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Annette M. Staiger
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Journal Articles

Lymphomagenic Roles of MYC, E2F and Mir-150-5p in Plasmablastic Lymphoma: Therapeutic and Prognostic Implications

Miriam Verdú Bou, Maria Joao Baptista, Aleix Mendez Lopez, Gustavo Tapia, Marcelo Lima Ribeiro, Gaël Roué, Jose Luis Mate, Pau Abrisqueta, Mariana Bastos-Oreiro, Miguel Alcoceba, Eva González Barca, Fina Climent, Antonio Salar, Juan-Manuel Sancho, Fabian Frontzek, Annette M. Staiger, German Ott, Manuel Castro De Moura, Georg Lenz, Jose Tomas Navarro
Journal: Blood
Blood (2022) 140 (Supplement 1): 9266–9268.
https://doi.org/10.1182/blood-2022-168552
Published: 2022
Journal Articles

Adding Etoposide to R-CHOP (R-CHOEP) Does Not Significantly Increase the Risk of Secondary Neoplasms in Patients with Aggressive B-Cell Lymphoma - Results from Randomized Phase 3 Trials of the German Lymphoma Alliance (GLA)

Fabian Frontzek, MD, Marita Ziepert, PhD, Maike Nickelsen, Bettina Altmann, PhD, Bertram Glass, Mathias Haenel, MD, Lorenz Truemper, MD PhD, Gerhard Held, MD, Martin Bentz, MD, Peter Borchmann, MD, Martin Dreyling, MD, Andreas Viardot, Professor Dr, Frank P. Kroschinsky, MDMBA, Bernd Metzner, MDPhD, Annette M. Staiger, PhD, Heike Horn, PhD, German Ott, MD, Andreas Rosenwald, MD, Markus Loeffler, MD, Georg Lenz, Norbert Schmitz, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 5–6.
https://doi.org/10.1182/blood-2020-138412
Published: 2020
Journal Articles

Localized- and advanced-stage follicular lymphomas differ in their gene expression profiles

Annette M. Staiger, Eva Hoster, Vindi Jurinovic, Stefan Winter, Ellen Leich, Claudia Kalla, Peter Möller, Heinz-Wolfram Bernd, Alfred C. Feller, Karoline Koch, Wolfram Klapper, Harald Stein, Martin-Leo Hansmann, Sylvia Hartmann, Martin Dreyling, Oliver Weigert, Wolfgang Hiddemann, Klaus Herfarth, Andreas Rosenwald, Marianne Engelhard, German Ott, Heike Horn
Journal: Blood
Blood (2020) 135 (3): 181–190.
https://doi.org/10.1182/blood.2019000560
Published: 2020
Includes: Supplemental data
Journal Articles

Conventional Immunochemotherapy (R-CHOEP) Vs High-Dose Immunochemotherapy (R-MegaCHOEP) in Younger Patients with High-Risk Aggressive B-Cell Lymphoma: 10-Year Long-Term Follow-up of a German Lymphoma Alliance (GLA) Study

Fabian Frontzek, MD, Marita Ziepert, PhD, Maike Nickelsen, Bettina Altmann, PhD, Bertram Glass, Mathias Hänel, MD, Lorenz Truemper, MD, Gerhard Held, MD, Martin Bentz, MD, Peter Borchmann, MD, Martin H. Dreyling, MD PhD, Andreas Viardot, MD PhD, Frank P. Kroschinsky, MDMBA, Bernd Metzner, MD PhD, Annette M. Staiger, PhD, Heike Horn, PhD, German Ott, MD, Andreas Rosenwald, MD, Markus Loeffler, MD, Georg Lenz, MD, Norbert Schmitz, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1589.
https://doi.org/10.1182/blood-2019-123637
Published: 2019
Journal Articles

Clinicogenetic Risk Models in Patients Randomized to Receive Consolidative Autologous Stem-Cell Transplantation after Frontline R-CHOP for Advanced Follicular Lymphoma: An Analysis from the GLSG2000 Trial

Stefan Alig, MD, Alessandro Pastore, Vindi Jurinovic, Sarah Häbe, Deepak Bararia, PhD, Verena Passerini, PhD, William Keay, Johannes Hellmuth, Andreas Rosenwald, Wolfram Klapper, MD, Harald Stein, MD PhD Dr. h.c., Alfred Feller, German Ott, MD, Annette M. Staiger, PhD, Heike Horn, Martin-Leo Hansmann, Christiane Pott, Roswitha Forstpointner, Wolf-Karsten Hofmann, Norbert Schmitz, MD, Georg Hess, Michael Unterhalt, Martin H. Dreyling, MD PhD, Anna-Katharina Zoellner, Christian Schmidt, MD, Eva Hoster, Wolfgang Hiddemann, Oliver Weigert, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4096.
https://doi.org/10.1182/blood-2018-99-118000
Published: 2018
Journal Articles

A New Stromal Signature Applicable to Formalin-Fixed Paraffin-Embedded Tissues Identifies Patients at Risk in Prospective Clinical Trials of the German High-Grade Non-Hodgkin Lymphoma Study Group

Annette M. Staiger, PhD, Michael Altenbuchinger, PhD, Marita Ziepert, PhD, Christian Kohler, PhD, Heike Horn, Michael Huttner, Katrin Huettl, MD, Wolfram Klapper, MD, Monika Szczepanowski, PhD, Julia Richter, PhD, Andreas Rosenwald, Harald Stein, MD PhD Dr. h.c., Alfred Feller, Peter Moeller, MD, Martin-Leo Hansmann, Markus Loeffler, MD, Viola Poeschel, MD, Gerhard Held, MD, Lorenz Truemper, MD, German Ott, MD, Rainer Spang, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 343.
https://doi.org/10.1182/blood-2018-99-112450
Published: 2018
Journal Articles

PARP14 Is a Novel Therapeutic Target in STAT6 mutant Follicular Lymphoma

Verena Passerini, PhD, Michael Boesl, Elisabeth Silkenstedt, MD, Elisa Osterode, Michael Heide, Robert Kridel, PhD MD, Christoph Ziegenhain, Annette M. Staiger, PhD, German Ott, MD, Monika Szczepanowski, PhD, Julia Richter, PhD, Wolfram Klapper, MD, Andreas Rosenwald, Wolfgang Enard, PhD, Wolfgang Hiddemann, Deepak Bararia, PhD, Zimber-Strobl Ursula, Dr., Oliver Weigert, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2842.
https://doi.org/10.1182/blood-2018-99-118063
Published: 2018
Journal Articles

Duodenal-type and nodal follicular lymphomas differ by their immune microenvironment rather than their mutation profiles

Clinical Trials & Observations
Johannes C. Hellmuth, Abner Louissaint, Jr, Monika Szczepanowski, Sarah Haebe, Alessandro Pastore, Stefan Alig, Annette M. Staiger, Sylvia Hartmann, Robert Kridel, Matthew D. Ducar, Peter Koch, Martin Dreyling, Martin-Leo Hansmann, German Ott, Andreas Rosenwald, Randy D. Gascoyne, David M. Weinstock, Wolfgang Hiddemann, Wolfram Klapper, Oliver Weigert
Journal: Blood
Blood (2018) 132 (16): 1695–1702.
https://doi.org/10.1182/blood-2018-03-837252
Published: 2018
Includes: Supplemental data
Journal Articles

High-grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements with diffuse large B-cell lymphoma morphology

Brief Report
David W. Scott, Rebecca L. King, Annette M. Staiger, Susana Ben-Neriah, Aixiang Jiang, Heike Horn, Anja Mottok, Pedro Farinha, Graham W. Slack, Daisuke Ennishi, Norbert Schmitz, Michael Pfreundschuh, Grzegorz S. Nowakowski, Brad S. Kahl, Joseph M. Connors, Randy D. Gascoyne, German Ott, William R. Macon, Andreas Rosenwald
Journal: Blood
Blood (2018) 131 (18): 2060–2064.
https://doi.org/10.1182/blood-2017-12-820605
Published: 2018
Includes: Supplemental data
Journal Articles

Genetically-Defined Diffuse Large B-Cell Lymphoma Subsets Arise By Distinct Pathogenetic Mechanisms and Predict Outcome

Bjoern Chapuy, MD PhD, Chip Stewart, PhD, Andrew Dunford, MS, Jaegil Kim, PhD, Atanas Kamburow, PhD, Robert A. Redd, MS, Michael Lawrence, PhD, Margaretha G.M. Roemer, MSc, Amy Li, Marita Ziepert, PhD, Annette M. Staiger, PhD, Jeremiah Wala, Matthew D. Ducar, MS, Ignaty Leshchiner, PhD, Esther Rheinbay, PhD, Amaro Taylor-Weiner, BS, Caroline Coughlin, BS, Julian Hess, Chandra Pedamallu, Dimitri Livitz, Daniel Rosebrock, Mara Rosenberg, Adam Tracy, Heike Horn, Paul van Hummelen, Andrew L Feldman, MD, Brian K Link, MD, Anne J Novak, PhD, James R. Cerhan, MD PhD, Thomas M Habermann, MD, Reiner Siebert, PhD, Andreas Rosenwald, Aaron R. Thorner, PhD, Matthew Meyerson, MDPhD, Todd R. Golub, MD, Rameen Beroukhim, Gerald Wulf, MD, German Ott, MD, Scott J. Rodig, MDPhD, Stefano Monti, PhD, Donna S. Neuberg, ScD, Markus Loeffler, MD, Michael Pfreundschuh, MD, Lorenz Trümper, MD, Gad Getz, PhD, Margaret A. Shipp, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 38.
https://doi.org/10.1182/blood.V130.Suppl_1.38.38
Published: 2017
Journal Articles

The Mutational Landscape and Immune Microenvironment of Primary Intestinal Follicular Lymphoma (PIFL)

Johannes Hellmuth, MD, Abner Louissaint, MD PhD, Monika Szczepanowski, PhD, Sarah Häbe, MD, Alessandro Pastore, MD, Annette M. Staiger, PhD, Sylvia Hartmann, Robert Kridel, Matthew D. Ducar, MS, Peter Koch, MD, Martin Dreyling, MD PhD, Martin-Leo Hansmann, MD, German Ott, MD, Andreas Rosenwald, MD, Randy D. Gascoyne, MD, David M. Weinstock, MD, Wolfgang Hiddemann, MD PhD, Wolfram Klapper, MD, Oliver Weigert, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2735.
https://doi.org/10.1182/blood.V130.Suppl_1.2735.2735
Published: 2017
Journal Articles

Sensitivity to PI3K and AKT inhibitors is mediated by divergent molecular mechanisms in subtypes of DLBCL

Tabea Erdmann, Pavel Klener, James T. Lynch, Michael Grau, Petra Vočková, Jan Molinsky, Diana Tuskova, Kevin Hudson, Urszula M. Polanska, Michael Grondine, Michele Mayo, Beiying Dai, Matthias Pfeifer, Kristian Erdmann, Daniela Schwammbach, Myroslav Zapukhlyak, Annette M. Staiger, German Ott, Wolfgang E. Berdel, Barry R. Davies, Francisco Cruzalegui, Marek Trneny, Peter Lenz, Simon T. Barry, Georg Lenz
Journal: Blood
Blood (2017) 130 (3): 310–322.
https://doi.org/10.1182/blood-2016-12-758599
Published: 2017
Includes: Supplemental data
Journal Articles

B-cell receptor–driven MALT1 activity regulates MYC signaling in mantle cell lymphoma

Beiying Dai, Michael Grau, Mélanie Juilland, Pavel Klener, Elisabeth Höring, Jan Molinsky, Gisela Schimmack, Sietse M. Aukema, Eva Hoster, Niklas Vogt, Annette M. Staiger, Tabea Erdmann, Wendan Xu, Kristian Erdmann, Nicole Dzyuba, Hannelore Madle, Wolfgang E. Berdel, Marek Trneny, Martin Dreyling, Korinna Jöhrens, Peter Lenz, Andreas Rosenwald, Reiner Siebert, Alexandar Tzankov, Wolfram Klapper, Ioannis Anagnostopoulos, Daniel Krappmann, German Ott, Margot Thome, Georg Lenz
Journal: Blood
Blood (2017) 129 (3): 333–346.
https://doi.org/10.1182/blood-2016-05-718775
Published: 2017
Includes: Supplemental data
Journal Articles

The Clinical Impact of the Cell-of-Origin Classification and the MYC+/BCL2+ Double Expresser Status in DLBCL Treated within Prospective Clinical Trials of the Dshnhl

Annette M. Staiger, PhD, Marita Ziepert, Heike Horn, PhD, David W. Scott, Thomas F. E. Barth, MD, Heinz-Wolfram Bernd, MD, Alfred C. Feller, MD, Wolfram Klapper, MD, Michael Hummel, Harald Stein, MD PhD, Dido Lenze, Martin-Leo Hansmann, MD, Sylvia Hartmann, MD, Peter Moeller, MD, Sergio Cogliatti, MD, Georg Lenz, MD, Lorenz H. Truemper, MD PhD, Markus Loeffler, MD PhD, Norbert Schmitz, MD, PhD, Michael Pfreundschuh, MD, Andreas Rosenwald, MD, German Ott
Journal: Blood
Blood (2016) 128 (22): 151.
https://doi.org/10.1182/blood.V128.22.151.151
Published: 2016
Journal Articles

B-Cell Receptor Driven MALT1 Activity Regulates MYC Signaling in Mantle Cell Lymphoma

Beiying Dai, Michael Grau, PhD, Mélanie Juilland, PhD, Pavel Klener, MD PhD, Elisabeth Höring, MD, Jan Molinsky, MD PhD, Gisela Schimmack, PhD, Sietse M Aukema, Niklas Vogt, MD, Annette M. Staiger, PhD, Tabea Erdmann, Wendan Xu, Kristian Erdmann, Wolfgang E Berdel, MD, Marek Trneny, MD, Martin H. Dreyling, MD PhD, Korinna Jöhrens, MD, Peter Lenz, PhD, Andreas Rosenwald, MD, Reiner Siebert, Alexandar Tzankov, MD, Wolfram Klapper, MD, Ioannis Anagnostopoulos, MD, Daniel Krappmann, PhD, German Ott, Margot Thome, PhD, Georg Lenz, MD
Journal: Blood
Blood (2016) 128 (22): 611.
https://doi.org/10.1182/blood.V128.22.611.611
Published: 2016
Journal Articles

Clinicogenetic risk models predict early progression of follicular lymphoma after first-line immunochemotherapy

Clinical Trials & Observations
Vindi Jurinovic, Robert Kridel, Annette M. Staiger, Monika Szczepanowski, Heike Horn, Martin H. Dreyling, Andreas Rosenwald, German Ott, Wolfram Klapper, Andrew D. Zelenetz, Paul M. Barr, Jonathan W. Friedberg, Stephen Ansell, Laurie H. Sehn, Joseph M. Connors, Randy D. Gascoyne, Wolfgang Hiddemann, Michael Unterhalt, David M. Weinstock, Oliver Weigert
Journal: Blood
Blood (2016) 128 (8): 1112–1120.
https://doi.org/10.1182/blood-2016-05-717355
Published: 2016
Includes: Supplemental data
Journal Articles

A Clinicogenetic Risk Model (m7-FLIPI) Prospectively Identifies One-Half of Patients with Early Disease Progression of Follicular Lymphoma after First-Line Immunochemotherapy

Jurinovic Vindi, Dipl Math, Robert Kridel, MD MPH, Annette M Staiger, MSc, Monika Szczepanowski, PhD, Heike Horn, PhD, Martin H. Dreyling, MD PhD, Andreas Rosenwald, MD, German Ott, MD, Wolfram Klapper, MD, Andrew D. Zelenetz, MD PhD, Jonathan W. Friedberg, MD MMSc, Stephen Ansell, MD PhD, Laurie H. Sehn, Joseph M Connors, MD, Randy D. Gascoyne, David M. Weinstock, Wolfgang Hiddemann, MD PhD, Michael Unterhalt, PhD, Eva Hoster, PhD, Oliver Weigert, MD
Journal: Blood
Blood (2015) 126 (23): 333.
https://doi.org/10.1182/blood.V126.23.333.333
Published: 2015
Journal Articles

The Phenotype High Noxa mRNA/Low NOXA Protein Levels Constitutes a Critical Achilles Heel Of Mantle Cell Lymphoma (MCL) Cells

Michael A. Dengler, Andrea Weilbacher, Matthias Gutekunst, Annette M. Staiger, Heike Horn, German Ott, MD, Heiko van der Kuip, Walter E. Aulitzky
Journal: Blood
Blood (2013) 122 (21): 644.
https://doi.org/10.1182/blood.V122.21.644.644
Published: 2013
Journal Articles

Glucocorticoids Inhibit Cell Death Induced by Oncogenic Stress After Imatinib Withdrawal In TKI Resistant p190Bcr/Abl Overexpressing Cells

Michael A. Dengler, Annette M. Staiger, Ute Hofmann, Matthias Gutekunst, Heiko van der Kuip, Walter E. Aulitzky, MD
Journal: Blood
Blood (2010) 116 (21): 3150.
https://doi.org/10.1182/blood.V116.21.3150.3150
Published: 2010