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Journal Articles

Dimethyl fumarate induces ferroptosis and impairs NF-κB/STAT3 signaling in DLBCL

Anja Schmitt, Wendan Xu, Philip Bucher, Melanie Grimm, Martina Konantz, Heike Horn, Myroslav Zapukhlyak, Philipp Berning, Marc Brändle, Mohamed-Ali Jarboui, Caroline Schönfeld, Karsten Boldt, Andreas Rosenwald, German Ott, Michael Grau, Pavel Klener, Petra Vockova, Claudia Lengerke, Georg Lenz, Klaus Schulze-Osthoff, Stephan Hailfinger
Journal: Blood
Blood (2021) 138 (10): 871–884.
https://doi.org/10.1182/blood.2020009404
Published: 2021
Includes: Supplemental data
Journal Articles

Adding Etoposide to R-CHOP (R-CHOEP) Does Not Significantly Increase the Risk of Secondary Neoplasms in Patients with Aggressive B-Cell Lymphoma - Results from Randomized Phase 3 Trials of the German Lymphoma Alliance (GLA)

Fabian Frontzek, MD, Marita Ziepert, PhD, Maike Nickelsen, Bettina Altmann, PhD, Bertram Glass, Mathias Haenel, MD, Lorenz Truemper, MD PhD, Gerhard Held, MD, Martin Bentz, MD, Peter Borchmann, MD, Martin Dreyling, MD, Andreas Viardot, Professor Dr, Frank P. Kroschinsky, MDMBA, Bernd Metzner, MDPhD, Annette M. Staiger, PhD, Heike Horn, PhD, German Ott, MD, Andreas Rosenwald, MD, Markus Loeffler, MD, Georg Lenz, Norbert Schmitz, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 5–6.
https://doi.org/10.1182/blood-2020-138412
Published: 2020
Journal Articles

Localized- and advanced-stage follicular lymphomas differ in their gene expression profiles

Annette M. Staiger, Eva Hoster, Vindi Jurinovic, Stefan Winter, Ellen Leich, Claudia Kalla, Peter Möller, Heinz-Wolfram Bernd, Alfred C. Feller, Karoline Koch, Wolfram Klapper, Harald Stein, Martin-Leo Hansmann, Sylvia Hartmann, Martin Dreyling, Oliver Weigert, Wolfgang Hiddemann, Klaus Herfarth, Andreas Rosenwald, Marianne Engelhard, German Ott, Heike Horn
Journal: Blood
Blood (2020) 135 (3): 181–190.
https://doi.org/10.1182/blood.2019000560
Published: 2020
Includes: Supplemental data
Journal Articles

Conventional Immunochemotherapy (R-CHOEP) Vs High-Dose Immunochemotherapy (R-MegaCHOEP) in Younger Patients with High-Risk Aggressive B-Cell Lymphoma: 10-Year Long-Term Follow-up of a German Lymphoma Alliance (GLA) Study

Fabian Frontzek, MD, Marita Ziepert, PhD, Maike Nickelsen, Bettina Altmann, PhD, Bertram Glass, Mathias Hänel, MD, Lorenz Truemper, MD, Gerhard Held, MD, Martin Bentz, MD, Peter Borchmann, MD, Martin H. Dreyling, MD PhD, Andreas Viardot, MD PhD, Frank P. Kroschinsky, MDMBA, Bernd Metzner, MD PhD, Annette M. Staiger, PhD, Heike Horn, PhD, German Ott, MD, Andreas Rosenwald, MD, Markus Loeffler, MD, Georg Lenz, MD, Norbert Schmitz, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1589.
https://doi.org/10.1182/blood-2019-123637
Published: 2019
Journal Articles

The mutational landscape of Burkitt-like lymphoma with 11q aberration is distinct from that of Burkitt lymphoma

Brief Report
Rabea Wagener, Julian Seufert, Francesco Raimondi, Susanne Bens, Kortine Kleinheinz, Inga Nagel, Janine Altmüller, Holger Thiele, Daniel Hübschmann, Christian W. Kohler, Peter Nürnberg, Rex Au-Yeung, Birgit Burkhardt, Heike Horn, Lorenzo Leoncini, Elaine S. Jaffe, German Ott, Grzegorz Rymkiewicz, Matthias Schlesner, Robert B. Russell, Wolfram Klapper, Reiner Siebert
Journal: Blood
Blood (2019) 133 (9): 962–966.
https://doi.org/10.1182/blood-2018-07-864025
Published: 2019
Includes: Supplemental data
Journal Articles

Clinicogenetic Risk Models in Patients Randomized to Receive Consolidative Autologous Stem-Cell Transplantation after Frontline R-CHOP for Advanced Follicular Lymphoma: An Analysis from the GLSG2000 Trial

Stefan Alig, MD, Alessandro Pastore, Vindi Jurinovic, Sarah Häbe, Deepak Bararia, PhD, Verena Passerini, PhD, William Keay, Johannes Hellmuth, Andreas Rosenwald, Wolfram Klapper, MD, Harald Stein, MD PhD Dr. h.c., Alfred Feller, German Ott, MD, Annette M. Staiger, PhD, Heike Horn, Martin-Leo Hansmann, Christiane Pott, Roswitha Forstpointner, Wolf-Karsten Hofmann, Norbert Schmitz, MD, Georg Hess, Michael Unterhalt, Martin H. Dreyling, MD PhD, Anna-Katharina Zoellner, Christian Schmidt, MD, Eva Hoster, Wolfgang Hiddemann, Oliver Weigert, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4096.
https://doi.org/10.1182/blood-2018-99-118000
Published: 2018
Journal Articles

A New Stromal Signature Applicable to Formalin-Fixed Paraffin-Embedded Tissues Identifies Patients at Risk in Prospective Clinical Trials of the German High-Grade Non-Hodgkin Lymphoma Study Group

Annette M. Staiger, PhD, Michael Altenbuchinger, PhD, Marita Ziepert, PhD, Christian Kohler, PhD, Heike Horn, Michael Huttner, Katrin Huettl, MD, Wolfram Klapper, MD, Monika Szczepanowski, PhD, Julia Richter, PhD, Andreas Rosenwald, Harald Stein, MD PhD Dr. h.c., Alfred Feller, Peter Moeller, MD, Martin-Leo Hansmann, Markus Loeffler, MD, Viola Poeschel, MD, Gerhard Held, MD, Lorenz Truemper, MD, German Ott, MD, Rainer Spang, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 343.
https://doi.org/10.1182/blood-2018-99-112450
Published: 2018
Journal Articles

High-grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements with diffuse large B-cell lymphoma morphology

Brief Report
David W. Scott, Rebecca L. King, Annette M. Staiger, Susana Ben-Neriah, Aixiang Jiang, Heike Horn, Anja Mottok, Pedro Farinha, Graham W. Slack, Daisuke Ennishi, Norbert Schmitz, Michael Pfreundschuh, Grzegorz S. Nowakowski, Brad S. Kahl, Joseph M. Connors, Randy D. Gascoyne, German Ott, William R. Macon, Andreas Rosenwald
Journal: Blood
Blood (2018) 131 (18): 2060–2064.
https://doi.org/10.1182/blood-2017-12-820605
Published: 2018
Includes: Supplemental data
Journal Articles

FOXP1 expression is a prognostic biomarker in follicular lymphoma treated with rituximab and chemotherapy

Anja Mottok, Vindi Jurinovic, Pedro Farinha, Andreas Rosenwald, Ellen Leich, German Ott, Heike Horn, Wolfram Klapper, Michael Boesl, Wolfgang Hiddemann, Christian Steidl, Joseph M. Connors, Laurie H. Sehn, Randy D. Gascoyne, Eva Hoster, Oliver Weigert, Robert Kridel
Journal: Blood
Blood (2018) 131 (2): 226–235.
https://doi.org/10.1182/blood-2017-08-799080
Published: 2018
Includes: Supplemental data
Journal Articles

Genetically-Defined Diffuse Large B-Cell Lymphoma Subsets Arise By Distinct Pathogenetic Mechanisms and Predict Outcome

Bjoern Chapuy, MD PhD, Chip Stewart, PhD, Andrew Dunford, MS, Jaegil Kim, PhD, Atanas Kamburow, PhD, Robert A. Redd, MS, Michael Lawrence, PhD, Margaretha G.M. Roemer, MSc, Amy Li, Marita Ziepert, PhD, Annette M. Staiger, PhD, Jeremiah Wala, Matthew D. Ducar, MS, Ignaty Leshchiner, PhD, Esther Rheinbay, PhD, Amaro Taylor-Weiner, BS, Caroline Coughlin, BS, Julian Hess, Chandra Pedamallu, Dimitri Livitz, Daniel Rosebrock, Mara Rosenberg, Adam Tracy, Heike Horn, Paul van Hummelen, Andrew L Feldman, MD, Brian K Link, MD, Anne J Novak, PhD, James R. Cerhan, MD PhD, Thomas M Habermann, MD, Reiner Siebert, PhD, Andreas Rosenwald, Aaron R. Thorner, PhD, Matthew Meyerson, MDPhD, Todd R. Golub, MD, Rameen Beroukhim, Gerald Wulf, MD, German Ott, MD, Scott J. Rodig, MDPhD, Stefano Monti, PhD, Donna S. Neuberg, ScD, Markus Loeffler, MD, Michael Pfreundschuh, MD, Lorenz Trümper, MD, Gad Getz, PhD, Margaret A. Shipp, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 38.
https://doi.org/10.1182/blood.V130.Suppl_1.38.38
Published: 2017
Journal Articles

FOXP1 Expression Is a Prognostic Biomarker in Follicular Lymphoma Treated with Immunochemotherapy and Is Associated with Distinct Molecular Features

Robert Kridel, Vindi Jurinovic, Pedro Farinha, Andreas Rosenwald, Ellen Leich, German Ott, MD, Heike Horn, Wolfram Klapper, MD, Michael Boesl, Wolfgang Hiddemann, Christian Steidl, MD, Joseph M Connors, MD, Laurie H. Sehn, MDMPH, Randy D. Gascoyne, MD, Eva Hoster, Oliver Weigert, Anja Mottok
Journal: Blood
Blood (2017) 130 (Supplement 1): 2748.
https://doi.org/10.1182/blood.V130.Suppl_1.2748.2748
Published: 2017
Journal Articles

The Clinical Impact of the Cell-of-Origin Classification and the MYC+/BCL2+ Double Expresser Status in DLBCL Treated within Prospective Clinical Trials of the Dshnhl

Annette M. Staiger, PhD, Marita Ziepert, Heike Horn, PhD, David W. Scott, Thomas F. E. Barth, MD, Heinz-Wolfram Bernd, MD, Alfred C. Feller, MD, Wolfram Klapper, MD, Michael Hummel, Harald Stein, MD PhD, Dido Lenze, Martin-Leo Hansmann, MD, Sylvia Hartmann, MD, Peter Moeller, MD, Sergio Cogliatti, MD, Georg Lenz, MD, Lorenz H. Truemper, MD PhD, Markus Loeffler, MD PhD, Norbert Schmitz, MD, PhD, Michael Pfreundschuh, MD, Andreas Rosenwald, MD, German Ott
Journal: Blood
Blood (2016) 128 (22): 151.
https://doi.org/10.1182/blood.V128.22.151.151
Published: 2016
Journal Articles

Clinicogenetic risk models predict early progression of follicular lymphoma after first-line immunochemotherapy

Clinical Trials & Observations
Vindi Jurinovic, Robert Kridel, Annette M. Staiger, Monika Szczepanowski, Heike Horn, Martin H. Dreyling, Andreas Rosenwald, German Ott, Wolfram Klapper, Andrew D. Zelenetz, Paul M. Barr, Jonathan W. Friedberg, Stephen Ansell, Laurie H. Sehn, Joseph M. Connors, Randy D. Gascoyne, Wolfgang Hiddemann, Michael Unterhalt, David M. Weinstock, Oliver Weigert
Journal: Blood
Blood (2016) 128 (8): 1112–1120.
https://doi.org/10.1182/blood-2016-05-717355
Published: 2016
Includes: Supplemental data
Journal Articles

Comprehensive Analyses of Genetic Features Identify Coordinate Signatures in Diffuse Large B-Cell Lymphoma

Bjoern Chapuy, MDPhD, Andrew J Dunford, BS, Chip Stewart, PhD, Atanas Kamburov, PhD, Jaegil Kim, PhD, Margaretha GM Roemer, MS, Marita Ziepert, PhD, Amy Jiayue Li, Mike Lawrence, PhD, Julian Hess, BS, Mara Rosenburg, BS, Amaro N Taylor-Weiner, BS, Robert A Redd, MS, Heike Horn, PhD, Anne Novak, PhD, James R Cerhan, MDPhD, Thomas M Haberman, MD, Andrew L Feldman, MD, Brian K Link, MD, Todd R Golub, MD, Donna S Neuberg, ScD, German Ott, MD, Reiner Siebert, MD, Andreas Rosenwald, MD, Gerald G Wulf, MD, Stefano Monti, PhD, Scott J Rodig, MD PhD, Markus Löffler, PhD, Michael Pfreundschuh, MD, Lorenz Trümper, MD, Gad Getz, PhD, Margaret A. Shipp, MD
Journal: Blood
Blood (2015) 126 (23): 3922.
https://doi.org/10.1182/blood.V126.23.3922.3922
Published: 2015
Journal Articles

A Clinicogenetic Risk Model (m7-FLIPI) Prospectively Identifies One-Half of Patients with Early Disease Progression of Follicular Lymphoma after First-Line Immunochemotherapy

Jurinovic Vindi, Dipl Math, Robert Kridel, MD MPH, Annette M Staiger, MSc, Monika Szczepanowski, PhD, Heike Horn, PhD, Martin H. Dreyling, MD PhD, Andreas Rosenwald, MD, German Ott, MD, Wolfram Klapper, MD, Andrew D. Zelenetz, MD PhD, Jonathan W. Friedberg, MD MMSc, Stephen Ansell, MD PhD, Laurie H. Sehn, Joseph M Connors, MD, Randy D. Gascoyne, David M. Weinstock, Wolfgang Hiddemann, MD PhD, Michael Unterhalt, PhD, Eva Hoster, PhD, Oliver Weigert, MD
Journal: Blood
Blood (2015) 126 (23): 333.
https://doi.org/10.1182/blood.V126.23.333.333
Published: 2015
Journal Articles

The Prognostic Impact Of Gene Rearrangements and Protein Expression Of MYC, BCL2 and BCL6 In Young High-Risk Patients With DLBCL

Heike Horn, Marita Ziepert, Thomas F.E. Barth, Heinz-Wolfram Bernd, Martin Wartenberg, Alfred C. Feller, Wolfram Klapper, Michael Hummel, PhD, Harald Stein, MD, Dido Lenze, Sylvia Hartmann, Martin-Leo Hansmann, Peter Möller, Sergio Cogliatti, Michael Pfreundschuh, Lorenz Trümper, Markus Löffler, MD, German Ott, MD, Norbert Schmitz, Andreas Rosenwald
Journal: Blood
Blood (2013) 122 (21): 4262.
https://doi.org/10.1182/blood.V122.21.4262.4262
Published: 2013
Journal Articles

The Phenotype High Noxa mRNA/Low NOXA Protein Levels Constitutes a Critical Achilles Heel Of Mantle Cell Lymphoma (MCL) Cells

Michael A. Dengler, Andrea Weilbacher, Matthias Gutekunst, Annette M. Staiger, Heike Horn, German Ott, MD, Heiko van der Kuip, Walter E. Aulitzky
Journal: Blood
Blood (2013) 122 (21): 644.
https://doi.org/10.1182/blood.V122.21.644.644
Published: 2013
Journal Articles

MYC status in concert with BCL2 and BCL6 expression predicts outcome in diffuse large B-cell lymphoma

Heike Horn, Marita Ziepert, Claudia Becher, Thomas F. E. Barth, Heinz-Wolfram Bernd, Alfred C. Feller, Wolfram Klapper, Michael Hummel, Harald Stein, Martin-Leo Hansmann, Christopher Schmelter, Peter Möller, Sergio Cogliatti, Michael Pfreundschuh, Norbert Schmitz, Lorenz Trümper, Reiner Siebert, Markus Loeffler, Andreas Rosenwald, German Ott
Journal: Blood
Blood (2013) 121 (12): 2253–2263.
https://doi.org/10.1182/blood-2012-06-435842
Published: 2013
Journal Articles

TP53 Mutation Is an Independent Predictor of Poor Survival in Untreated Patients with CD20 + Aggressive B-Cell Lymphoma: Analysis within the Ricover-60 Trial

Thorsten Zenz, MD, Markus Kreuz, Doris Winter, Hanne Helfrich, Maxi Fuge, Heike Horn, MD, Julia Richter, PhD, Reiner Siebert, Lorenz Truemper, MD, Norbert Schmitz, MD, Markus Loeffler, Wolfram Klapper, Andreas Rosenwald, MD, Hartmut Döhner, MD, Michael Pfreundschuh, MD, German Ott, MD, Stephan Stilgenbauer, MD
Journal: Blood
Blood (2012) 120 (21): 546.
https://doi.org/10.1182/blood.V120.21.546.546
Published: 2012
Journal Articles

Cyclin D1 Over-Expressing Mantle Cell Lymphoma Cells Are Hypersensitive to Inhibition of Fatty Acid Synthase (FASN)

Michael A. Dengler, Matthias Gutekunst, Stephanie Kopacz, Heike Horn, Ute Hofmann, Matthias Schwab, German Ott, MD, Heiko van der Kuip, Walter E. Aulitzky
Journal: Blood
Blood (2011) 118 (21): 1656.
https://doi.org/10.1182/blood.V118.21.1656.1656
Published: 2011