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Matthias Schlesner
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Journal Articles

Multi-Omics Profiling of JMML HSPCs Reveals Onco-Fetal Reprogramming and Identifies Novel Prognostic Biomarkers and Therapeutic Targets in High-Risk JMML

Mark Hartmann, Ling Hai, Joschka Hey, Maximilian Schönung, Valentin Maurer, Jovana Rajak, Sina Staeble, Jens Langstein, Katharina Bauer, Mariam Hakobyan, Laura Jardine, Sheila Bohler, Dominik Vonficht, Abdul-Habib Maag, Dirk Lebrecht, Kathrin M. Bernt, Roland Roelz, Tobias Boch, Eleonora Khabirova, Pavlo Lutsik, Oliver Stegle, Simon Haas, Muzlifah Haniffa, Sam Behjati, Jan-Philipp Mallm, Christian Buske, Stefan Fröhling, Christoph Plass, Charlotte M. Niemeyer, Christian Flotho, Marc Jan Bonder, Miriam Erlacher, Matthias Schlesner, Daniel B. Lipka
Journal: Blood
Blood (2022) 140 (Supplement 1): 8729–8730.
https://doi.org/10.1182/blood-2022-162224
Published: 2022
Journal Articles

Increased Frequency of Mosaic Chromosomal Alterations in Peripheral Blood Samples of Sub-Saharan African Children with Endemic Burkitt Lymphoma

Weiyin Zhou, Anja Pfaus, Martin Ogwang, Wen Luo, Patrick Kerchan, Steven Reynolds, Constance N Tenge, Pamela A Were, Robert T Kuremu, Walter N Wekesa, Nestory Masalu, Esther Kawira, Tobias Kinyera, Isaac Otim, Ismail D Legason, Hadijah Nabalende, Leona W Ayers, Kishor Bhatia, James J Goedert, Nathan Cole, Belynda Hicks, Kristine Jones, Michael Hummel, Matthias Schlesner, George Chagaluka, Nora Mutalima, Eric Borgstein, George N Liomba, Steve Kamiza, Nyengo Mkandawire, Collins Mitambo, Elizabeth Molyneux, Robert Newton, Selina Glaser, Michelle Manning, Amy Hutchinson, Ann W Hsing, Yao Tettey, Andrew Anthony Adjei, Stephen J. Chanock, Reiner Siebert, Meredith Yeager, Mitchell Machiela, Sam M. Mbulaiteye
Journal: Blood
Blood (2022) 140 (Supplement 1): 9240–9241.
https://doi.org/10.1182/blood-2022-169500
Published: 2022
Journal Articles

A Novel FBXO45-Gef-H1 Axis Controls Oncogenic Signaling in B-Cell Lymphoma

Anagh Anant Sahasrabuddhe, Xiaofei Chen, Kaiyu Ma, Rui Wu, Richa Kapoor, Rishi Raj Chhipa, Xiao Zhang, Ozlem Onder, Joel Wilmore, Brian T. Gaudette, Vinodh Pillai, Marilyn M. Li, Joon-Young Ahn, Fuzon Chung, Philippe Szankasi, Venkatesha Basrur, Kevin P Conlon, Nathanael G. Bailey, Cory M Hogaboam, Robert Rottapel, Junhyong Kim, Cristina Lopez, Julian Seufert, Matthias Schlesner, Reiner Siebert, Michael P Cancro, David Allman, Michele Pagano, Louis M. Staudt, Megan S. Lim, Kojo S. J. Elenitoba-Johnson
Journal: Blood
Blood (2021) 138 (Supplement 1): 711.
https://doi.org/10.1182/blood-2021-151245
Published: 2021
Journal Articles

Systematic Evaluation of Somatic Cis -Regulatory Mutations in Follicular Lymphoma

Firat Uyulur, MSc, Findlay Bewicke-Copley, PhD MSc, BSc, Chinedu Anthony Anene, PhD, Matthias Schlesner, PhD, Icgc MMML-Seq Project, Reiner Siebert, Prof. Dr. MD, Jessica Okosun, MD PhD, Jude Fitzgibbon, PhD, Jun Wang, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 26–27.
https://doi.org/10.1182/blood-2020-142623
Published: 2020
Journal Articles

Comprehensive Comparison of Early Relapse and End-Stage Relapsed Refractory Multiple Myeloma

Alexandra M Poos, PhD, Nicola Giesen, MD, Calogerina Catalano, PhD, Nagarajan Paramasivam, PhD, Daniel Huebschmann, MDPhD, Lukas John, Anja Baumann, Jason Hochhaus, Carsten Mueller-Tidow, MD, Sandra Sauer, MD, Stefanie Huhn, PhD, Matthias Schlesner, PhD, Benedikt Brors, PhD, Hartmut Goldschmidt, MD, Marc S. Raab, MD, Niels Weinhold, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 1.
https://doi.org/10.1182/blood-2020-141611
Published: 2020
Journal Articles

Characterization of Rare Germline Variants in Familial Multiple Myeloma

Calogerina Catalano, PhD, Joanna Blocka, MD, Stefanie Huhn, PhD, Nagarajan Paramasivam, PhD, Matthias Schlesner, PhD, Niels Weinhold, PhD, Rolf Sijmons, MD, Christian Langer, MD, Klaus Preuss, PhD, Brian G.M. Durie, MD, Björn Nilsson, MD PhD, Hartmut Goldschmidt, MD, Obul Reddy Bandapalli, PhD, Kari Hemminki, MD PhD, Asta Försti, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 45–46.
https://doi.org/10.1182/blood-2020-142253
Published: 2020
Journal Articles

Deconvolution of Hematopoietic Commitment Decisions By Genome-Wide Analysis of Progressive DNA Methylation Changes

Sina Staeble, MSc, Stephen Kraemer, MSc, Jens Langstein, MSc, Ruzhica Bogeska, PhD, Mark Hartmann, PhD, Maximilian Schoenung, MSc, Melinda Czeh, PhD, Julia Knoch, Natasha Anstee, PhD, Simon Haas, PhD, Abdelrahman Mahmoud, MSc, Julius Graesel, MSc, Daniel Huebschmann, MD PhD, Lars Feuerbach, PhD, Weichenhan Dieter, PhD, Benedikt Brors, PhD, Karsten Rippe, PhD, Jan-Philipp Mallm, PhD, Frank Rosenbauer, PhD, Christoph Plass, PhD, Matthias Schlesner, PhD, Michael D. Milsom, PhD, Daniel B. Lipka, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1179.
https://doi.org/10.1182/blood-2019-124429
Published: 2019
Journal Articles

The mutational landscape of Burkitt-like lymphoma with 11q aberration is distinct from that of Burkitt lymphoma

Brief Report
Rabea Wagener, Julian Seufert, Francesco Raimondi, Susanne Bens, Kortine Kleinheinz, Inga Nagel, Janine Altmüller, Holger Thiele, Daniel Hübschmann, Christian W. Kohler, Peter Nürnberg, Rex Au-Yeung, Birgit Burkhardt, Heike Horn, Lorenzo Leoncini, Elaine S. Jaffe, German Ott, Grzegorz Rymkiewicz, Matthias Schlesner, Robert B. Russell, Wolfram Klapper, Reiner Siebert
Journal: Blood
Blood (2019) 133 (9): 962–966.
https://doi.org/10.1182/blood-2018-07-864025
Published: 2019
Includes: Supplemental data
Journal Articles

IG- MYC + neoplasms with precursor B-cell phenotype are molecularly distinct from Burkitt lymphomas

Brief Report
Rabea Wagener, Cristina López, Kortine Kleinheinz, Julia Bausinger, Sietse M. Aukema, Inga Nagel, Umut H. Toprak, Julian Seufert, Janine Altmüller, Holger Thiele, Christof Schneider, Julia Kolarova, Jeongbin Park, Daniel Hübschmann, Eva M. Murga Penas, Hans G. Drexler, Andishe Attarbaschi, Randi Hovland, Eigil Kjeldsen, Michael Kneba, Udo Kontny, Laurence de Leval, Peter Nürnberg, Ilske Oschlies, David Oscier, Brigitte Schlegelberger, Stephan Stilgenbauer, Wilhelm Wössmann, Matthias Schlesner, Birgit Burkhardt, Wolfram Klapper, Elaine S. Jaffe, Ralf Küppers, Reiner Siebert
Journal: Blood
Blood (2018) 132 (21): 2280–2285.
https://doi.org/10.1182/blood-2018-03-842088
Published: 2018
Includes: Supplemental data
Journal Articles

Comprehensive Genomic Characterization of Refractory Multiple Myeloma Reveals a Complex Mutational and Structural Landscape Associated with Drug Resistance

Nicola Lehners, MD, Umut H Toprak, Jing Xu, Nagarajan Paramasivam, Daniel Hübschmann, Martina Fröhlich, Nur H Md Hanafiah, Sadaf Mughal, Elias K Mai, MD, Anna Jauch, Jens Hillengass, MD, Roland Eils, Carsten Müller-Tidow, Benedikt Brors, Hartmut Goldschmidt, MD, Matthias Schlesner, Marc S Raab, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 266.
https://doi.org/10.1182/blood.V130.Suppl_1.266.266
Published: 2017
Journal Articles

B-cell–specific conditional expression of Myd88 p.L252P leads to the development of diffuse large B-cell lymphoma in mice

Gero Knittel, Paul Liedgens, Darya Korovkina, Jens M. Seeger, Yussor Al-Baldawi, Mona Al-Maarri, Christian Fritz, Katerina Vlantis, Svetlana Bezhanova, Andreas H. Scheel, Olaf-Oliver Wolz, Maurice Reimann, Peter Möller, Cristina López, Matthias Schlesner, Philipp Lohneis, Alexander N. R. Weber, Lorenz Trümper, German International Cancer Genome Consortium Molecular Mechanisms in Malignant Lymphoma by Sequencing Project Consortium, Louis M. Staudt, Monika Ortmann, Manolis Pasparakis, Reiner Siebert, Clemens A. Schmitt, Andreas R. Klatt, F. Thomas Wunderlich, Stephan C. Schäfer, Thorsten Persigehl, Manuel Montesinos-Rongen, Margarete Odenthal, Reinhard Büttner, Lukas P. Frenzel, Hamid Kashkar, H. Christian Reinhardt
Journal: Blood
Blood (2016) 127 (22): 2732–2741.
https://doi.org/10.1182/blood-2015-11-684183
Published: 2016
Includes: Supplemental data
Journal Articles

A recurrent 11q aberration pattern characterizes a subset of MYC -negative high-grade B-cell lymphomas resembling Burkitt lymphoma

Itziar Salaverria, Idoia Martin-Guerrero, Rabea Wagener, Markus Kreuz, Christian W. Kohler, Julia Richter, Barbara Pienkowska-Grela, Patrick Adam, Birgit Burkhardt, Alexander Claviez, Christine Damm-Welk, Hans G. Drexler, Michael Hummel, Elaine S. Jaffe, Ralf Küppers, Christine Lefebvre, Jasmin Lisfeld, Markus Löffler, Roderick A. F. Macleod, Inga Nagel, Ilske Oschlies, Maciej Rosolowski, Robert B. Russell, Grzegorz Rymkiewicz, Detlev Schindler, Matthias Schlesner, René Scholtysik, Carsten Schwaenen, Rainer Spang, Monika Szczepanowski, Lorenz Trümper, Inga Vater, Swen Wessendorf, Wolfram Klapper, Reiner Siebert
Journal: Blood
Blood (2014) 123 (8): 1187–1198.
https://doi.org/10.1182/blood-2013-06-507996
Published: 2014
Includes: Supplemental data
Journal Articles

In-Depth miRNA Profiling Of Germinal Center Derived B-Cell Lymphomas By Next Generation Sequencing: A Report From The German Icgc-Mmml-Seq Project

Jessica I Hoell, MD, Kebria Hezaveh, Stephan Bernhart, Steve Hoffmann, David Langenberger, Matthias Schlesner, Peter Stadler, Vera Binder, Dido Lenze, Reiner Siebert, MD, Michael Hummel, PhD, Arndt Borkhardt, MD
Journal: Blood
Blood (2013) 122 (21): 2500.
https://doi.org/10.1182/blood.V122.21.2500.2500
Published: 2013
Journal Articles

Clonal Evolution In Patients With Chronic Lymphocytic Leukemia (CLL) Developing Resistance To BTK Inhibition

Jan A. Burger, MD, PhD, Dan Landau, M.D., Julia Hoellenriegel, Carrie Sougnez, Matthias Schlesner, Naveed Ishaque, Benedikt Brors, Michael J. Keating, MD, William G. Wierda, MD, Kristian Cibulskis, Hagop M. Kantarjian, MD, Susan M. O'Brien, MD, Donna S. Neuberg, ScD, Thorsten Zenz, MD, Gad Getz, Catherine J Wu, MD
Journal: Blood
Blood (2013) 122 (21): 866.
https://doi.org/10.1182/blood.V122.21.866.866
Published: 2013