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Journal Articles

Quantitative Clonal Dynamics Define Mechanisms of CLL Evolution in Response to Combination Chemotherapy

Blood (2015) 126 (23): 362.

https://doi.org/10.1182/blood.V126.23.362.362

Published: 2015

Journal Articles

Novel Putative Driver Gene Mutations in Chronic Lymphocytic Leukemia (CLL): Results from a Combined Analysis of Whole-Exome Sequencing of 262 Primary CLL Samples

Dan A. Landau, MD PhD, Chip Stewart, PhD, Johannes G. Reiter, Michael Lawrence, PhD, Carrie Sougnez, Jennifer R. Brown, Armando Lopez-Guillermo, MD, Stacey Gabriel, PhD, Eric Lander, PhD, Donna S. Neuberg, ScD, Carlos López-Otín, Elias Campo, Gad Getz, PhD, Catherine J. Wu, MD

Blood (2014) 124 (21): 1952.

https://doi.org/10.1182/blood.V124.21.1952.1952

Published: 2014

Journal Articles

Subclonal Driver Mutations Predict Shorter Progression Free Survival in Chronic Lymphocytic Leukemia Following First-Line Chemo(immuno)Therapy: Results from the CLL8 Trial

Blood (2014) 124 (21): 1938.

https://doi.org/10.1182/blood.V124.21.1938.1938

Published: 2014

Journal Articles

Whole Genome Sequencing of Indolent CLL Reveals Novel Structural Rearrangements

Siddha Kasar, Grace Tiao, Reina Improgo, PhD, Adam Kiezun, PhD, Carrie Sougnez, Samira Bahl, PhD, Stacey M. Fernandes, Alexander R. Vartanov, Kevin Hoang, Stacey Gabriel, PhD, Dan A. Landau, MD PhD, Catherine J Wu, MD, Eric Lander, PhD, Haesook T. Kim, PhD, Gad Getz, PhD, Jennifer R. Brown, MD PhD

Blood (2014) 124 (21): 1939.

https://doi.org/10.1182/blood.V124.21.1939.1939

Published: 2014

Journal Articles

Somatic mutation as a mechanism of Wnt/β-catenin pathway activation in CLL

Blood (2014) 124 (7): 1089–1098.

https://doi.org/10.1182/blood-2014-01-552067

Published: 2014

Includes: Supplemental data

Journal Articles

Systematic identification of personal tumor-specific neoantigens in chronic lymphocytic leukemia

Mohini Rajasagi, Sachet A. Shukla, Edward F. Fritsch, Derin B. Keskin, David DeLuca, Ellese Carmona, Wandi Zhang, Carrie Sougnez, Kristian Cibulskis, John Sidney, Kristen Stevenson, Jerome Ritz, Donna Neuberg, Vladimir Brusic, Stacey Gabriel, Eric S. Lander, Gad Getz, Nir Hacohen, Catherine J. Wu

Blood (2014) 124 (3): 453–462.

https://doi.org/10.1182/blood-2014-04-567933

Published: 2014

Includes: Supplemental data

Journal Articles

Reconstructing a Genotype-Phenotype Map In Chronic Lymphocytic Leukemia

Dylan Kotliar, BA, Dan-Avi Landau, MD, PhD, Oren Litvin, BA, Petar Stojanov, Carrie Sougnez, Gordon Saksena, M. Eng, Donna S. Neuberg, ScD, Gad Getz, Jennifer R Brown, MD, PhD, Dana Pe'er, Ph.D., Nir Hacohen, PhD, Catherine J. Wu, MD

Blood (2013) 122 (21): 2857.

https://doi.org/10.1182/blood.V122.21.2857.2857

Published: 2013

Journal Articles

SF3B1 Mutation Alters The Selection Of 3' RNA Splice Sites In Chronic Lymphocytic Leukemia

Youzhong Wan, Ph. D., Angela N Brooks, Ph. D., Lili Wang, M.D., Ph.D., Carrie Sougnez, Wandi Zhang, Jessica Wong, Dan-Avi Landau, M.D., Dylan Kotliar, BA, David Deluca, Ph. D., Jennifer R. Brown, M.D., Robin Reed, Ph. D., Gad Getz, Ph.D., Matthew Meyerson, MD, PhD, Catherine J Wu, MD

Blood (2013) 122 (21): 117.

https://doi.org/10.1182/blood.V122.21.117.117

Published: 2013

Journal Articles

Increased Local Disorder of DNA Methylation Forms the Basis of High Intra-Leukemic Epigenetic Heterogeneity and Enhances CLL Evolution

Blood (2013) 122 (21): 596.

https://doi.org/10.1182/blood.V122.21.596.596

Published: 2013

Journal Articles

Clonal Evolution In Patients With Chronic Lymphocytic Leukemia (CLL) Developing Resistance To BTK Inhibition

Jan A. Burger, MD, PhD, Dan Landau, M.D., Julia Hoellenriegel, Carrie Sougnez, Matthias Schlesner, Naveed Ishaque, Benedikt Brors, Michael J. Keating, MD, William G. Wierda, MD, Kristian Cibulskis, Hagop M. Kantarjian, MD, Susan M. O'Brien, MD, Donna S. Neuberg, ScD, Thorsten Zenz, MD, Gad Getz, Catherine J Wu, MD

Blood (2013) 122 (21): 866.

https://doi.org/10.1182/blood.V122.21.866.866

Published: 2013

Journal Articles

NF-κB Pathway Mutations Modulate Cell Survival and Ibrutinib Response In Chronic Lymphocytic Leukemia

Reina Improgo, Grace Tiao, Adam Kiezun, Yaoyu Wang, Lillian Werner, Carrie Sougnez, Bethany Tesar, Stacey M Fernandes, Alexander R. Vartanov, Kevin Hoang, Donna S. Neuberg, ScD, Gad Getz, Jennifer R. Brown, M.D.

Blood (2013) 122 (21): 670.

https://doi.org/10.1182/blood.V122.21.670.670

Published: 2013

Journal Articles

The Evolution and Impact of Subclonal Mutations in Chronic Lymphocytic Leukemia

Blood (2012) 120 (21): 5.

https://doi.org/10.1182/blood.V120.21.5.5

Published: 2012

Journal Articles

Functional Somatic and Germline Variants in the NF-κB Pathway in Chronic Lymphocytic Leukemia

Ma. Reina Improgo, Adam Kiezun, Yaoyu Wang, Lillian Werner, Petar Stojanov, Dan Landau, M.D., Carrie Sougnez, Bethany Tesar, Stacey M. Fernandes, Alexander R. Vartanov, BS, Michael S. Lawrence, Kristian Cibulskis, Donna S. Neuberg, ScD, Catherine J. Wu, MD, Gad Getz, Ph.D., Jennifer R. Brown, MD, PhD

Blood (2012) 120 (21): 560.

https://doi.org/10.1182/blood.V120.21.560.560

Published: 2012

Journal Articles

Shifts in Intra-Clonal Dynamics Rather Than Novel Mutations Are the Main Engine Driving Tumor Evolution in Relapsed CLL

Dan-Avi Landau, MD, Petar Stojanov, Michael S Lawrence, Carrie Sougnez, Aaron McKeena, Scott Carter, Stacey Gabriel, Donna Neuberg, ScD, Nir Hacohen, Eric S Lander, Jennifer R. Brown, MD, PhD, Gad Getz, Cathy Wu

Blood (2011) 118 (21): 284.

https://doi.org/10.1182/blood.V118.21.284.284

Published: 2011

Journal Articles

The Mutational Landscape of Diffuse Large B Cell Lymphoma

Blood (2011) 118 (21): 259.

https://doi.org/10.1182/blood.V118.21.259.259

Published: 2011

Journal Articles

Large-Scale CLL Genome Analysis Reveals Novel Cancer Genes, Including SF3B1

Blood (2011) 118 (21): 463.

https://doi.org/10.1182/blood.V118.21.463.463

Published: 2011

Journal Articles

Novel Germline Genetic Variants Associated with Familial Chronic Lymphocytic Leukemia (CLL)

Jennifer R Brown, MD, PhD, Michael S Lawrence, Megan Hanna, Bethany Tesar, Petar Stojanov, Alexander R. Vartanov, Stacey M Fernandes, Carrie Sougnez, Laura MacConaill, Nathalie Pochet, Aviv Regev, PhD, Lillian Werner, Stacey Gabriel, Eric S Lander, Donna Neuberg, ScD, Arnold S. Freedman, MD, Gad Getz, Catherine J Wu, MD

Blood (2011) 118 (21): 465.

https://doi.org/10.1182/blood.V118.21.465.465

Published: 2011

Journal Articles

Multiple Myeloma Sequencing Reveals Subclonality and Timing of Genetic Alterations

Jens Lohr, MD, PhD, Petar Stojanov, Michael S Lawrence, Daniel Auclair, PhD, Scott Carter, Carrie Sougnez, Joshua Gould, Peter Cruz-Gordillo, Michael A Chapman, Gad Getz, Todd R. Golub, MD

Blood (2011) 118 (21): 2897.

https://doi.org/10.1182/blood.V118.21.2897.2897

Published: 2011

Journal Articles

Whole Genome Sequencing Identifies Functional Mutations In the Wnt Pathway In CLL

Lili Wang, Nathalie Pochet, Kristian Cibulskis, Wandi Zhang, Mike Lawrence, Quinlan L. Sievers, Erica Shefler, Donna Neuberg, ScD, Stacey Gabriel, Carrie Sougnez, Aviv Regev, Gad Getz, Nir Hacohen, Jennifer R Brown, MD, PhD, Catherine J Wu, MD

Blood (2010) 116 (21): 693.

https://doi.org/10.1182/blood.V116.21.693.693

Published: 2010

NARROW

Quantitative Clonal Dynamics Define Mechanisms of CLL Evolution in Response to Combination Chemotherapy

Novel Putative Driver Gene Mutations in Chronic Lymphocytic Leukemia (CLL): Results from a Combined Analysis of Whole-Exome Sequencing of 262 Primary CLL Samples

Subclonal Driver Mutations Predict Shorter Progression Free Survival in Chronic Lymphocytic Leukemia Following First-Line Chemo(immuno)Therapy: Results from the CLL8 Trial

Whole Genome Sequencing of Indolent CLL Reveals Novel Structural Rearrangements

Somatic mutation as a mechanism of Wnt/β-catenin pathway activation in CLL

Systematic identification of personal tumor-specific neoantigens in chronic lymphocytic leukemia

Reconstructing a Genotype-Phenotype Map In Chronic Lymphocytic Leukemia

SF3B1 Mutation Alters The Selection Of 3' RNA Splice Sites In Chronic Lymphocytic Leukemia

Increased Local Disorder of DNA Methylation Forms the Basis of High Intra-Leukemic Epigenetic Heterogeneity and Enhances CLL Evolution

Clonal Evolution In Patients With Chronic Lymphocytic Leukemia (CLL) Developing Resistance To BTK Inhibition

NF-κB Pathway Mutations Modulate Cell Survival and Ibrutinib Response In Chronic Lymphocytic Leukemia

The Evolution and Impact of Subclonal Mutations in Chronic Lymphocytic Leukemia

Functional Somatic and Germline Variants in the NF-κB Pathway in Chronic Lymphocytic Leukemia

Shifts in Intra-Clonal Dynamics Rather Than Novel Mutations Are the Main Engine Driving Tumor Evolution in Relapsed CLL

The Mutational Landscape of Diffuse Large B Cell Lymphoma

Large-Scale CLL Genome Analysis Reveals Novel Cancer Genes, Including SF3B1

Novel Germline Genetic Variants Associated with Familial Chronic Lymphocytic Leukemia (CLL)

Multiple Myeloma Sequencing Reveals Subclonality and Timing of Genetic Alterations

Whole Genome Sequencing Identifies Functional Mutations In the Wnt Pathway In CLL

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American Society of Hematology

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American Society of Hematology

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