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Journal Articles

Activation of the MAPK pathway mediates resistance to PI3K inhibitors in chronic lymphocytic leukemia

Ishwarya Murali, Siddha Kasar, Aishath Naeem, Svitlana Tyekucheva, Jasneet K. Khalsa, Emily M. Thrash, Gilad Itchaki, Dimitri Livitz, Ignaty Leshchiner, Shuai Dong, Stacey M. Fernandes, Gad Getz, Amy Johnson, Jennifer R. Brown
Journal: Blood
Blood (2021) 138 (1): 44–56.
https://doi.org/10.1182/blood.2020006765
Published: 2021
Includes: Supplemental data
Journal Articles

Imbalance in T Cell Subsets Triggers the Autoimmune Toxicity of PI3K Inhibitors in CLL

Deepti Gadi, PhD, Siddha Kasar, PhD, Alec Griffith, BS, Pui Yan Chiu, Svitlana Tyekucheva, PhD, Vanessa Rai, BS, Alexander R. Vartanov, MD, Stacey M. Fernandes, BS, Yang Pan, PhD, James A Lederer, PhD, Barbara Sherry, PhD, Jennifer R. Brown, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1745.
https://doi.org/10.1182/blood-2019-122961
Published: 2019
Journal Articles

Mass Cytometry Identifies T Cell Populations Associated with Severe Hepatotoxicity in CLL Patients on Upfront Idelalisib

Alexander R. Vartanov, MD, Tiago R Matos, MD, Emily M. McWilliams, PhD, Deepti Gadi, PhD, Deepak Rao, MD PhD, Siddha Kasar, PhD, Benjamin L. Lampson, MD PhD, Stacey M. Fernandes, BS, Jerome Ritz, MD PhD, Jennifer R. Brown, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4413.
https://doi.org/10.1182/blood-2018-99-118734
Published: 2018
Journal Articles

Activating MAPK Pathway Mutations Mediate Primary Resistance to PI3K Inhibitors in Chronic Lymphocytic Leukemia (CLL)

Ishwarya Murali, PhD BS, Siddha Kasar, PhD, Emily M. McWilliams, PhD, Gilad Itchaki, Svitlana Tyekucheva, PhD, Dimitri Livitz, BS, Ignaty Leshchiner, PhD, Shuai Dong, PhD, Stacey M. Fernandes, BS, Gad Getz, PhD, Amy J. Johnson, PhD, Jennifer R. Brown, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 587.
https://doi.org/10.1182/blood-2018-99-115304
Published: 2018
Journal Articles

Rare Germline Variant in NFATC4 Associated with Familial Chronic Lymphocytic Leukemia

Gilad Itchaki, Grace Tiao, PhD, Ma Reina D. Improgo, PhD, Siddha Kasar, PhD, Bethany Tesar, MS, Stacey Marie Fernandes, BS, Nathalie Pochet, PhD, Emily M McWilliams, PhD, Harrison Bai, Arnold S. Freedman, MD, Gad Getz, PhD, Jennifer R. Brown, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2993.
https://doi.org/10.1182/blood.V130.Suppl_1.2993.2993
Published: 2017
Journal Articles

Idelalisib Given Front-Line for the Treatment of Chronic Lymphocytic Leukemia Results in Frequent and Severe Immune-Mediated Toxicities

Benjamin L Lampson, MD PhD, Tiago Matos, MD MSc, Haesook T. Kim, PhD, Siddha Kasar, PhD, Elizabeth A. Morgan, MD, Masahiro Hirakawa, MD PhD, Joshua Fein, Stacey M. Fernandes, Jerome Ritz, MD, Jennifer R. Brown, MD PhD
Journal: Blood
Blood (2015) 126 (23): 497.
https://doi.org/10.1182/blood.V126.23.497.497
Published: 2015
Journal Articles

Altered Expression of Functional Proteins in CD4 Regulatory T Cells during Therapy with Idelalisib

Tiago R Matos, MD MSc, Benjamin L Lampson, MD PhD, Masahiro Hirakawa, MD PhD, Siddha Kasar, PhD, Stacey M. Fernandes, Jennifer R. Brown, MD PhD, Jerome Ritz, MD
Journal: Blood
Blood (2015) 126 (23): 1735.
https://doi.org/10.1182/blood.V126.23.1735.1735
Published: 2015
Journal Articles

Enhancer Landscapes Reveal Transcription Factor Network Dependencies in Chronic Lymphocytic Leukemia

Christopher J. Ott, PhD, Alexander J. Federation, PhD, Siddha Kasar, PhD, Josephine L. Klitgaard, MSc,PhD, Stacey M. Fernandes, Jennifer R. Brown, MD PhD, James E. Bradner, MD
Journal: Blood
Blood (2015) 126 (23): 436.
https://doi.org/10.1182/blood.V126.23.436.436
Published: 2015
Journal Articles

Comprehensive Genetic Characterization of 17p Deleted CLL Identifies Predictors of Overall Survival

Lijian Yu, Haesook T. Kim, PhD, Siddha Kasar, PhD, Parul Benien, Wei Du, Kevin Hoang, Reina Improgo, PhD, Stacey M. Fernandes, Josephine L. Klitgaard, MSc,PhD, Charles Lee, PhD, Gady Getz, Sunita R Setlur, Jennifer R. Brown, MD PhD
Journal: Blood
Blood (2015) 126 (23): 2907.
https://doi.org/10.1182/blood.V126.23.2907.2907
Published: 2015
Journal Articles

Next-Generation Sequencing Reveals Clonal Evolution at the Immunoglobulin Loci in Chronic Lymphocytic Leukemia

Jennifer R. Brown, Stacey M. Fernandes, Siddha Kasar, Kevin Hoang, Martin Moorhead, PhD, Victoria Carlton, Malek Faham, David B. Miklos, Aaron C. Logan
Journal: Blood
Blood (2014) 124 (21): 3302.
https://doi.org/10.1182/blood.V124.21.3302.3302
Published: 2014
Journal Articles

Whole Genome Sequencing of Indolent CLL Reveals Novel Structural Rearrangements

Siddha Kasar, Grace Tiao, Reina Improgo, PhD, Adam Kiezun, PhD, Carrie Sougnez, Samira Bahl, PhD, Stacey M. Fernandes, Alexander R. Vartanov, Kevin Hoang, Stacey Gabriel, PhD, Dan A. Landau, MD PhD, Catherine J Wu, MD, Eric Lander, PhD, Haesook T. Kim, PhD, Gad Getz, PhD, Jennifer R. Brown, MD PhD
Journal: Blood
Blood (2014) 124 (21): 1939.
https://doi.org/10.1182/blood.V124.21.1939.1939
Published: 2014