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Journal Articles

Spatiotemporal and genetic tracking of long-term persisting CAR-T cells following ciltacabtagene autoleucel treatment for multiple myeloma reveals molecular insights into late-onset toxicities

Free
David Fandrei, Sabine Seiffert, Christina Kuhn, Michael Rade, Esmée van Vliet, Vera von Landenberg-Roberg, Manja Meggendorfer, Luise Fischer, Markus Kreuz, Dennis Löffler, Conny Blumert, Anja Grahnert, Maik Friedrich, Patrick Born, Thomas Wiemers, Emilie-Charlot Skerbek, Kathrin Jäger, Sebastian Greiser, Ronny Baber, Song-Yau Wang, Simone Heyn, Georg-Nikolaus Franke, Andreas Boldt, Dominik Schmiedel, Sebastian Böttcher, Marco Herling, Jurgen Kuball, Marietta Truger, Torsten Haferlach, Jan Krönke, Uwe Platzbecker, Klaus Metzeler, Ulrike Koehl, Vladan Vucinic, Zsolt Sebestyen, Kristin Reiche, Maximillian Merz
Journal: Blood
Blood (2025) 146 (Supplement 1): 690.
https://doi.org/10.1182/blood-2025-690
Published: 2025
Journal Articles

Sarcopenia and body composition predict survival and reveal immunometabolic dysfunction via single-cell profiling in anti-BCMA CAR T-treated myeloma

Free
Thomas Wiemers, Michael Rade, Nora Grieb, Maximilian Ferle, Tihomir Dermendzhiev, David Fandrei, Patrick Born, Sabine Seiffert, Anja Grahnert, Maik Friedrich, Ronny Baber, Markus Kreuz, Klaus Metzeler, Marco Herling, Carmen Herling, Madlen Jentzsch, Georg-Nikolaus Franke, Andreas Boldt, Ulrike Koehl, Kristin Reiche, Timm Denecke, Urvi Shah, Uwe Platzbecker, Vladan Vucinic, Hans-Jonas Meyer, Maximilian Merz
Journal: Blood
Blood (2025) 146 (Supplement 1): 7676.
https://doi.org/10.1182/blood-2025-7676
Published: 2025
Journal Articles

Impact of bridging therapy on efficacy of CD19 CAR T cell therapy in diffuse-large B cell lymphoma: Histology and the choice of drug matter

Free
Julia Katharina Scholz, Evgenii Shumilov, Valeria Carobin, Viktoria Blumenberg, Jonas Wisskirchen, Sabine Seiffert, Philipp Nakov, Guranda Chitadze, Andreas Riedel, Nico Gagelmann, Tobias A.W. Holderried, Christian Schultze-Florey, Monika Fischer, Dennis Harrer, Kerstin Schaefer-Eckart, Soraya Kharboutli, Dimitrios Mougiakakos, Stefan Knop, Leo Hansmann, Peter Dreger, Christian Koenecke, Francis Ayuk, Wolfgang Bethge, Christiane Pott, Vladan Vucinic, Eva-Maria Wagner Drouet, Marion Subklewe, Georg Lenz, Simon Voelkl, Andreas Mackensen, Fabian Müller
Journal: Blood
Blood (2025) 146 (Supplement 1): 1949.
https://doi.org/10.1182/blood-2025-1949
Published: 2025
Journal Articles

Persistent Thrombocytopenia and Neutropenia Are Associated with Increased Mortality in Patients Treated with Anti-BCMA CAR T Cells for Relapsed/Refractory Multiple Myeloma

Free
Thomas C Wiemers, David Fandrei, Sabine Seiffert, Michael Rade, Susanne Rieprecht, Patrick Born, Markus Kreuz, Luise Fischer, Ronny Baber, Song Yau Wang, Enrica Bach, Sandra Hoffmann, Klaus H Metzeler, Marco Herling, Madlen Jentzsch, Georg-Nikolaus Franke, Ulrike Köhl, Maik Friedrich, Andreas Boldt, Kristin Reiche, Uwe Platzbecker, Vladan Vucinic, Maximilian Merz
Journal: Blood
Blood (2024) 144 (Supplement 1): 7095.
https://doi.org/10.1182/blood-2024-202101
Published: 2024
Journal Articles

Prognostic Value of Baseline and Early Response FDG-PET/CT Combined with Cellular Dynamics in Patients with Refractory and Relapsed Mantle Cell Lymphoma (MCL) Undergoing Chimeric Antigen Receptor (CAR)-T Cell Therapy

Free
Simon M Krauß, Sabine Seiffert, Carmen Perez Fernandez, Thomas Walter Georgi, Janine Kirchberg, Enrica Bach, Mandy Brueckner, Madlen Jentzsch, Carmen Herling, Maximilian Merz, Klaus H Metzeler, Marco Herling, Georg-Nikolaus Franke, Andreas Boldt, Solveig Tiepolt, Regine Kluge, Ulrike Koehl, Timm Denecke, Osama Sabri, Ulrich Sack, Uwe Platzbecker, Lars Kurch, Vladan Vucinic
Journal: Blood
Blood (2024) 144 (Supplement 1): 6343.
https://doi.org/10.1182/blood-2024-206686
Published: 2024
Journal Articles

The Differences between Ide-Cel and Cilta-Cel in Relapsed Myeloma at Single Cell Resolution

Free
David Fandrei, Michael Rade, Markus Kreuz, Luise Fischer, Patrick Born, Sabine Seiffert, Andreas Boldt, Jonathan Scolnick, Lakshmi Venkatraman, Stacy Xu, Ronny Baber, Song Yau Wang, Enrica Bach, Sandra Hoffmann, Klaus H Metzeler, Marco Herling, Madlen Jentzsch, Georg-Nikolaus Franke, Ulrike Köhl, Uwe Platzbecker, Vladan Vucinic, Kristin Reiche, Maximilian Merz
Journal: Blood
Blood (2024) 144 (Supplement 1): 1877.
https://doi.org/10.1182/blood-2024-210746
Published: 2024
Journal Articles

Cellular Dynamics Following CAR T Cell Therapy Are Associated with Response, Resistance and Cytokine Release Syndrome in Relapsed/Refractory Multiple Myeloma

Free
Luise Fischer, Patrick Born, Ronald Weiss, Nora Grieb, Sabine Seiffert, Andreas Boldt, Stephan Fricke, Paul Franz, Christina Kloetzer, Simone Heyn, Ronny Baber, Song-Yau Wang, Enrica Bach, Sandra Hoffmann, Jule Ussmann, Janine Kirchberg, Klaus H Metzeler, Marco Herling, Madlen Jentzsch, Georg-Nikolaus Franke, Ulrich Sack, Kristin Reiche, Ulrike Koehl, Uwe Platzbecker, Vladan Vucinic, Maximilian Merz
Journal: Blood
Blood (2023) 142 (Supplement 1): 1008.
https://doi.org/10.1182/blood-2023-188367
Published: 2023