javier de la Rubia, Felipe De Arriba, Rafael Rios, Maria Esther González, Mercedes Gironella, Valentin Cabañas, Maria Casanova, Isabel Krsnik, Albert Pérez, Veronica Gonzalez De La Calle, Paula Rodríguez-Otero, Vladimir Maisnar, Roman Hajek, Frits van Rhee, Victor H Jimenez-Zepeda, Giovanni Palladini, Paolo Milani, Alberto Orfao, Laura Rosinol, Joan Bladé Creixenti, Joaquín Martínez-López, Juan-José Lahuerta, Maria-Victoria Mateos, Jesús F. San-Miguel, Bruno Paiva
Journal: Blood
Blood (2021) 138 (Supplement 1): 541.
https://doi.org/10.1182/blood-2021-150092
Published: 2021
Journal Articles

Correlative Biological Studies Related to the Response, Peak and Persistence of ARI0002h, an Academic BCMA-Directed CAR-T Cell, with Fractionated Initial Infusion and Booster Dose for Patients with Relapsed and/or Refractory Multiple Myeloma (RRMM)

Aina Oliver-Caldés, Marta Español-Rego, Aintzane Zabaleta, Susana Inogés, Ascensión López-Diaz de Cerio, Veronica Gonzalez-Calle, Valentin Cabañas, Beatriz Martin-Antonio, Lorena Pérez-Amill, Juan Luis Reguera, Juan Roberto Rodriguez-Madoz, Paula Rodríguez-Otero, Daniel Benítez-Ribas, Mari-Pau Mena, Marta Lasa, Luis Gerardo Rodríguez-Lobato, Azucena González, Laura Rosinol, Jose Maria Moraleda, Felipe Prósper, Álvaro Urbano-Ispizua, Maria-Victoria Mateos, Manel Juan, Bruno Paiva, Mariona Pascal, Carlos Fernandez de Larrea
Journal: Blood
Blood (2021) 138 (Supplement 1): 552.
https://doi.org/10.1182/blood-2021-148281
Published: 2021
Journal Articles

Tumor cells in light-chain amyloidosis and myeloma show distinct transcriptional rewiring of normal plasma cell development

CME Brief Report
Daniel Alameda, Ibai Goicoechea, Marco Vicari, Elena Arriazu, Alice Nevone, Sara Rodriguez, Marta Lasa, Noemi Puig, Maria Teresa Cedena, Diego Alignani, Sonia Garate, David Lara-Astiaso, Amaia Vilas-Zornoza, Sarai Sarvide, Enrique M. Ocio, Ramon Lecumberri, Alfonso Garcia de Coca, Jorge Labrador, Maria-Esther Gonzalez, Luis Palomera, Mercedes Gironella, Valentin Cabañas, Maria Casanova, Albert Oriol, Isabel Krsnik, Albert Perez-Montaña, Javier de la Rubia, Jose-Enrique de la Puerta, Felipe de Arriba, Vito Michele Fazio, Joaquin Martinez-Lopez, Juan-Jose Lahuerta, Maria-Victoria Mateos, Maria-Dolores Odero, Felipe Prosper, Assaf Weiner, Ido Amit, Mario Nuvolone, Jesus F. San Miguel, Bruno Paiva
Journal: Blood
Blood (2021) 138 (17): 1583–1589.
https://doi.org/10.1182/blood.2020009754
Published: 2021
Includes: Supplemental data
Journal Articles

Predictive Biomarkers of Response to Venetoclax in Combination with Cobimetinib in Relapsed/Refractory Multiple Myeloma (RRMM)

Aparna Raval, Habib Hamidi, Olivia Hwang, Cherie Green, Catarina Maia, Marta Lasa, Maika Onishi, Paula Rodriguez-Otero, Jesús F. San-Miguel, Jorge D. Gallo, Bruno Paiva, PhD, Fredrik Schjesvold, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 30–31.
https://doi.org/10.1182/blood-2020-134910
Published: 2020
Journal Articles

Multidimensional Immunophenotyping Identifies Hallmarks of Systemic Light-Chain Amyloidosis (AL) and Maps the Disease in the Crossroad between MGUS and Multiple Myeloma (MM)

Noemi Puig, MD PhD, Bruno Paiva, MD PhD, Marta Lasa, Leire Burgos, José J Pérez, Juana Merino, Cristina Moreno, Maria-Belen Vidriales, MD, Dolores Gómez, María Teresa Cedena, Enrique M. Ocio, MD, Ramon Lecumberri, MD PhD, Alfonso García de Coca, MD PhD, Jorge Labrador, MD, Esther González Garcia, MD, Luis Palomera, MD PhD, Mercedes Gironella, MD, Valentin Cabañas, MD, Maria Casanova, MD, Albert Oriol, MD, Isabel Krsnik, MD PhD, Albert Pérez, MD, Javier De La Rubia, MD, José Enrique de la Puerta, Felipe De Arriba, PhD, Felipe Prosper, MD PhD, Joaquin Martinez Lopez, MD PhD, Quentin Lecrevisse, Javier Verde, Maria-Victoria Mateos, MD PhD, Juan Jose Lahuerta, MD PhD, Alberto Orfao, MD PhD, Jesús F San-Miguel, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3170.
https://doi.org/10.1182/blood-2018-99-119281
Published: 2018
Journal Articles

Genetic Profiling and Novel Recurrent Chromosomal Alterations in Patients with Light Chain Amyloidosis

Isabel Cuenca, MSc, Beatriz Sanchez-Vega, PhD, Bruno Paiva, MD PhD, David Gomez-Sanchez, Santiago Barrio, PhD, Diego Alignani, PhD, Marta Lasa, Ramon Lecumberri, MD PhD, Felipe Prosper, MD PhD, Enrique M. Ocio, MD, Maria Esther González, Alfonso García de Coca, MD PhD, Javier De La Rubia, MD, Mercedes Gironella, MD, Luis Palomera, MD PhD, Albert Oriol, MD, Maria Casanova, MD, Valentin Cabañas, MD, Francisco Taboada, PhD, Albert Pérez, MD, Felipe De Arriba, PhD, Noemi Puig, MD PhD, Juan Jose Lahuerta, MD PhD, Maria-Victoria Mateos, MD PhD, Jesus F San-Miguel, MD PhD, Joaquin Martinez Lopez, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4488.
https://doi.org/10.1182/blood-2018-99-114543
Published: 2018
Journal Articles

Understanding the Cellular Origin and Pathogenic Transcriptional Programs in Multiple Myeloma (MM) and Light-Chain Amyloidosis (AL) through the Dissection of the Normal Plasma Cell (PC) Development

Daniel Alameda, PhD, Marco Vicari, MD, David Lara-Astiaso, PhD, Marta Lasa, Noemi Puig, MD PhD, Maria Teresa Cedena Romero, MD PhD, Idoia Rodriguez, Diego Alignani, PhD, Amaia Vilas-Zornoza, PhD, Ibai Goicoechea, PhD, Sarai Sarvide, Enrique M. Ocio, MD, Ramon Lecumberri, MD PhD, Alfonso García de Coca, MD PhD, Jorge Labrador, MD, Esther González Garcia, MD, Luis Palomera, MD PhD, Mercedes Gironella, MD, Valentin Cabañas, MD, Maria Casanova, MD, Albert Oriol, MD, Isabel Krsnik, MD PhD, Albert Pérez, MD, Joaquin Martinez Lopez, MD PhD, Maria-Victoria Mateos, MD PhD, Juan-José Lahuerta, MD PhD, Felipe Prosper, MD PhD, Assaf Weiner, PhD, Ido Amit, PhD, Jesús F San-Miguel, MD, Bruno Paiva, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 188.
https://doi.org/10.1182/blood-2018-188
Published: 2018
Journal Articles

Pre-Clinical Efficacy of the Anti-CD38 Monoclonal Antibody (mAb) Isatuximab in Acute Myeloid Leukemia (AML)

Tomas Jelinek, Aintzane Zabaleta, PhD, Cristina Perez, Daniel Ajona, PhD, Diego Alignani, PhD, Idoia Rodriguez, Sonia Garate, Sarai Sarvide, Marta Lasa, Patricia Maiso, PhD, Felipe Prosper, MDPhD, Roman Hajek, Jesus F. San Miguel, MD, Bruno Paiva, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2655.
https://doi.org/10.1182/blood.V130.Suppl_1.2655.2655
Published: 2017
Journal Articles

New Insights into the Mechanism of Action (MoA) of First-in-Class IgG-Based Bcma T-Cell Bispecific Antibody (TCB) for the Treatment of Multiple Myeloma (MM)

Laura Moreno, Aintzane Zabaleta, Diego Alignani, Marta Lasa, Patricia Maiso, PhD, Tomas Jelinek, MD, Victor Segura, PhD, Jose Antonio Delgado, Paula Rodriguez-Otero, MD PhD, Felipe Prosper, MD, Klaus Strein, MD PhD, Minh Diem Vu, PhD, Jesus San Miguel, MD PhD, Bruno Paiva, PhD
Journal: Blood
Blood (2016) 128 (22): 2096.
https://doi.org/10.1182/blood.V128.22.2096.2096
Published: 2016
Journal Articles

Critical Analysis on the Mechanism of Action (MoA) of the Anti-CD38 Monoclonal Antibody Isatuximab in Multiple Myeloma (MM)

Laura Moreno, Aintzane Zabaleta, Diego Alignani, Daniel Ajona, Marta Lasa, Patricia Maiso, PhD, Tomas Jelinek, MD, Victor Segura, PhD, Jose Antonio Delgado, Paula Rodriguez-Otero, MD PhD, Felipe Prosper, MD, Jesus San Miguel, MD PhD, Bruno Paiva, PhD
Journal: Blood
Blood (2016) 128 (22): 2105.
https://doi.org/10.1182/blood.V128.22.2105.2105
Published: 2016
Journal Articles

High-Throughput Characterization and New Insight into the Role of Tumor Associated Macrophages (TAMs) in Multiple Myeloma (MM)

Paula Arana, Aintzane Zabaleta, Marta Lasa, Patricia Maiso, PhD, Diego Alignani, Tomas Jelinek, MD, Victor Segura, PhD, Wouter van den Bossche, Cristina Teodosio, Daniela Damasceno, Paula Rodriguez-Otero, MD PhD, Felipe Prosper, MD, Maria-Victoria Mateos, MD PhD, Juan Jose Lahuerta, Joan Bladé, Jacques J.M. van Dongen, MD PhD, Jesus San Miguel, MD PhD, Alberto Orfao, MD PhD, Bruno Paiva, PhD
Journal: Blood
Blood (2016) 128 (22): 482.
https://doi.org/10.1182/blood.V128.22.482.482
Published: 2016
Journal Articles

Phenotypic, transcriptomic, and genomic features of clonal plasma cells in light-chain amyloidosis

Brief Report
Bruno Paiva, Joaquin Martinez-Lopez, Luis A. Corchete, Beatriz Sanchez-Vega, Inmaculada Rapado, Noemi Puig, Santiago Barrio, Maria-Luz Sanchez, Diego Alignani, Marta Lasa, Alfonso García de Coca, Emilia Pardal, Alberto Oriol, Maria-Esther Gonzalez Garcia, Fernando Escalante, Tomás J. González-López, Luis Palomera, José Alonso, Felipe Prosper, Alberto Orfao, Maria-Belen Vidriales, María-Victoria Mateos, Juan-Jose Lahuerta, Norma C. Gutierrez, Jesús F. San Miguel
Journal: Blood
Blood (2016) 127 (24): 3035–3039.
https://doi.org/10.1182/blood-2015-10-673095
Published: 2016
Includes: Supplemental data